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The map label for this gene is yrkP [H]

Identifier: 154686839

GI number: 154686839

Start: 2526449

End: 2527144

Strand: Reverse

Name: yrkP [H]

Synonym: RBAM_024090

Alternate gene names: 154686839

Gene position: 2527144-2526449 (Counterclockwise)

Preceding gene: 154686842

Following gene: 154686838

Centisome position: 64.49

GC content: 42.96

Gene sequence:

>696_bases
ATGACCCATCGAATATTAGTCGTAGAGGATGATCGGGATATTGGTGATCTTTTGGAGGAATCCCTTACGCGTTCAGGCTA
CGAGGTGTTAACAGCCAAGGATGGAAAGCGAGCATTGCAACTTGTGAATGACTCGCTTGATTTGGTTATTTTGGATATTA
TGATGCCAGGCATCTCGGGAATCGAAACCTGTCAGCACATTAGGAAAACCTCTAACGTCCCAATTCTGTTTCTGACGGCC
AGATCGAGTACACTCGATAAAACTGAGGGATTACTCGCCGGCGGCGATGATTATATGACTAAACCCTTCTCGGAAGAGGA
ACTTCACGCTAGAGTGATTGCTCAATTACGCAGATATACAATCTATCAGGAAAAGAAGGAACAGGAAGAAACATTTCTTA
TCGGGGGCAACCTGAGAGTGAGCGAAGAATTTAATGAGGTTTACAAAGAGGAGCAGCAAATCAAGTTGTCAGATCTGGAA
TATCGTATCTTGAAACTGCTGATGAGCAAACGCAACAAAATATTTTCTGCTCAAAATATATATGAGAGTGTGTGGGGACA
GCCTTACTTTTACTGTTCTAACAATACGGTGATGGTGCATATTCGGAAACTGCGCTCCAAAATTGAGGATGATCCGGCAC
GTCCGGTTTATATAAAAACTGAATGGGGAAGAGGATATCGATTTGGCACATCGTAA

Upstream 100 bases:

>100_bases
TAAGATTTACGTGGTATCTTATAACGTACGTGTTACTTATGAATGATATATAGTAAGGTCACACGAGAGATAACATCAAG
AATCATGAGGTGAAAAAGGC

Downstream 100 bases:

>100_bases
ATTCACGCTAACCAAAAAACTGGCTTTGCTGATCATGGTTGCTGCGATTGTGAGCGGTGTGATCTTTCTGACGTTGCAAA
AGATTACAGATGATCTGATC

Product: YrkP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTHRILVVEDDRDIGDLLEESLTRSGYEVLTAKDGKRALQLVNDSLDLVILDIMMPGISGIETCQHIRKTSNVPILFLTA
RSSTLDKTEGLLAGGDDYMTKPFSEEELHARVIAQLRRYTIYQEKKEQEETFLIGGNLRVSEEFNEVYKEEQQIKLSDLE
YRILKLLMSKRNKIFSAQNIYESVWGQPYFYCSNNTVMVHIRKLRSKIEDDPARPVYIKTEWGRGYRFGTS

Sequences:

>Translated_231_residues
MTHRILVVEDDRDIGDLLEESLTRSGYEVLTAKDGKRALQLVNDSLDLVILDIMMPGISGIETCQHIRKTSNVPILFLTA
RSSTLDKTEGLLAGGDDYMTKPFSEEELHARVIAQLRRYTIYQEKKEQEETFLIGGNLRVSEEFNEVYKEEQQIKLSDLE
YRILKLLMSKRNKIFSAQNIYESVWGQPYFYCSNNTVMVHIRKLRSKIEDDPARPVYIKTEWGRGYRFGTS
>Mature_230_residues
THRILVVEDDRDIGDLLEESLTRSGYEVLTAKDGKRALQLVNDSLDLVILDIMMPGISGIETCQHIRKTSNVPILFLTAR
SSTLDKTEGLLAGGDDYMTKPFSEEELHARVIAQLRRYTIYQEKKEQEETFLIGGNLRVSEEFNEVYKEEQQIKLSDLEY
RILKLLMSKRNKIFSAQNIYESVWGQPYFYCSNNTVMVHIRKLRSKIEDDPARPVYIKTEWGRGYRFGTS

Specific function: Member of the two-component regulatory system yrkQ/yrkP [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=34.7826086956522, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=34.6153846153846, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=37.1681415929204, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=33.6244541484716, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=36.283185840708, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=32.7586206896552, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=32.3008849557522, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=31.858407079646, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=36.0869565217391, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1789402, Length=232, Percent_Identity=31.8965517241379, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=32.5991189427313, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=30.8695652173913, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=28.0172413793103, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788550, Length=161, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=115, Percent_Identity=37.3913043478261, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26767; Mature: 26636

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHRILVVEDDRDIGDLLEESLTRSGYEVLTAKDGKRALQLVNDSLDLVILDIMMPGISG
CCCEEEEEECCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHEEEEEHHHCCCCH
IETCQHIRKTSNVPILFLTARSSTLDKTEGLLAGGDDYMTKPFSEEELHARVIAQLRRYT
HHHHHHHHHCCCCCEEEEECCCCCCHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
IYQEKKEQEETFLIGGNLRVSEEFNEVYKEEQQIKLSDLEYRILKLLMSKRNKIFSAQNI
HHHHHHCCCCEEEECCCEEEHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHHHHHHHHH
YESVWGQPYFYCSNNTVMVHIRKLRSKIEDDPARPVYIKTEWGRGYRFGTS
HHHHCCCEEEEECCCEEEEEHHHHHHHHCCCCCCEEEEEECCCCCEECCCC
>Mature Secondary Structure 
THRILVVEDDRDIGDLLEESLTRSGYEVLTAKDGKRALQLVNDSLDLVILDIMMPGISG
CCEEEEEECCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHEEEEEHHHCCCCH
IETCQHIRKTSNVPILFLTARSSTLDKTEGLLAGGDDYMTKPFSEEELHARVIAQLRRYT
HHHHHHHHHCCCCCEEEEECCCCCCHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
IYQEKKEQEETFLIGGNLRVSEEFNEVYKEEQQIKLSDLEYRILKLLMSKRNKIFSAQNI
HHHHHHCCCCEEEECCCEEEHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHHHHHHHHH
YESVWGQPYFYCSNNTVMVHIRKLRSKIEDDPARPVYIKTEWGRGYRFGTS
HHHHCCCEEEEECCCEEEEEHHHHHHHHCCCCCCEEEEEECCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]