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The map label for this gene is yprA [H]

Identifier: 154686469

GI number: 154686469

Start: 2139824

End: 2142070

Strand: Reverse

Name: yprA [H]

Synonym: RBAM_020370

Alternate gene names: 154686469

Gene position: 2142070-2139824 (Counterclockwise)

Preceding gene: 154686470

Following gene: 154686468

Centisome position: 54.66

GC content: 48.2

Gene sequence:

>2247_bases
ATGAAGAAAAAATCACTGAGCGAACTGATTCAGGAATTAAAAAATCATGAAAATATTGTGCATTGGCATGAAGAGGAACC
GCGGGAGGCGAAAACCATGCCGATGCCGGAGCAAGTAGATCCGAACATTCGGGCGGCTCTCGAAAAGAGGGGGATCGAGC
GGCTCTTTACACATCAATACTCCGCTTTTCAGACGGTTCAAAACGGAGAAAGCATTGTGGCTGTCACACCGACGGCCTCC
GGAAAAACACTGTGCTATAATCTTCCGGTTCTTCAGTCTATCGCGGAAGATGCCTCAAGCCGCGCGCTTTATTTATTTCC
GACAAAGGCGCTCGCGCAGGATCAAAAAAGCGAGCTGAACGAAATCATAGACGAGACGGGCATGGACATTAAAAGCTTCA
CCTATGACGGAGATACGTCTCCGGCCATCAGGCAGAAAGTCAGAAAAGCCGGGCATATTGTGATCACAAATCCCGATATG
CTTCATTCAGCTATTCTTCCCCACCATACAAAATGGGTGAGTCTGTTTGAAAACCTGAAATATATCGTCATTGATGAATT
ACATACGTACCGCGGCGTATTCGGCAGCCATGTGGCGAACGTCATCCGCCGTTTAATGAGAATCTGCGCTTTTTACGGAA
GTACGCCGTCATTTATCTGTACATCCGCCACAATCGCCAATCCGAGGGAATTGGCGGAGCAGCTGACGGGAAAATCAGTG
CGCCTGATTGACGATAACGGCGCCCCGGCCGGAAGAAAGCACTTTGCTTTTTACAATCCTCCGATTGTAAATAAACCGCT
GCATATTCGAAAAAGCGCCACCGTGGAAGTGAACGAACTTGCCAAAACTTTTTTAAAAAATAAGATCCAGACGATTGTTT
TTGCCAGAAGCCGTGTCCGGGTTGAAATTATTTTAAGCCACATTCAGGAGATCGTAAAAAAAGAAATCGGGTCGAAGTCT
GTCAGAGGCTATCGCGGCGGATATCTTCCGAAAGAAAGAAGAGAAATAGAGCGGGGGTTAAGAGACGGAAGCATTCTCGG
CGTTGTCAGCACAAACGCGCTGGAGCTCGGCGTTGATATCGGCCAGCTTCAGGTCTGCGTGATGACGGGGTACCCGGGCA
GTGTCGCGAGCGCATGGCAGCAGGCGGGCCGGGCCGGGCGGCGGCAGGGAGAGGCGCTTATCGTGATGGTGGCGAACTCT
GATCCGATTGACCAATATATTGTCCGCCATCCTGATTATTTCTTTAAACGCTCGCCTGAATCTGCAAGGATTAATCCTGA
TAATCTCATTATATTGGTCGATCACCTGAAATGCGCCGCGTATGAGCTGCCTTTCAGAGCCGATGAAACATTCGGAGAAA
ATGATGCAAGAGACATTCTCGAGTATTTAGAAGAAGAAGGGGTGCTTCACGAAAACCGCGAACGCTATCACTGGGCAAGC
GAATCTTTTCCCGCCTCCAACATCAGTCTCCGTTCGGCGTCACAGGAAAACGTGGTCATCGTTGACCGGTCAGAGACGGC
TGATGTAAAAATCATCGGAGAAATGGACCGCTTCAGCGCGATGACGCTTCTTCATGATGAAGCGATTTATCTTCATGAAG
GGGTGCAGTACCAGGTTGAAAAGCTTGATTGGGACCATAAAAAAGCGTACGTGCGAAAGGTCGATGTCGAATATTATACA
GATGCCAATTTAGCGGTGCAGCTGAAAGTGCTGGACATTGACAGAACGGACAGCAGAAAGAAAACAGCCTTACATTTCGG
CGATGTAACCGTGAACGCACTTCCGACAATATTTAAAAAAATTAAAATGACGACATTTGAAAATATAGGATCAGGGCCGA
TTCATCTTCCAGAAGAAGAACTGCATACCAGTGCTGCCTGGCTTGAATTGAAAGAGACGGATTCGGAGATCGGCGAAAAA
ACGCTTGAACAGCTGCTTTTAGGCATTGCCCACGTCCTGCAGCATATCGTGCCTGTATACGTCATGTGCGACCGAAATGA
CGTGCATGTCGTGCCGCAAATCAAAGCCGCACATACCGGACTTCCGACAATCTTTCTGTATGATCATTATCCGGGCGGAA
TCGGACTTGCCGATGAAGTATATAAGCGATTTGATGAAATCAATGAAGGGGCTGAGCGCCTGATCAGACAATGTCCATGT
CAAGACGGATGTCCTTCCTGCATCGGCTCCGAAATAGAAGGAATAGATGCAAAGAAAGCGATACTCCGGCTCTTGAATTA
CGTGTAA

Upstream 100 bases:

>100_bases
AGGCAGGGGCTGATTCCCTGCTTTTTTTCTTGTGCAGGATTTTCATCTAGCCAGGCAAACAAATATTCGGTAAACTGTAC
CTCATAAAGAGGTGTGAACG

Downstream 100 bases:

>100_bases
AAGAAAAGGGGGACGAAAGATGTCCTTGAAAAATAAATTAAAGCGGATGAAAAACCACCTGAATGTGCCGGAAGCTGAAA
AAAAGCCGGCAGCTTCACAA

Product: YprA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 748; Mature: 748

Protein sequence:

>748_residues
MKKKSLSELIQELKNHENIVHWHEEEPREAKTMPMPEQVDPNIRAALEKRGIERLFTHQYSAFQTVQNGESIVAVTPTAS
GKTLCYNLPVLQSIAEDASSRALYLFPTKALAQDQKSELNEIIDETGMDIKSFTYDGDTSPAIRQKVRKAGHIVITNPDM
LHSAILPHHTKWVSLFENLKYIVIDELHTYRGVFGSHVANVIRRLMRICAFYGSTPSFICTSATIANPRELAEQLTGKSV
RLIDDNGAPAGRKHFAFYNPPIVNKPLHIRKSATVEVNELAKTFLKNKIQTIVFARSRVRVEIILSHIQEIVKKEIGSKS
VRGYRGGYLPKERREIERGLRDGSILGVVSTNALELGVDIGQLQVCVMTGYPGSVASAWQQAGRAGRRQGEALIVMVANS
DPIDQYIVRHPDYFFKRSPESARINPDNLIILVDHLKCAAYELPFRADETFGENDARDILEYLEEEGVLHENRERYHWAS
ESFPASNISLRSASQENVVIVDRSETADVKIIGEMDRFSAMTLLHDEAIYLHEGVQYQVEKLDWDHKKAYVRKVDVEYYT
DANLAVQLKVLDIDRTDSRKKTALHFGDVTVNALPTIFKKIKMTTFENIGSGPIHLPEEELHTSAAWLELKETDSEIGEK
TLEQLLLGIAHVLQHIVPVYVMCDRNDVHVVPQIKAAHTGLPTIFLYDHYPGGIGLADEVYKRFDEINEGAERLIRQCPC
QDGCPSCIGSEIEGIDAKKAILRLLNYV

Sequences:

>Translated_748_residues
MKKKSLSELIQELKNHENIVHWHEEEPREAKTMPMPEQVDPNIRAALEKRGIERLFTHQYSAFQTVQNGESIVAVTPTAS
GKTLCYNLPVLQSIAEDASSRALYLFPTKALAQDQKSELNEIIDETGMDIKSFTYDGDTSPAIRQKVRKAGHIVITNPDM
LHSAILPHHTKWVSLFENLKYIVIDELHTYRGVFGSHVANVIRRLMRICAFYGSTPSFICTSATIANPRELAEQLTGKSV
RLIDDNGAPAGRKHFAFYNPPIVNKPLHIRKSATVEVNELAKTFLKNKIQTIVFARSRVRVEIILSHIQEIVKKEIGSKS
VRGYRGGYLPKERREIERGLRDGSILGVVSTNALELGVDIGQLQVCVMTGYPGSVASAWQQAGRAGRRQGEALIVMVANS
DPIDQYIVRHPDYFFKRSPESARINPDNLIILVDHLKCAAYELPFRADETFGENDARDILEYLEEEGVLHENRERYHWAS
ESFPASNISLRSASQENVVIVDRSETADVKIIGEMDRFSAMTLLHDEAIYLHEGVQYQVEKLDWDHKKAYVRKVDVEYYT
DANLAVQLKVLDIDRTDSRKKTALHFGDVTVNALPTIFKKIKMTTFENIGSGPIHLPEEELHTSAAWLELKETDSEIGEK
TLEQLLLGIAHVLQHIVPVYVMCDRNDVHVVPQIKAAHTGLPTIFLYDHYPGGIGLADEVYKRFDEINEGAERLIRQCPC
QDGCPSCIGSEIEGIDAKKAILRLLNYV
>Mature_748_residues
MKKKSLSELIQELKNHENIVHWHEEEPREAKTMPMPEQVDPNIRAALEKRGIERLFTHQYSAFQTVQNGESIVAVTPTAS
GKTLCYNLPVLQSIAEDASSRALYLFPTKALAQDQKSELNEIIDETGMDIKSFTYDGDTSPAIRQKVRKAGHIVITNPDM
LHSAILPHHTKWVSLFENLKYIVIDELHTYRGVFGSHVANVIRRLMRICAFYGSTPSFICTSATIANPRELAEQLTGKSV
RLIDDNGAPAGRKHFAFYNPPIVNKPLHIRKSATVEVNELAKTFLKNKIQTIVFARSRVRVEIILSHIQEIVKKEIGSKS
VRGYRGGYLPKERREIERGLRDGSILGVVSTNALELGVDIGQLQVCVMTGYPGSVASAWQQAGRAGRRQGEALIVMVANS
DPIDQYIVRHPDYFFKRSPESARINPDNLIILVDHLKCAAYELPFRADETFGENDARDILEYLEEEGVLHENRERYHWAS
ESFPASNISLRSASQENVVIVDRSETADVKIIGEMDRFSAMTLLHDEAIYLHEGVQYQVEKLDWDHKKAYVRKVDVEYYT
DANLAVQLKVLDIDRTDSRKKTALHFGDVTVNALPTIFKKIKMTTFENIGSGPIHLPEEELHTSAAWLELKETDSEIGEK
TLEQLLLGIAHVLQHIVPVYVMCDRNDVHVVPQIKAAHTGLPTIFLYDHYPGGIGLADEVYKRFDEINEGAERLIRQCPC
QDGCPSCIGSEIEGIDAKKAILRLLNYV

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320497, Length=768, Percent_Identity=32.8125, Blast_Score=403, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI9755332, Length=383, Percent_Identity=23.7597911227154, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 84362; Mature: 84362

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKSLSELIQELKNHENIVHWHEEEPREAKTMPMPEQVDPNIRAALEKRGIERLFTHQY
CCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SAFQTVQNGESIVAVTPTASGKTLCYNLPVLQSIAEDASSRALYLFPTKALAQDQKSELN
HHHHHHCCCCEEEEEECCCCCCEEEEECHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHH
EIIDETGMDIKSFTYDGDTSPAIRQKVRKAGHIVITNPDMLHSAILPHHTKWVSLFENLK
HHHHHCCCCCEEEECCCCCCHHHHHHHHHCCEEEEECCHHHHHHHCCCHHHHHHHHHCCC
YIVIDELHTYRGVFGSHVANVIRRLMRICAFYGSTPSFICTSATIANPRELAEQLTGKSV
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCEE
RLIDDNGAPAGRKHFAFYNPPIVNKPLHIRKSATVEVNELAKTFLKNKIQTIVFARSRVR
EEEECCCCCCCCCCEEEECCCCCCCCCEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
VEIILSHIQEIVKKEIGSKSVRGYRGGYLPKERREIERGLRDGSILGVVSTNALELGVDI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCEEECCCC
GQLQVCVMTGYPGSVASAWQQAGRAGRRQGEALIVMVANSDPIDQYIVRHPDYFFKRSPE
CCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHCCCCHHHHCCCC
SARINPDNLIILVDHLKCAAYELPFRADETFGENDARDILEYLEEEGVLHENRERYHWAS
CCCCCCCCEEEEEECCCCHHEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCC
ESFPASNISLRSASQENVVIVDRSETADVKIIGEMDRFSAMTLLHDEAIYLHEGVQYQVE
CCCCCCCCEEECCCCCCEEEEECCCCCCEEEEECHHHHHHHHHHCCCEEEEECCCCHHHH
KLDWDHKKAYVRKVDVEYYTDANLAVQLKVLDIDRTDSRKKTALHFGDVTVNALPTIFKK
HCCCCHHHHHHEEECEEEEECCCEEEEEEEEECCCCCCCCHHEEEECCEEHHHHHHHHHH
IKMTTFENIGSGPIHLPEEELHTSAAWLELKETDSEIGEKTLEQLLLGIAHVLQHIVPVY
HHHHHHHCCCCCCCCCCHHHHHCHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
VMCDRNDVHVVPQIKAAHTGLPTIFLYDHYPGGIGLADEVYKRFDEINEGAERLIRQCPC
EEECCCCEEEECCHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
QDGCPSCIGSEIEGIDAKKAILRLLNYV
CCCCCHHHCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKKKSLSELIQELKNHENIVHWHEEEPREAKTMPMPEQVDPNIRAALEKRGIERLFTHQY
CCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SAFQTVQNGESIVAVTPTASGKTLCYNLPVLQSIAEDASSRALYLFPTKALAQDQKSELN
HHHHHHCCCCEEEEEECCCCCCEEEEECHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHH
EIIDETGMDIKSFTYDGDTSPAIRQKVRKAGHIVITNPDMLHSAILPHHTKWVSLFENLK
HHHHHCCCCCEEEECCCCCCHHHHHHHHHCCEEEEECCHHHHHHHCCCHHHHHHHHHCCC
YIVIDELHTYRGVFGSHVANVIRRLMRICAFYGSTPSFICTSATIANPRELAEQLTGKSV
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCEE
RLIDDNGAPAGRKHFAFYNPPIVNKPLHIRKSATVEVNELAKTFLKNKIQTIVFARSRVR
EEEECCCCCCCCCCEEEECCCCCCCCCEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
VEIILSHIQEIVKKEIGSKSVRGYRGGYLPKERREIERGLRDGSILGVVSTNALELGVDI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCEEECCCC
GQLQVCVMTGYPGSVASAWQQAGRAGRRQGEALIVMVANSDPIDQYIVRHPDYFFKRSPE
CCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHCCCCHHHHCCCC
SARINPDNLIILVDHLKCAAYELPFRADETFGENDARDILEYLEEEGVLHENRERYHWAS
CCCCCCCCEEEEEECCCCHHEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCC
ESFPASNISLRSASQENVVIVDRSETADVKIIGEMDRFSAMTLLHDEAIYLHEGVQYQVE
CCCCCCCCEEECCCCCCEEEEECCCCCCEEEEECHHHHHHHHHHCCCEEEEECCCCHHHH
KLDWDHKKAYVRKVDVEYYTDANLAVQLKVLDIDRTDSRKKTALHFGDVTVNALPTIFKK
HCCCCHHHHHHEEECEEEEECCCEEEEEEEEECCCCCCCCHHEEEECCEEHHHHHHHHHH
IKMTTFENIGSGPIHLPEEELHTSAAWLELKETDSEIGEKTLEQLLLGIAHVLQHIVPVY
HHHHHHHCCCCCCCCCCHHHHHCHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
VMCDRNDVHVVPQIKAAHTGLPTIFLYDHYPGGIGLADEVYKRFDEINEGAERLIRQCPC
EEECCCCEEEECCHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
QDGCPSCIGSEIEGIDAKKAILRLLNYV
CCCCCHHHCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]