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The map label for this gene is aroB

Identifier: 154686518

GI number: 154686518

Start: 2184525

End: 2185613

Strand: Reverse

Name: aroB

Synonym: RBAM_020860

Alternate gene names: 154686518

Gene position: 2185613-2184525 (Counterclockwise)

Preceding gene: 154686519

Following gene: 154686517

Centisome position: 55.78

GC content: 49.49

Gene sequence:

>1089_bases
ATGAAAGAGCTTGAGGTTCGGACAGCTTCCTCCGCATATCCCGTGTATATCGGTGAAGGTATAAGGAAACAGGCCGCTGC
CCTTTTGTCTTCACTGAACAGGCCGCTGACAAAGATCCTTCTCATCATCGATGCTGAAGTTGACCGGCTTTACGGTGATG
AGATGTTCCGGCTTTTAAACGAAACATGGCCCGTGAAAAAAGTGATCGTTCCAAGCGGAGAAGAAGCGAAATCTCTAAAA
GAGTATGAACGGATTCAAACGGAAGCGATCGCTTTCCATATGGACCGCTCCTCATGTATGATCGCCTTCGGAGGCGGCGT
GACGGGTGATTTGGCCGGCTTTTGCGCAGCAACTTTTATGCGCGGAATTGATTTCATTCAAATGCCGACAACACTGCTTG
CCCATGACAGCGCGGTCGGCGGCAAGGTGGCCGTCAACCATAAACTCGGAAAGAACTTAATCGGCGCGTTTTATCAGCCG
AAAGCGGTGATTTACGATACGGAGCTTCTGAAAACCCTGCCGGAACAAGAGCTGAGATCGGGCATGGCTGAAGTGATCAA
ACACGCGTTTATCGCCGATCATGCTTTTTTAGAAAAACTTCTCACGTTTGACACGTTGCAAGGACTGACAAGCGCTGAGC
TGAATGAAATGATTTATAAAGGAATTTCAATCAAATCGGCCGTCGTGCGTGAGGACGAAAAGGAAGAGGGGATAAGAGCT
TTTCTGAATTTCGGCCATACGCTCGGCCATGCCGTTGAGGCGGAATACGGCTACGGACGGATTACACATGGAGATGCGGT
CGCCCTCGGCATGCAGTTTGCCCTTTACGTGAGTGAACAGGTTGCACGTTGCAAGATGAACAGGAAAGAACTCACACAAT
GGCTGATTGGGCTCGGCTACCCGGGAAGCATCAGACAAGATATTGAAACGCCGGTTCTCTCCGCCCGGATGATGAATGAT
AAAAAAACGCGCGGAGGCATGACACAGTTCATCGTGTTAAAGGAATTAGGCGAAGCGCGGGACTGCATGCTTTCAAAAGA
TGAGCTCGAAAATTTGCTGAACAAATGGCGAATGGAGGAAACAGCATGA

Upstream 100 bases:

>100_bases
GGGAAATCGCAAATGCCGTCGTAGAACAATTCGGGCTTGACCAGATCGACCGAATTAAAGAAAATGTTGAAAACATGAAA
AAATTATCGAGGGAATTCTG

Downstream 100 bases:

>100_bases
TGATACGCGGCATTCGCGGAGCAACAACGGTGGAACAAGACACCGAACAAGAAATTTTAGAAAAAACACAGCAGCTGCTT
GAAAAAATCATTGAACAAAA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKELEVRTASSAYPVYIGEGIRKQAAALLSSLNRPLTKILLIIDAEVDRLYGDEMFRLLNETWPVKKVIVPSGEEAKSLK
EYERIQTEAIAFHMDRSSCMIAFGGGVTGDLAGFCAATFMRGIDFIQMPTTLLAHDSAVGGKVAVNHKLGKNLIGAFYQP
KAVIYDTELLKTLPEQELRSGMAEVIKHAFIADHAFLEKLLTFDTLQGLTSAELNEMIYKGISIKSAVVREDEKEEGIRA
FLNFGHTLGHAVEAEYGYGRITHGDAVALGMQFALYVSEQVARCKMNRKELTQWLIGLGYPGSIRQDIETPVLSARMMND
KKTRGGMTQFIVLKELGEARDCMLSKDELENLLNKWRMEETA

Sequences:

>Translated_362_residues
MKELEVRTASSAYPVYIGEGIRKQAAALLSSLNRPLTKILLIIDAEVDRLYGDEMFRLLNETWPVKKVIVPSGEEAKSLK
EYERIQTEAIAFHMDRSSCMIAFGGGVTGDLAGFCAATFMRGIDFIQMPTTLLAHDSAVGGKVAVNHKLGKNLIGAFYQP
KAVIYDTELLKTLPEQELRSGMAEVIKHAFIADHAFLEKLLTFDTLQGLTSAELNEMIYKGISIKSAVVREDEKEEGIRA
FLNFGHTLGHAVEAEYGYGRITHGDAVALGMQFALYVSEQVARCKMNRKELTQWLIGLGYPGSIRQDIETPVLSARMMND
KKTRGGMTQFIVLKELGEARDCMLSKDELENLLNKWRMEETA
>Mature_362_residues
MKELEVRTASSAYPVYIGEGIRKQAAALLSSLNRPLTKILLIIDAEVDRLYGDEMFRLLNETWPVKKVIVPSGEEAKSLK
EYERIQTEAIAFHMDRSSCMIAFGGGVTGDLAGFCAATFMRGIDFIQMPTTLLAHDSAVGGKVAVNHKLGKNLIGAFYQP
KAVIYDTELLKTLPEQELRSGMAEVIKHAFIADHAFLEKLLTFDTLQGLTSAELNEMIYKGISIKSAVVREDEKEEGIRA
FLNFGHTLGHAVEAEYGYGRITHGDAVALGMQFALYVSEQVARCKMNRKELTQWLIGLGYPGSIRQDIETPVLSARMMND
KKTRGGMTQFIVLKELGEARDCMLSKDELENLLNKWRMEETA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=349, Percent_Identity=40.1146131805158, Blast_Score=221, Evalue=6e-59,
Organism=Saccharomyces cerevisiae, GI6320332, Length=318, Percent_Identity=34.2767295597484, Blast_Score=162, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_BACA2 (A7Z622)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001421679.1
- ProteinModelPortal:   A7Z622
- SMR:   A7Z622
- STRING:   A7Z622
- EnsemblBacteria:   EBBACT00000007338
- GeneID:   5462032
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_020860
- eggNOG:   COG0337
- GeneTree:   EBGT00050000002325
- HOGENOM:   HBG632303
- OMA:   SEIVEIC
- ProtClustDB:   PRK00002
- BioCyc:   BAMY326423:RBAM_020860-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 40336; Mature: 40336

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELEVRTASSAYPVYIGEGIRKQAAALLSSLNRPLTKILLIIDAEVDRLYGDEMFRLLN
CCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCHHHHHHHHEECHHHHHHHHHHHHHHH
ETWPVKKVIVPSGEEAKSLKEYERIQTEAIAFHMDRSSCMIAFGGGVTGDLAGFCAATFM
HCCCCEEEECCCCHHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCCCHHHHHHHHHHHH
RGIDFIQMPTTLLAHDSAVGGKVAVNHKLGKNLIGAFYQPKAVIYDTELLKTLPEQELRS
HCCHHHHCCHHHHHCCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEHHHHHHCCHHHHHH
GMAEVIKHAFIADHAFLEKLLTFDTLQGLTSAELNEMIYKGISIKSAVVREDEKEEGIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHH
FLNFGHTLGHAVEAEYGYGRITHGDAVALGMQFALYVSEQVARCKMNRKELTQWLIGLGY
HHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
PGSIRQDIETPVLSARMMNDKKTRGGMTQFIVLKELGEARDCMLSKDELENLLNKWRMEE
CCCHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCC
TA
CC
>Mature Secondary Structure
MKELEVRTASSAYPVYIGEGIRKQAAALLSSLNRPLTKILLIIDAEVDRLYGDEMFRLLN
CCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCHHHHHHHHEECHHHHHHHHHHHHHHH
ETWPVKKVIVPSGEEAKSLKEYERIQTEAIAFHMDRSSCMIAFGGGVTGDLAGFCAATFM
HCCCCEEEECCCCHHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCCCHHHHHHHHHHHH
RGIDFIQMPTTLLAHDSAVGGKVAVNHKLGKNLIGAFYQPKAVIYDTELLKTLPEQELRS
HCCHHHHCCHHHHHCCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEHHHHHHCCHHHHHH
GMAEVIKHAFIADHAFLEKLLTFDTLQGLTSAELNEMIYKGISIKSAVVREDEKEEGIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHH
FLNFGHTLGHAVEAEYGYGRITHGDAVALGMQFALYVSEQVARCKMNRKELTQWLIGLGY
HHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
PGSIRQDIETPVLSARMMNDKKTRGGMTQFIVLKELGEARDCMLSKDELENLLNKWRMEE
CCCHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCC
TA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA