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The map label for this gene is pfpI [H]

Identifier: 156937189

GI number: 156937189

Start: 349120

End: 349650

Strand: Direct

Name: pfpI [H]

Synonym: Igni_0395

Alternate gene names: 156937189

Gene position: 349120-349650 (Clockwise)

Preceding gene: 156937187

Following gene: 156937191

Centisome position: 26.91

GC content: 58.76

Gene sequence:

>531_bases
TTGAGGGCCGTAATACTCGTGGGCCCCATGGTTGACGAGTACGAGGTAGTCGTCCCCTACTCCCTCTTCAAGGCGTACGG
CTTCGAGGTGGACATAGCCTCCTTCAAGGCGGGAGAGGAGGTGGTGGGGAAGAGGGGCGTCAAGCTGGAGCTGGTCCCCA
ACAAGAGCTTCTCCGAGTTAAAGGCGGACGAGTACGACGCCGTGATAATAGCCGGCGGCTACGCCCCGGACAAGGTGAGG
AGGGACGAGAACGTTAAGAGGTTCGTGAGGGAGATGTACGAGAAGGGTAAGTTGGTCTTGAGCATATGCCACGGGGGCTG
GGTGCTCATAAGCGCCGGCGTCGCTAAGGGGAAGAAGGTGACGGGGAGCAAGGGCATATGGGACGACTTGAGGAACGCCG
GCGCGGAGCCCGTGGACGAGCCCTTAGTTATAGACGGCAACGTGGTGAGCGTGAAGACTTGGAGGGAGTTCGACCACCTA
ATAAAGAACTTCGACAAGGTTCTGAAGGCGATCAAGGGTACCTCCGGCTGA

Upstream 100 bases:

>100_bases
GGTCACCGGGCTCCGGCCGAGGGCGTTGGAGCGCACAAAAAACGCGAACTTAGAGGTCCCAACTGAATAGGGCCCCCGCG
CGAAGGCCTCCGGTGGTGGC

Downstream 100 bases:

>100_bases
GCTCCGCCAGAGGGTGGCCGTGGGCGTGGAGCAAGAACTCCTTGTACCAGCCGAAGGGCGCGCAGACCACCTCGAACTCC
TCGCCGAGCCTCTCGCAAGC

Product: PfpI family intracellular peptidase

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MRAVILVGPMVDEYEVVVPYSLFKAYGFEVDIASFKAGEEVVGKRGVKLELVPNKSFSELKADEYDAVIIAGGYAPDKVR
RDENVKRFVREMYEKGKLVLSICHGGWVLISAGVAKGKKVTGSKGIWDDLRNAGAEPVDEPLVIDGNVVSVKTWREFDHL
IKNFDKVLKAIKGTSG

Sequences:

>Translated_176_residues
MRAVILVGPMVDEYEVVVPYSLFKAYGFEVDIASFKAGEEVVGKRGVKLELVPNKSFSELKADEYDAVIIAGGYAPDKVR
RDENVKRFVREMYEKGKLVLSICHGGWVLISAGVAKGKKVTGSKGIWDDLRNAGAEPVDEPLVIDGNVVSVKTWREFDHL
IKNFDKVLKAIKGTSG
>Mature_176_residues
MRAVILVGPMVDEYEVVVPYSLFKAYGFEVDIASFKAGEEVVGKRGVKLELVPNKSFSELKADEYDAVIIAGGYAPDKVR
RDENVKRFVREMYEKGKLVLSICHGGWVLISAGVAKGKKVTGSKGIWDDLRNAGAEPVDEPLVIDGNVVSVKTWREFDHL
IKNFDKVLKAIKGTSG

Specific function: Unknown

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Escherichia coli, GI87082219, Length=156, Percent_Identity=36.5384615384615, Blast_Score=97, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28571932, Length=159, Percent_Identity=27.0440251572327, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 19390; Mature: 19390

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVILVGPMVDEYEVVVPYSLFKAYGFEVDIASFKAGEEVVGKRGVKLELVPNKSFSEL
CCEEEEECCCCCCEEEEECHHHHHHCCCEEEECCCCCCHHHHCCCCCEEEEECCCCHHHC
KADEYDAVIIAGGYAPDKVRRDENVKRFVREMYEKGKLVLSICHGGWVLISAGVAKGKKV
CCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCCCC
TGSKGIWDDLRNAGAEPVDEPLVIDGNVVSVKTWREFDHLIKNFDKVLKAIKGTSG
CCCCCCHHHHHHCCCCCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRAVILVGPMVDEYEVVVPYSLFKAYGFEVDIASFKAGEEVVGKRGVKLELVPNKSFSEL
CCEEEEECCCCCCEEEEECHHHHHHCCCEEEECCCCCCHHHHCCCCCEEEEECCCCHHHC
KADEYDAVIIAGGYAPDKVRRDENVKRFVREMYEKGKLVLSICHGGWVLISAGVAKGKKV
CCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCCCC
TGSKGIWDDLRNAGAEPVDEPLVIDGNVVSVKTWREFDHLIKNFDKVLKAIKGTSG
CCCCCCHHHHHHCCCCCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]