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The map label for this gene is aroF

Identifier: 154686519

GI number: 154686519

Start: 2185613

End: 2186785

Strand: Reverse

Name: aroF

Synonym: RBAM_020870

Alternate gene names: 154686519

Gene position: 2186785-2185613 (Counterclockwise)

Preceding gene: 154686520

Following gene: 154686518

Centisome position: 55.81

GC content: 50.21

Gene sequence:

>1173_bases
ATGAGATACTTAACAGCCGGAGAATCACACGGTCCGCAGCTGACGACAATTATAGAAGGTGTGCCTGCGGGGCTTTATAT
AACTGAAGAAGACATTAATTTTGAGCTTGCCAGACGTCAAAAAGGGCACGGCCGCGGACGCCGCATGCAGATTGAAACGG
ACAGAGCGAAGATCACAAGCGGCGTGCGGCATGCCCGGACACTCGGTTCACCGATCGCGCTCGTTGTAGAAAATAAAGAC
TGGACTCACTGGACAAAAATCATGGGCGCCGCACCGATTACAGAAGAAGAAGAAAGTGAAATGAAACGCCAGATTTCAAG
ACCGAGACCGGGACACGCAGATTTGAACGGTGCTATTAAGTATAATCACCGTGATATGAGAAATGTGTTAGAACGATCTT
CCGCGCGTGAGACAACGGTTCGCGTGGCTGCCGGAGCCGTCGCTAAAAAGATTTTAGCTGAGCTTGGCATTAAAGTCGCC
GGACATGTCCTGCAAATCGGCAGCGTAAAAGCAGAGAAAACCGATTACACATCCATTGAGGATCTCAAACGGGTAACGGA
AGAATCACCGGTCAGATGCTACGATGAAGAAGCAGGCCGTCAAATGATGGCAGCCATTGATGAAGCGAAGGCAAACGGCG
ACTCGATCGGCGGAATCGTTGAAGTGATCGTCGAAGGTATGCCGGTCGGTGTCGGAAGCTATGTCCACTATGACCGTAAG
CTGGACAGCAAGCTCGCTGCTGCCGTTCTGTCGATTAACGCGTTTAAAGGCGTAGAGTTCGGCATCGGTTTTGAAGCGGC
CGGCAAAAACGGCAGTGAAGTTCATGATGAAATCGTATGGGATGAAGAGAAAGGCTATACACGCGCCACAAACAGGCTCG
GAGGATTAGAAGGCGGTATGACGACGGGAATGCCGATTGTCGTCCGCGGCGTTATGAAACCGATCCCTACTTTGTACAAG
CCGCTGAAAAGCGTCGACATTGAAACGAAAGAACCGTTTACAGCGAGCATTGAACGTTCAGACAGCTGTGCGGTTCCGGC
AGCAAGTGTAGTGGCTGAAGCAGCAGTGGCCTGGGAAATCGCAAATGCCGTCGTAGAACAATTCGGGCTTGACCAGATCG
ACCGAATTAAAGAAAATGTTGAAAACATGAAAAAATTATCGAGGGAATTCTGA

Upstream 100 bases:

>100_bases
CTGATACATTTTTTTATCAAAAAAGATAGAAGACATTTAATGAAAACTTGTGGTATAGTTTTACTTAAAAGCGTTAATGC
GATGAAGGGAGAAGAAAGAA

Downstream 100 bases:

>100_bases
TGAAAGAGCTTGAGGTTCGGACAGCTTCCTCCGCATATCCCGTGTATATCGGTGAAGGTATAAGGAAACAGGCCGCTGCC
CTTTTGTCTTCACTGAACAG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MRYLTAGESHGPQLTTIIEGVPAGLYITEEDINFELARRQKGHGRGRRMQIETDRAKITSGVRHARTLGSPIALVVENKD
WTHWTKIMGAAPITEEEESEMKRQISRPRPGHADLNGAIKYNHRDMRNVLERSSARETTVRVAAGAVAKKILAELGIKVA
GHVLQIGSVKAEKTDYTSIEDLKRVTEESPVRCYDEEAGRQMMAAIDEAKANGDSIGGIVEVIVEGMPVGVGSYVHYDRK
LDSKLAAAVLSINAFKGVEFGIGFEAAGKNGSEVHDEIVWDEEKGYTRATNRLGGLEGGMTTGMPIVVRGVMKPIPTLYK
PLKSVDIETKEPFTASIERSDSCAVPAASVVAEAAVAWEIANAVVEQFGLDQIDRIKENVENMKKLSREF

Sequences:

>Translated_390_residues
MRYLTAGESHGPQLTTIIEGVPAGLYITEEDINFELARRQKGHGRGRRMQIETDRAKITSGVRHARTLGSPIALVVENKD
WTHWTKIMGAAPITEEEESEMKRQISRPRPGHADLNGAIKYNHRDMRNVLERSSARETTVRVAAGAVAKKILAELGIKVA
GHVLQIGSVKAEKTDYTSIEDLKRVTEESPVRCYDEEAGRQMMAAIDEAKANGDSIGGIVEVIVEGMPVGVGSYVHYDRK
LDSKLAAAVLSINAFKGVEFGIGFEAAGKNGSEVHDEIVWDEEKGYTRATNRLGGLEGGMTTGMPIVVRGVMKPIPTLYK
PLKSVDIETKEPFTASIERSDSCAVPAASVVAEAAVAWEIANAVVEQFGLDQIDRIKENVENMKKLSREF
>Mature_390_residues
MRYLTAGESHGPQLTTIIEGVPAGLYITEEDINFELARRQKGHGRGRRMQIETDRAKITSGVRHARTLGSPIALVVENKD
WTHWTKIMGAAPITEEEESEMKRQISRPRPGHADLNGAIKYNHRDMRNVLERSSARETTVRVAAGAVAKKILAELGIKVA
GHVLQIGSVKAEKTDYTSIEDLKRVTEESPVRCYDEEAGRQMMAAIDEAKANGDSIGGIVEVIVEGMPVGVGSYVHYDRK
LDSKLAAAVLSINAFKGVEFGIGFEAAGKNGSEVHDEIVWDEEKGYTRATNRLGGLEGGMTTGMPIVVRGVMKPIPTLYK
PLKSVDIETKEPFTASIERSDSCAVPAASVVAEAAVAWEIANAVVEQFGLDQIDRIKENVENMKKLSREF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=368, Percent_Identity=36.4130434782609, Blast_Score=177, Evalue=7e-46,
Organism=Saccharomyces cerevisiae, GI6321290, Length=376, Percent_Identity=33.5106382978723, Blast_Score=187, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_BACA2 (A7Z623)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001421680.1
- ProteinModelPortal:   A7Z623
- SMR:   A7Z623
- STRING:   A7Z623
- EnsemblBacteria:   EBBACT00000005625
- GeneID:   5462033
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_020870
- eggNOG:   COG0082
- GeneTree:   EBGT00050000002373
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   BAMY326423:RBAM_020870-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42667; Mature: 42667

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLTAGESHGPQLTTIIEGVPAGLYITEEDINFELARRQKGHGRGRRMQIETDRAKITS
CCCCCCCCCCCCCHHHHHHCCCCCEEEECCCCCHHHHHHHCCCCCCCEEEEECHHHHHHH
GVRHARTLGSPIALVVENKDWTHWTKIMGAAPITEEEESEMKRQISRPRPGHADLNGAIK
HHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEE
YNHRDMRNVLERSSARETTVRVAAGAVAKKILAELGIKVAGHVLQIGSVKAEKTDYTSIE
ECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHEECCCCCCCCCCCCHH
DLKRVTEESPVRCYDEEAGRQMMAAIDEAKANGDSIGGIVEVIVEGMPVGVGSYVHYDRK
HHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
LDSKLAAAVLSINAFKGVEFGIGFEAAGKNGSEVHDEIVWDEEKGYTRATNRLGGLEGGM
HHHHHHHHHHHHHHHCCCEECCCEECCCCCCCHHHHHHCCCCCCCCHHHHHHCCCCCCCC
TTGMPIVVRGVMKPIPTLYKPLKSVDIETKEPFTASIERSDSCAVPAASVVAEAAVAWEI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHH
ANAVVEQFGLDQIDRIKENVENMKKLSREF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRYLTAGESHGPQLTTIIEGVPAGLYITEEDINFELARRQKGHGRGRRMQIETDRAKITS
CCCCCCCCCCCCCHHHHHHCCCCCEEEECCCCCHHHHHHHCCCCCCCEEEEECHHHHHHH
GVRHARTLGSPIALVVENKDWTHWTKIMGAAPITEEEESEMKRQISRPRPGHADLNGAIK
HHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEE
YNHRDMRNVLERSSARETTVRVAAGAVAKKILAELGIKVAGHVLQIGSVKAEKTDYTSIE
ECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHEECCCCCCCCCCCCHH
DLKRVTEESPVRCYDEEAGRQMMAAIDEAKANGDSIGGIVEVIVEGMPVGVGSYVHYDRK
HHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
LDSKLAAAVLSINAFKGVEFGIGFEAAGKNGSEVHDEIVWDEEKGYTRATNRLGGLEGGM
HHHHHHHHHHHHHHHCCCEECCCEECCCCCCCHHHHHHCCCCCCCCHHHHHHCCCCCCCC
TTGMPIVVRGVMKPIPTLYKPLKSVDIETKEPFTASIERSDSCAVPAASVVAEAAVAWEI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHH
ANAVVEQFGLDQIDRIKENVENMKKLSREF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA