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The map label for this gene is ruvA

Identifier: 154686915

GI number: 154686915

Start: 2606746

End: 2607351

Strand: Reverse

Name: ruvA

Synonym: RBAM_024850

Alternate gene names: 154686915

Gene position: 2607351-2606746 (Counterclockwise)

Preceding gene: 154686916

Following gene: 154686914

Centisome position: 66.54

GC content: 45.54

Gene sequence:

>606_bases
GTGATTGAATTCGTGAAGGGGACGATTGATTATGTATCTCCCCAATACATCGTGATTGAAAACGGCGGAATCGGCTATCA
GGTCTTCACTCCGAATCCGTTTATTTATAAGGTAAGCAATCAAGAGACCATTTTTACGTATCATCATATAAAAGAAGATG
CCTTTTCTTTGTACGGTTTTTCAACCCGGGAAGAAAAAGCGCTTTTCACAAAGCTGCTGAACGTCACCGGCATCGGGCCG
AAAGGGGCGCTCGCCATCCTCGGTTCCGGTGATCCCGGAGCCGTCATCGAAGCGATCGAACAGGAAGATGAAGCCTTTTT
GGTGAAATTTCCGGGTGTGGGCAAAAAAACGGCGCGGCAGATTATTCTTGATTTGAAAGGCAAACTGGCCGACGTCGTGC
CTGAAATGATTGACAACCTGTTCAATCATGAAGCGCGCATTGAAAAACAAGAGGCTGAAACGGCGCTTGACGAGGCGCTT
GAAGCGCTCCGGGTTCTCGGCTACGCCGAAAAAGAAATTAAAAAAGTGCTTCCTCACTTAAAAGAGGAAACGGCGCTTTC
AACAGATCAATATGTGAAAAAAGCATTGCAAAAATTATTAAAGTAA

Upstream 100 bases:

>100_bases
TTCTGAATGGAAGGTGTCAAAGCGAACATACGTTAACTTTTCTATAAGACTTTGGCTGTTTTTGTGTTACAATGATAAGC
AGTCAAAGAGGTGAATAGGT

Downstream 100 bases:

>100_bases
GGTGATGTTCATGGATGAACGGCTCGTTTCAAGTGAAGCAGACAGCCATGAATCAATAATCGAGCAAAGCCTCAGGCCGC
AGAATCTCGCCCAGTATATC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MIEFVKGTIDYVSPQYIVIENGGIGYQVFTPNPFIYKVSNQETIFTYHHIKEDAFSLYGFSTREEKALFTKLLNVTGIGP
KGALAILGSGDPGAVIEAIEQEDEAFLVKFPGVGKKTARQIILDLKGKLADVVPEMIDNLFNHEARIEKQEAETALDEAL
EALRVLGYAEKEIKKVLPHLKEETALSTDQYVKKALQKLLK

Sequences:

>Translated_201_residues
MIEFVKGTIDYVSPQYIVIENGGIGYQVFTPNPFIYKVSNQETIFTYHHIKEDAFSLYGFSTREEKALFTKLLNVTGIGP
KGALAILGSGDPGAVIEAIEQEDEAFLVKFPGVGKKTARQIILDLKGKLADVVPEMIDNLFNHEARIEKQEAETALDEAL
EALRVLGYAEKEIKKVLPHLKEETALSTDQYVKKALQKLLK
>Mature_201_residues
MIEFVKGTIDYVSPQYIVIENGGIGYQVFTPNPFIYKVSNQETIFTYHHIKEDAFSLYGFSTREEKALFTKLLNVTGIGP
KGALAILGSGDPGAVIEAIEQEDEAFLVKFPGVGKKTARQIILDLKGKLADVVPEMIDNLFNHEARIEKQEAETALDEAL
EALRVLGYAEKEIKKVLPHLKEETALSTDQYVKKALQKLLK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=207, Percent_Identity=34.7826086956522, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_BACA2 (A7Z769)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001422076.1
- ProteinModelPortal:   A7Z769
- SMR:   A7Z769
- STRING:   A7Z769
- EnsemblBacteria:   EBBACT00000004414
- GeneID:   5462894
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_024850
- eggNOG:   COG0632
- GeneTree:   EBGT00050000000364
- HOGENOM:   HBG635309
- OMA:   LFGFAQK
- ProtClustDB:   PRK00116
- BioCyc:   BAMY326423:RBAM_024850-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22415; Mature: 22415

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEFVKGTIDYVSPQYIVIENGGIGYQVFTPNPFIYKVSNQETIFTYHHIKEDAFSLYGF
CCEECCCHHHHCCCCEEEEECCCEEEEEECCCCEEEEECCCCEEEEEHHHHHHHHHHCCC
STREEKALFTKLLNVTGIGPKGALAILGSGDPGAVIEAIEQEDEAFLVKFPGVGKKTARQ
CCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEECCCCCHHHHHH
IILDLKGKLADVVPEMIDNLFNHEARIEKQEAETALDEALEALRVLGYAEKEIKKVLPHL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KEETALSTDQYVKKALQKLLK
HHHHCCCHHHHHHHHHHHHHC
>Mature Secondary Structure
MIEFVKGTIDYVSPQYIVIENGGIGYQVFTPNPFIYKVSNQETIFTYHHIKEDAFSLYGF
CCEECCCHHHHCCCCEEEEECCCEEEEEECCCCEEEEECCCCEEEEEHHHHHHHHHHCCC
STREEKALFTKLLNVTGIGPKGALAILGSGDPGAVIEAIEQEDEAFLVKFPGVGKKTARQ
CCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEECCCCCHHHHHH
IILDLKGKLADVVPEMIDNLFNHEARIEKQEAETALDEALEALRVLGYAEKEIKKVLPHL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KEETALSTDQYVKKALQKLLK
HHHHCCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA