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The map label for this gene is secDF [H]

Identifier: 154686906

GI number: 154686906

Start: 2597527

End: 2599746

Strand: Reverse

Name: secDF [H]

Synonym: RBAM_024760

Alternate gene names: 154686906

Gene position: 2599746-2597527 (Counterclockwise)

Preceding gene: 154686907

Following gene: 154686905

Centisome position: 66.34

GC content: 46.17

Gene sequence:

>2220_bases
ATGAAAAAAGGACGCTTGATTGCGTTTTTCCTGATCGTATTATTGATCGGCACAGGGCTGGGGTATTTTACAAAACCGGC
TGCCAATAATATTACGTTAGGATTGGATTTACGCGGCGGGTTTGAAGTTCTGTACGATGTGCAGCCCGTCAAAAAAGGCG
ATAAAATCACAAAAGACGTGCTCGTCAGCACGGTGCAGGCGCTGAACCGCCGGGCTAACGTTCTCGGCGTAAGCGAGCCG
AACATTCAGATTGAAGGAAATAACCGCATCCGCGTACAGCTGGCGGGCGTCACGAATCAGAACAGGGCGCGCGAAATTCT
GTCAACGGAAGCGCAGCTCTCGTTCAGGGATACGAATGATAAAGAGCTGTTAAACGGCTCTGATCTCGTGGAAAACGGCG
CGAAGCAAACCTTTGATCCGACGACGAACGAACCGATTGTCAGCGTTAAGCTGAAGGATGCGGATAAGTTCGGCGAAGTG
ACGAAAAAAGTCAAGAAAATGGCGCCTAATAATCAGCTTGTGATCTGGCTTGATTACCAAAAAGGCGATTCATTTAAAAA
AGAAGTCGGCAAAAAACATCCGAAATATGTATCCGCTCCGAATGTGAGCCAGGAATTAAACACGAAGGATGTCACAATTG
AAGGCCAGTTTACCGTTCAAAAAGCGAAGGATTTGGCCAATATTTTAAACGCGGGCGCGCTGCCTGTGAAACTGACCGAA
AAATACTCTACTTCAGTAGGGGCGCAATTCGGACAGCAGGCTTTGCATGATACGGTAGAGGCCGGCATCATCGGTATTGC
AATTGTTTTCTTATTTATGCTGCTTTATTACAGACTGCCTGGACTCATAGCGGTAATTACGCTTTCTGTATACGTATATA
TTACGCTTCAAGTGTTTGACTGGATGCAGGCGGTGCTGACGCTTCCGGGTATTGCGGCGCTCATTTTGGGTGTCGGGATG
GCGGTTGACGCCAACATCATCACCTATGAACGGATAAAAGAAGAACTGAAACTCGGCAAATCCGTCCGCTCAGCTTTCCG
TTCAGGGAACAGACGGTCATTCGCGACGATTTTCGATGCGAACATTACAACGATCATCGCAGCGGTCGTGCTCTTTATTT
TCGGGACAAGCTCTGTAAAAGGGTTTGCGACGATGCTGATTCTGTCAATTCTGACAAGCTTTATTACAGCTGTCTTCCTT
TCAAGATTCCTGCTCGCCCTTCTTGTGGAAAGCAGATGGCTTGACCGGAAAAAAAGCTGGTTCGGCGTCAAGAAAAAACA
CATTATGGATATTCAGAAGACCGACGAAAATACTGAACCGCATACGGCATTCCAAAAATGGGATTTCACGAGCAAGCGAA
AATATTTCTTTATTTTCTCAAGCGCTGTAACCATTGCGGGGATTATCATCTTGCTGGTCTTTAAACTCAACCTGGGAATC
GATTTTGCAAGCGGCGCGCGGATTGACGTGCAGAGCAATCATTCTTTGACGGCACATCAGGTTGAAAAAGATTTTGATTC
TCTCGGCATGGAACCGGAAAACATCGTGCTTTCTGGTAAAGAGAACCATGTTGCCGCGGCCCGGTTTGTCGGAGAGCCAT
CTAAAGAAAAAATCGCTGAAATCAAAACGTACTTTAAGGACAAATACGGGTCTGAACCAAACGTCAGCACGGTATCGCCG
ACAGTCGGAAAAGAACTGGCCCGTAATGCTTTATATGCTGTCGCCATTGCATCAATCGGCATCATTATTTACGTGTCAAT
CCGCTTCGAGTACAGAATGGCTGTCGCCGCAATTGTATCCCTGCTGTATGACGCTTTCTTTATCATCGCGTTTTTCAGCA
TTACAAGGCTGGAGGTCGATGTCACCTTTATCGCCGCTATTCTCACCATAATCGGTTACTCGATAAATGATACGATCGTT
ACATTTGACCGGATACGCGAGCAGATGAAAAAACGTAAGCCGAAGTCATTTGCCGATCTGGAATATATCGTGAATCTGAG
CTTGCAGCAAACCTTTACACGTTCGATCAATACGGTCTTGACTGTTGTGATTGTTGTCGTCGTGCTGCTCATTTTGGGCT
CATCGTCAATTACAAACTTCTCCGTCGCTTTATTGGTCGGTTTATTGACGGGCGTTTATTCCTCTCTTTACATCGCCGCA
CAGCTGTGGCTTGTATGGAAAGGTAAAGAATTTAAAGGGAAAAAATCAATCGAAGAGTAA

Upstream 100 bases:

>100_bases
TAAGTCGTCTAATTGGCTGGAAAGCGATGAGGGTCAGGAAGCTTTAGATGAACTGCTGAGATAATGATTTGACGGCATAG
GTTTAAGGAGGAAATACATA

Downstream 100 bases:

>100_bases
AATGGGAACAGGCTGTCTTCCGGAAGGCAGCCTGTTTTTTTAGGCCGCATTGAACTTAAAACCTGCATTTGCTATAATGA
CATACGCTTACATAATCAAT

Product: bifunctional preprotein translocase subunit SecD/SecF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 739; Mature: 739

Protein sequence:

>739_residues
MKKGRLIAFFLIVLLIGTGLGYFTKPAANNITLGLDLRGGFEVLYDVQPVKKGDKITKDVLVSTVQALNRRANVLGVSEP
NIQIEGNNRIRVQLAGVTNQNRAREILSTEAQLSFRDTNDKELLNGSDLVENGAKQTFDPTTNEPIVSVKLKDADKFGEV
TKKVKKMAPNNQLVIWLDYQKGDSFKKEVGKKHPKYVSAPNVSQELNTKDVTIEGQFTVQKAKDLANILNAGALPVKLTE
KYSTSVGAQFGQQALHDTVEAGIIGIAIVFLFMLLYYRLPGLIAVITLSVYVYITLQVFDWMQAVLTLPGIAALILGVGM
AVDANIITYERIKEELKLGKSVRSAFRSGNRRSFATIFDANITTIIAAVVLFIFGTSSVKGFATMLILSILTSFITAVFL
SRFLLALLVESRWLDRKKSWFGVKKKHIMDIQKTDENTEPHTAFQKWDFTSKRKYFFIFSSAVTIAGIIILLVFKLNLGI
DFASGARIDVQSNHSLTAHQVEKDFDSLGMEPENIVLSGKENHVAAARFVGEPSKEKIAEIKTYFKDKYGSEPNVSTVSP
TVGKELARNALYAVAIASIGIIIYVSIRFEYRMAVAAIVSLLYDAFFIIAFFSITRLEVDVTFIAAILTIIGYSINDTIV
TFDRIREQMKKRKPKSFADLEYIVNLSLQQTFTRSINTVLTVVIVVVVLLILGSSSITNFSVALLVGLLTGVYSSLYIAA
QLWLVWKGKEFKGKKSIEE

Sequences:

>Translated_739_residues
MKKGRLIAFFLIVLLIGTGLGYFTKPAANNITLGLDLRGGFEVLYDVQPVKKGDKITKDVLVSTVQALNRRANVLGVSEP
NIQIEGNNRIRVQLAGVTNQNRAREILSTEAQLSFRDTNDKELLNGSDLVENGAKQTFDPTTNEPIVSVKLKDADKFGEV
TKKVKKMAPNNQLVIWLDYQKGDSFKKEVGKKHPKYVSAPNVSQELNTKDVTIEGQFTVQKAKDLANILNAGALPVKLTE
KYSTSVGAQFGQQALHDTVEAGIIGIAIVFLFMLLYYRLPGLIAVITLSVYVYITLQVFDWMQAVLTLPGIAALILGVGM
AVDANIITYERIKEELKLGKSVRSAFRSGNRRSFATIFDANITTIIAAVVLFIFGTSSVKGFATMLILSILTSFITAVFL
SRFLLALLVESRWLDRKKSWFGVKKKHIMDIQKTDENTEPHTAFQKWDFTSKRKYFFIFSSAVTIAGIIILLVFKLNLGI
DFASGARIDVQSNHSLTAHQVEKDFDSLGMEPENIVLSGKENHVAAARFVGEPSKEKIAEIKTYFKDKYGSEPNVSTVSP
TVGKELARNALYAVAIASIGIIIYVSIRFEYRMAVAAIVSLLYDAFFIIAFFSITRLEVDVTFIAAILTIIGYSINDTIV
TFDRIREQMKKRKPKSFADLEYIVNLSLQQTFTRSINTVLTVVIVVVVLLILGSSSITNFSVALLVGLLTGVYSSLYIAA
QLWLVWKGKEFKGKKSIEE
>Mature_739_residues
MKKGRLIAFFLIVLLIGTGLGYFTKPAANNITLGLDLRGGFEVLYDVQPVKKGDKITKDVLVSTVQALNRRANVLGVSEP
NIQIEGNNRIRVQLAGVTNQNRAREILSTEAQLSFRDTNDKELLNGSDLVENGAKQTFDPTTNEPIVSVKLKDADKFGEV
TKKVKKMAPNNQLVIWLDYQKGDSFKKEVGKKHPKYVSAPNVSQELNTKDVTIEGQFTVQKAKDLANILNAGALPVKLTE
KYSTSVGAQFGQQALHDTVEAGIIGIAIVFLFMLLYYRLPGLIAVITLSVYVYITLQVFDWMQAVLTLPGIAALILGVGM
AVDANIITYERIKEELKLGKSVRSAFRSGNRRSFATIFDANITTIIAAVVLFIFGTSSVKGFATMLILSILTSFITAVFL
SRFLLALLVESRWLDRKKSWFGVKKKHIMDIQKTDENTEPHTAFQKWDFTSKRKYFFIFSSAVTIAGIIILLVFKLNLGI
DFASGARIDVQSNHSLTAHQVEKDFDSLGMEPENIVLSGKENHVAAARFVGEPSKEKIAEIKTYFKDKYGSEPNVSTVSP
TVGKELARNALYAVAIASIGIIIYVSIRFEYRMAVAAIVSLLYDAFFIIAFFSITRLEVDVTFIAAILTIIGYSINDTIV
TFDRIREQMKKRKPKSFADLEYIVNLSLQQTFTRSINTVLTVVIVVVVLLILGSSSITNFSVALLVGLLTGVYSSLYIAA
QLWLVWKGKEFKGKKSIEE

Specific function: Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the secD/secF family. SecF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=376, Percent_Identity=33.2446808510638, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1786610, Length=288, Percent_Identity=28.4722222222222, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- InterPro:   IPR005665 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 81970; Mature: 81970

