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The map label for this gene is fenC [H]

Identifier: 154686277

GI number: 154686277

Start: 1945951

End: 1953600

Strand: Reverse

Name: fenC [H]

Synonym: RBAM_018440

Alternate gene names: 154686277

Gene position: 1953600-1945951 (Counterclockwise)

Preceding gene: 154686278

Following gene: 154686276

Centisome position: 49.85

GC content: 51.67

Gene sequence:

>7650_bases
ATGGGGCAGCAACCGGAAATACAAGATATATATCCTTTATCTTTTATGCAGGAGGGCATGCTTTTTCATTCTCTGTTGGA
TCATGACTCAAGAGCCTACTTCGAACAAGCGGTGTTTACGATCAGCGGACAGCTTGACCGGGAACGATTCCAAAAAAGTA
TAGATGCTGTTTTTGAACGATACGATATTTTCCGTACGACATTTATTCATAAGAATGTGGCGAAGCCCCGCCAAGTCGTG
TTGAAAAACAGGCCGAGCCGCGTTCAGTTTCATGATATTTCTCATTTGGACGAGAAGGCACAAGATAAATATGCCGACCG
ATTCAGAAAGGAAGATAAAGATAAAGGCTTTGATTTGCAATCAGACCCTCTCATGAGAGTCTCCATTTTGAAAAAAGGGC
CTGAACGCTATGTTTGTATATGGAGCCATCATCATATCGTCATGGACGGCTGGTGCTTCGGGATTGTCATGAAGGAATTT
CTGATGATCTATCAATCTCTCGGAGACGGGTGGCTCCCGTCTCTCGAGCCTGTTCAGCCATATGGTAAGTATATTAAATG
GCTCATGAAGCAGGATCGTAAAGAAGCCGAGATTTTTTGGAAAACGAGACTTGCCGATCTTGAGCAATCGGCGTCTCTTC
CGAAAAAATCCGCGGAACCAAATGGCGAACTTGAGCAGGCGGTTTTCACCATTTCTGAAGAGCAGACAAATGAGCTGAAG
AACATTGCGGCAAGGGCGGGAGCAACGCTGAATACAGTGTTCCAGGCACTGTGGGGCATTTTGCTCCAGCGTGTCAGCCG
CTGTGATGACGCCGTTTTCGGTTCTGTCGTTTCCGGCCGGCCGTCGGATCTCACAGGCGTGGAAAAAATGGTGGGGCTGT
TTATTAATACGATTCCCGTGCGGGTGAAAAGCGGTTCATTTTCTTTTCTGGAGCTCGTCAGGCATTTGCAGCAGGAGACG
CTGCAAGCAGAAGCGTACAGCTATTATCCGCTGTATGACATTCAGGCGCAAAGCCCTTTGAAGCAAGCGCTGTTTGACCA
CATTATCGTGTTTGAAAATGTGCCGGCCCAGCGTGAAATTGAAAATGTGAGTCAGGCCGGTTCATTTGATTTTGCGGTAG
AAGATTTCACGATGGAGGAAGTCACAAACTACGGATGCAGCATAAAGGTGATTCCGGGAAATTCTCTTTATATCCGCTTA
AACTTTGATACCGGTATATACGATCGTATTTTTATGAAGAATATTGAAACATTTTTACGGCATATGATGAATTCAGTCAT
CTCCGATCCTGAAATTTGCGCCTCCGAGATCGCATTGCTTGATGCGTGTGAAGCCAGAAGTATGCTTGATGCGTTTAACC
GTACAGAAACGGTTGAACCGCCGGCTCCGACGCTTCACGGGCTGTTTGCCCGCCGTGCCGCGCTTTCGCCGCATCGTCCG
GCGCTCCGTTTTCCGGGCGGCATGCTGACGTACGCCGAGCTTGACCAGTACACAGACAGACTCGCTGTTCGGCTCCGCCA
AAAAGGCGTCCGCAAAGAAAGCATGGTCGGCGTACTCGCTGAACGCTCGCCGGAGATGGTGGTTTCTGTGCTTGCCGTGT
TAAAAGCGGGCGGCGCCTACGTGCCGCTTGACCCGGAGTATCCTGAGGACAGGCTGCGCTATATGCTCGACGACTGCGGC
GCTTGTCTTCTGCTCGCACAGCCGGGGTTATCCGTTTCCGGTTTTTCCGGAGAAACGCTAGAAGTGTCTCTTTCTGCTCT
GACAAGTGAGGCGGAGACAGGGGCTGTCTCTGAAGAAGCGGATGCTGATTCGCTCGCTTATATCATTTATACGTCCGGTT
CGACGGGAACACCGAAGGGAGTAGCTGTTGAACACCGTCAGGCCGCCGCCTTTTTATCAGGGATGCAAGGGCAGTTCCCG
TTGACAGAAGAGGATATTATCGTGCTGAAATCATCCTTTTCTTTCGACGCCTCCATCTGGCAATTGTTTTGGTGGACGAT
GTCCGGCGCCTCCGTGTATCTGCTTCCGGCCGGCTGGGAGAAAGATCCTGTGCGGATGATTGAAGCGTTTGCCTCAGAAA
AGGTGACGACCGCGCATTTTATTCCGGCGATGGTCAACAGCTTTTTAGACGCGCTGGAAACAGAGCCTGCGGAAACAAGA
ACACGCCTCGGCAGAACCTTGACACGCGTGTTTGCCGGAGGGGAAGCTCTTTCACCGCTTACGGCTGCCCGGTTTGCCGA
TCTTCTGCCGGAGACCGTGCTTATTCACGGCTACGGGCCGACGGAAGCGACGGTTGATGCGGCGTTTTACGTCTGTGACC
GAAAACGGGACAGCGGACGGACGCGGCTTCCGATCGGAAAACCCGTTCCGGGTGCCCGTCTGTATGTATTAGATAGCGGA
GGAACCATCCAGCCTGCGGGCGTGGCAGGAGAGCTGTACATCGCGGGGACAGGGGTGGCCCGGGGCTATCTGAACCGGCC
TGAGCTGACGGAGGAGCGTTTTCTCGATGATCCGTTTTATCCGGGAGAGCGCATGTATCAGACGGGCGATATCGCACGCT
GGACAGAAGACGGCCTTGTCGAATGGCTAGGACGTTCAGACGGACAGGTGAAAGTCCGCGGCTACCGGATTGAACCGGGA
GAGATCGAAGCGGCGATCCGGCGCATCGACGGCATTCGTGAGGCGGCGGTCACCGCCCGGAACGAACACGGCGAAACCGC
GCTTTACGCCTATATTGACGGACGGGAAAGCGATGACGTGCGGGCGGAGCTTGCGACACGCCTTCCGGCTTACATGATGC
CAGCTCAGTTCATAAAGATGACCGAATGGCCGGTCACACCGAGCGGAAAGCTTGACCGCCGCGCGCTGCCGGCTCCCGGC
GGAGCGGCAGACAGACAGGCGTACACCGCCCCGCGGAACGTCACGGAAATGAAGCTTTGCGCCCTTTGGGAAGAGGTGCT
GAAAAACGGCCCCGTCGGCATCCGGGATCACTTTTTTGAGCGGGGCGGCCATTCGTTAAAAGCGACGGCTCTTGTCTCCC
GCATCGCCAAAGAGTTCGGTGTTCAGGTGCCGTTACAAGACATCTTCGCCCGGCCGACGGTGGAAGAGCTCGCTTCGGTC
ATTCAGGACTTGGAAGAGAGCCCGTATGAAGCGATTCAGCCTGCGCAAACACAGGACACCTACCCGGTGTCTTCGGCGCA
GAAACGGATGTATGTGCTCCAGCAGCTTGAAGACGGCGGTGTCGGCTACAATATGCCGGCTGTGCTGGAACTGACGGGCC
CGCTTGACCGCGGCCGGCTGGAGGAGACGTTCCGGCAGCTTGTTGAGCGGCATGAGTCGCTCAGAACGTCCTTTGAAACG
GGGCCTGACGGCGAACCGGTGCAGCGCATCCATGACAGCGTACCGTTTCAGCTGGATGAGGCCGGGTCAGCTGACGCATT
CGTCCGGCCGTTTTGTCTGGAGGAAGCGCCGCTCTTCCGTGCGGCCCTCGTGAAAGAATCGGACGAACGTCATCTTTTAT
TAACGGATATGCATCATATTATTTCTGACGGTGTGTCCGTCAACACCTTGATTAAAGAATTCGGCGAGCTGTACGCAGGC
CGTTCGCTTGCGCCAATGCGCCTTCAATATAAAGACTATGCCGTCTGGCAGCGGTCGTTTCAGGAGAAAGAAGGGTACCA
GAAGCAGGAAGCCTACTGGCTGAAGCGGCTAGAAGGAGAGCTTCCGGTGCTTGAACTTCCGGCTGACAAGCCCCGTCCGG
CTGTCAGAAGCTTTGCGGGCGGCAGCGTATCGTGCACGCTTGACGCTGAAACGGCATCCGGCCTTCACCGCATTGCCCGG
GATCACGGCTCCACTTTGTATATGGTGCTTCTCGCCGCGTACAATACGTTACTCGCGCGCCTGAGCGGGCAGGAAGACAT
CATCGTCGGCTCGCCGATTGCCGGGCGTCCGCACAAAGACCTTGAACCGATTCTCGGCATGTTCGTCAACACGCTCGCCA
TCAGAACGGAGCCGAAAGGAGACAAACGGTTTACCGATTACTTGGCGGAAGTCCGCCAGGCCGCGCTTGAGGCGTATGAG
CATCAGGACTATCCGTTTGAAGAGCTAGTGGAACGGCTCGGTGTGCAGCGGGACATGAGCCGAAATCCGCTGTTTGATGT
GATGTTTGTGCTCCAAAATATGGAGCGTGAATCCCTGGTGTTAAATAAGCTGCATTTGGCTCAAGCTGCGGATACAAGTC
ATAAAACCGCAAAGTTTGATGCCACGCTTTACGCGTCAGAAGGGTCTGACGGTTCCATCAGCTTTGATTTTGAATTCAAT
ACAGATGTCTATCAAAAACAGACAATTGAAAAATGGCTTTCTTATTTTACCCGTATTCTTACAAAAGTAATTGAAAACCA
AGCGATACCGCTTGGTGACATTCACGTACTGGATGATGCTGAAACAAATCGCGTCATTTATCAGTTTAATCAGACGAAAA
GCGATTACCCAAGACACGAAACCATCAGCCGTTTATTTGAGCGGCAGGCAAAAGAAACCCCCGATGCCCGGGCAGTTGTA
TATGATGGACAAATCTTGACATACCGTGAGCTGAACGAACGGGCTAACAGAATAGCGGCGGCTCTCCGATCAAATAGCGT
CGGTCCGGAAAGCGTTGTCGCATTATTAACCGGCCGCACAACAGAGCTTGCTTCCGGAATCCTCGGAATATTAAAAGCGG
GAGGCGCCTACTTGCCTATCGGTGACGATGTGCCGCGGGAACGGGCTGAATGGATGCTTAAAGACTGTAAAGCTGATATT
CTTCTCCAATCTGATAAACTTGACGGTCTGCCGCTTTCAGGAAAACGTTTATTCATAGAGGATATTCAAACAAAGGCCGG
ATTGAGTTCGGAAAATCCCGAACCGCTCGGCGGACCTGAATCATTGGCCTACATGATTTATACGTCCGGATCAACAGGTG
CGCCAAAAGGCGTCATGATTGAACAGCGAAGCGTGATCCGCCTTGTGAAAAACAGCAATTATATTGATTTTACGCCGGAA
GATAGACTGTTATTTACTTCATCATTAGGATTTGACGTTACAACATTTGAAATATTCGGTCCGCTTTTAAACGGCGCTTC
TTTATATGTAAGTGACCAGGAAACCTATCTCGACTCTGATGTTTTGGAAACATTTATACAGCAAAACGGCATTACGACAC
TGTGGCTGACATCGTCTCTGTTCAACCATTTATCAGAACAAAATGAACACGTGTTTTCCGGATTATCCCGATTGATTATC
GGCGGGGAAGCACTGTCCCCAAGCCATGTAAACCGGGTTCGGAATGCGCTGCCGCATCTCTCAGTATGGAATGGATACGG
ACCGACTGAAAACACGACGTTCTCGACTTACTTTTTGATTGAACAATCATACGATCATTCAATCCCGATCGGCCGCCCTG
TCGGAAATTCAACCGCATATATCATAAACAGCAGGGGAACACCGCAGCCGATCGGAGTCATCGGCGAATTATGCACAGGC
GGAGACGGTGTGGCAAGAGGATATTTCGGCCGCCCTGAGCTGACGGAAGAAAAATTTGTCCCTAATCCTTTTGTTCCCGG
AGAACGGATGTACCGCACCGGAGATTTAGCCCGCTGGCTGCCGGACGGAACGATCGAATATGCCGGGCGGATGGATGATC
AAGTGAAAATCCGCGGTTATCGGGTCGAGCTGGGAGAGATTGAAGCCGCACTGAGGAGCCTGGACGGCGTGAAAGAAGCT
GCCGTGTCAGTCAGAACCGGGCAGTCCGGCAATAAAGAACTGATCGCATATATGAGTCTGCAGGCGGACATGGATACAGA
AAAAGTGCGTTCTTTACTGTCTAAGCAACTGCCGAATTACATGGTTCCGGCCTATATGATGGAACTTGAGAAGCTGCCGC
TTACGCCGAACGGTAAATTGGATCGGAAAAATCTGCCCGAACCGGAGCTCGCGCTTCAAACCGCGTACACAGCTCCCCGC
AATGAGCTTGAAGAACAGCTTTCCGTGATCTGGCAGGAAGTGCTCGGCACAAAACAAGTCGGGATTGAGGACTCATTTTT
TGAGTTGGGCGGCGATTCAATCAAAGCGCTGCAAGTTTCCGCACGGCTCGGACGCTATGGGTGGAAAATGACGGCAAGCG
ACTTATTCCGGCATCCGTCCATTAAGGAGCTCGCGCCACTTATCCGGAAAGCGGAAAGAGTCATCGATCAGCGGCCGGTG
GAAGGAGACATACCTTGGACACCCGTTCAGCACTGGTTTTTATCACAGCGGATGGAAAACAGAAATCATTTCAATCAGTC
CGTCATGATGTTCAGCTCTGACGCATTGCATAAACAGCCGCTCAAAGAAGTCTTAGAGCATCTTGTCATTCATCATGATG
CACTCCGGATAACCGTCAGTGCAGAAAACGAAAGTTTCAGACAAATCAATCACGGTATTCAAAAAGATGAACTGTACAGC
TTGGACATTTGGGATCTGTCTGAGACAGATACTTGGGAAAAAGAAATAGAAAGTGAAGTCGCTGCGCTCCAACAGCGGAT
GGATATTGAAAAAGGCCCGTTATTAAAAGCCGGCTGGTTCAAAACCCGGTCCGGAGATTATTTATTCATCACCGTACATC
ACCTGGCGGTTGACGGAGTGTCATGGCGTATTTTGCTGGAGGATTTATCTGCCGCTTACACTCAAGCCGTAAAAGGTCAG
CCGGTCCAGCTTCCGCCAAAGACCGATTCGTTTAAGCAATACGCTGAAAGGCTTTCAGAATACGCAAAAAGCAGCAAGCT
GATGCGTGAAGAAGAATATTGGCGTTTTATTGAAGAAGAAACAGCCGCCGAACTTCCTTATGAAAAACCGCAGCATCAGA
CGGGAGCCGACAGCATTCGGCAAACGGTAAGCTTTACGCTTACAGAAGAAGAAACGTCCGTTTTGCTTCAGCAGGTCAAC
CGGGCCTACCATACCGATACGCAAGATATTCTTCTGACTGCCGCAGCTTTGGCTTTACGGGACTGGACAGGGGGCGGCAG
ACTGCGCATCGCGATGGAAGGGCACGGGAGAGAGCACATCATGCCGGAGCTCGACATCAGCCGCACCGTAGGCTGGTTTA
CCTCCATGTATCCGGTGCTCATTGACTTGAACACAGCAGGCGCTGAGCTTGGAACGGCGGTAAAAACGGTCAAAGACACA
CTCGGAAGAATACCGGATAAAGGAATAGGCTACGGCATTTTAAAATACATGACACCGCCTGAACAAAAAACAATCCGCTT
CAGACAAGCGCCTGAAATCAGCTTTAACTATTTAGGGCAATTCAATGATACAGAAGATCAGCACACGTTCAGTCTGTCCG
GTCTTGCAAGCGGGCACGACATCACGCCGACATGGCAGCGGGAACAAGCGGTGGAAATGAGCGCGATGGCCGCACAAAAC
AAACTTCACTTCAGTTTGAGCTATCCGCCGAGCCGCTTCCGCAAAGAAACAATGGAACAGCTGCTGCAAACTTTACAGCA
ATATTTGCGTGATATTATGGCGCACTGCACAGGCAAAGAGGAAGCAGAAAAAACCGTTAGTGATTTTAGCAGCAAAACGT
TAACATCTGATGATTTGGACAGCATAGCGAGTTTTGTCGAGGAACTGTAG

Upstream 100 bases:

>100_bases
TGAATGGAGCGCCGCTGATTTCAGTGACGAGGAGTTAACGCTGGAAGATCTGAGTGACATTATGGGAGCCGTCAACAAAC
TATAGAAAAGGAGTGGCGCA

Downstream 100 bases:

>100_bases
AAAAAGGCGACGGGGAGATTATAACATGACAAAAAAGAATGCAATTCAGGATATTTATCCGCTGTCTTATATGCAGGAAG
GAATGCTTTTTCATTCCCTC

Product: FenC

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Peptide synthase 3; ATP-dependent glutamate adenylase 2; GluA 2; Glutamate activase 2; ATP-dependent alanine/valine adenylase; Ala/ValA; Alanine/valine activase [H]

Number of amino acids: Translated: 2549; Mature: 2548

Protein sequence:

>2549_residues
MGQQPEIQDIYPLSFMQEGMLFHSLLDHDSRAYFEQAVFTISGQLDRERFQKSIDAVFERYDIFRTTFIHKNVAKPRQVV
LKNRPSRVQFHDISHLDEKAQDKYADRFRKEDKDKGFDLQSDPLMRVSILKKGPERYVCIWSHHHIVMDGWCFGIVMKEF
LMIYQSLGDGWLPSLEPVQPYGKYIKWLMKQDRKEAEIFWKTRLADLEQSASLPKKSAEPNGELEQAVFTISEEQTNELK
NIAARAGATLNTVFQALWGILLQRVSRCDDAVFGSVVSGRPSDLTGVEKMVGLFINTIPVRVKSGSFSFLELVRHLQQET
LQAEAYSYYPLYDIQAQSPLKQALFDHIIVFENVPAQREIENVSQAGSFDFAVEDFTMEEVTNYGCSIKVIPGNSLYIRL
NFDTGIYDRIFMKNIETFLRHMMNSVISDPEICASEIALLDACEARSMLDAFNRTETVEPPAPTLHGLFARRAALSPHRP
ALRFPGGMLTYAELDQYTDRLAVRLRQKGVRKESMVGVLAERSPEMVVSVLAVLKAGGAYVPLDPEYPEDRLRYMLDDCG
ACLLLAQPGLSVSGFSGETLEVSLSALTSEAETGAVSEEADADSLAYIIYTSGSTGTPKGVAVEHRQAAAFLSGMQGQFP
LTEEDIIVLKSSFSFDASIWQLFWWTMSGASVYLLPAGWEKDPVRMIEAFASEKVTTAHFIPAMVNSFLDALETEPAETR
TRLGRTLTRVFAGGEALSPLTAARFADLLPETVLIHGYGPTEATVDAAFYVCDRKRDSGRTRLPIGKPVPGARLYVLDSG
GTIQPAGVAGELYIAGTGVARGYLNRPELTEERFLDDPFYPGERMYQTGDIARWTEDGLVEWLGRSDGQVKVRGYRIEPG
EIEAAIRRIDGIREAAVTARNEHGETALYAYIDGRESDDVRAELATRLPAYMMPAQFIKMTEWPVTPSGKLDRRALPAPG
GAADRQAYTAPRNVTEMKLCALWEEVLKNGPVGIRDHFFERGGHSLKATALVSRIAKEFGVQVPLQDIFARPTVEELASV
IQDLEESPYEAIQPAQTQDTYPVSSAQKRMYVLQQLEDGGVGYNMPAVLELTGPLDRGRLEETFRQLVERHESLRTSFET
GPDGEPVQRIHDSVPFQLDEAGSADAFVRPFCLEEAPLFRAALVKESDERHLLLTDMHHIISDGVSVNTLIKEFGELYAG
RSLAPMRLQYKDYAVWQRSFQEKEGYQKQEAYWLKRLEGELPVLELPADKPRPAVRSFAGGSVSCTLDAETASGLHRIAR
DHGSTLYMVLLAAYNTLLARLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLAIRTEPKGDKRFTDYLAEVRQAALEAYE
HQDYPFEELVERLGVQRDMSRNPLFDVMFVLQNMERESLVLNKLHLAQAADTSHKTAKFDATLYASEGSDGSISFDFEFN
TDVYQKQTIEKWLSYFTRILTKVIENQAIPLGDIHVLDDAETNRVIYQFNQTKSDYPRHETISRLFERQAKETPDARAVV
YDGQILTYRELNERANRIAAALRSNSVGPESVVALLTGRTTELASGILGILKAGGAYLPIGDDVPRERAEWMLKDCKADI
LLQSDKLDGLPLSGKRLFIEDIQTKAGLSSENPEPLGGPESLAYMIYTSGSTGAPKGVMIEQRSVIRLVKNSNYIDFTPE
DRLLFTSSLGFDVTTFEIFGPLLNGASLYVSDQETYLDSDVLETFIQQNGITTLWLTSSLFNHLSEQNEHVFSGLSRLII
GGEALSPSHVNRVRNALPHLSVWNGYGPTENTTFSTYFLIEQSYDHSIPIGRPVGNSTAYIINSRGTPQPIGVIGELCTG
GDGVARGYFGRPELTEEKFVPNPFVPGERMYRTGDLARWLPDGTIEYAGRMDDQVKIRGYRVELGEIEAALRSLDGVKEA
AVSVRTGQSGNKELIAYMSLQADMDTEKVRSLLSKQLPNYMVPAYMMELEKLPLTPNGKLDRKNLPEPELALQTAYTAPR
NELEEQLSVIWQEVLGTKQVGIEDSFFELGGDSIKALQVSARLGRYGWKMTASDLFRHPSIKELAPLIRKAERVIDQRPV
EGDIPWTPVQHWFLSQRMENRNHFNQSVMMFSSDALHKQPLKEVLEHLVIHHDALRITVSAENESFRQINHGIQKDELYS
LDIWDLSETDTWEKEIESEVAALQQRMDIEKGPLLKAGWFKTRSGDYLFITVHHLAVDGVSWRILLEDLSAAYTQAVKGQ
PVQLPPKTDSFKQYAERLSEYAKSSKLMREEEYWRFIEEETAAELPYEKPQHQTGADSIRQTVSFTLTEEETSVLLQQVN
RAYHTDTQDILLTAAALALRDWTGGGRLRIAMEGHGREHIMPELDISRTVGWFTSMYPVLIDLNTAGAELGTAVKTVKDT
LGRIPDKGIGYGILKYMTPPEQKTIRFRQAPEISFNYLGQFNDTEDQHTFSLSGLASGHDITPTWQREQAVEMSAMAAQN
KLHFSLSYPPSRFRKETMEQLLQTLQQYLRDIMAHCTGKEEAEKTVSDFSSKTLTSDDLDSIASFVEEL

Sequences:

>Translated_2549_residues
MGQQPEIQDIYPLSFMQEGMLFHSLLDHDSRAYFEQAVFTISGQLDRERFQKSIDAVFERYDIFRTTFIHKNVAKPRQVV
LKNRPSRVQFHDISHLDEKAQDKYADRFRKEDKDKGFDLQSDPLMRVSILKKGPERYVCIWSHHHIVMDGWCFGIVMKEF
LMIYQSLGDGWLPSLEPVQPYGKYIKWLMKQDRKEAEIFWKTRLADLEQSASLPKKSAEPNGELEQAVFTISEEQTNELK
NIAARAGATLNTVFQALWGILLQRVSRCDDAVFGSVVSGRPSDLTGVEKMVGLFINTIPVRVKSGSFSFLELVRHLQQET
LQAEAYSYYPLYDIQAQSPLKQALFDHIIVFENVPAQREIENVSQAGSFDFAVEDFTMEEVTNYGCSIKVIPGNSLYIRL
NFDTGIYDRIFMKNIETFLRHMMNSVISDPEICASEIALLDACEARSMLDAFNRTETVEPPAPTLHGLFARRAALSPHRP
ALRFPGGMLTYAELDQYTDRLAVRLRQKGVRKESMVGVLAERSPEMVVSVLAVLKAGGAYVPLDPEYPEDRLRYMLDDCG
ACLLLAQPGLSVSGFSGETLEVSLSALTSEAETGAVSEEADADSLAYIIYTSGSTGTPKGVAVEHRQAAAFLSGMQGQFP
LTEEDIIVLKSSFSFDASIWQLFWWTMSGASVYLLPAGWEKDPVRMIEAFASEKVTTAHFIPAMVNSFLDALETEPAETR
TRLGRTLTRVFAGGEALSPLTAARFADLLPETVLIHGYGPTEATVDAAFYVCDRKRDSGRTRLPIGKPVPGARLYVLDSG
GTIQPAGVAGELYIAGTGVARGYLNRPELTEERFLDDPFYPGERMYQTGDIARWTEDGLVEWLGRSDGQVKVRGYRIEPG
EIEAAIRRIDGIREAAVTARNEHGETALYAYIDGRESDDVRAELATRLPAYMMPAQFIKMTEWPVTPSGKLDRRALPAPG
GAADRQAYTAPRNVTEMKLCALWEEVLKNGPVGIRDHFFERGGHSLKATALVSRIAKEFGVQVPLQDIFARPTVEELASV
IQDLEESPYEAIQPAQTQDTYPVSSAQKRMYVLQQLEDGGVGYNMPAVLELTGPLDRGRLEETFRQLVERHESLRTSFET
GPDGEPVQRIHDSVPFQLDEAGSADAFVRPFCLEEAPLFRAALVKESDERHLLLTDMHHIISDGVSVNTLIKEFGELYAG
RSLAPMRLQYKDYAVWQRSFQEKEGYQKQEAYWLKRLEGELPVLELPADKPRPAVRSFAGGSVSCTLDAETASGLHRIAR
DHGSTLYMVLLAAYNTLLARLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLAIRTEPKGDKRFTDYLAEVRQAALEAYE
HQDYPFEELVERLGVQRDMSRNPLFDVMFVLQNMERESLVLNKLHLAQAADTSHKTAKFDATLYASEGSDGSISFDFEFN
TDVYQKQTIEKWLSYFTRILTKVIENQAIPLGDIHVLDDAETNRVIYQFNQTKSDYPRHETISRLFERQAKETPDARAVV
YDGQILTYRELNERANRIAAALRSNSVGPESVVALLTGRTTELASGILGILKAGGAYLPIGDDVPRERAEWMLKDCKADI
LLQSDKLDGLPLSGKRLFIEDIQTKAGLSSENPEPLGGPESLAYMIYTSGSTGAPKGVMIEQRSVIRLVKNSNYIDFTPE
DRLLFTSSLGFDVTTFEIFGPLLNGASLYVSDQETYLDSDVLETFIQQNGITTLWLTSSLFNHLSEQNEHVFSGLSRLII
GGEALSPSHVNRVRNALPHLSVWNGYGPTENTTFSTYFLIEQSYDHSIPIGRPVGNSTAYIINSRGTPQPIGVIGELCTG
GDGVARGYFGRPELTEEKFVPNPFVPGERMYRTGDLARWLPDGTIEYAGRMDDQVKIRGYRVELGEIEAALRSLDGVKEA
AVSVRTGQSGNKELIAYMSLQADMDTEKVRSLLSKQLPNYMVPAYMMELEKLPLTPNGKLDRKNLPEPELALQTAYTAPR
NELEEQLSVIWQEVLGTKQVGIEDSFFELGGDSIKALQVSARLGRYGWKMTASDLFRHPSIKELAPLIRKAERVIDQRPV
EGDIPWTPVQHWFLSQRMENRNHFNQSVMMFSSDALHKQPLKEVLEHLVIHHDALRITVSAENESFRQINHGIQKDELYS
LDIWDLSETDTWEKEIESEVAALQQRMDIEKGPLLKAGWFKTRSGDYLFITVHHLAVDGVSWRILLEDLSAAYTQAVKGQ
PVQLPPKTDSFKQYAERLSEYAKSSKLMREEEYWRFIEEETAAELPYEKPQHQTGADSIRQTVSFTLTEEETSVLLQQVN
RAYHTDTQDILLTAAALALRDWTGGGRLRIAMEGHGREHIMPELDISRTVGWFTSMYPVLIDLNTAGAELGTAVKTVKDT
LGRIPDKGIGYGILKYMTPPEQKTIRFRQAPEISFNYLGQFNDTEDQHTFSLSGLASGHDITPTWQREQAVEMSAMAAQN
KLHFSLSYPPSRFRKETMEQLLQTLQQYLRDIMAHCTGKEEAEKTVSDFSSKTLTSDDLDSIASFVEEL
>Mature_2548_residues
GQQPEIQDIYPLSFMQEGMLFHSLLDHDSRAYFEQAVFTISGQLDRERFQKSIDAVFERYDIFRTTFIHKNVAKPRQVVL
KNRPSRVQFHDISHLDEKAQDKYADRFRKEDKDKGFDLQSDPLMRVSILKKGPERYVCIWSHHHIVMDGWCFGIVMKEFL
MIYQSLGDGWLPSLEPVQPYGKYIKWLMKQDRKEAEIFWKTRLADLEQSASLPKKSAEPNGELEQAVFTISEEQTNELKN
IAARAGATLNTVFQALWGILLQRVSRCDDAVFGSVVSGRPSDLTGVEKMVGLFINTIPVRVKSGSFSFLELVRHLQQETL
QAEAYSYYPLYDIQAQSPLKQALFDHIIVFENVPAQREIENVSQAGSFDFAVEDFTMEEVTNYGCSIKVIPGNSLYIRLN
FDTGIYDRIFMKNIETFLRHMMNSVISDPEICASEIALLDACEARSMLDAFNRTETVEPPAPTLHGLFARRAALSPHRPA
LRFPGGMLTYAELDQYTDRLAVRLRQKGVRKESMVGVLAERSPEMVVSVLAVLKAGGAYVPLDPEYPEDRLRYMLDDCGA
CLLLAQPGLSVSGFSGETLEVSLSALTSEAETGAVSEEADADSLAYIIYTSGSTGTPKGVAVEHRQAAAFLSGMQGQFPL
TEEDIIVLKSSFSFDASIWQLFWWTMSGASVYLLPAGWEKDPVRMIEAFASEKVTTAHFIPAMVNSFLDALETEPAETRT
RLGRTLTRVFAGGEALSPLTAARFADLLPETVLIHGYGPTEATVDAAFYVCDRKRDSGRTRLPIGKPVPGARLYVLDSGG
TIQPAGVAGELYIAGTGVARGYLNRPELTEERFLDDPFYPGERMYQTGDIARWTEDGLVEWLGRSDGQVKVRGYRIEPGE
IEAAIRRIDGIREAAVTARNEHGETALYAYIDGRESDDVRAELATRLPAYMMPAQFIKMTEWPVTPSGKLDRRALPAPGG
AADRQAYTAPRNVTEMKLCALWEEVLKNGPVGIRDHFFERGGHSLKATALVSRIAKEFGVQVPLQDIFARPTVEELASVI
QDLEESPYEAIQPAQTQDTYPVSSAQKRMYVLQQLEDGGVGYNMPAVLELTGPLDRGRLEETFRQLVERHESLRTSFETG
PDGEPVQRIHDSVPFQLDEAGSADAFVRPFCLEEAPLFRAALVKESDERHLLLTDMHHIISDGVSVNTLIKEFGELYAGR
SLAPMRLQYKDYAVWQRSFQEKEGYQKQEAYWLKRLEGELPVLELPADKPRPAVRSFAGGSVSCTLDAETASGLHRIARD
HGSTLYMVLLAAYNTLLARLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLAIRTEPKGDKRFTDYLAEVRQAALEAYEH
QDYPFEELVERLGVQRDMSRNPLFDVMFVLQNMERESLVLNKLHLAQAADTSHKTAKFDATLYASEGSDGSISFDFEFNT
DVYQKQTIEKWLSYFTRILTKVIENQAIPLGDIHVLDDAETNRVIYQFNQTKSDYPRHETISRLFERQAKETPDARAVVY
DGQILTYRELNERANRIAAALRSNSVGPESVVALLTGRTTELASGILGILKAGGAYLPIGDDVPRERAEWMLKDCKADIL
LQSDKLDGLPLSGKRLFIEDIQTKAGLSSENPEPLGGPESLAYMIYTSGSTGAPKGVMIEQRSVIRLVKNSNYIDFTPED
RLLFTSSLGFDVTTFEIFGPLLNGASLYVSDQETYLDSDVLETFIQQNGITTLWLTSSLFNHLSEQNEHVFSGLSRLIIG
GEALSPSHVNRVRNALPHLSVWNGYGPTENTTFSTYFLIEQSYDHSIPIGRPVGNSTAYIINSRGTPQPIGVIGELCTGG
DGVARGYFGRPELTEEKFVPNPFVPGERMYRTGDLARWLPDGTIEYAGRMDDQVKIRGYRVELGEIEAALRSLDGVKEAA
VSVRTGQSGNKELIAYMSLQADMDTEKVRSLLSKQLPNYMVPAYMMELEKLPLTPNGKLDRKNLPEPELALQTAYTAPRN
ELEEQLSVIWQEVLGTKQVGIEDSFFELGGDSIKALQVSARLGRYGWKMTASDLFRHPSIKELAPLIRKAERVIDQRPVE
GDIPWTPVQHWFLSQRMENRNHFNQSVMMFSSDALHKQPLKEVLEHLVIHHDALRITVSAENESFRQINHGIQKDELYSL
DIWDLSETDTWEKEIESEVAALQQRMDIEKGPLLKAGWFKTRSGDYLFITVHHLAVDGVSWRILLEDLSAAYTQAVKGQP
VQLPPKTDSFKQYAERLSEYAKSSKLMREEEYWRFIEEETAAELPYEKPQHQTGADSIRQTVSFTLTEEETSVLLQQVNR
AYHTDTQDILLTAAALALRDWTGGGRLRIAMEGHGREHIMPELDISRTVGWFTSMYPVLIDLNTAGAELGTAVKTVKDTL
GRIPDKGIGYGILKYMTPPEQKTIRFRQAPEISFNYLGQFNDTEDQHTFSLSGLASGHDITPTWQREQAVEMSAMAAQNK
LHFSLSYPPSRFRKETMEQLLQTLQQYLRDIMAHCTGKEEAEKTVSDFSSKTLTSDDLDSIASFVEEL

Specific function: This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Glu and Ala/Val as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Ala/Val residue is further epimerized to the D-isomer form. The activation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=660, Percent_Identity=25.3030303030303, Blast_Score=140, Evalue=1e-32,
Organism=Homo sapiens, GI187761345, Length=542, Percent_Identity=25.830258302583, Blast_Score=100, Evalue=2e-20,
Organism=Homo sapiens, GI187761343, Length=542, Percent_Identity=25.830258302583, Blast_Score=100, Evalue=2e-20,
Organism=Homo sapiens, GI156151445, Length=522, Percent_Identity=24.7126436781609, Blast_Score=98, Evalue=1e-19,
Organism=Homo sapiens, GI38505220, Length=530, Percent_Identity=25.2830188679245, Blast_Score=94, Evalue=2e-18,
Organism=Homo sapiens, GI42544132, Length=499, Percent_Identity=21.8436873747495, Blast_Score=86, Evalue=6e-16,
Organism=Homo sapiens, GI122937307, Length=486, Percent_Identity=24.4855967078189, Blast_Score=72, Evalue=6e-12,
Organism=Escherichia coli, GI1786801, Length=1101, Percent_Identity=28.2470481380563, Blast_Score=340, Evalue=9e-94,
Organism=Escherichia coli, GI1788107, Length=546, Percent_Identity=23.2600732600733, Blast_Score=108, Evalue=5e-24,
Organism=Escherichia coli, GI145693145, Length=504, Percent_Identity=24.8015873015873, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1786810, Length=509, Percent_Identity=24.3614931237721, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1790505, Length=547, Percent_Identity=22.4862888482633, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI1789201, Length=357, Percent_Identity=26.6106442577031, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17550940, Length=1158, Percent_Identity=23.0569948186528, Blast_Score=211, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17556356, Length=1250, Percent_Identity=24.08, Blast_Score=161, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71994703, Length=524, Percent_Identity=23.8549618320611, Blast_Score=103, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71994694, Length=524, Percent_Identity=23.8549618320611, Blast_Score=102, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71994690, Length=524, Percent_Identity=23.8549618320611, Blast_Score=102, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32564422, Length=409, Percent_Identity=25.4278728606357, Blast_Score=96, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32564420, Length=409, Percent_Identity=25.4278728606357, Blast_Score=96, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71996755, Length=460, Percent_Identity=23.2608695652174, Blast_Score=92, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17557194, Length=536, Percent_Identity=22.2014925373134, Blast_Score=88, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17531443, Length=541, Percent_Identity=22.181146025878, Blast_Score=85, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17538037, Length=511, Percent_Identity=22.8962818003914, Blast_Score=85, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17560308, Length=428, Percent_Identity=25.4672897196262, Blast_Score=80, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71983001, Length=539, Percent_Identity=21.8923933209648, Blast_Score=80, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982997, Length=539, Percent_Identity=21.8923933209648, Blast_Score=79, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560140, Length=497, Percent_Identity=22.5352112676056, Blast_Score=74, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17559526, Length=372, Percent_Identity=22.0430107526882, Blast_Score=68, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=971, Percent_Identity=25.5406797116375, Blast_Score=237, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6319699, Length=499, Percent_Identity=21.6432865731463, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648676, Length=645, Percent_Identity=30.5426356589147, Blast_Score=212, Evalue=3e-54,
Organism=Drosophila melanogaster, GI18859661, Length=517, Percent_Identity=24.9516441005803, Blast_Score=118, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24582852, Length=691, Percent_Identity=25.0361794500724, Blast_Score=104, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21356947, Length=500, Percent_Identity=21.8, Blast_Score=92, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21355181, Length=490, Percent_Identity=24.0816326530612, Blast_Score=87, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24581924, Length=378, Percent_Identity=25.1322751322751, Blast_Score=87, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24648260, Length=437, Percent_Identity=23.1121281464531, Blast_Score=86, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19922652, Length=506, Percent_Identity=23.3201581027668, Blast_Score=84, Evalue=2e-15,
Organism=Drosophila melanogaster, GI161076582, Length=504, Percent_Identity=20.6349206349206, Blast_Score=83, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24653035, Length=471, Percent_Identity=20.3821656050955, Blast_Score=78, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21358303, Length=447, Percent_Identity=23.9373601789709, Blast_Score=71, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 286297; Mature: 286165

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQQPEIQDIYPLSFMQEGMLFHSLLDHDSRAYFEQAVFTISGQLDRERFQKSIDAVFER
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
YDIFRTTFIHKNVAKPRQVVLKNRPSRVQFHDISHLDEKAQDKYADRFRKEDKDKGFDLQ
HHHHHHHHHHHCCCCHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SDPLMRVSILKKGPERYVCIWSHHHIVMDGWCFGIVMKEFLMIYQSLGDGWLPSLEPVQP
CCCCHHHHHHHCCCCCEEEEEECCEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
YGKYIKWLMKQDRKEAEIFWKTRLADLEQSASLPKKSAEPNGELEQAVFTISEEQTNELK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCHHHHHHHH
NIAARAGATLNTVFQALWGILLQRVSRCDDAVFGSVVSGRPSDLTGVEKMVGLFINTIPV
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEE
RVKSGSFSFLELVRHLQQETLQAEAYSYYPLYDIQAQSPLKQALFDHIIVFENVPAQREI
EEECCCHHHHHHHHHHHHHHHHHHHEEECCEEECCCCCHHHHHHHHHEEHCCCCCCHHHH
ENVSQAGSFDFAVEDFTMEEVTNYGCSIKVIPGNSLYIRLNFDTGIYDRIFMKNIETFLR
HHHHHCCCCCEEEHHCCHHHHHCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHH
HMMNSVISDPEICASEIALLDACEARSMLDAFNRTETVEPPAPTLHGLFARRAALSPHRP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCC
ALRFPGGMLTYAELDQYTDRLAVRLRQKGVRKESMVGVLAERSPEMVVSVLAVLKAGGAY
CCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
VPLDPEYPEDRLRYMLDDCGACLLLAQPGLSVSGFSGETLEVSLSALTSEAETGAVSEEA
CCCCCCCCHHHHHHHHHHCCCEEEEECCCCEECCCCCCEEEEEHHHHHHHHHCCCCCCCC
DADSLAYIIYTSGSTGTPKGVAVEHRQAAAFLSGMQGQFPLTEEDIIVLKSSFSFDASIW
CCCCEEEEEEECCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHH
QLFWWTMSGASVYLLPAGWEKDPVRMIEAFASEKVTTAHFIPAMVNSFLDALETEPAETR
HHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
TRLGRTLTRVFAGGEALSPLTAARFADLLPETVLIHGYGPTEATVDAAFYVCDRKRDSGR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHEEEEECCCCCCC
TRLPIGKPVPGARLYVLDSGGTIQPAGVAGELYIAGTGVARGYLNRPELTEERFLDDPFY
CCCCCCCCCCCCEEEEECCCCEECCCCCCEEEEEEECCHHHCCCCCCCCCHHHHCCCCCC
PGERMYQTGDIARWTEDGLVEWLGRSDGQVKVRGYRIEPGEIEAAIRRIDGIREAAVTAR
CCCHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHC
NEHGETALYAYIDGRESDDVRAELATRLPAYMMPAQFIKMTEWPVTPSGKLDRRALPAPG
CCCCCEEEEEEECCCCCCHHHHHHHHHCCHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCC
GAADRQAYTAPRNVTEMKLCALWEEVLKNGPVGIRDHFFERGGHSLKATALVSRIAKEFG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHC
VQVPLQDIFARPTVEELASVIQDLEESPYEAIQPAQTQDTYPVSSAQKRMYVLQQLEDGG
CCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
VGYNMPAVLELTGPLDRGRLEETFRQLVERHESLRTSFETGPDGEPVQRIHDSVPFQLDE
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEECC
AGSADAFVRPFCLEEAPLFRAALVKESDERHLLLTDMHHIISDGVSVNTLIKEFGELYAG
CCCCCHHHCCHHCCCCCHHHHHHHCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHCC
RSLAPMRLQYKDYAVWQRSFQEKEGYQKQEAYWLKRLEGELPVLELPADKPRPAVRSFAG
CCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHCCC
GSVSCTLDAETASGLHRIARDHGSTLYMVLLAAYNTLLARLSGQEDIIVGSPIAGRPHKD
CCEEEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCH
LEPILGMFVNTLAIRTEPKGDKRFTDYLAEVRQAALEAYEHQDYPFEELVERLGVQRDMS
HHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC
RNPLFDVMFVLQNMERESLVLNKLHLAQAADTSHKTAKFDATLYASEGSDGSISFDFEFN
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCEEEEEEEC
TDVYQKQTIEKWLSYFTRILTKVIENQAIPLGDIHVLDDAETNRVIYQFNQTKSDYPRHE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCHH
TISRLFERQAKETPDARAVVYDGQILTYRELNERANRIAAALRSNSVGPESVVALLTGRT
HHHHHHHHHHHCCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCH
TELASGILGILKAGGAYLPIGDDVPRERAEWMLKDCKADILLQSDKLDGLPLSGKRLFIE
HHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCHHEEEECCCCCCCCCCCCEEEHH
DIQTKAGLSSENPEPLGGPESLAYMIYTSGSTGAPKGVMIEQRSVIRLVKNSNYIDFTPE
HHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEECHHHHHHHHHCCCEEEECCC
DRLLFTSSLGFDVTTFEIFGPLLNGASLYVSDQETYLDSDVLETFIQQNGITTLWLTSSL
CCEEEEECCCCCEEHHHHHHHHHCCCEEEECCCHHHCCHHHHHHHHHHCCCEEEEHHHHH
FNHLSEQNEHVFSGLSRLIIGGEALSPSHVNRVRNALPHLSVWNGYGPTENTTFSTYFLI
HHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCEEEEEEEE
EQSYDHSIPIGRPVGNSTAYIINSRGTPQPIGVIGELCTGGDGVARGYFGRPELTEEKFV
EECCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PNPFVPGERMYRTGDLARWLPDGTIEYAGRMDDQVKIRGYRVELGEIEAALRSLDGVKEA
CCCCCCCCHHHHCCCHHHHCCCCCCHHCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHH
AVSVRTGQSGNKELIAYMSLQADMDTEKVRSLLSKQLPNYMVPAYMMELEKLPLTPNGKL
HHEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
DRKNLPEPELALQTAYTAPRNELEEQLSVIWQEVLGTKQVGIEDSFFELGGDSIKALQVS
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHCCCCCHHHHCCCCCCHHHHHH
ARLGRYGWKMTASDLFRHPSIKELAPLIRKAERVIDQRPVEGDIPWTPVQHWFLSQRMEN
HHHHHCCCEECHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
RNHFNQSVMMFSSDALHKQPLKEVLEHLVIHHDALRITVSAENESFRQINHGIQKDELYS
HHHHCHHHEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHCCCCCCCEEE
LDIWDLSETDTWEKEIESEVAALQQRMDIEKGPLLKAGWFKTRSGDYLFITVHHLAVDGV
EEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCEECCCCCEEEEEEEEEHCCCC
SWRILLEDLSAAYTQAVKGQPVQLPPKTDSFKQYAERLSEYAKSSKLMREEEYWRFIEEE
CHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAAELPYEKPQHQTGADSIRQTVSFTLTEEETSVLLQQVNRAYHTDTQDILLTAAALALR
HHHCCCCCCCCCCCCHHHHHHHHEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DWTGGGRLRIAMEGHGREHIMPELDISRTVGWFTSMYPVLIDLNTAGAELGTAVKTVKDT
CCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHH
LGRIPDKGIGYGILKYMTPPEQKTIRFRQAPEISFNYLGQFNDTEDQHTFSLSGLASGHD
HHCCCCCCCCCHHHHHCCCCHHHHEEECCCCCCCHHCCCCCCCCCCCCEEEEECCCCCCC
ITPTWQREQAVEMSAMAAQNKLHFSLSYPPSRFRKETMEQLLQTLQQYLRDIMAHCTGKE
CCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EAEKTVSDFSSKTLTSDDLDSIASFVEEL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHC
>Mature Secondary Structure 
GQQPEIQDIYPLSFMQEGMLFHSLLDHDSRAYFEQAVFTISGQLDRERFQKSIDAVFER
CCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
YDIFRTTFIHKNVAKPRQVVLKNRPSRVQFHDISHLDEKAQDKYADRFRKEDKDKGFDLQ
HHHHHHHHHHHCCCCHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SDPLMRVSILKKGPERYVCIWSHHHIVMDGWCFGIVMKEFLMIYQSLGDGWLPSLEPVQP
CCCCHHHHHHHCCCCCEEEEEECCEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
YGKYIKWLMKQDRKEAEIFWKTRLADLEQSASLPKKSAEPNGELEQAVFTISEEQTNELK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCHHHHHHHH
NIAARAGATLNTVFQALWGILLQRVSRCDDAVFGSVVSGRPSDLTGVEKMVGLFINTIPV
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEE
RVKSGSFSFLELVRHLQQETLQAEAYSYYPLYDIQAQSPLKQALFDHIIVFENVPAQREI
EEECCCHHHHHHHHHHHHHHHHHHHEEECCEEECCCCCHHHHHHHHHEEHCCCCCCHHHH
ENVSQAGSFDFAVEDFTMEEVTNYGCSIKVIPGNSLYIRLNFDTGIYDRIFMKNIETFLR
HHHHHCCCCCEEEHHCCHHHHHCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHH
HMMNSVISDPEICASEIALLDACEARSMLDAFNRTETVEPPAPTLHGLFARRAALSPHRP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCC
ALRFPGGMLTYAELDQYTDRLAVRLRQKGVRKESMVGVLAERSPEMVVSVLAVLKAGGAY
CCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
VPLDPEYPEDRLRYMLDDCGACLLLAQPGLSVSGFSGETLEVSLSALTSEAETGAVSEEA
CCCCCCCCHHHHHHHHHHCCCEEEEECCCCEECCCCCCEEEEEHHHHHHHHHCCCCCCCC
DADSLAYIIYTSGSTGTPKGVAVEHRQAAAFLSGMQGQFPLTEEDIIVLKSSFSFDASIW
CCCCEEEEEEECCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHH
QLFWWTMSGASVYLLPAGWEKDPVRMIEAFASEKVTTAHFIPAMVNSFLDALETEPAETR
HHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
TRLGRTLTRVFAGGEALSPLTAARFADLLPETVLIHGYGPTEATVDAAFYVCDRKRDSGR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHEEEEECCCCCCC
TRLPIGKPVPGARLYVLDSGGTIQPAGVAGELYIAGTGVARGYLNRPELTEERFLDDPFY
CCCCCCCCCCCCEEEEECCCCEECCCCCCEEEEEEECCHHHCCCCCCCCCHHHHCCCCCC
PGERMYQTGDIARWTEDGLVEWLGRSDGQVKVRGYRIEPGEIEAAIRRIDGIREAAVTAR
CCCHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHC
NEHGETALYAYIDGRESDDVRAELATRLPAYMMPAQFIKMTEWPVTPSGKLDRRALPAPG
CCCCCEEEEEEECCCCCCHHHHHHHHHCCHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCC
GAADRQAYTAPRNVTEMKLCALWEEVLKNGPVGIRDHFFERGGHSLKATALVSRIAKEFG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHC
VQVPLQDIFARPTVEELASVIQDLEESPYEAIQPAQTQDTYPVSSAQKRMYVLQQLEDGG
CCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
VGYNMPAVLELTGPLDRGRLEETFRQLVERHESLRTSFETGPDGEPVQRIHDSVPFQLDE
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEECC
AGSADAFVRPFCLEEAPLFRAALVKESDERHLLLTDMHHIISDGVSVNTLIKEFGELYAG
CCCCCHHHCCHHCCCCCHHHHHHHCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHCC
RSLAPMRLQYKDYAVWQRSFQEKEGYQKQEAYWLKRLEGELPVLELPADKPRPAVRSFAG
CCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHCCC
GSVSCTLDAETASGLHRIARDHGSTLYMVLLAAYNTLLARLSGQEDIIVGSPIAGRPHKD
CCEEEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCH
LEPILGMFVNTLAIRTEPKGDKRFTDYLAEVRQAALEAYEHQDYPFEELVERLGVQRDMS
HHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC
RNPLFDVMFVLQNMERESLVLNKLHLAQAADTSHKTAKFDATLYASEGSDGSISFDFEFN
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCEEEEEEEC
TDVYQKQTIEKWLSYFTRILTKVIENQAIPLGDIHVLDDAETNRVIYQFNQTKSDYPRHE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCHH
TISRLFERQAKETPDARAVVYDGQILTYRELNERANRIAAALRSNSVGPESVVALLTGRT
HHHHHHHHHHHCCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCH
TELASGILGILKAGGAYLPIGDDVPRERAEWMLKDCKADILLQSDKLDGLPLSGKRLFIE
HHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCHHEEEECCCCCCCCCCCCEEEHH
DIQTKAGLSSENPEPLGGPESLAYMIYTSGSTGAPKGVMIEQRSVIRLVKNSNYIDFTPE
HHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEECHHHHHHHHHCCCEEEECCC
DRLLFTSSLGFDVTTFEIFGPLLNGASLYVSDQETYLDSDVLETFIQQNGITTLWLTSSL
CCEEEEECCCCCEEHHHHHHHHHCCCEEEECCCHHHCCHHHHHHHHHHCCCEEEEHHHHH
FNHLSEQNEHVFSGLSRLIIGGEALSPSHVNRVRNALPHLSVWNGYGPTENTTFSTYFLI
HHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCEEEEEEEE
EQSYDHSIPIGRPVGNSTAYIINSRGTPQPIGVIGELCTGGDGVARGYFGRPELTEEKFV
EECCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PNPFVPGERMYRTGDLARWLPDGTIEYAGRMDDQVKIRGYRVELGEIEAALRSLDGVKEA
CCCCCCCCHHHHCCCHHHHCCCCCCHHCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHH
AVSVRTGQSGNKELIAYMSLQADMDTEKVRSLLSKQLPNYMVPAYMMELEKLPLTPNGKL
HHEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
DRKNLPEPELALQTAYTAPRNELEEQLSVIWQEVLGTKQVGIEDSFFELGGDSIKALQVS
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHCCCCCHHHHCCCCCCHHHHHH
ARLGRYGWKMTASDLFRHPSIKELAPLIRKAERVIDQRPVEGDIPWTPVQHWFLSQRMEN
HHHHHCCCEECHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
RNHFNQSVMMFSSDALHKQPLKEVLEHLVIHHDALRITVSAENESFRQINHGIQKDELYS
HHHHCHHHEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHCCCCCCCEEE
LDIWDLSETDTWEKEIESEVAALQQRMDIEKGPLLKAGWFKTRSGDYLFITVHHLAVDGV
EEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCEECCCCCEEEEEEEEEHCCCC
SWRILLEDLSAAYTQAVKGQPVQLPPKTDSFKQYAERLSEYAKSSKLMREEEYWRFIEEE
CHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAAELPYEKPQHQTGADSIRQTVSFTLTEEETSVLLQQVNRAYHTDTQDILLTAAALALR
HHHCCCCCCCCCCCCHHHHHHHHEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DWTGGGRLRIAMEGHGREHIMPELDISRTVGWFTSMYPVLIDLNTAGAELGTAVKTVKDT
CCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHH
LGRIPDKGIGYGILKYMTPPEQKTIRFRQAPEISFNYLGQFNDTEDQHTFSLSGLASGHD
HHCCCCCCCCCHHHHHCCCCHHHHEEECCCCCCCHHCCCCCCCCCCCCEEEEECCCCCCC
ITPTWQREQAVEMSAMAAQNKLHFSLSYPPSRFRKETMEQLLQTLQQYLRDIMAHCTGKE
CCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EAEKTVSDFSSKTLTSDDLDSIASFVEEL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 7711903; 10471562 [H]