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The map label for this gene is nifZ [H]

Identifier: 154687080

GI number: 154687080

Start: 2779654

End: 2780799

Strand: Reverse

Name: nifZ [H]

Synonym: RBAM_026520

Alternate gene names: 154687080

Gene position: 2780799-2779654 (Counterclockwise)

Preceding gene: 154687082

Following gene: 154687079

Centisome position: 70.96

GC content: 50.26

Gene sequence:

>1146_bases
ATGATATATTTAGACAACAGCTCAACGACCGAGCCGTATGAAGAGGTATTGGATGTGTACAAACAGACGAGCAGCCGTTA
TTTCGGCAATCCTTCGTCTCTGCACCGGTTAGGAACTGAGACGGAACAGCTCCTTGAAGCGGCCGCTCAGCAAATAAAAA
AAACCTTGCGTTTAAAAAATTATGATATTGTATTTACATCAGGCGCGACTGAAGCGAATAACGCTGCGTTAAAGGGAGCA
GCCTGGGCAAACATGAGTAAAGGGAGACATATCATTGCTTCGGCGATTGAGCATCCTTCTGTGACGGAGACGCTTGATCA
GCTGACAGAGCTGTTCGGCTTTGAAGTCACATATCTTCCGGCCGATCAAAACGGCTTCGTCTCTTTGAAAGACGTCAAAT
CGGCTATCAGGCCGGATACGATAATCGTCAGCGTCATGCATGTCAATAACGAAGTCGGCTCCATTCAGCCCGTAAAGGAA
ATCGGCGGGTTTTTGAAGCAGCACCGGAATATTCTGTTTCATGTTGATCATGTGCAGGGCATTCATAAAGTTCCGCTGTC
TATAGAAGAAGCGGGCATTGACCTTTGCACCGTTTCAGGGCATAAGTTTCACGGCTTAAAAGGGACAGGAGCGCTTATCG
TCAAAAAAGGAACGCGGCTCATTCCGCTTATCACGGGCGGCTCGCAGCAAAAAGGCGTCCGAGCCGGAACGGAACACACG
GCAGGCGCCGTTTCCCTTGCGAAAGCGATCAATCTTTCCGCGCGTGACATGAACGAGCGGCTTTCTTCCGTGGAGGCTGC
CAAGAATGCGCTCATGGAAAGGCTGAGCGGGACGGACGGGGTCGTCATCAACACCCCCGCTGAAAACAGCGCGCCGCATA
TCATTAATTTTTCCGTTCCGGGCGTGAAGGCGGAAGTGCTGTTGCACATGCTTGAGGAAAAAGGAATATATGTCTCCACA
ACCTCGGCATGTTCGGCAAGAGAGCACAAACCGAGCCGTGTTCTCCTGCAGATGAATAAAGGCGAACAGATTGCATCAAG
CAGCATAAGAGTCAGCCTGAACTTCAGCCATACGGCTGACATCACGGAGCCGTTTATGGCCGCGCTGGTGCCGGCTGTTC
AAAAACTAAAAAAAATGATGAGGTAG

Upstream 100 bases:

>100_bases
AGAGAAGTCAATACTCGATTTATTGCGAATTTATATTTACTTTTGTTATGGTAGCATAAATATCATACGATGTACCGTTT
TCATTAAAGGAGTAAAAAAA

Downstream 100 bases:

>100_bases
CATATGAATTACGATCATATTTTAATCCGTTTTGGTGAAATATCCACAAAAGGAAAAAACAGACGCAGTTTTATTGAAAG
ATTAAAACAGAATATCCGCC

Product: NifZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MIYLDNSSTTEPYEEVLDVYKQTSSRYFGNPSSLHRLGTETEQLLEAAAQQIKKTLRLKNYDIVFTSGATEANNAALKGA
AWANMSKGRHIIASAIEHPSVTETLDQLTELFGFEVTYLPADQNGFVSLKDVKSAIRPDTIIVSVMHVNNEVGSIQPVKE
IGGFLKQHRNILFHVDHVQGIHKVPLSIEEAGIDLCTVSGHKFHGLKGTGALIVKKGTRLIPLITGGSQQKGVRAGTEHT
AGAVSLAKAINLSARDMNERLSSVEAAKNALMERLSGTDGVVINTPAENSAPHIINFSVPGVKAEVLLHMLEEKGIYVST
TSACSAREHKPSRVLLQMNKGEQIASSSIRVSLNFSHTADITEPFMAALVPAVQKLKKMMR

Sequences:

>Translated_381_residues
MIYLDNSSTTEPYEEVLDVYKQTSSRYFGNPSSLHRLGTETEQLLEAAAQQIKKTLRLKNYDIVFTSGATEANNAALKGA
AWANMSKGRHIIASAIEHPSVTETLDQLTELFGFEVTYLPADQNGFVSLKDVKSAIRPDTIIVSVMHVNNEVGSIQPVKE
IGGFLKQHRNILFHVDHVQGIHKVPLSIEEAGIDLCTVSGHKFHGLKGTGALIVKKGTRLIPLITGGSQQKGVRAGTEHT
AGAVSLAKAINLSARDMNERLSSVEAAKNALMERLSGTDGVVINTPAENSAPHIINFSVPGVKAEVLLHMLEEKGIYVST
TSACSAREHKPSRVLLQMNKGEQIASSSIRVSLNFSHTADITEPFMAALVPAVQKLKKMMR
>Mature_381_residues
MIYLDNSSTTEPYEEVLDVYKQTSSRYFGNPSSLHRLGTETEQLLEAAAQQIKKTLRLKNYDIVFTSGATEANNAALKGA
AWANMSKGRHIIASAIEHPSVTETLDQLTELFGFEVTYLPADQNGFVSLKDVKSAIRPDTIIVSVMHVNNEVGSIQPVKE
IGGFLKQHRNILFHVDHVQGIHKVPLSIEEAGIDLCTVSGHKFHGLKGTGALIVKKGTRLIPLITGGSQQKGVRAGTEHT
AGAVSLAKAINLSARDMNERLSSVEAAKNALMERLSGTDGVVINTPAENSAPHIINFSVPGVKAEVLLHMLEEKGIYVST
TSACSAREHKPSRVLLQMNKGEQIASSSIRVSLNFSHTADITEPFMAALVPAVQKLKKMMR

Specific function: Catalyzes the removal of elemental sulfur from cysteine to produce alanine [H]

COG id: COG1104

COG function: function code E; Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=382, Percent_Identity=35.8638743455497, Blast_Score=229, Evalue=5e-60,
Organism=Homo sapiens, GI156713448, Length=393, Percent_Identity=30.5343511450382, Blast_Score=164, Evalue=1e-40,
Organism=Escherichia coli, GI48994898, Length=357, Percent_Identity=39.2156862745098, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1787970, Length=345, Percent_Identity=22.6086956521739, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789175, Length=346, Percent_Identity=24.2774566473988, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25143064, Length=373, Percent_Identity=35.3887399463807, Blast_Score=207, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI17533177, Length=328, Percent_Identity=32.0121951219512, Blast_Score=128, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6319831, Length=384, Percent_Identity=36.1979166666667, Blast_Score=223, Evalue=3e-59,
Organism=Drosophila melanogaster, GI20129463, Length=382, Percent_Identity=37.696335078534, Blast_Score=233, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR016454
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 41340; Mature: 41340

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYLDNSSTTEPYEEVLDVYKQTSSRYFGNPSSLHRLGTETEQLLEAAAQQIKKTLRLKN
CEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
YDIVFTSGATEANNAALKGAAWANMSKGRHIIASAIEHPSVTETLDQLTELFGFEVTYLP
CEEEEECCCCCCCCCEECCCHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEE
ADQNGFVSLKDVKSAIRPDTIIVSVMHVNNEVGSIQPVKEIGGFLKQHRNILFHVDHVQG
CCCCCCEEHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEHHHCC
IHKVPLSIEEAGIDLCTVSGHKFHGLKGTGALIVKKGTRLIPLITGGSQQKGVRAGTEHT
HHHCCCCHHHCCCEEEEECCCEECCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCCC
AGAVSLAKAINLSARDMNERLSSVEAAKNALMERLSGTDGVVINTPAENSAPHIINFSVP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCC
GVKAEVLLHMLEEKGIYVSTTSACSAREHKPSRVLLQMNKGEQIASSSIRVSLNFSHTAD
CHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCC
ITEPFMAALVPAVQKLKKMMR
CHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MIYLDNSSTTEPYEEVLDVYKQTSSRYFGNPSSLHRLGTETEQLLEAAAQQIKKTLRLKN
CEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
YDIVFTSGATEANNAALKGAAWANMSKGRHIIASAIEHPSVTETLDQLTELFGFEVTYLP
CEEEEECCCCCCCCCEECCCHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEE
ADQNGFVSLKDVKSAIRPDTIIVSVMHVNNEVGSIQPVKEIGGFLKQHRNILFHVDHVQG
CCCCCCEEHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEHHHCC
IHKVPLSIEEAGIDLCTVSGHKFHGLKGTGALIVKKGTRLIPLITGGSQQKGVRAGTEHT
HHHCCCCHHHCCCEEEEECCCEECCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCCC
AGAVSLAKAINLSARDMNERLSSVEAAKNALMERLSGTDGVVINTPAENSAPHIINFSVP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCC
GVKAEVLLHMLEEKGIYVSTTSACSAREHKPSRVLLQMNKGEQIASSSIRVSLNFSHTAD
CHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCC
ITEPFMAALVPAVQKLKKMMR
CHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]