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The map label for this gene is dapB

Identifier: 154686496

GI number: 154686496

Start: 2164692

End: 2165495

Strand: Reverse

Name: dapB

Synonym: RBAM_020640

Alternate gene names: 154686496

Gene position: 2165495-2164692 (Counterclockwise)

Preceding gene: 154686497

Following gene: 154686495

Centisome position: 55.26

GC content: 50.37

Gene sequence:

>804_bases
ATGTCAAATGAAACCATTAAAGTCGTCATTGCCGGACCGAGAGGCAGAATGGGCCAGGAGGCCGTAAAACTTGCCGTCCG
CACGCCTCATTTTGAGCTTGTCGGCGCCATTGACCATACATACGATCAGCAAACATTGCGGGAAGTGATGTCAGCTGATT
CAGACGCTCTTATTTATACGGATATCCGCGCATGTTTCCAAGAAACAAAACCGGATGTGCTGATCGATTTGACAACGCCT
GAAATCGGCAAAAAACATACGAAAGCCGCTCTTGAACACGGCGTCCGCCCCGTTGTGGGAACGACCGGATTTTCTGAAGC
GGATTTAGAGGAGCTTCAAGCCTTGACTGAAGAAAAAGGAATCGGCGCCATCATCGCTCCGAACTTTGCATTGGGCGCGG
TGCTGATGATGAAGTTCTCACAAATGGCCGCCAACTATTTTGAAGATGTAGAAATCATTGAACTTCATCATGATCAAAAG
CTGGATGCCCCGAGCGGAACGGCGCTGAAAACAGCGGAAATGATCTCAAGCGTCCGTACAGAAAAGCAGCAGGGCCATCC
TGATGAAAAAGAAATTCTGCCAGGCGCCCGCGGTGCTGAATTAAACGGCATCCGCCTTCACAGCGTGCGTCTGCCGGGCC
TTATCGCCCACCAGGAAGTCATGTTCGGCATGGACGGCCAGACGCTGAAACTGCGCCATGACTCCTATAACCGGGCTTCC
TTTATGTCAGGAGTAAAGCTGTCAGTGGAGCAAGTGATGAAAATCGACCAGCTTGTATACGGACTCGAAAATATTATCGA
CTGA

Upstream 100 bases:

>100_bases
ATATTTCATTGGAGGAAGCTCATAACCGCGTCATGCATAAATTTAATACACGTGATAAAGACCGCTGGACTAGAAAAGAA
GAAGGAAAGTAGGAGAAACC

Downstream 100 bases:

>100_bases
ATCGGCAAGGGGGAGAACATCAAATGAAAATCGCTTTGATTGCTCACGATAAGAAAAAGCAGGATATGGTTCAGTTTACG
ACCGCATATAAAGATATACT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSNETIKVVIAGPRGRMGQEAVKLAVRTPHFELVGAIDHTYDQQTLREVMSADSDALIYTDIRACFQETKPDVLIDLTTP
EIGKKHTKAALEHGVRPVVGTTGFSEADLEELQALTEEKGIGAIIAPNFALGAVLMMKFSQMAANYFEDVEIIELHHDQK
LDAPSGTALKTAEMISSVRTEKQQGHPDEKEILPGARGAELNGIRLHSVRLPGLIAHQEVMFGMDGQTLKLRHDSYNRAS
FMSGVKLSVEQVMKIDQLVYGLENIID

Sequences:

>Translated_267_residues
MSNETIKVVIAGPRGRMGQEAVKLAVRTPHFELVGAIDHTYDQQTLREVMSADSDALIYTDIRACFQETKPDVLIDLTTP
EIGKKHTKAALEHGVRPVVGTTGFSEADLEELQALTEEKGIGAIIAPNFALGAVLMMKFSQMAANYFEDVEIIELHHDQK
LDAPSGTALKTAEMISSVRTEKQQGHPDEKEILPGARGAELNGIRLHSVRLPGLIAHQEVMFGMDGQTLKLRHDSYNRAS
FMSGVKLSVEQVMKIDQLVYGLENIID
>Mature_266_residues
SNETIKVVIAGPRGRMGQEAVKLAVRTPHFELVGAIDHTYDQQTLREVMSADSDALIYTDIRACFQETKPDVLIDLTTPE
IGKKHTKAALEHGVRPVVGTTGFSEADLEELQALTEEKGIGAIIAPNFALGAVLMMKFSQMAANYFEDVEIIELHHDQKL
DAPSGTALKTAEMISSVRTEKQQGHPDEKEILPGARGAELNGIRLHSVRLPGLIAHQEVMFGMDGQTLKLRHDSYNRASF
MSGVKLSVEQVMKIDQLVYGLENIID

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=285, Percent_Identity=27.3684210526316, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_BACA2 (A7Z600)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001421657.1
- ProteinModelPortal:   A7Z600
- SMR:   A7Z600
- STRING:   A7Z600
- EnsemblBacteria:   EBBACT00000006353
- GeneID:   5461680
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_020640
- eggNOG:   COG0289
- GeneTree:   EBGT00050000002586
- HOGENOM:   HBG594002
- OMA:   YNNENIE
- ProtClustDB:   PRK00048
- BioCyc:   BAMY326423:RBAM_020640-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 29375; Mature: 29244

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNETIKVVIAGPRGRMGQEAVKLAVRTPHFELVGAIDHTYDQQTLREVMSADSDALIYT
CCCCEEEEEEECCCCCCCHHHHHHHHCCCCEEEEEHHHHHCCHHHHHHHHCCCCCEEEHH
DIRACFQETKPDVLIDLTTPEIGKKHTKAALEHGVRPVVGTTGFSEADLEELQALTEEKG
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHCC
IGAIIAPNFALGAVLMMKFSQMAANYFEDVEIIELHHDQKLDAPSGTALKTAEMISSVRT
CCEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
EKQQGHPDEKEILPGARGAELNGIRLHSVRLPGLIAHQEVMFGMDGQTLKLRHDSYNRAS
HHHHCCCCHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCEEEEECCCCCHHH
FMSGVKLSVEQVMKIDQLVYGLENIID
HHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNETIKVVIAGPRGRMGQEAVKLAVRTPHFELVGAIDHTYDQQTLREVMSADSDALIYT
CCCEEEEEEECCCCCCCHHHHHHHHCCCCEEEEEHHHHHCCHHHHHHHHCCCCCEEEHH
DIRACFQETKPDVLIDLTTPEIGKKHTKAALEHGVRPVVGTTGFSEADLEELQALTEEKG
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHCC
IGAIIAPNFALGAVLMMKFSQMAANYFEDVEIIELHHDQKLDAPSGTALKTAEMISSVRT
CCEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
EKQQGHPDEKEILPGARGAELNGIRLHSVRLPGLIAHQEVMFGMDGQTLKLRHDSYNRAS
HHHHCCCCHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCEEEEECCCCCHHH
FMSGVKLSVEQVMKIDQLVYGLENIID
HHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA