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The map label for this gene is etfA [H]

Identifier: 154686986

GI number: 154686986

Start: 2678622

End: 2679599

Strand: Reverse

Name: etfA [H]

Synonym: RBAM_025580

Alternate gene names: 154686986

Gene position: 2679599-2678622 (Counterclockwise)

Preceding gene: 154686987

Following gene: 154686985

Centisome position: 68.38

GC content: 49.9

Gene sequence:

>978_bases
ATGGGAAAAAAAGTGATCGTACTCGGAGAAATTCGTGACGGCGCCTTACGGAACGTCACCTTTGAAGCCATAGCCGCAGG
CAAAACCATTTCCGGCGGAGGAAATGTCATCGGCGTGCTGATGGGAAAAGGCGCAGCTGATGCAGCACCAGAACTCATTC
AGTACGGCGCCGACAAAGTATTTACGGCCGATTCGCCGGGGCTTTCTCAGTATACGGCGGACGGATATGCCGCGGTTCTC
GGGGATTTGATCGAAAATGAAAAGCCTGATGCGGTTATTTTCGGCCACACTTCTATGGGAAAAGATTTGTCACCTAAGCT
TGCGGCCCGGTTTGAAACGGGGCTGATTTCAGACAGCACGGATGTAAGCGTTACCGGAGACAACATCGTTTTTACAAGAC
CGATCTATTCCGGCAAAGCCTTTGAACAGGTGATTTCAACCGATCCGTTCATTTTGGCGACAATTCGTCCGAATAATATT
CAGGCATTAGAAAAAGACGCGAACCGGACGGGTGATATTGAAGAGCTTGCGGCGCCGCCGGCAGATTTGCGGACGGTCAT
TGAAGAAGTAGTCAAAAAAACGGCAGACGGCGTGGATTTATCAGAAGCGAAAATTATCGTAGCAGGCGGCCGCGGTGTAA
AAAGCAAAGATGGATTTGAACCGTTAAAAGAACTTGCCGAGGTGCTCGGAGCAGCGGTGGGCGCTTCACGCGGCGCGTGT
GACGCGGACTATTGCGATTATTCTCTTCAAATCGGCCAGACGGGAAAAGTCGTCACGCCGGATTTGTATATCGCCTGCGG
AATTTCCGGAGCGATTCAGCACTTGGCGGGCATGTCAAACAGTAAGGTCATCGTTGCCATTAACAAAGACCCGGAAGCGG
AAATATTTAAAATAGCGGACTACGGAATTGTCGGCGATTTGTTCGAAGTGGTTCCGCTTCTGACGCAGGAATTTAAAAAT
GCCAATATTCATTCATAA

Upstream 100 bases:

>100_bases
GAAGGAGAAGCCGCTGAGCAGGCGAAAGAGCTTGTGTCACTGCTGAGAAAAGAAGCCAAAGTCGTATAAACCGATATTAA
AGAAACTGGGGGATGTCAGA

Downstream 100 bases:

>100_bases
TCATAAACCCTCTGGCTTATTTGTCAGAGGGTTTTAATTTGTGTTAATTGGTTCGTACAAATTAAAGGTTGATAAAATAA
GAGATTGACATGTACGAACC

Product: EtfA

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MGKKVIVLGEIRDGALRNVTFEAIAAGKTISGGGNVIGVLMGKGAADAAPELIQYGADKVFTADSPGLSQYTADGYAAVL
GDLIENEKPDAVIFGHTSMGKDLSPKLAARFETGLISDSTDVSVTGDNIVFTRPIYSGKAFEQVISTDPFILATIRPNNI
QALEKDANRTGDIEELAAPPADLRTVIEEVVKKTADGVDLSEAKIIVAGGRGVKSKDGFEPLKELAEVLGAAVGASRGAC
DADYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEAEIFKIADYGIVGDLFEVVPLLTQEFKN
ANIHS

Sequences:

>Translated_325_residues
MGKKVIVLGEIRDGALRNVTFEAIAAGKTISGGGNVIGVLMGKGAADAAPELIQYGADKVFTADSPGLSQYTADGYAAVL
GDLIENEKPDAVIFGHTSMGKDLSPKLAARFETGLISDSTDVSVTGDNIVFTRPIYSGKAFEQVISTDPFILATIRPNNI
QALEKDANRTGDIEELAAPPADLRTVIEEVVKKTADGVDLSEAKIIVAGGRGVKSKDGFEPLKELAEVLGAAVGASRGAC
DADYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEAEIFKIADYGIVGDLFEVVPLLTQEFKN
ANIHS
>Mature_324_residues
GKKVIVLGEIRDGALRNVTFEAIAAGKTISGGGNVIGVLMGKGAADAAPELIQYGADKVFTADSPGLSQYTADGYAAVLG
DLIENEKPDAVIFGHTSMGKDLSPKLAARFETGLISDSTDVSVTGDNIVFTRPIYSGKAFEQVISTDPFILATIRPNNIQ
ALEKDANRTGDIEELAAPPADLRTVIEEVVKKTADGVDLSEAKIIVAGGRGVKSKDGFEPLKELAEVLGAAVGASRGACD
ADYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEAEIFKIADYGIVGDLFEVVPLLTQEFKNA
NIHS

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=327, Percent_Identity=37.0030581039755, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI189181759, Length=226, Percent_Identity=44.6902654867257, Blast_Score=181, Evalue=6e-46,
Organism=Escherichia coli, GI1787990, Length=273, Percent_Identity=33.3333333333333, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1786226, Length=276, Percent_Identity=35.1449275362319, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI87082157, Length=256, Percent_Identity=31.25, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17506929, Length=315, Percent_Identity=40.6349206349206, Blast_Score=200, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6325261, Length=228, Percent_Identity=42.1052631578947, Blast_Score=175, Evalue=8e-45,
Organism=Drosophila melanogaster, GI17136898, Length=317, Percent_Identity=41.0094637223975, Blast_Score=205, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24652801, Length=317, Percent_Identity=41.0094637223975, Blast_Score=205, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 34017; Mature: 33886

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKKVIVLGEIRDGALRNVTFEAIAAGKTISGGGNVIGVLMGKGAADAAPELIQYGADKV
CCCEEEEEECCCCCCHHCCCHHHHCCCCEECCCCCEEEEEECCCCCHHHHHHHHCCCCEE
FTADSPGLSQYTADGYAAVLGDLIENEKPDAVIFGHTSMGKDLSPKLAARFETGLISDST
EECCCCCCCHHCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCC
DVSVTGDNIVFTRPIYSGKAFEQVISTDPFILATIRPNNIQALEKDANRTGDIEELAAPP
CEEEECCCEEEECCCCCCHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCCCHHHHCCCC
ADLRTVIEEVVKKTADGVDLSEAKIIVAGGRGVKSKDGFEPLKELAEVLGAAVGASRGAC
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
DADYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEAEIFKIAD
CCCCCCCEEEECCCCCEECCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEC
YGIVGDLFEVVPLLTQEFKNANIHS
CCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GKKVIVLGEIRDGALRNVTFEAIAAGKTISGGGNVIGVLMGKGAADAAPELIQYGADKV
CCEEEEEECCCCCCHHCCCHHHHCCCCEECCCCCEEEEEECCCCCHHHHHHHHCCCCEE
FTADSPGLSQYTADGYAAVLGDLIENEKPDAVIFGHTSMGKDLSPKLAARFETGLISDST
EECCCCCCCHHCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCC
DVSVTGDNIVFTRPIYSGKAFEQVISTDPFILATIRPNNIQALEKDANRTGDIEELAAPP
CEEEECCCEEEECCCCCCHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCCCHHHHCCCC
ADLRTVIEEVVKKTADGVDLSEAKIIVAGGRGVKSKDGFEPLKELAEVLGAAVGASRGAC
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
DADYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEAEIFKIAD
CCCCCCCEEEECCCCCEECCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEC
YGIVGDLFEVVPLLTQEFKNANIHS
CCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]