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The map label for this gene is dacC [H]

Identifier: 154686280

GI number: 154686280

Start: 1969478

End: 1970953

Strand: Reverse

Name: dacC [H]

Synonym: RBAM_018470

Alternate gene names: 154686280

Gene position: 1970953-1969478 (Counterclockwise)

Preceding gene: 154686281

Following gene: 154686279

Centisome position: 50.3

GC content: 49.12

Gene sequence:

>1476_bases
TTGAAAACATATGTGAAACGCTTGAGCGCGGTGATTCTGCTTTTGATCATTGCCGCAGTTCCTTATATTGATGATGCGGC
TAAGGCGGCTGAACAAAAAAATACTTTGCAAAAAGAGCTGGAACACATTCTGGATGAAGAACCAACTTTAAAGGGAGCTT
CAGCGGGCGTCAGTGTCCGGTCAGCAAAAACAGGGGAGGTGCTGTTCGGCAGCCGGGAAGATATGCGGCTGCGGCCTGCA
TCACTGATGAAGCTGCTGACGGCATCTGCAGCGCTTTCCGTTCTCGGAGAAGATTACACCTTTAAGACAGAAGTACGGGC
AGACGGCGCCGTAAAAGGAAAACAGCTGCGCGGAAACCTTTATCTCAGGGGAAAAGGCGATCCGACCCTATTGGTTTCTG
ATTTTGAGAAGATGGCTAAACAGGTCAAAGCCAGGGGCATCCATGTCATTAAAGGAGATCTGGTCGGGGATGATTCGTGG
TATGACGATACCAGGTATTCAGTTGATCTTCCGTGGAGCGATGAAGGCCAATATTATGGCGCGCAAGTATCAGCTCTTAC
CGCTTCACCAAATGAGGATTATGATACCGGAACGGTGATTGCGGAAATCAGCCCGGCGAAACAGCCCGGTAAAAAGCCGC
GCATTTCGATTTCTCCCCATACGGACGTCGTTCGTGTGAAAAATGAAGTGAAAACCGTCGCTTCTGATGAAAAGAAAGAT
TTGACGGTTGAACGGGAGCACGGTGGCAATGTGATTACGATAAAGGGAACCATACCTGCCGGCTCGGCACAGGCAAGAGA
ATGGGCGGCAGTGTGGGATCCGTCGTCCTATGCTTTAGATTTATGGAAACAAGCGCTTACTAAACAGGGTATAACTGTAA
AAGGGAAAATCAGAACAGGGCGAATGCCGCACCGCACCCAGCTTGTCACATCACGGACATCCATGCCTCTTTCAGAATTA
TTGATCCCGTTTATGAAACTGAGCAACAACGGGCACGCCGAAATTCTGATCAAGGAAATGGGAAAAGTGAAAAAAGGGGA
GGGCAGCTGGGAAAAGGGCTTGGACGTGATGAAATCAGAGCTCAAATCGTTCGGGCTGAATCCGGATGAATTGATTGCAA
GAGACGGATCAGGCGTTTCTCATATTAACGGCGTATCCGCCGGCCAAATCGGAGAGCTTTTGTATGCGGTTCAGAAAGAA
AAGTGGTACCCGGCTTTCCTTCGTTCGCTTCCTGTCGCCGGTGCAAGTGACAGAATGACGGGAGGAACCCTTCGGAATCG
GCTGAAGGGCACCCCGGCGGAGGGAAAGATTAAAGCGAAAACCGGATCACTAACATCAGTCAGTTCGATTGCCGGCTATG
CAGACACAAAAACAGGAGATACGCTTATTTTTTCCGTGCTTCAAAATGGGCTGCTTGACGAAGATGACGGAAAAGACATT
GAAGACAAAATTGCAGTCGTGCTGGCAAATCAATAA

Upstream 100 bases:

>100_bases
ACTGACAGGGCTTCAGATTCTGAAACCGGGCGAAGAAGCGGCTGCGTCATCCAGGATCACCATTTTGCATGACGAAGAAT
AGGAAAGAGGCGGGATAACA

Downstream 100 bases:

>100_bases
GAAGGGCCGAATCCTTAGAGGATTCGGCTTTTTATGATGTCTGTAAAACATTATATTGCGATTATGAATCAATCTTTTCA
AAAAGTAATATCGGTAATAT

Product: hypothetical protein

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 4a; PBP-4a [H]

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MKTYVKRLSAVILLLIIAAVPYIDDAAKAAEQKNTLQKELEHILDEEPTLKGASAGVSVRSAKTGEVLFGSREDMRLRPA
SLMKLLTASAALSVLGEDYTFKTEVRADGAVKGKQLRGNLYLRGKGDPTLLVSDFEKMAKQVKARGIHVIKGDLVGDDSW
YDDTRYSVDLPWSDEGQYYGAQVSALTASPNEDYDTGTVIAEISPAKQPGKKPRISISPHTDVVRVKNEVKTVASDEKKD
LTVEREHGGNVITIKGTIPAGSAQAREWAAVWDPSSYALDLWKQALTKQGITVKGKIRTGRMPHRTQLVTSRTSMPLSEL
LIPFMKLSNNGHAEILIKEMGKVKKGEGSWEKGLDVMKSELKSFGLNPDELIARDGSGVSHINGVSAGQIGELLYAVQKE
KWYPAFLRSLPVAGASDRMTGGTLRNRLKGTPAEGKIKAKTGSLTSVSSIAGYADTKTGDTLIFSVLQNGLLDEDDGKDI
EDKIAVVLANQ

Sequences:

>Translated_491_residues
MKTYVKRLSAVILLLIIAAVPYIDDAAKAAEQKNTLQKELEHILDEEPTLKGASAGVSVRSAKTGEVLFGSREDMRLRPA
SLMKLLTASAALSVLGEDYTFKTEVRADGAVKGKQLRGNLYLRGKGDPTLLVSDFEKMAKQVKARGIHVIKGDLVGDDSW
YDDTRYSVDLPWSDEGQYYGAQVSALTASPNEDYDTGTVIAEISPAKQPGKKPRISISPHTDVVRVKNEVKTVASDEKKD
LTVEREHGGNVITIKGTIPAGSAQAREWAAVWDPSSYALDLWKQALTKQGITVKGKIRTGRMPHRTQLVTSRTSMPLSEL
LIPFMKLSNNGHAEILIKEMGKVKKGEGSWEKGLDVMKSELKSFGLNPDELIARDGSGVSHINGVSAGQIGELLYAVQKE
KWYPAFLRSLPVAGASDRMTGGTLRNRLKGTPAEGKIKAKTGSLTSVSSIAGYADTKTGDTLIFSVLQNGLLDEDDGKDI
EDKIAVVLANQ
>Mature_491_residues
MKTYVKRLSAVILLLIIAAVPYIDDAAKAAEQKNTLQKELEHILDEEPTLKGASAGVSVRSAKTGEVLFGSREDMRLRPA
SLMKLLTASAALSVLGEDYTFKTEVRADGAVKGKQLRGNLYLRGKGDPTLLVSDFEKMAKQVKARGIHVIKGDLVGDDSW
YDDTRYSVDLPWSDEGQYYGAQVSALTASPNEDYDTGTVIAEISPAKQPGKKPRISISPHTDVVRVKNEVKTVASDEKKD
LTVEREHGGNVITIKGTIPAGSAQAREWAAVWDPSSYALDLWKQALTKQGITVKGKIRTGRMPHRTQLVTSRTSMPLSEL
LIPFMKLSNNGHAEILIKEMGKVKKGEGSWEKGLDVMKSELKSFGLNPDELIARDGSGVSHINGVSAGQIGELLYAVQKE
KWYPAFLRSLPVAGASDRMTGGTLRNRLKGTPAEGKIKAKTGSLTSVSSIAGYADTKTGDTLIFSVLQNGLLDEDDGKDI
EDKIAVVLANQ

Specific function: Catalyzes DD-carboxypeptidase and transpeptidation reactions [H]

COG id: COG2027

COG function: function code M; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)

Gene ontology:

Cell location: Secreted (Probable). Note=May be anchored in the membrane via a C-terminal amphiphatic alpha helix [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S13 family [H]

Homologues:

Organism=Escherichia coli, GI1789573, Length=394, Percent_Identity=29.4416243654822, Blast_Score=139, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR000667 [H]

Pfam domain/function: PF02113 Peptidase_S13 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 53220; Mature: 53220

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYVKRLSAVILLLIIAAVPYIDDAAKAAEQKNTLQKELEHILDEEPTLKGASAGVSVR
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
SAKTGEVLFGSREDMRLRPASLMKLLTASAALSVLGEDYTFKTEVRADGAVKGKQLRGNL
CCCCCCEEECCCCCCEECHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECEE
YLRGKGDPTLLVSDFEKMAKQVKARGIHVIKGDLVGDDSWYDDTRYSVDLPWSDEGQYYG
EEEECCCCEEEHHHHHHHHHHHHHCCEEEEECCEECCCCCCCCCCEEEECCCCCCCCEEC
AQVSALTASPNEDYDTGTVIAEISPAKQPGKKPRISISPHTDVVRVKNEVKTVASDEKKD
EEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCC
LTVEREHGGNVITIKGTIPAGSAQAREWAAVWDPSSYALDLWKQALTKQGITVKGKIRTG
CEEEECCCCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECC
RMPHRTQLVTSRTSMPLSELLIPFMKLSNNGHAEILIKEMGKVKKGEGSWEKGLDVMKSE
CCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCHHHHHHHHHHH
LKSFGLNPDELIARDGSGVSHINGVSAGQIGELLYAVQKEKWYPAFLRSLPVAGASDRMT
HHHCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCC
GGTLRNRLKGTPAEGKIKAKTGSLTSVSSIAGYADTKTGDTLIFSVLQNGLLDEDDGKDI
CHHHHHHHCCCCCCCEEEECCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
EDKIAVVLANQ
CCEEEEEEECC
>Mature Secondary Structure
MKTYVKRLSAVILLLIIAAVPYIDDAAKAAEQKNTLQKELEHILDEEPTLKGASAGVSVR
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
SAKTGEVLFGSREDMRLRPASLMKLLTASAALSVLGEDYTFKTEVRADGAVKGKQLRGNL
CCCCCCEEECCCCCCEECHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECEE
YLRGKGDPTLLVSDFEKMAKQVKARGIHVIKGDLVGDDSWYDDTRYSVDLPWSDEGQYYG
EEEECCCCEEEHHHHHHHHHHHHHCCEEEEECCEECCCCCCCCCCEEEECCCCCCCCEEC
AQVSALTASPNEDYDTGTVIAEISPAKQPGKKPRISISPHTDVVRVKNEVKTVASDEKKD
EEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCC
LTVEREHGGNVITIKGTIPAGSAQAREWAAVWDPSSYALDLWKQALTKQGITVKGKIRTG
CEEEECCCCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECC
RMPHRTQLVTSRTSMPLSELLIPFMKLSNNGHAEILIKEMGKVKKGEGSWEKGLDVMKSE
CCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCHHHHHHHHHHH
LKSFGLNPDELIARDGSGVSHINGVSAGQIGELLYAVQKEKWYPAFLRSLPVAGASDRMT
HHHCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCC
GGTLRNRLKGTPAEGKIKAKTGSLTSVSSIAGYADTKTGDTLIFSVLQNGLLDEDDGKDI
CHHHHHHHCCCCCCCEEEECCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
EDKIAVVLANQ
CCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7711903; 9384377 [H]