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The map label for this gene is ysbA [H]

Identifier: 154687023

GI number: 154687023

Start: 2717870

End: 2718307

Strand: Reverse

Name: ysbA [H]

Synonym: RBAM_025950

Alternate gene names: 154687023

Gene position: 2718307-2717870 (Counterclockwise)

Preceding gene: 154687024

Following gene: 154687022

Centisome position: 69.37

GC content: 45.66

Gene sequence:

>438_bases
ATGAGTGCGAAAAAAGTGTACGGATTTCTGACACAAGCATTTATTTTTGCCGTAATTATGCTCATATCTAATGGGATTGC
AGCGATTGTCCCCATTCCTATACCCGCTTCCGTAGTAGGTTTGGTGTTATTATTTGTCCTCTTATGCCTGAAAGTGATTA
AGCTTGAACAAGTAGAAACGCTGGGAACATCATTAACGTCACTGATCGGATTTTTATTTGTCCCGTCGGGCATCTCCGTG
ATGAATTCACTTGGCGTCATGCAGCAGTACGGCGTGCAGATCGCACTCGTCATCTTACTCGCCACCATCATTCTGTTAGG
GGCCACGGGCCTTTTTTCTCAGCTGATCTTGTCTGTCAGCCAAAAACGTCAGAAGGCAGCCCCTGAAAAACAAACGGTGC
GCCGTTCCAATCAGGAAAAAGAACTTGTGCAGCATTAG

Upstream 100 bases:

>100_bases
TTGCATTTCAGAATGAATATTCAGCCGTTTGTTATGAAAGCGCTTTAAAAGGCGATTTCTCTTTTATAATGGACCTAACA
AAGAGAAAGAGGTGAAGAAA

Downstream 100 bases:

>100_bases
GAGGGAAATCGGATGAGTCCATATTTCGGTATTGTCGTTTCACTTGCGGCCTTTGGCATCGGCACGTATTTATTTAAAAA
AACGAGAGGCTTTTTCCTCT

Product: murein hydrolase regulator LrgA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MSAKKVYGFLTQAFIFAVIMLISNGIAAIVPIPIPASVVGLVLLFVLLCLKVIKLEQVETLGTSLTSLIGFLFVPSGISV
MNSLGVMQQYGVQIALVILLATIILLGATGLFSQLILSVSQKRQKAAPEKQTVRRSNQEKELVQH

Sequences:

>Translated_145_residues
MSAKKVYGFLTQAFIFAVIMLISNGIAAIVPIPIPASVVGLVLLFVLLCLKVIKLEQVETLGTSLTSLIGFLFVPSGISV
MNSLGVMQQYGVQIALVILLATIILLGATGLFSQLILSVSQKRQKAAPEKQTVRRSNQEKELVQH
>Mature_144_residues
SAKKVYGFLTQAFIFAVIMLISNGIAAIVPIPIPASVVGLVLLFVLLCLKVIKLEQVETLGTSLTSLIGFLFVPSGISVM
NSLGVMQQYGVQIALVILLATIILLGATGLFSQLILSVSQKRQKAAPEKQTVRRSNQEKELVQH

Specific function: Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. LrgA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 15607; Mature: 15476

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKKVYGFLTQAFIFAVIMLISNGIAAIVPIPIPASVVGLVLLFVLLCLKVIKLEQVET
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGTSLTSLIGFLFVPSGISVMNSLGVMQQYGVQIALVILLATIILLGATGLFSQLILSVS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QKRQKAAPEKQTVRRSNQEKELVQH
HHHHHCCCHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
SAKKVYGFLTQAFIFAVIMLISNGIAAIVPIPIPASVVGLVLLFVLLCLKVIKLEQVET
CHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGTSLTSLIGFLFVPSGISVMNSLGVMQQYGVQIALVILLATIILLGATGLFSQLILSVS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QKRQKAAPEKQTVRRSNQEKELVQH
HHHHHCCCHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]