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The map label for this gene is yocI [H]

Identifier: 154686329

GI number: 154686329

Start: 2017691

End: 2019469

Strand: Reverse

Name: yocI [H]

Synonym: RBAM_018970

Alternate gene names: 154686329

Gene position: 2019469-2017691 (Counterclockwise)

Preceding gene: 154686330

Following gene: 154686328

Centisome position: 51.54

GC content: 46.26

Gene sequence:

>1779_bases
ATGCTGGAGAAAGCCCAATCCCTTCTGGCGCATTATTTTGGCTACGACAGTCTTCGCGCGGGCCAAAAGCAGGCGATACA
ATCAGTTGCAGAGAAAAGAAAAAACACGGTCTGCATTATGCCGACAGGGGGCGGAAAATCAATCTGCTATCAGATTCCCG
CACTGCTGTTTGAAGGAACCACAATCGTTATTTCCCCTCTTATTTCCTTAATGAAAGATCAAGTCGACGCGCTTGAAGAA
GCGGGTATCGCGGCAGCTTATATTAACAGCACCCAGACAAGCCGTGACATTCATGAGCGCCTGACCGGTTTGAAACAAGG
GGCTTACCGGCTCTTTTACATCACACCGGAGCGTTTGACTTCTTCTGAATTCATTCACATCCTGCAGAATATTACGGTTC
CTCTTGTCGCCATTGACGAAGCTCACTGTATATCGCAATGGGGACATGATTTCAGGCCGAGTTACCGGAATATCGAAATC
CTTTTTAATGAATTAAAAGAACCGCCCGTCATCATCGCATTAACGGCGACGGCTACGCCTGAGGTTCATGATGACATCTG
CAAACAGCTTCATATTAAGAAAGAACAAACTGTATATACCGGTTTTGCCAGAGAGAATTTAACGTTTAAAGTAGTAAAGG
GCGAAAACAAAGACCGGTTTATCGAGCGGTACCTGGAAAAAAATAAACACGAAGCCGGCATTATATATACAGCGACAAGA
AAAGAAACCGACCGTTTATATGATAAATTAAAACGCAGCGGCATCAATGCCGGCCGTTATCACGGCGGATTGGCGGATGA
TGACAGAAAAGACCAGCAGGAGCGGTTTCTTAACGATCAGATACAAGTGATGGTAGCTACGTCCGCTTTCGGAATGGGAA
TCGATAAGAGCAACATCAGATTCGTTTTGCACGCGCAGATTCCGAAAGATATGGAGAGCTATTACCAAGAAGCCGGACGG
GCCGGGCGCGATGGTCTTAACAGCGAGTGTGTGCTCTTGTTTTCGCCGCAGGATATTATGGTGCAGCGTTTTTTAATAGA
CCAATCGGCCGCCGGAGAAGAAAAACAAAAGCAGGATCTCAAAAAACTGAGACAGATGGTGGATTACTGTCATACGGAAG
ATTGCCTGCAGCGGTTTATTCTGAAGTATTTCGGCGAGAATGAGGCGGAAGCTTGCGGAGCATGCGGCAATTGCACTGAT
ACAAGGACCGCCCATGACGTCACAAAAGAAGCGCAGATGGTATTGTCATGCATCATCAGAATGAATGAGCGCTTCGGAAA
AACGATGGTGGCGCAGGTGCTTAGCGGGTCAAAAAATAAAAAAGTGCTGGAAAACGGCTTCAGCAGCCTGTCCACTTACG
GCATTATGAAGCATCAATCCGCAGCGGAAATCAGTGATTTTATCGAATTCCTTATTTCAGATGAATATATCAGAATGGCG
GACGGCACATTTCCGACGCTTATGGTCACCCAAAAAGGCAGGGATGTTTTGCTTGGAAAAAGCGCAGTCGCGAGAAAAGA
AGCCTTACAGGCCGCCGCCGTTACCGAAAATGATGAATTATTTGAGCTTCTCCGGCGTCTCCGCAAAGAGATTGCAGCTG
AACAGGGCGTGCCTCCATTTGTCGTGTTCTCAGATCAGACGTTAAAAGAAATGTCGGCGAAACTTCCGAAAACAGATCAG
GATCTTCTTTCCGTAAAAGGGGTCGGGGAACAAAAAAGATTGAAATACGGAGCGGTTTTTTTAGAAGAAATCCGAAATTA
TGTAAGAGAAACAGAGTGA

Upstream 100 bases:

>100_bases
CTTGCGGAGATGGCTTTTTATTTTGAATTGCCATTGAGCAGCGTACTTTATCAGTATGATAAAATGAAAGAATCAAAGAC
AAAGTGAGGTTTTACAACAT

Downstream 100 bases:

>100_bases
AAAAAAGTTTTTTTAGAAATTTGCACATTGTGTTTTTCATTCGCGCCGGAAAAATCAGAAGCTTGAAAACCCTTGCTGTA
TCAAGGTTTCAGCAAGACTT

Product: YocI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MLEKAQSLLAHYFGYDSLRAGQKQAIQSVAEKRKNTVCIMPTGGGKSICYQIPALLFEGTTIVISPLISLMKDQVDALEE
AGIAAAYINSTQTSRDIHERLTGLKQGAYRLFYITPERLTSSEFIHILQNITVPLVAIDEAHCISQWGHDFRPSYRNIEI
LFNELKEPPVIIALTATATPEVHDDICKQLHIKKEQTVYTGFARENLTFKVVKGENKDRFIERYLEKNKHEAGIIYTATR
KETDRLYDKLKRSGINAGRYHGGLADDDRKDQQERFLNDQIQVMVATSAFGMGIDKSNIRFVLHAQIPKDMESYYQEAGR
AGRDGLNSECVLLFSPQDIMVQRFLIDQSAAGEEKQKQDLKKLRQMVDYCHTEDCLQRFILKYFGENEAEACGACGNCTD
TRTAHDVTKEAQMVLSCIIRMNERFGKTMVAQVLSGSKNKKVLENGFSSLSTYGIMKHQSAAEISDFIEFLISDEYIRMA
DGTFPTLMVTQKGRDVLLGKSAVARKEALQAAAVTENDELFELLRRLRKEIAAEQGVPPFVVFSDQTLKEMSAKLPKTDQ
DLLSVKGVGEQKRLKYGAVFLEEIRNYVRETE

Sequences:

>Translated_592_residues
MLEKAQSLLAHYFGYDSLRAGQKQAIQSVAEKRKNTVCIMPTGGGKSICYQIPALLFEGTTIVISPLISLMKDQVDALEE
AGIAAAYINSTQTSRDIHERLTGLKQGAYRLFYITPERLTSSEFIHILQNITVPLVAIDEAHCISQWGHDFRPSYRNIEI
LFNELKEPPVIIALTATATPEVHDDICKQLHIKKEQTVYTGFARENLTFKVVKGENKDRFIERYLEKNKHEAGIIYTATR
KETDRLYDKLKRSGINAGRYHGGLADDDRKDQQERFLNDQIQVMVATSAFGMGIDKSNIRFVLHAQIPKDMESYYQEAGR
AGRDGLNSECVLLFSPQDIMVQRFLIDQSAAGEEKQKQDLKKLRQMVDYCHTEDCLQRFILKYFGENEAEACGACGNCTD
TRTAHDVTKEAQMVLSCIIRMNERFGKTMVAQVLSGSKNKKVLENGFSSLSTYGIMKHQSAAEISDFIEFLISDEYIRMA
DGTFPTLMVTQKGRDVLLGKSAVARKEALQAAAVTENDELFELLRRLRKEIAAEQGVPPFVVFSDQTLKEMSAKLPKTDQ
DLLSVKGVGEQKRLKYGAVFLEEIRNYVRETE
>Mature_592_residues
MLEKAQSLLAHYFGYDSLRAGQKQAIQSVAEKRKNTVCIMPTGGGKSICYQIPALLFEGTTIVISPLISLMKDQVDALEE
AGIAAAYINSTQTSRDIHERLTGLKQGAYRLFYITPERLTSSEFIHILQNITVPLVAIDEAHCISQWGHDFRPSYRNIEI
LFNELKEPPVIIALTATATPEVHDDICKQLHIKKEQTVYTGFARENLTFKVVKGENKDRFIERYLEKNKHEAGIIYTATR
KETDRLYDKLKRSGINAGRYHGGLADDDRKDQQERFLNDQIQVMVATSAFGMGIDKSNIRFVLHAQIPKDMESYYQEAGR
AGRDGLNSECVLLFSPQDIMVQRFLIDQSAAGEEKQKQDLKKLRQMVDYCHTEDCLQRFILKYFGENEAEACGACGNCTD
TRTAHDVTKEAQMVLSCIIRMNERFGKTMVAQVLSGSKNKKVLENGFSSLSTYGIMKHQSAAEISDFIEFLISDEYIRMA
DGTFPTLMVTQKGRDVLLGKSAVARKEALQAAAVTENDELFELLRRLRKEIAAEQGVPPFVVFSDQTLKEMSAKLPKTDQ
DLLSVKGVGEQKRLKYGAVFLEEIRNYVRETE

Specific function: Probable DNA helicase. Required for DNA repair and intramolecular recombination; probably has overlapping function with recS (AC P50729). It probably acts to help generate ss-DNA from ds-DNA breaks [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Localized throughout the nucleoid in the presence or absence of DNA double- strand breaks [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=633, Percent_Identity=34.4391785150079, Blast_Score=326, Evalue=5e-89,
Organism=Homo sapiens, GI110735439, Length=550, Percent_Identity=35.6363636363636, Blast_Score=312, Evalue=7e-85,
Organism=Homo sapiens, GI169218196, Length=550, Percent_Identity=35.6363636363636, Blast_Score=311, Evalue=9e-85,
Organism=Homo sapiens, GI148612816, Length=428, Percent_Identity=38.3177570093458, Blast_Score=270, Evalue=3e-72,
Organism=Homo sapiens, GI14591902, Length=411, Percent_Identity=37.956204379562, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI14591904, Length=411, Percent_Identity=37.956204379562, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI51242943, Length=373, Percent_Identity=39.6782841823056, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI51242947, Length=373, Percent_Identity=39.6782841823056, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI284005309, Length=419, Percent_Identity=31.7422434367542, Blast_Score=198, Evalue=2e-50,
Organism=Homo sapiens, GI301171475, Length=368, Percent_Identity=23.9130434782609, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI87196351, Length=368, Percent_Identity=23.9130434782609, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI301171467, Length=368, Percent_Identity=23.9130434782609, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI48994977, Length=596, Percent_Identity=41.2751677852349, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI87082221, Length=336, Percent_Identity=23.2142857142857, Blast_Score=73, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25145561, Length=651, Percent_Identity=30.4147465437788, Blast_Score=303, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI71987997, Length=515, Percent_Identity=33.9805825242718, Blast_Score=274, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI71987993, Length=515, Percent_Identity=33.9805825242718, Blast_Score=273, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI32564293, Length=479, Percent_Identity=35.6993736951983, Blast_Score=270, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17552866, Length=454, Percent_Identity=33.4801762114537, Blast_Score=249, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17507945, Length=329, Percent_Identity=24.0121580547112, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI86570094, Length=351, Percent_Identity=24.2165242165242, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=519, Percent_Identity=35.2601156069364, Blast_Score=298, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24646066, Length=633, Percent_Identity=34.5971563981043, Blast_Score=334, Evalue=9e-92,
Organism=Drosophila melanogaster, GI24664226, Length=429, Percent_Identity=33.5664335664336, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI62472181, Length=429, Percent_Identity=33.5664335664336, Blast_Score=243, Evalue=3e-64,
Organism=Drosophila melanogaster, GI24664230, Length=429, Percent_Identity=33.5664335664336, Blast_Score=243, Evalue=3e-64,
Organism=Drosophila melanogaster, GI21358123, Length=356, Percent_Identity=34.8314606741573, Blast_Score=193, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 66871; Mature: 66871

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKAQSLLAHYFGYDSLRAGQKQAIQSVAEKRKNTVCIMPTGGGKSICYQIPALLFEGT
CCHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCC
TIVISPLISLMKDQVDALEEAGIAAAYINSTQTSRDIHERLTGLKQGAYRLFYITPERLT
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECHHHHC
SSEFIHILQNITVPLVAIDEAHCISQWGHDFRPSYRNIEILFNELKEPPVIIALTATATP
HHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCC
EVHDDICKQLHIKKEQTVYTGFARENLTFKVVKGENKDRFIERYLEKNKHEAGIIYTATR
HHHHHHHHHHCCCCHHHEEEEEECCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEEECC
KETDRLYDKLKRSGINAGRYHGGLADDDRKDQQERFLNDQIQVMVATSAFGMGIDKSNIR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCHHHEEEEEEHHHCCCCCCCCCE
FVLHAQIPKDMESYYQEAGRAGRDGLNSECVLLFSPQDIMVQRFLIDQSAAGEEKQKQDL
EEEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHHH
KKLRQMVDYCHTEDCLQRFILKYFGENEAEACGACGNCTDTRTAHDVTKEAQMVLSCIIR
HHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MNERFGKTMVAQVLSGSKNKKVLENGFSSLSTYGIMKHQSAAEISDFIEFLISDEYIRMA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEC
DGTFPTLMVTQKGRDVLLGKSAVARKEALQAAAVTENDELFELLRRLRKEIAAEQGVPPF
CCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCE
VVFSDQTLKEMSAKLPKTDQDLLSVKGVGEQKRLKYGAVFLEEIRNYVRETE
EEECCHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLEKAQSLLAHYFGYDSLRAGQKQAIQSVAEKRKNTVCIMPTGGGKSICYQIPALLFEGT
CCHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCC
TIVISPLISLMKDQVDALEEAGIAAAYINSTQTSRDIHERLTGLKQGAYRLFYITPERLT
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECHHHHC
SSEFIHILQNITVPLVAIDEAHCISQWGHDFRPSYRNIEILFNELKEPPVIIALTATATP
HHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCC
EVHDDICKQLHIKKEQTVYTGFARENLTFKVVKGENKDRFIERYLEKNKHEAGIIYTATR
HHHHHHHHHHCCCCHHHEEEEEECCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEEECC
KETDRLYDKLKRSGINAGRYHGGLADDDRKDQQERFLNDQIQVMVATSAFGMGIDKSNIR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCHHHEEEEEEHHHCCCCCCCCCE
FVLHAQIPKDMESYYQEAGRAGRDGLNSECVLLFSPQDIMVQRFLIDQSAAGEEKQKQDL
EEEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHHH
KKLRQMVDYCHTEDCLQRFILKYFGENEAEACGACGNCTDTRTAHDVTKEAQMVLSCIIR
HHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MNERFGKTMVAQVLSGSKNKKVLENGFSSLSTYGIMKHQSAAEISDFIEFLISDEYIRMA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEC
DGTFPTLMVTQKGRDVLLGKSAVARKEALQAAAVTENDELFELLRRLRKEIAAEQGVPPF
CCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCE
VVFSDQTLKEMSAKLPKTDQDLLSVKGVGEQKRLKYGAVFLEEIRNYVRETE
EEECCHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9642195 [H]