Click here to switch to the map view.

The map label for this gene is ezrA

Identifier: 154687082

GI number: 154687082

Start: 2782447

End: 2784138

Strand: Reverse

Name: ezrA

Synonym: RBAM_026540

Alternate gene names: 154687082

Gene position: 2784138-2782447 (Counterclockwise)

Preceding gene: 154687084

Following gene: 154687080

Centisome position: 71.05

GC content: 48.23

Gene sequence:

>1692_bases
ATGGAGTTAGTCATCGGATTATTGGTTATACTGCTCGCGCTCTTTGCGGCGGGCTACTTTTTCAGGAAAAAAATTTATAC
GGAAATTGACCGGCTGGAATCATGGAAGATTGAAATTTTAAACCGTTCGATAGTGGAAGAAATGTCCAAGATCAAACATC
TGAAAATGACCGGAGAGACGGAAGAGTTCTTTGAAAGATGGCGCGAGGAGTGGGATGAAATTGTCACAGCCCATCTGCCG
AAAGTAGAAGAGCTCCTTTATGATGCCGAAGAGAACGCCGACAAATACCGGTTTAAAAAAGCGAATCAGGTGCTTGTCCA
CATCGACGACCTCCTCACTGCAGCCGAATCAAATATAGAAGGCATACTGCGTGAGATCAGCGACCTTGTGACGAGCGAGG
AAAAAAGCCGCGGAGAGATTGAACAGGTGCGTGAGCGGTATTCAAAAGCGCGGAAAAACCTTCTGGCGTACAGCCATCTC
TACGGAGAGCTTTATAACAGCCTGGAGACGGATCTCGACGAAATCTGGAGCGGCATAAAAGAGTTCGAAGAAGAGACGGA
AAGCGGCAATTACATCAAAGCGAGAAAAGTGCTGCTTGAACAGGACCGCAGACTGGATCAGCTTCAGACATACATAGATG
ACGTTCCGAAACTGCTCGCCGACTGTAAACAGACCGTGCCGAACCAAATTGCCAAGCTGAAAGACGGCTACCGGGAAATG
ACGGAAAAAGGCTACAAATTGGAGCATATTCAAATCGAAAAAGAGCTGGATACACTCACAAATCAAGTGAAACGGGCCGA
AAACGCGCTACTAGAAGAATTGGATGTCGACGAAGCGTCCGCCATCCTTCAGCTGATTGATGAAACCATTCAATCGATGT
ATGAACAGCTGGAAGGCGAAGTGGAAGCCGGACAGTCCGTATTAAGCAAAATGCCTGAGCTGATCATCGCGTATGAAAAG
CTTGAGGAAGAAAAAGACCGCACAAAAACCGAAACGGAGCTCGTCAAGGAAAGCTATCAGCTGACGGCAGGAGAAATCGG
CAGACAGCATGCCTTCGAAAAACAGCTGGAAACGATCGGCCGGCTCCTTGAGCAGGCGAGAGAAAAGCTTGACGGCGAGC
ATGTCGCTTACTCGCTGCTGATTGAAGAAGTCGAGGCCATCGAAAAGCAGCTGGAAGAGGCTCAGAAAGAACATGCCGAA
TACCGTGAAAATCTGCAGGCGCTCAGAAAAGAAGAACTGCAGGCGCGGGAAACGCTGATGCATCTTCGGAAAACCATTTC
TGACACGGCCCGAATGCTGCAAAAAAGCAACGTGCCGGGAATTCCTGAACAAGTCAAGGACAAGCTCGAGACGGCAAATC
ATCATATAGAAGAAACCGTCAGCCAATTGGAAGAGCTGCCGCTGAACATGGAGGAAGCCGCCAAACATCTGGATGAAGCC
GAAAAGGTGGTTGAGGAAGTCAGCGAAGAGGCGGAAGATCTTGTGATTCAGGTGAAGCTGATTGAGCGGATCATCCAATA
CGGCAACCGCTTCCGAAGCCAGAATCATATTTTATCCGAACAGCTGAAAGAAGCGGAACGGCTGTTTTATGCTTACAGCT
ATAATGAAGCTTATGAGATGGCGGCAGATGCTGTTGAAAAAGCAGCTCCCGGCGCCGTGAAAAAAATTAAAGCTGATCAA
TCTGCTTCATAG

Upstream 100 bases:

>100_bases
ATAACAATGAAAACGACAGATTTTCTCAATACATATATTGAAATCTTTCTGAATACATAAAACACCCTGACAGATTAAGA
GAACAACAAGGGGGCTCATT

Downstream 100 bases:

>100_bases
ACGCATAAGCAAAAACTGCACCCTGATGGAAATCAGAGGTGCAGTTTTTTAGTTTCTCACGGAATATAAAAAGCGCCTGC
GGCTGATATACATCAAACCG

Product: septation ring formation regulator EzrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MELVIGLLVILLALFAAGYFFRKKIYTEIDRLESWKIEILNRSIVEEMSKIKHLKMTGETEEFFERWREEWDEIVTAHLP
KVEELLYDAEENADKYRFKKANQVLVHIDDLLTAAESNIEGILREISDLVTSEEKSRGEIEQVRERYSKARKNLLAYSHL
YGELYNSLETDLDEIWSGIKEFEEETESGNYIKARKVLLEQDRRLDQLQTYIDDVPKLLADCKQTVPNQIAKLKDGYREM
TEKGYKLEHIQIEKELDTLTNQVKRAENALLEELDVDEASAILQLIDETIQSMYEQLEGEVEAGQSVLSKMPELIIAYEK
LEEEKDRTKTETELVKESYQLTAGEIGRQHAFEKQLETIGRLLEQAREKLDGEHVAYSLLIEEVEAIEKQLEEAQKEHAE
YRENLQALRKEELQARETLMHLRKTISDTARMLQKSNVPGIPEQVKDKLETANHHIEETVSQLEELPLNMEEAAKHLDEA
EKVVEEVSEEAEDLVIQVKLIERIIQYGNRFRSQNHILSEQLKEAERLFYAYSYNEAYEMAADAVEKAAPGAVKKIKADQ
SAS

Sequences:

>Translated_563_residues
MELVIGLLVILLALFAAGYFFRKKIYTEIDRLESWKIEILNRSIVEEMSKIKHLKMTGETEEFFERWREEWDEIVTAHLP
KVEELLYDAEENADKYRFKKANQVLVHIDDLLTAAESNIEGILREISDLVTSEEKSRGEIEQVRERYSKARKNLLAYSHL
YGELYNSLETDLDEIWSGIKEFEEETESGNYIKARKVLLEQDRRLDQLQTYIDDVPKLLADCKQTVPNQIAKLKDGYREM
TEKGYKLEHIQIEKELDTLTNQVKRAENALLEELDVDEASAILQLIDETIQSMYEQLEGEVEAGQSVLSKMPELIIAYEK
LEEEKDRTKTETELVKESYQLTAGEIGRQHAFEKQLETIGRLLEQAREKLDGEHVAYSLLIEEVEAIEKQLEEAQKEHAE
YRENLQALRKEELQARETLMHLRKTISDTARMLQKSNVPGIPEQVKDKLETANHHIEETVSQLEELPLNMEEAAKHLDEA
EKVVEEVSEEAEDLVIQVKLIERIIQYGNRFRSQNHILSEQLKEAERLFYAYSYNEAYEMAADAVEKAAPGAVKKIKADQ
SAS
>Mature_563_residues
MELVIGLLVILLALFAAGYFFRKKIYTEIDRLESWKIEILNRSIVEEMSKIKHLKMTGETEEFFERWREEWDEIVTAHLP
KVEELLYDAEENADKYRFKKANQVLVHIDDLLTAAESNIEGILREISDLVTSEEKSRGEIEQVRERYSKARKNLLAYSHL
YGELYNSLETDLDEIWSGIKEFEEETESGNYIKARKVLLEQDRRLDQLQTYIDDVPKLLADCKQTVPNQIAKLKDGYREM
TEKGYKLEHIQIEKELDTLTNQVKRAENALLEELDVDEASAILQLIDETIQSMYEQLEGEVEAGQSVLSKMPELIIAYEK
LEEEKDRTKTETELVKESYQLTAGEIGRQHAFEKQLETIGRLLEQAREKLDGEHVAYSLLIEEVEAIEKQLEEAQKEHAE
YRENLQALRKEELQARETLMHLRKTISDTARMLQKSNVPGIPEQVKDKLETANHHIEETVSQLEELPLNMEEAAKHLDEA
EKVVEEVSEEAEDLVIQVKLIERIIQYGNRFRSQNHILSEQLKEAERLFYAYSYNEAYEMAADAVEKAAPGAVKKIKADQ
SAS

Specific function: Negative regulator of ftsZ ring formation; modulates the frequency and position of ftsZ ring formation. Inhibits ftsZ ring formation at polar sites. Interacts either with ftsZ or with one of its binding partners to promote depolymerization

COG id: COG4477

COG function: function code D; Negative regulator of septation ring formation

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein. Note=Colocalized with ftsZ to the nascent septal site (By similarity)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ezrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EZRA_BACA2 (A7Z7N6)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001422243.1
- ProteinModelPortal:   A7Z7N6
- STRING:   A7Z7N6
- EnsemblBacteria:   EBBACT00000006807
- GeneID:   5463056
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_026540
- eggNOG:   COG4477
- GeneTree:   EBGT00050000000289
- HOGENOM:   HBG345654
- OMA:   MDIQELH
- ProtClustDB:   PRK04778
- BioCyc:   BAMY326423:RBAM_026540-MONOMER
- HAMAP:   MF_00728
- InterPro:   IPR010379

Pfam domain/function: PF06160 EzrA

EC number: NA

Molecular weight: Translated: 65385; Mature: 65385

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11dbef58)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVIGLLVILLALFAAGYFFRKKIYTEIDRLESWKIEILNRSIVEEMSKIKHLKMTGET
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EEFFERWREEWDEIVTAHLPKVEELLYDAEENADKYRFKKANQVLVHIDDLLTAAESNIE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GILREISDLVTSEEKSRGEIEQVRERYSKARKNLLAYSHLYGELYNSLETDLDEIWSGIK
HHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EFEEETESGNYIKARKVLLEQDRRLDQLQTYIDDVPKLLADCKQTVPNQIAKLKDGYREM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEKGYKLEHIQIEKELDTLTNQVKRAENALLEELDVDEASAILQLIDETIQSMYEQLEGE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCH
VEAGQSVLSKMPELIIAYEKLEEEKDRTKTETELVKESYQLTAGEIGRQHAFEKQLETIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLEQAREKLDGEHVAYSLLIEEVEAIEKQLEEAQKEHAEYRENLQALRKEELQARETLM
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLRKTISDTARMLQKSNVPGIPEQVKDKLETANHHIEETVSQLEELPLNMEEAAKHLDEA
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EKVVEEVSEEAEDLVIQVKLIERIIQYGNRFRSQNHILSEQLKEAERLFYAYSYNEAYEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AADAVEKAAPGAVKKIKADQSAS
HHHHHHHHCCCHHHHHCCCCCCH
>Mature Secondary Structure
MELVIGLLVILLALFAAGYFFRKKIYTEIDRLESWKIEILNRSIVEEMSKIKHLKMTGET
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EEFFERWREEWDEIVTAHLPKVEELLYDAEENADKYRFKKANQVLVHIDDLLTAAESNIE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GILREISDLVTSEEKSRGEIEQVRERYSKARKNLLAYSHLYGELYNSLETDLDEIWSGIK
HHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EFEEETESGNYIKARKVLLEQDRRLDQLQTYIDDVPKLLADCKQTVPNQIAKLKDGYREM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEKGYKLEHIQIEKELDTLTNQVKRAENALLEELDVDEASAILQLIDETIQSMYEQLEGE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCH
VEAGQSVLSKMPELIIAYEKLEEEKDRTKTETELVKESYQLTAGEIGRQHAFEKQLETIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLEQAREKLDGEHVAYSLLIEEVEAIEKQLEEAQKEHAEYRENLQALRKEELQARETLM
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLRKTISDTARMLQKSNVPGIPEQVKDKLETANHHIEETVSQLEELPLNMEEAAKHLDEA
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EKVVEEVSEEAEDLVIQVKLIERIIQYGNRFRSQNHILSEQLKEAERLFYAYSYNEAYEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AADAVEKAAPGAVKKIKADQSAS
HHHHHHHHCCCHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA