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The map label for this gene is prmA

Identifier: 154686805

GI number: 154686805

Start: 2493349

End: 2494284

Strand: Reverse

Name: prmA

Synonym: RBAM_023750

Alternate gene names: 154686805

Gene position: 2494284-2493349 (Counterclockwise)

Preceding gene: 154686806

Following gene: 154686804

Centisome position: 63.65

GC content: 45.73

Gene sequence:

>936_bases
TTGAAATGGTCCGAAATCAGCATTCACACAACACATGAAGCGGTCGAACCCATCTCAAATATTTTGCATGAAGCTGGTGC
GAGCGGGGTTGTCATCGAAGATCCGCTTGATTTAATGAAAGAGCGTGAGAATGTTTACGGGGAAATCTACCAGCTCGACC
CCAATGATTACCCCGATGAGGGTGTCATTGTCAAAGCGTATCTGCCGATCAACAGTTTCCTCGGCGAAACGGTGGACGGC
ATAAAAGAGACGATTAATAATCTGCTTTTGTACGACATTGATTTGGGCAGAAACACAATCACCATTTCTGAAGTTAATGA
AGAAGAATGGGCGACAGCTTGGAAAAAGTATTATCATCCTGTGAAAATTTCTGAAAAGTTCACGATCGTTCCCACTTGGG
AAACGTACACACCTGTTCATACAGATGAACTGATTATCGAAATGGATCCGGGTATGGCATTCGGTACGGGAACGCATCCG
ACAACCGTTCTGTGCATTCAGGCGCTTGAGCGTATCGTTCAAAAAGGCGACCGTGTCATTGATGTCGGCACCGGTTCAGG
AATTTTAAGCATCGCGGCCGCCATGCTTGAGGCCGAATCGGTTCATGCGTATGACCTTGATCCGGTCGCTGTTGAAAGCG
CGCGTCTGAATGTGAAATTGAACAAAGTGAGTGATACGGCTGAAGTGAAGCAGAACAATTTGTTAGACGGCATCACGGGC
GAACATGATGTCATTGTCGCAAATATTTTGGCGGAAGTGATTCTCCGCTTTACATCACAGGCGTACGACCTGCTCAAAGA
CGGAGGCCATTTTATTACTTCAGGCATTATCGGCCAGAAAAAACAGGAAGTAAAAGAAGCGTTGGAAAAAGCCGGCTTTA
CCATCATAGAAATTCTGTCTATGGAAGATTGGGTCAGCATCATCGCGAAAAAATAA

Upstream 100 bases:

>100_bases
AAGTCAGCGGAAACCTGCCGGATGAACAAGAAATGAGTTTCTTTGACAAAGTAAAACGCGCATTTAAAGGCGAGTAATGA
TTGGATAGGAGTTGGTAGTT

Downstream 100 bases:

>100_bases
CAGTTAGTAGGTGTCACAGCGTATGCAACGATATTTTATCGAGCTCACGAAGCAGGAGATGGACGAAACTCCTGATTTTC
AAATCACGGGGGAAGACGTC

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKWSEISIHTTHEAVEPISNILHEAGASGVVIEDPLDLMKERENVYGEIYQLDPNDYPDEGVIVKAYLPINSFLGETVDG
IKETINNLLLYDIDLGRNTITISEVNEEEWATAWKKYYHPVKISEKFTIVPTWETYTPVHTDELIIEMDPGMAFGTGTHP
TTVLCIQALERIVQKGDRVIDVGTGSGILSIAAAMLEAESVHAYDLDPVAVESARLNVKLNKVSDTAEVKQNNLLDGITG
EHDVIVANILAEVILRFTSQAYDLLKDGGHFITSGIIGQKKQEVKEALEKAGFTIIEILSMEDWVSIIAKK

Sequences:

>Translated_311_residues
MKWSEISIHTTHEAVEPISNILHEAGASGVVIEDPLDLMKERENVYGEIYQLDPNDYPDEGVIVKAYLPINSFLGETVDG
IKETINNLLLYDIDLGRNTITISEVNEEEWATAWKKYYHPVKISEKFTIVPTWETYTPVHTDELIIEMDPGMAFGTGTHP
TTVLCIQALERIVQKGDRVIDVGTGSGILSIAAAMLEAESVHAYDLDPVAVESARLNVKLNKVSDTAEVKQNNLLDGITG
EHDVIVANILAEVILRFTSQAYDLLKDGGHFITSGIIGQKKQEVKEALEKAGFTIIEILSMEDWVSIIAKK
>Mature_311_residues
MKWSEISIHTTHEAVEPISNILHEAGASGVVIEDPLDLMKERENVYGEIYQLDPNDYPDEGVIVKAYLPINSFLGETVDG
IKETINNLLLYDIDLGRNTITISEVNEEEWATAWKKYYHPVKISEKFTIVPTWETYTPVHTDELIIEMDPGMAFGTGTHP
TTVLCIQALERIVQKGDRVIDVGTGSGILSIAAAMLEAESVHAYDLDPVAVESARLNVKLNKVSDTAEVKQNNLLDGITG
EHDVIVANILAEVILRFTSQAYDLLKDGGHFITSGIIGQKKQEVKEALEKAGFTIIEILSMEDWVSIIAKK

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=316, Percent_Identity=31.0126582278481, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_BACA2 (A7Z6V9)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001421966.1
- ProteinModelPortal:   A7Z6V9
- SMR:   A7Z6V9
- STRING:   A7Z6V9
- EnsemblBacteria:   EBBACT00000004934
- GeneID:   5460809
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_023750
- eggNOG:   COG2264
- GeneTree:   EBGT00050000002784
- HOGENOM:   HBG584653
- OMA:   IELNPGM
- ProtClustDB:   PRK00517
- BioCyc:   BAMY326423:RBAM_023750-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34461; Mature: 34461

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWSEISIHTTHEAVEPISNILHEAGASGVVIEDPLDLMKERENVYGEIYQLDPNDYPDE
CCCCEEEEECHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCEEEEEECCCCCCCC
GVIVKAYLPINSFLGETVDGIKETINNLLLYDIDLGRNTITISEVNEEEWATAWKKYYHP
CEEEEEEECHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEECCHHHHHHHHHHHCCC
VKISEKFTIVPTWETYTPVHTDELIIEMDPGMAFGTGTHPTTVLCIQALERIVQKGDRVI
EEECCEEEEEECCCCCCCCCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHCCCEEE
DVGTGSGILSIAAAMLEAESVHAYDLDPVAVESARLNVKLNKVSDTAEVKQNNLLDGITG
EECCCCHHHHHHHHHHHHCCCEEECCCCCEEECEEEEEEEECCCCHHHHHHCCCCCCCCC
EHDVIVANILAEVILRFTSQAYDLLKDGGHFITSGIIGQKKQEVKEALEKAGFTIIEILS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCEEEEHHH
MEDWVSIIAKK
HHHHHHHHCCC
>Mature Secondary Structure
MKWSEISIHTTHEAVEPISNILHEAGASGVVIEDPLDLMKERENVYGEIYQLDPNDYPDE
CCCCEEEEECHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCEEEEEECCCCCCCC
GVIVKAYLPINSFLGETVDGIKETINNLLLYDIDLGRNTITISEVNEEEWATAWKKYYHP
CEEEEEEECHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEECCHHHHHHHHHHHCCC
VKISEKFTIVPTWETYTPVHTDELIIEMDPGMAFGTGTHPTTVLCIQALERIVQKGDRVI
EEECCEEEEEECCCCCCCCCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHCCCEEE
DVGTGSGILSIAAAMLEAESVHAYDLDPVAVESARLNVKLNKVSDTAEVKQNNLLDGITG
EECCCCHHHHHHHHHHHHCCCEEECCCCCEEECEEEEEEEECCCCHHHHHHCCCCCCCCC
EHDVIVANILAEVILRFTSQAYDLLKDGGHFITSGIIGQKKQEVKEALEKAGFTIIEILS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCEEEEHHH
MEDWVSIIAKK
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA