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The map label for this gene is yoeA [H]

Identifier: 154686282

GI number: 154686282

Start: 1972055

End: 1973443

Strand: Reverse

Name: yoeA [H]

Synonym: RBAM_018490

Alternate gene names: 154686282

Gene position: 1973443-1972055 (Counterclockwise)

Preceding gene: 154686284

Following gene: 154686281

Centisome position: 50.36

GC content: 47.44

Gene sequence:

>1389_bases
ATGGAAGTACAAGATCATTTAGAAACAGCGGAAGGCCGCGGCCAGTCAGTCTGGCGATCGATGTCACTGTTTTTAGTGCC
GCTGCTTTTAAGCAATGTATTGCAATCTGTCGGCCAATTGGTCGGAATGGTATTTGTCGGAAGGTGGCTCGGAGTCGATG
CGCTTGCCGCCGTATCGTCTTTTTTTCCGCTGTTTTTTCTGCTGATCTCCTTTACGATCGGAATCGGTTCGGGAAGTTCC
ATTCTGATCGGGCAGGCTTACGGCGCGAAAAACGAAGAGAGGATGAAGGCGATTGTCGGCACTACACTGACTTTTACCTT
TATGCTCGGTGTTGTTCTGGCAGTTGTCGGCAGTGTGTTTACGCTTGATATTCTGCGGCTGATGGGAACGCCGGAAAACG
TAATAGATGTCAGTGTCCGATATGCGCGCATTTTGTTTTGCGCAATGCCGCTGATGTTTTTATATTTTGCGTATACGACA
TTTTTACGCGGAACGGGAGATTCAAAGACTCCGTTTTATACGTTAATCGTCAGTACAGTCATAAACATCGGGCTTTTGCC
CTTATTGATTCTCGGGCTTTTCGGACTTCCGAAGTTCGGCATTTACGGTTCGGCGTATGCAACCGTGATTTCAAACATCG
TGACATTTATCGTACTCATGGTTTATTTGCGGAAAAGGAAACATCCATTGGCATTTGATCGGACTGCGCTCCGTTCTCTT
AAAATGGACAAAAAGCTGCTCGCGCTTTTACTCCGTCTCGGTATTCCGTCGAGCATCAATATGATTCTCGTGTCACTTTC
TGAAATTGCGGTCATTTCATTTGTCAATCATTACGGATCAAACGCGACGGCTGCTTACGGGGTCGTCAACCAAGTGGCGA
GTTATGTGCAGATGCCGGCGGTAAGCCTCGGTATCGCCGTTTCCATTTTTGCCGCCCAATCCATTGGCGCCAATCAATTC
GGCCGGCTGAAACAGGTCATCAAAGTCGGCATCGGCCTGAATTATTTGATCGGCGGGGTTTTGATTGTGCTGATTTATAC
CTTCTCCCGGCAGATACTTGCTTTGTTTTTAACAGATCAGGACACGCTCCACATTGCCCGCAATCTGATTATGATTACCC
TTTGGAGCTATTTGATTTTCGGTCATGCTCAGATCGTTTCAGCAACGATGCGGGCGAGCGGTACGGTGTTATGGCCGACG
ATTATCAGCATTTTTGCGATTTGGGGAATTGAAGTGCCTGTGGCCTTTATTCTTTCTCATTATACGAATCTCGGCATTCT
CGGCATTTGGGTCGGTTATCCGGCGGCTTTTGTCGTCAGCCTGCTGCTGCAATACGGATATTACCGGTTTGTATGGAAGA
AAAAACAGATCACCCGGCTGATTCAATAA

Upstream 100 bases:

>100_bases
AGACGTGAGAAAAAGATAAAGAGTTTCATTGAACAAAAGGTTTTTACAAGCTGTCTGCTGAATAATAAAATGGAAGAAAA
TCAAAAAAGGAGTCCTACAT

Downstream 100 bases:

>100_bases
GGTTTTACCGCACATCGCTCAGTTCATACGGGCGATGTTTTTTTAGAGAAGGAAAATGAGTTTAGAAAATGGAATTCCTA
TACATGCTAGAAAACAAGGA

Product: YoeA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MEVQDHLETAEGRGQSVWRSMSLFLVPLLLSNVLQSVGQLVGMVFVGRWLGVDALAAVSSFFPLFFLLISFTIGIGSGSS
ILIGQAYGAKNEERMKAIVGTTLTFTFMLGVVLAVVGSVFTLDILRLMGTPENVIDVSVRYARILFCAMPLMFLYFAYTT
FLRGTGDSKTPFYTLIVSTVINIGLLPLLILGLFGLPKFGIYGSAYATVISNIVTFIVLMVYLRKRKHPLAFDRTALRSL
KMDKKLLALLLRLGIPSSINMILVSLSEIAVISFVNHYGSNATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANQF
GRLKQVIKVGIGLNYLIGGVLIVLIYTFSRQILALFLTDQDTLHIARNLIMITLWSYLIFGHAQIVSATMRASGTVLWPT
IISIFAIWGIEVPVAFILSHYTNLGILGIWVGYPAAFVVSLLLQYGYYRFVWKKKQITRLIQ

Sequences:

>Translated_462_residues
MEVQDHLETAEGRGQSVWRSMSLFLVPLLLSNVLQSVGQLVGMVFVGRWLGVDALAAVSSFFPLFFLLISFTIGIGSGSS
ILIGQAYGAKNEERMKAIVGTTLTFTFMLGVVLAVVGSVFTLDILRLMGTPENVIDVSVRYARILFCAMPLMFLYFAYTT
FLRGTGDSKTPFYTLIVSTVINIGLLPLLILGLFGLPKFGIYGSAYATVISNIVTFIVLMVYLRKRKHPLAFDRTALRSL
KMDKKLLALLLRLGIPSSINMILVSLSEIAVISFVNHYGSNATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANQF
GRLKQVIKVGIGLNYLIGGVLIVLIYTFSRQILALFLTDQDTLHIARNLIMITLWSYLIFGHAQIVSATMRASGTVLWPT
IISIFAIWGIEVPVAFILSHYTNLGILGIWVGYPAAFVVSLLLQYGYYRFVWKKKQITRLIQ
>Mature_462_residues
MEVQDHLETAEGRGQSVWRSMSLFLVPLLLSNVLQSVGQLVGMVFVGRWLGVDALAAVSSFFPLFFLLISFTIGIGSGSS
ILIGQAYGAKNEERMKAIVGTTLTFTFMLGVVLAVVGSVFTLDILRLMGTPENVIDVSVRYARILFCAMPLMFLYFAYTT
FLRGTGDSKTPFYTLIVSTVINIGLLPLLILGLFGLPKFGIYGSAYATVISNIVTFIVLMVYLRKRKHPLAFDRTALRSL
KMDKKLLALLLRLGIPSSINMILVSLSEIAVISFVNHYGSNATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANQF
GRLKQVIKVGIGLNYLIGGVLIVLIYTFSRQILALFLTDQDTLHIARNLIMITLWSYLIFGHAQIVSATMRASGTVLWPT
IISIFAIWGIEVPVAFILSHYTNLGILGIWVGYPAAFVVSLLLQYGYYRFVWKKKQITRLIQ

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Homo sapiens, GI22907060, Length=389, Percent_Identity=24.1645244215938, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI226510954, Length=445, Percent_Identity=21.5730337078652, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 50805; Mature: 50805

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCHHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEVQDHLETAEGRGQSVWRSMSLFLVPLLLSNVLQSVGQLVGMVFVGRWLGVDALAAVSS
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFPLFFLLISFTIGIGSGSSILIGQAYGAKNEERMKAIVGTTLTFTFMLGVVLAVVGSVF
HHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLDILRLMGTPENVIDVSVRYARILFCAMPLMFLYFAYTTFLRGTGDSKTPFYTLIVSTV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
INIGLLPLLILGLFGLPKFGIYGSAYATVISNIVTFIVLMVYLRKRKHPLAFDRTALRSL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KMDKKLLALLLRLGIPSSINMILVSLSEIAVISFVNHYGSNATAAYGVVNQVASYVQMPA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCH
VSLGIAVSIFAAQSIGANQFGRLKQVIKVGIGLNYLIGGVLIVLIYTFSRQILALFLTDQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DTLHIARNLIMITLWSYLIFGHAQIVSATMRASGTVLWPTIISIFAIWGIEVPVAFILSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YTNLGILGIWVGYPAAFVVSLLLQYGYYRFVWKKKQITRLIQ
HCCCCHHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]