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The map label for this gene is ruvB

Identifier: 154686914

GI number: 154686914

Start: 2605731

End: 2606735

Strand: Reverse

Name: ruvB

Synonym: RBAM_024840

Alternate gene names: 154686914

Gene position: 2606735-2605731 (Counterclockwise)

Preceding gene: 154686915

Following gene: 154686913

Centisome position: 66.52

GC content: 54.63

Gene sequence:

>1005_bases
ATGGATGAACGGCTCGTTTCAAGTGAAGCAGACAGCCATGAATCAATAATCGAGCAAAGCCTCAGGCCGCAGAATCTCGC
CCAGTATATCGGCCAAAAGAAGGTGAAAGAAAATCTGCGCGTGTTTATCGATGCGGCGAAAATGAGGCAGGAAACGCTGG
ACCACGTTCTTTTATACGGGCCTCCGGGTCTCGGGAAAACAACGCTTGCGTCTATCGTGGCCAATGAGATGGGTGTGGAG
ATGCGGACGACATCAGGTCCCGCCATCGAAAGACCGGGAGATTTGGCAGCCATTTTGACGGCGCTCGAACCAGGGGATGT
GCTGTTTATAGACGAAATTCACAGGCTGAACCGCTCAATTGAGGAAGTGCTGTACCCGGCGATGGAGGATTTCTGCCTTG
ATATCGTCATTGGAAAAGGCCCGTCCGCCCGCTCCGTCCGTCTCGACCTTCCCCCTTTTACGCTTGTAGGAGCAACGACA
AGGGTCGGATTATTGACCGCACCGCTCAGAGACCGGTTCGGGGTGCTGTCGCGCCTTGAATACTATACGCAGGAAGAGCT
GACAGATATCGTGTCAAGAACGGCTGACGTTTTTGAAGTGGATATCGAAAAAGCACCGGCTCTGGAAATCGCCAGACGGT
CAAGGGGAACGCCGCGGGTTGCAAACCGGCTTCTCAGAAGGGTGAGAGATTTTGCCCAGGTGCTCGGCGACAGCCGCATC
ACGGAAGAAATCGCTCACGACGCGCTCGAACGTCTTCAAGTCGATGCGCTCGGCCTTGACCATATCGACCATAAGCTGCT
GATGGGCATGATCGAAAAATTCAGCGGCGGTCCCGTCGGCCTTGATACGATTTCCGCGACAATCGGCGAAGAACCGCATA
CAATAGAGGATGTGTACGAACCGTATCTGCTGCAGATCGGATTTCTTCAGAGGACGCCGAGGGGACGGGTCGTGACTCCG
GCTGTGTATGAACATTTTCGATTGGAGGCGCCCGCCCGTGACTGA

Upstream 100 bases:

>100_bases
ATTAAAAAAGTGCTTCCTCACTTAAAAGAGGAAACGGCGCTTTCAACAGATCAATATGTGAAAAAAGCATTGCAAAAATT
ATTAAAGTAAGGTGATGTTC

Downstream 100 bases:

>100_bases
CTTTCCGAAGGTTCTCATGGTTCTCGGTGCCGTTTTGCTTATTGTCGGCGCAGTCTGGCACTTTGTCGGAAGGCTGCCCG
GAGATATTTTCGTTAAGAAG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MDERLVSSEADSHESIIEQSLRPQNLAQYIGQKKVKENLRVFIDAAKMRQETLDHVLLYGPPGLGKTTLASIVANEMGVE
MRTTSGPAIERPGDLAAILTALEPGDVLFIDEIHRLNRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATT
RVGLLTAPLRDRFGVLSRLEYYTQEELTDIVSRTADVFEVDIEKAPALEIARRSRGTPRVANRLLRRVRDFAQVLGDSRI
TEEIAHDALERLQVDALGLDHIDHKLLMGMIEKFSGGPVGLDTISATIGEEPHTIEDVYEPYLLQIGFLQRTPRGRVVTP
AVYEHFRLEAPARD

