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The map label for this gene is rpoD [H]

Identifier: 156936978

GI number: 156936978

Start: 161418

End: 162269

Strand: Direct

Name: rpoD [H]

Synonym: Igni_0183

Alternate gene names: 156936978

Gene position: 161418-162269 (Clockwise)

Preceding gene: 156936977

Following gene: 156936979

Centisome position: 12.44

GC content: 56.22

Gene sequence:

>852_bases
TTGCCCATCGAGGTGCTGGAGGAGACACCAACCTCCATACGTTTGTTAGCCAAGGGGTACCCCCTGGCGGTCCTCAACGC
GATCAGGAGGGCGGCGCTGGAGCTCGCGCCTAAAATGGCGGTCGACTTCATTGCTGTAGATAGAAACGATAGTACGTTGT
TCAACGAGGTGCTGGCGCACAGGCTCGCGATGATTCCGCTGAGGAGCGAGGAGGCGTTGGAGAGGTATGCCCCTCCGGAA
GCTTGCATGGAGTGTACGCCGGAGGAGGCAGAGGCCGATAAGTGCGTCGTCGACGGGAAGCCTTGTTACGTGCGCTTGTA
CTTAGACGCCTCGGCAGAAGGAAAACAGATCATAGTCTATTCCAAGGACTTGAAGAGCGAGGACGAGGACGTCAGGCCGG
TATACGAGAACATTCCCGTGGTCCCCTTGATAGGCGACCAGAAGGTCAAGGTAATAGCTTACGCGAGGTTGGGTAGGGGG
AGGGAACACGCCAAGTGGATGCCGGCCACCGTTTCCATAGTTAAACCCTTGCTGAAGGGGATATCCGTCAAAGAGGGCTT
GTGTGACGCCGAATGCCAAAAGGAGTGTGCGGAGAAGTGCAAGGAAGCTTTCGTGATGAAGGATGGCAAGCTCACCTTAA
AGGAGGGAACTACACTCTCTATGGTCATGTACTGTATAGAGTACGTCTGCGAGGGCAAGGGGATACGCCCGGTGTTCGAG
GAAGACACCTACTTGTTCGAGCTCGAGAGCGACGGCTCCTTGAGCGCGAGGAGGACTTTGGTTGAAGCGGCTAAGGCGGT
GGTCGAGAAGCTGAGCGAATTAAAGAACCGCCTACAGTCTCGCGAGGGGTGA

Upstream 100 bases:

>100_bases
TAGGTCGGGATTCATCATAGGGAGGATAGAGGACGTGACGCCCTTGCCCCACGACACCATACGCAGGCCCGGCGGCAGAA
GGGGCAGGAGGGTCTGAGTT

Downstream 100 bases:

>100_bases
GCGAGCGGTGCCCGCGAGGAGGAGGAAGATTACAAACGTTTTGTTAAGGAAGACGCTGGACGAGCTCTGGAAGACCAAGT
CTCCCGCGTGGAGGAGGGTC

Product: DNA-directed RNA polymerase, subunit D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MPIEVLEETPTSIRLLAKGYPLAVLNAIRRAALELAPKMAVDFIAVDRNDSTLFNEVLAHRLAMIPLRSEEALERYAPPE
ACMECTPEEAEADKCVVDGKPCYVRLYLDASAEGKQIIVYSKDLKSEDEDVRPVYENIPVVPLIGDQKVKVIAYARLGRG
REHAKWMPATVSIVKPLLKGISVKEGLCDAECQKECAEKCKEAFVMKDGKLTLKEGTTLSMVMYCIEYVCEGKGIRPVFE
EDTYLFELESDGSLSARRTLVEAAKAVVEKLSELKNRLQSREG

Sequences:

>Translated_283_residues
MPIEVLEETPTSIRLLAKGYPLAVLNAIRRAALELAPKMAVDFIAVDRNDSTLFNEVLAHRLAMIPLRSEEALERYAPPE
ACMECTPEEAEADKCVVDGKPCYVRLYLDASAEGKQIIVYSKDLKSEDEDVRPVYENIPVVPLIGDQKVKVIAYARLGRG
REHAKWMPATVSIVKPLLKGISVKEGLCDAECQKECAEKCKEAFVMKDGKLTLKEGTTLSMVMYCIEYVCEGKGIRPVFE
EDTYLFELESDGSLSARRTLVEAAKAVVEKLSELKNRLQSREG
>Mature_282_residues
PIEVLEETPTSIRLLAKGYPLAVLNAIRRAALELAPKMAVDFIAVDRNDSTLFNEVLAHRLAMIPLRSEEALERYAPPEA
CMECTPEEAEADKCVVDGKPCYVRLYLDASAEGKQIIVYSKDLKSEDEDVRPVYENIPVVPLIGDQKVKVIAYARLGRGR
EHAKWMPATVSIVKPLLKGISVKEGLCDAECQKECAEKCKEAFVMKDGKLTLKEGTTLSMVMYCIEYVCEGKGIRPVFEE
DTYLFELESDGSLSARRTLVEAAKAVVEKLSELKNRLQSREG

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0202

COG function: function code K; DNA-directed RNA polymerase, alpha subunit/40 kD subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal rpoD/eukaryotic RPB3 RNA polymerase subunit family [H]

Homologues:

Organism=Homo sapiens, GI14702171, Length=184, Percent_Identity=31.5217391304348, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI86560996, Length=185, Percent_Identity=28.6486486486486, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322168, Length=178, Percent_Identity=29.2134831460674, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17137650, Length=294, Percent_Identity=25.8503401360544, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001514
- InterPro:   IPR011261
- InterPro:   IPR011262
- InterPro:   IPR009025
- InterPro:   IPR011263
- InterPro:   IPR022842 [H]

Pfam domain/function: PF01000 RNA_pol_A_bac; PF01193 RNA_pol_L [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 31548; Mature: 31417

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIEVLEETPTSIRLLAKGYPLAVLNAIRRAALELAPKMAVDFIAVDRNDSTLFNEVLAH
CCCCCHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHH
RLAMIPLRSEEALERYAPPEACMECTPEEAEADKCVVDGKPCYVRLYLDASAEGKQIIVY
HHHHCCCCCHHHHHHCCCHHHHHHCCCCCCCCCEEEECCCCEEEEEEEECCCCCCEEEEE
SKDLKSEDEDVRPVYENIPVVPLIGDQKVKVIAYARLGRGREHAKWMPATVSIVKPLLKG
ECCCCCCCCCCCHHHHCCCEEEEECCCCEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHC
ISVKEGLCDAECQKECAEKCKEAFVMKDGKLTLKEGTTLSMVMYCIEYVCEGKGIRPVFE
CCHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCC
EDTYLFELESDGSLSARRTLVEAAKAVVEKLSELKNRLQSREG
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PIEVLEETPTSIRLLAKGYPLAVLNAIRRAALELAPKMAVDFIAVDRNDSTLFNEVLAH
CCCCHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHH
RLAMIPLRSEEALERYAPPEACMECTPEEAEADKCVVDGKPCYVRLYLDASAEGKQIIVY
HHHHCCCCCHHHHHHCCCHHHHHHCCCCCCCCCEEEECCCCEEEEEEEECCCCCCEEEEE
SKDLKSEDEDVRPVYENIPVVPLIGDQKVKVIAYARLGRGREHAKWMPATVSIVKPLLKG
ECCCCCCCCCCCHHHHCCCEEEEECCCCEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHC
ISVKEGLCDAECQKECAEKCKEAFVMKDGKLTLKEGTTLSMVMYCIEYVCEGKGIRPVFE
CCHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCC
EDTYLFELESDGSLSARRTLVEAAKAVVEKLSELKNRLQSREG
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7597027 [H]