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The map label for this gene is gapB [H]

Identifier: 154687034

GI number: 154687034

Start: 2729683

End: 2730705

Strand: Reverse

Name: gapB [H]

Synonym: RBAM_026060

Alternate gene names: 154687034

Gene position: 2730705-2729683 (Counterclockwise)

Preceding gene: 154687035

Following gene: 154687033

Centisome position: 69.69

GC content: 46.53

Gene sequence:

>1023_bases
ATGAAGGTAAAAGTAGCAATCAACGGGTTTGGAAGAATCGGAAGAATGGTGTTCAGAAAAGCAATGGAAGATGATCAAAT
TCAAATAACAGCCATTAATGCAAGCTATCCCCCGGAAACGCTTGCTCATTTGATAAAGTATGACACAATTCACGGCAAAT
ACGATCAAGAAGTTGAGACCTCCGACGACAGTCTGATCGTCAACGGAAAACATATTATGCTGTTCAATCGCCGGGATCCG
AGAGAGCTTCCGTGGAAAGAATGCGGAATAGACATCGTCGTAGAGGCAACGGGGAAATTTAATTCAAAAGAAAAAGCAAT
GAGCCATATTGAAGCAGGGGCGAAAAAAGTCATTTTAACGGCTCCGGGCAAAAATGAAGACGTTACCATTGTCATGGGAG
TAAATGAAGAGCAGTTCAATCCCGATGAACATGTCATTATTTCAAATGCATCCTGCACGACAAACTGTCTTGCGCCGGTC
GTCAAAGTGCTTGATCAGGAATTCGGGATTGAAAGCGGCCTGATGACGACTGTTCACGCTTACACGAATGATCAAAAAAA
TATCGACAATCCGCATAAAGATCTGCGGAGGGCGAGAGCGTGCGGAGAATCCATCATTCCGACTTCTACAGGCGCCGCCA
AAGCGCTGTCGCTCGTGCTTCCTCATTTGAAAGGAAAACTTCACGGTCTCGCTTTGCGTGTTCCCGTTCCGAATGTGTCA
TTAGTGGACCTTGTCTGCGATATGAAAACAGATGTGTCGGCCGAGCAAGTGAACGCCGCTTTCCAAAGAGCCGCAAAAAC
GTCGATGTACGGAATTCTTGATTATTCGGATGAACCGCTCGTTTCTTCGGATTATAATACGAATTCACACTCTGCGATCA
TCGACGGTCTGACAACGATGGTGATGGAAGACCGAAAAGTAAAGGTGCTCGCCTGGTATGACAATGAATGGGGATATTCC
TGCCGGGTCGTTGATCTTATCCGTCACGTCGCCGCGCGAATGAAACACCCGTCAGCTGTGTAG

Upstream 100 bases:

>100_bases
GATTTTTATCAAGTTGTACTGGCGGATTTCTTTTAATGTGTTATACTATATATAAATAAAGGTAAATTAGAGTGGCATAT
TAAAAAGGGGTGACCTGAGC

Downstream 100 bases:

>100_bases
ACTAAAGATCATGGACATTTGTTAGAAAAAAACCCTTAACGGCATATTCGCAAAAAACACACCTTGCAAAATAAACTTAA
ACACAGTATACTATCTTTCG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; GAPDH [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKVKVAINGFGRIGRMVFRKAMEDDQIQITAINASYPPETLAHLIKYDTIHGKYDQEVETSDDSLIVNGKHIMLFNRRDP
RELPWKECGIDIVVEATGKFNSKEKAMSHIEAGAKKVILTAPGKNEDVTIVMGVNEEQFNPDEHVIISNASCTTNCLAPV
VKVLDQEFGIESGLMTTVHAYTNDQKNIDNPHKDLRRARACGESIIPTSTGAAKALSLVLPHLKGKLHGLALRVPVPNVS
LVDLVCDMKTDVSAEQVNAAFQRAAKTSMYGILDYSDEPLVSSDYNTNSHSAIIDGLTTMVMEDRKVKVLAWYDNEWGYS
CRVVDLIRHVAARMKHPSAV

Sequences:

>Translated_340_residues
MKVKVAINGFGRIGRMVFRKAMEDDQIQITAINASYPPETLAHLIKYDTIHGKYDQEVETSDDSLIVNGKHIMLFNRRDP
RELPWKECGIDIVVEATGKFNSKEKAMSHIEAGAKKVILTAPGKNEDVTIVMGVNEEQFNPDEHVIISNASCTTNCLAPV
VKVLDQEFGIESGLMTTVHAYTNDQKNIDNPHKDLRRARACGESIIPTSTGAAKALSLVLPHLKGKLHGLALRVPVPNVS
LVDLVCDMKTDVSAEQVNAAFQRAAKTSMYGILDYSDEPLVSSDYNTNSHSAIIDGLTTMVMEDRKVKVLAWYDNEWGYS
CRVVDLIRHVAARMKHPSAV
>Mature_340_residues
MKVKVAINGFGRIGRMVFRKAMEDDQIQITAINASYPPETLAHLIKYDTIHGKYDQEVETSDDSLIVNGKHIMLFNRRDP
RELPWKECGIDIVVEATGKFNSKEKAMSHIEAGAKKVILTAPGKNEDVTIVMGVNEEQFNPDEHVIISNASCTTNCLAPV
VKVLDQEFGIESGLMTTVHAYTNDQKNIDNPHKDLRRARACGESIIPTSTGAAKALSLVLPHLKGKLHGLALRVPVPNVS
LVDLVCDMKTDVSAEQVNAAFQRAAKTSMYGILDYSDEPLVSSDYNTNSHSAIIDGLTTMVMEDRKVKVLAWYDNEWGYS
CRVVDLIRHVAARMKHPSAV

Specific function: More active in anabolism [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=336, Percent_Identity=45.8333333333333, Blast_Score=318, Evalue=5e-87,
Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=45.5089820359281, Blast_Score=312, Evalue=3e-85,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=49.3975903614458, Blast_Score=337, Evalue=8e-94,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=46.2006079027356, Blast_Score=310, Evalue=7e-86,
Organism=Caenorhabditis elegans, GI17534677, Length=339, Percent_Identity=46.3126843657817, Blast_Score=310, Evalue=8e-85,
Organism=Caenorhabditis elegans, GI17534679, Length=339, Percent_Identity=46.6076696165192, Blast_Score=310, Evalue=9e-85,
Organism=Caenorhabditis elegans, GI32566163, Length=339, Percent_Identity=45.7227138643068, Blast_Score=303, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=45.7227138643068, Blast_Score=303, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=47.7341389728097, Blast_Score=325, Evalue=9e-90,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=47.7341389728097, Blast_Score=323, Evalue=2e-89,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=46.5256797583082, Blast_Score=322, Evalue=5e-89,
Organism=Drosophila melanogaster, GI17933600, Length=332, Percent_Identity=44.8795180722892, Blast_Score=304, Evalue=5e-83,
Organism=Drosophila melanogaster, GI18110149, Length=332, Percent_Identity=44.8795180722892, Blast_Score=304, Evalue=5e-83,
Organism=Drosophila melanogaster, GI85725000, Length=332, Percent_Identity=44.2771084337349, Blast_Score=303, Evalue=1e-82,
Organism=Drosophila melanogaster, GI22023983, Length=332, Percent_Identity=44.2771084337349, Blast_Score=303, Evalue=1e-82,
Organism=Drosophila melanogaster, GI19922412, Length=327, Percent_Identity=44.954128440367, Blast_Score=300, Evalue=1e-81,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.59 [H]

Molecular weight: Translated: 37616; Mature: 37616

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKVAINGFGRIGRMVFRKAMEDDQIQITAINASYPPETLAHLIKYDTIHGKYDQEVET
CEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCC
SDDSLIVNGKHIMLFNRRDPRELPWKECGIDIVVEATGKFNSKEKAMSHIEAGAKKVILT
CCCEEEEECCEEEEEECCCCCCCCHHHCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEE
APGKNEDVTIVMGVNEEQFNPDEHVIISNASCTTNCLAPVVKVLDQEFGIESGLMTTVHA
CCCCCCCEEEEEECCHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEE
YTNDQKNIDNPHKDLRRARACGESIIPTSTGAAKALSLVLPHLKGKLHGLALRVPVPNVS
ECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCC
LVDLVCDMKTDVSAEQVNAAFQRAAKTSMYGILDYSDEPLVSSDYNTNSHSAIIDGLTTM
HHHHEECCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
VMEDRKVKVLAWYDNEWGYSCRVVDLIRHVAARMKHPSAV
HCCCCEEEEEEEECCCCCCEEHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKVKVAINGFGRIGRMVFRKAMEDDQIQITAINASYPPETLAHLIKYDTIHGKYDQEVET
CEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCC
SDDSLIVNGKHIMLFNRRDPRELPWKECGIDIVVEATGKFNSKEKAMSHIEAGAKKVILT
CCCEEEEECCEEEEEECCCCCCCCHHHCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEE
APGKNEDVTIVMGVNEEQFNPDEHVIISNASCTTNCLAPVVKVLDQEFGIESGLMTTVHA
CCCCCCCEEEEEECCHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEE
YTNDQKNIDNPHKDLRRARACGESIIPTSTGAAKALSLVLPHLKGKLHGLALRVPVPNVS
ECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCC
LVDLVCDMKTDVSAEQVNAAFQRAAKTSMYGILDYSDEPLVSSDYNTNSHSAIIDGLTTM
HHHHEECCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
VMEDRKVKVLAWYDNEWGYSCRVVDLIRHVAARMKHPSAV
HCCCCEEEEEEEECCCCCCEEHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10799476 [H]