Sequences:

>Translated_334_residues
MDERLVSSEADSHESIIEQSLRPQNLAQYIGQKKVKENLRVFIDAAKMRQETLDHVLLYGPPGLGKTTLASIVANEMGVE
MRTTSGPAIERPGDLAAILTALEPGDVLFIDEIHRLNRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATT
RVGLLTAPLRDRFGVLSRLEYYTQEELTDIVSRTADVFEVDIEKAPALEIARRSRGTPRVANRLLRRVRDFAQVLGDSRI
TEEIAHDALERLQVDALGLDHIDHKLLMGMIEKFSGGPVGLDTISATIGEEPHTIEDVYEPYLLQIGFLQRTPRGRVVTP
AVYEHFRLEAPARD
>Mature_334_residues
MDERLVSSEADSHESIIEQSLRPQNLAQYIGQKKVKENLRVFIDAAKMRQETLDHVLLYGPPGLGKTTLASIVANEMGVE
MRTTSGPAIERPGDLAAILTALEPGDVLFIDEIHRLNRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATT
RVGLLTAPLRDRFGVLSRLEYYTQEELTDIVSRTADVFEVDIEKAPALEIARRSRGTPRVANRLLRRVRDFAQVLGDSRI
TEEIAHDALERLQVDALGLDHIDHKLLMGMIEKFSGGPVGLDTISATIGEEPHTIEDVYEPYLLQIGFLQRTPRGRVVTP
AVYEHFRLEAPARD

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=329, Percent_Identity=60.4863221884498, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1787119, Length=125, Percent_Identity=34.4, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_BACA2 (A7Z768)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001422075.1
- ProteinModelPortal:   A7Z768
- SMR:   A7Z768
- STRING:   A7Z768
- EnsemblBacteria:   EBBACT00000007210
- GeneID:   5462893
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_024840
- eggNOG:   COG2255
- GeneTree:   EBGT00050000000363
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   BAMY326423:RBAM_024840-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37225; Mature: 37225

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDERLVSSEADSHESIIEQSLRPQNLAQYIGQKKVKENLRVFIDAAKMRQETLDHVLLYG
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
PPGLGKTTLASIVANEMGVEMRTTSGPAIERPGDLAAILTALEPGDVLFIDEIHRLNRSI
CCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHH
EEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRVGLLTAPLRDRFGVLSRLE
HHHHHHHHHHHHEEEEECCCCCCCEEEECCCCEEEECCHHHHHHEECCHHHHHHHHHHHH
YYTQEELTDIVSRTADVFEVDIEKAPALEIARRSRGTPRVANRLLRRVRDFAQVLGDSRI
HHHHHHHHHHHHCCHHHHEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHH
TEEIAHDALERLQVDALGLDHIDHKLLMGMIEKFSGGPVGLDTISATIGEEPHTIEDVYE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHH
PYLLQIGFLQRTPRGRVVTPAVYEHFRLEAPARD
HHHHHHHHHHCCCCCCEECHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDERLVSSEADSHESIIEQSLRPQNLAQYIGQKKVKENLRVFIDAAKMRQETLDHVLLYG
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
PPGLGKTTLASIVANEMGVEMRTTSGPAIERPGDLAAILTALEPGDVLFIDEIHRLNRSI
CCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHH
EEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRVGLLTAPLRDRFGVLSRLE
HHHHHHHHHHHHEEEEECCCCCCCEEEECCCCEEEECCHHHHHHEECCHHHHHHHHHHHH
YYTQEELTDIVSRTADVFEVDIEKAPALEIARRSRGTPRVANRLLRRVRDFAQVLGDSRI
HHHHHHHHHHHHCCHHHHEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHH
TEEIAHDALERLQVDALGLDHIDHKLLMGMIEKFSGGPVGLDTISATIGEEPHTIEDVYE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHH
PYLLQIGFLQRTPRGRVVTPAVYEHFRLEAPARD
HHHHHHHHHHCCCCCCEECHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA