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The map label for this gene is coaE [H]

Identifier: 154687038

GI number: 154687038

Start: 2733623

End: 2734216

Strand: Reverse

Name: coaE [H]

Synonym: RBAM_026100

Alternate gene names: 154687038

Gene position: 2734216-2733623 (Counterclockwise)

Preceding gene: 154687039

Following gene: 154687035

Centisome position: 69.78

GC content: 48.15

Gene sequence:

>594_bases
TTGAGCTTGGTCATCGGTTTAACGGGAGGCATCGCAAGCGGCAAAAGCACGGTAGCGCGTATGCTGATCGACAAAAAAAT
AACAGTCATTGATGCGGATGCCATCGCAAAACAGGCGGTGGAAAAAGGAATGCCGGCTTACGGACAAATTGTGGAAGCAT
TCGGAAAAGACATCCTGCTGGAAAATGGCGATATTGACAGAAAAAAACTCGGTTCTATCGTTTTCACTGACGAACAGAAG
CGTCTGAAGCTGAATCAGATCGTTCATCCGGCGGTGCGTGCGGAAATGCTGAAACAGCGGGATGAAGCCGTTGCGCGAAA
AGAGCAGTTCGTCGTTTTGGATATACCGCTTTTGTATGAAAGCGGGCTTGATTATCTTGTCGGCAAGGTGCTCGTCGTCA
CCGTACCGGCAGACATTCAGCTTAAACGGCTGATGGAGCGGAATTCCCTTACAGAAGAAGAAGCGATGAGCCGGATAACG
TCACAAATGCCTTTAACGGATAAAACAAAAAAAGCTGACGCCGTCATTGATAACAGCGGCAGTCTTGAATATACAAAGCA
CCAGCTTGAGGAAGTATTGAGCGGCTGGGCATAA

Upstream 100 bases:

>100_bases
TTTGCTTTCAAGATGGAATTGGATAGATAAAATGACATTTTTGCCGGGAGTCCTGCTGATTATCATCGGGATTTGGAAAA
TGTAAGAAGGAGTGGGCTTT

Downstream 100 bases:

>100_bases
ACAAACACCGTTCGGAAAGCCGAACGGTGTTTTTCTGGTTAAAAATCAAAATTGTCAGGGTCCGGACCGACACGGAGGTT
TTCGTTCAGATCATCAATCC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MSLVIGLTGGIASGKSTVARMLIDKKITVIDADAIAKQAVEKGMPAYGQIVEAFGKDILLENGDIDRKKLGSIVFTDEQK
RLKLNQIVHPAVRAEMLKQRDEAVARKEQFVVLDIPLLYESGLDYLVGKVLVVTVPADIQLKRLMERNSLTEEEAMSRIT
SQMPLTDKTKKADAVIDNSGSLEYTKHQLEEVLSGWA

Sequences:

>Translated_197_residues
MSLVIGLTGGIASGKSTVARMLIDKKITVIDADAIAKQAVEKGMPAYGQIVEAFGKDILLENGDIDRKKLGSIVFTDEQK
RLKLNQIVHPAVRAEMLKQRDEAVARKEQFVVLDIPLLYESGLDYLVGKVLVVTVPADIQLKRLMERNSLTEEEAMSRIT
SQMPLTDKTKKADAVIDNSGSLEYTKHQLEEVLSGWA
>Mature_196_residues
SLVIGLTGGIASGKSTVARMLIDKKITVIDADAIAKQAVEKGMPAYGQIVEAFGKDILLENGDIDRKKLGSIVFTDEQKR
LKLNQIVHPAVRAEMLKQRDEAVARKEQFVVLDIPLLYESGLDYLVGKVLVVTVPADIQLKRLMERNSLTEEEAMSRITS
QMPLTDKTKKADAVIDNSGSLEYTKHQLEEVLSGWA

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=189, Percent_Identity=47.6190476190476, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI191252795, Length=189, Percent_Identity=47.6190476190476, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI110227607, Length=194, Percent_Identity=36.5979381443299, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI205277394, Length=194, Percent_Identity=36.5979381443299, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI110227605, Length=194, Percent_Identity=36.5979381443299, Blast_Score=114, Evalue=4e-26,
Organism=Homo sapiens, GI110227603, Length=194, Percent_Identity=36.5979381443299, Blast_Score=114, Evalue=4e-26,
Organism=Homo sapiens, GI110227601, Length=194, Percent_Identity=36.5979381443299, Blast_Score=114, Evalue=4e-26,
Organism=Escherichia coli, GI1786292, Length=181, Percent_Identity=38.121546961326, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17554944, Length=194, Percent_Identity=36.5979381443299, Blast_Score=146, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI25143409, Length=188, Percent_Identity=31.9148936170213, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320402, Length=196, Percent_Identity=42.8571428571429, Blast_Score=153, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24644728, Length=183, Percent_Identity=43.7158469945355, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24658602, Length=189, Percent_Identity=37.5661375661376, Blast_Score=124, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21738; Mature: 21606

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVIGLTGGIASGKSTVARMLIDKKITVIDADAIAKQAVEKGMPAYGQIVEAFGKDILL
CEEEEEECCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHCCCEEE
ENGDIDRKKLGSIVFTDEQKRLKLNQIVHPAVRAEMLKQRDEAVARKEQFVVLDIPLLYE
CCCCCCHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHH
SGLDYLVGKVLVVTVPADIQLKRLMERNSLTEEEAMSRITSQMPLTDKTKKADAVIDNSG
CCHHHHHHCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCC
SLEYTKHQLEEVLSGWA
CCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLVIGLTGGIASGKSTVARMLIDKKITVIDADAIAKQAVEKGMPAYGQIVEAFGKDILL
EEEEEECCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHCCCEEE
ENGDIDRKKLGSIVFTDEQKRLKLNQIVHPAVRAEMLKQRDEAVARKEQFVVLDIPLLYE
CCCCCCHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHH
SGLDYLVGKVLVVTVPADIQLKRLMERNSLTEEEAMSRITSQMPLTDKTKKADAVIDNSG
CCHHHHHHCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCC
SLEYTKHQLEEVLSGWA
CCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]