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGRLIAFFLIVLLIGTGLGYFTKPAANNITLGLDLRGGFEVLYDVQPVKKGDKITKDV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHH
LVSTVQALNRRANVLGVSEPNIQIEGNNRIRVQLAGVTNQNRAREILSTEAQLSFRDTND
HHHHHHHHHHCCCEEECCCCCEEEECCCEEEEEEECCCCCHHHHHHHHCCCEEEECCCCC
KELLNGSDLVENGAKQTFDPTTNEPIVSVKLKDADKFGEVTKKVKKMAPNNQLVIWLDYQ
HHHCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECC
KGDSFKKEVGKKHPKYVSAPNVSQELNTKDVTIEGQFTVQKAKDLANILNAGALPVKLTE
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHCCCCCCEEEHH
KYSTSVGAQFGQQALHDTVEAGIIGIAIVFLFMLLYYRLPGLIAVITLSVYVYITLQVFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WMQAVLTLPGIAALILGVGMAVDANIITYERIKEELKLGKSVRSAFRSGNRRSFATIFDA
HHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
NITTIIAAVVLFIFGTSSVKGFATMLILSILTSFITAVFLSRFLLALLVESRWLDRKKSW
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGVKKKHIMDIQKTDENTEPHTAFQKWDFTSKRKYFFIFSSAVTIAGIIILLVFKLNLGI
CCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCE
DFASGARIDVQSNHSLTAHQVEKDFDSLGMEPENIVLSGKENHVAAARFVGEPSKEKIAE
EECCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHCCCCCHHHHHH
IKTYFKDKYGSEPNVSTVSPTVGKELARNALYAVAIASIGIIIYVSIRFEYRMAVAAIVS
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEHHHHHHHHHHHH
LLYDAFFIIAFFSITRLEVDVTFIAAILTIIGYSINDTIVTFDRIREQMKKRKPKSFADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCCHHHH
EYIVNLSLQQTFTRSINTVLTVVIVVVVLLILGSSSITNFSVALLVGLLTGVYSSLYIAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QLWLVWKGKEFKGKKSIEE
HEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MKKGRLIAFFLIVLLIGTGLGYFTKPAANNITLGLDLRGGFEVLYDVQPVKKGDKITKDV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHH
LVSTVQALNRRANVLGVSEPNIQIEGNNRIRVQLAGVTNQNRAREILSTEAQLSFRDTND
HHHHHHHHHHCCCEEECCCCCEEEECCCEEEEEEECCCCCHHHHHHHHCCCEEEECCCCC
KELLNGSDLVENGAKQTFDPTTNEPIVSVKLKDADKFGEVTKKVKKMAPNNQLVIWLDYQ
HHHCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECC
KGDSFKKEVGKKHPKYVSAPNVSQELNTKDVTIEGQFTVQKAKDLANILNAGALPVKLTE
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHCCCCCCEEEHH
KYSTSVGAQFGQQALHDTVEAGIIGIAIVFLFMLLYYRLPGLIAVITLSVYVYITLQVFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WMQAVLTLPGIAALILGVGMAVDANIITYERIKEELKLGKSVRSAFRSGNRRSFATIFDA
HHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
NITTIIAAVVLFIFGTSSVKGFATMLILSILTSFITAVFLSRFLLALLVESRWLDRKKSW
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGVKKKHIMDIQKTDENTEPHTAFQKWDFTSKRKYFFIFSSAVTIAGIIILLVFKLNLGI
CCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCE
DFASGARIDVQSNHSLTAHQVEKDFDSLGMEPENIVLSGKENHVAAARFVGEPSKEKIAE
EECCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHCCCCCHHHHHH
IKTYFKDKYGSEPNVSTVSPTVGKELARNALYAVAIASIGIIIYVSIRFEYRMAVAAIVS
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEHHHHHHHHHHHH
LLYDAFFIIAFFSITRLEVDVTFIAAILTIIGYSINDTIVTFDRIREQMKKRKPKSFADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCCHHHH
EYIVNLSLQQTFTRSINTVLTVVIVVVVLLILGSSSITNFSVALLVGLLTGVYSSLYIAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QLWLVWKGKEFKGKKSIEE
HEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9694879; 9384377 [H]