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The map label for this gene is fenB [H]

Identifier: 154686278

GI number: 154686278

Start: 1953616

End: 1961313

Strand: Reverse

Name: fenB [H]

Synonym: RBAM_018450

Alternate gene names: 154686278

Gene position: 1961313-1953616 (Counterclockwise)

Preceding gene: 154686279

Following gene: 154686277

Centisome position: 50.05

GC content: 49.77

Gene sequence:

>7698_bases
GTGACACAAGCGACAGAAATTCAAGATATTTACCCTTTATCATATATGCAGGAAGGCATGCTGTTTCATTCGCTTCTGGA
TTCCGGATCAAACGCATATGTCGAGCAGATTTCGTTTACAGTCAGCGGGGATTTATGCATTGATACATTCCAAAAAAGTC
TGGATATGCTTGTCAGCCGCTATGATATTTTCAGAACGATTTTCATAAAAGAAGTGCCTGACCTTGAAGGTCCGCAGCAG
GTTGTCCTTTCACGCCGTGACACAGCCGTACAGACTGAGAACATTTCAGATTATTCGGAAGAACGGCAGCAAAGCATCAT
TGAGGAATTCAAGGAAACCGACCGGCATAAGGGGTTTGATCTGCAAAAAGGCCCCTTAATGCGCCTGGCTCTTTTTCAAA
CGGGAGAAAACCGCCATACATGCGTTTGGACTCATCATCACATTATGATGGACGGCTGGAGCTTGGGCATTGTGCTGAAA
GATTTCTTCAGCATGTATTATGCGATCCGAAACGGGCGGCCTGTAAACCTCGGCAGTCCGGCTCCTTACAGTTCTTATAT
CAAATGGCTCCGAAGCCGGAATAAAGAAGAAACGTCAGCGTTCTGGTCGCGCTGCTTGGAAGATTACGGAGAAGTCGTTT
CCGTTCCGCAAACGAAGAATAAGCCGGCGCAAAACGGTTATGCATCTGAGCATTTTCAATTTTCCCTTGAGTCTGAAACC
GTGCAAAAACTGACAGACATTGCCCGAAGCACCGGGGTCACGCTGAATACTTTATTTACGAGCATTTGGGGACTGCTTCT
CCACCGTTACAACGGCACTGAAGATGCGGTATTCGGTTCAGTTGTTTCCGGCAGGCCGTCAGCTATCGCCGGCATCGAAT
CAATGGCCGGACTGTTTATCAATACCGTGCCGGTAAGGGTGCGCGCGGCGGGGGATATGACTTTTTCTTCTCTTCTCAAA
AAGGTGCAAAAAGAGTCACTCGCTGCAGAAGAGCACAGCTATTATCCGCTTTATGACATCCAAAACGAGAGCGGCCTGCA
AAAAGATCTCTTGAACCACATCCTGGTTTTTGAGAATTATCCGGTTCAGATGCAGACTGCGGTAAACGGCTGGAAGCAAA
CCGAAAGCAGTGCGCTCTCACTTGAAAACTTTTCGATGGCGGAAGAAACCAATTACGATCTTAACGTCGTCATCGTTCCG
GGAGAAGAGTTTTATGTGAAATTCAGCTACAATGCGGGCATCTACGATCGGGAAGACATGAAACGGATCAAAGGGCATAT
TCTGGAGGTCATCTCCTGTGTAACGGAAGATCCGGACAGGCTTTTATCAAGCATCAGTCTCGTGCCTCCAGAGGAAGAAG
CCTTGATTCATTCGTTTAACGAAACGAACCGTCCGTACCCTGAGACAACCGTTCATGGGCTGTTTGAAGAACAGGCGGCA
AAAACGCCTGACCAAGAGGCGTTGAGATATAACGGGGTAAGCTGGAGCTACAAGAAATTAAATCAGCGGGCGAATCAGAT
TGCGCATGCGTTAAGGGAAAAAGGCGCACGCCCCGACCAGATCACCGCTGTTATGCTGCGCCGATCAATGAGTACGGTTG
CCGCTCTGCTCGGAATTTGGAAGTCGGGCAGCGCCTATATGCCGATTGATGCGGAATTTCCGCCTGAACGGATTTCATTT
TTACTGAGAGACAGTGAAGCCTCACTGCTCGTGACCGAAAAGGACCTGCTCCCCCTCATTCCGCCGCATTTCAAGGGCAG
CGTCGTCATCATGGAGGAAACGGTTTCCCAGCAGACTGCACCGCTTCCGCCGGTATCTGACAGCGGAAATTGGGCGTATG
TCATTTACACCTCCGGAACGACAGGCCGGCCGAAAGGGGTGCTTGTACAACACAAAGCGATCAGCAATACATTGCAATGG
CGGCGTGAAGAATACGGGATGACAGAAGGGGACATAGCGCTTCATCTTTTTTCATACGTATTTGACGGGTCATTAACGAG
TCTTTTCACTCCGCTTCTGTCGGGCGCCTGTGTATTGTTAACTGATGAAGATGATGCGAAAGACGTCCTTTCAATAAAAC
AGAAAATCACCCGCCACGGAGTGAGCCATCTTCTGATCGTTCCGTCTCTGTATCGCGTTCTGCTTGATTCGCTGACGAAA
AAGGATGCGCAGACGCTTCGGGCGGTGACATTTGCCGGGGAAGCGGCCACTCCTGATATCGTGGAAGCGAGCCGCGGCAT
ATGCCCGAATGCCGAGCTGCTGAATGAATACGGGCCGACGGAAAACAGTGTGGCCACGACGATTCTGCGCAACCTGCAAA
AAAGCAGCCGGATTACGATCGGGCGCCCGATTGCCAACACTTCTGTCTATATTATGCATGGAGATCGGCTGCAGCCGGTC
GGAGCCGTCGGTGAACTGTGTATTTCCGGAAAAGGTCTGGCGGACGGATATTTTCAGCAAAAAGAGCTGACGGACAAAGT
CTTTACCCCTCATCCGTTTCGTGAAGGTGAACGGCTGTACAGAACGGGAGATGCAGCCCGATTTTTACCGGACGGAACGA
TTGAATATATGGGACGCTTTGACGATCAGGTGAAGGTAAGAGGTTACAGAATTGAATTAGGAGAAATCGAAACGGCACTC
AGAAGTCTGTCCGGGGTAAAAGAGGCGGCAGTCACCGTGCGCAAAATGGCGGACGGGGAACAGGAGCTTGCAGCTTATGT
CGTACTGGAAAATGCGGGTGTGACATTTAAACCGCACGCTGAATTGGCCGGGAGATTACCTGCTTATATGATACCGGGAA
GCTTTACCAAATTAACGGAAATGCCGCTGTCTGTGAGCGGAAAACTTGATCGGGCCGCACTTCCTGAGCCGAAAGAAGCC
GAGAGAACCGGTGATTATCAAGCTCCGCGCACAATGCTTGAGACTGAGCTGCTGTCTATTTGGCAAGAAGTGCTGAAACG
GGAACACATCAGTATGAGAGATGATTTCTTCCAAATCGGCGGACAGTCGCTGAAAGCCGCGTCGCTTGTTTCAAACATAC
ATAAACGGCTGCAAATTGAACTTGCCGTCCGCCATGTTTTTGAACATCCGACCATCGAGAGCATGGCCCGCTTCCTTGAA
CAGAGGAAAAGAGGAGAATATGCAGAAATCACGCCTGCTGTGGCAAAGGACTTGTACCCGCTATCTTTTGCGCAAAAAAG
GCTCTATGCCCTTCATCAGCTGGCAGCGGACAGTACGGGCTATCATATGCCCGCTTGTCTGGAACTGAGCGGCAGACTCA
ACCGGGATCGTCTGCACGAAGCCTTTTCAGCGCTGTTACAAAGGCATGAAGCGTTACGCACATCATTTGTTTTACGAAAC
GGGGAGCCGATGCAGCACATACATGCACATGTCGATCTTGACCTCACAGAGATTCACATGCCATCCGGGAACCTTCTTCA
AGAGGTGATGGAAACTTTCGTCAAACCGTTTGACGTGGAAAAAGCGCCGCTTTTGAGAGTGACTTTAGCCAAAGTTACTG
AAGAACGTCATTTTCTGCTGCTTGATATGCATCATCTTATCGCAGACGGTGTGTCAATGAGCGTTCTGATTCAAGAATTG
ACGGATTTGTACAGAGGAAAAGAGTTGCGGCCGTTAAAACTCCAGTACAAAGATTTTTCCGTCTGGCAGCATGAGCGGTT
TGCCGCTGAAGAATTCAAAAGACATGAGCGTTATTGGCTGGAGACGATCGGGGAAAACATTCCCGTACTTGATCTGCCGC
TCGATAAAAAGCGCCCGCCGCTTCCTGATTTCAGCGGGTCCGTTGTTCGAACGCGCCTTCAAAAGGAAACGGCGGAGAAC
TTGCGCCAACTCATGGATGAGACGGGTTCGACACTGTATATGATTCTTTTGGCAAGCTACTCCTTGTTCCTTTCTAAATT
GAGCGGGCAGGAAGACATTGTCGTCGGTTCACCTGCGGCCGGCAGAAGCCGCGCTGAGCTTGACGGGGTCATCGGCATGT
TTGTAAATACCGTGGCAATGAGAAGCAGGCCGAAAGGGGATAAGACATTCCGCGCTTATTTAGAAGAGGTGAAAATGCTC
GCCCTCGGCGCGGCCGAACATCAGGACTTCCCGTTTGAAGAACTTGCCCAAAAGCTTGATACACACCGGGAAGTCAATCG
CAATCCGCTGTTTGATGCCATGCTCGTTTTGCAAAACAGTGATGATTTCGAAGTGAACCTTCCGGGCTTATCCGTTTCTT
CACATGCAGTGAAGCATGACATTTCAAAATTCGACTTGACGCTTCATGCCGAGGAACGGCCGGATGGCTCACTGGATTTT
CATTTTGAATACAGTACCGCGTTGTTTGAAAAAGATACGATCGAACGGTGGGCCGGTCATTTTAAAGAGCTTTTAGGACA
AATCGCATCGGATTACGAACGGAAGCTGTCTGACATTCATTTGCTGGGCATAAACGAGCGGCAGATGCTTCTTCAAGCGG
AAAATCAAACGGCGGAGTATCCGAGGCATGAAACGATTGTCAGTTTATTCGAAGCACAGGCGGAAAAAATGCCGAATCAA
ATTGCAGCCGTCATGTCTCATGAGCGTCTCACCTACCGCGAGCTCAATGAAAAGGCGGATCGAATCGCCGATATGCTGTC
GGAAAACGGCATCCGCTCCGGACAGATTGTCGGAATTATGACCGAACGATCTCCGGATATGCTGATTGGGATTCTCGGTA
TTTTAAAAGCGGGAGGAGCTTATCTGCCGATTGATCCTGACTATCCGGACGAGCGGATTTCATTTATGCTGACTGACAGC
GGCGCGCGTGCTCTGTTGACGCAATCGGGTCTTGGGATATCCGGAATGGATGGGCTGCCGGTTTTATACATCGATAAGCC
TGAATCCGTTTCAGCAGACAGAACGAAAGAAATGATAACGCCTGAACAGCCGGCTTACGTGATTTACACATCGGGCACAA
CCGGAAAACCGAAAGGCGTTATGACGGAACACCGCAATGTCATCAGCCTTATCACACATAAAGGACTGCCGTTTGATTTC
GGCTCTGAAGACGTCTGGACGCTGTTCCACTCCTATTGCTTTGATTTTTCTGTATGGGAAATATTCGGCGCGCTCTTATA
CGGCGGAAAGGTGGTTATCGTGCCGAAAGACACAGCCCGTGATCCGCATTTGTACCGGCAGCTGCTGCAAAGTGAAGGCG
TAACGGTGCTGAACCAAACGCCGACGGCTTTTTCCGGACTCATTCATGAAGAGGCCGGGCATACGGACAAGCTGAAGCTT
CGATATGTCATTTTCGGCGGAGAAGCGCTTCAGCCAGGCATGCTGAAAAGCTGGAAAGAAAAGTACCCGGAGACGGAGCT
TGTTAATATGTACGGTATTACGGAAACCACGGTTCACGTCACATGCAAAAAACTGAATATGGATGATATTGAGAGAAACA
AAAGCAATATCGGCAGACCGCTGGAAACCCTTCATGCTTTTGTTATGGACGCCTATATGAATCCGCAGCCGATCGGAATT
CCCGGTGAGCTTTATATCGGCGGGGAAGGCGTCGCGAGGGGATATGTAAACAGGGATGATTTAACCGCCTCCCGTTTCAT
CACGAATCCGCACGTTTCCGGCATGCGGCTCTACCGGACGGGTGATATCGCCAAAAGGCTCTTAAATGGCGAACTGGAAT
ATGTCGGGCGGAAAGATGCGCAAGTAAAAGTCAGAGGCCACAGAATTGAGCTGGGAGAAATTAAATCAGCGCTGCAAGAG
CTTTCCTCCGTGAAAGAGGCCGCCGTGATCACACGTGCTGATCAGCACGGTCAGCACTCCATTTACGCATACGCGGTCTT
ACACGGGAACGAAAAGATAAAAGAAGCAGAGATTCAGGCCTCTCTCAGAGCTTTTCTGCCGGAATATATGATTCCCGCCC
GCTTGATAGCGCTTGATGAACTGCCTTTGACGGCGAATGGGAAGCTGGACGAGAAGGCGCTCCCGCAGCCTGAATTAAAT
GATAGCCTTGGAGATGATATCAGCCTGAGAAATGAAACTGAAGAAATGATGGCTGACATTTGGGAAGAACTCTTAGGTGT
TGAAGGCCTCGGCCCCAATGCTCATTTCTTCCATCTCGGCGGGGATTCGATTAAAGCGCTGCAAGTATGTGCGAGGCTGA
AACAGCAGGGCTATGAAACGACCGTCCGCGAGCTGTTCGAGCATCAGACACTGGGAGAAGTATCGATGCGGCTCCGGAAA
GTCCGCCGCGTGATTGATCAGGCTCCCGTCACGGGAGACGTGCCGCTGACGCCGATCCAGCACTGGTTCTTGTCGCAATC
ATTGCCGCATGATCATTTTAATCAGTCCGTAATGCTCCGCAGTGCGGACAGAATCAATGAATCTGCTATGAGAAAAGCGC
TGGCACAGCTCGCGGTTCATCATGACGCATTACGGATCGTATGCGGCACGCAAAACGGATCGGTGACTCAATACAACAGA
GCGGAAAACCTTTCTGAAGAAGAACTCTTTACGTTTGAAACGCATGACGTGAGAGGGAAAGGGTCATTACAAGAGGAGCA
CGTCGCAATTGAACAGGCGGCCGCCCGTATTCAAACTTCCATTCGGCTGGAGACGGGGCCGCTCGTAGCTGTCGGATTAT
TTCACGCTAATGATGGCGATCATCTGCTGCTTTCCATTCATCACCTTGTCATTGACGGTGTATCATGGCGGATTTTATTT
GAAGATCTCACCGCGTGCTACAGGCAGGCGCTCGAAGGAAAAGAAACCGCGCTTCCGGCAAAAACCGATTCCTATCAGAC
TTACGCGAAGCAAATCTCTGATTATGCAAAAAGCCGCCGGCTGTTACAGGAAGCAGACTACTGGTCCGAAAGAGAAAAAA
TGGCGGTCGAACCGCTTCCGAAAGATGCCCGCATCTCTTCCAATCTTCTGAAAGATACAGATGTGATGACCGTTAAATTG
ACAAAACAGGAGACTGAGCAGCTGTTAACGGAAGCGAACAGAGCATACACAACAGAGACGGGTGAATTATTGCTTGCCGC
GTTAAGCCTTGCGCTGAACAGATGGACCGGAAACGAGACATTCAAAATCAGCATGGAAGGCCACGGAAGGGAAGAGCACT
TGGAGCATCTTGATATCAGCAGAACCATCGGTTGGTTTACGTCAATTTATCCGGTATTGGTTGACGCAAGTTTTCAAGAT
CAGGCTGATGACGGCGAGCGGCTTGGCTATCACATTAAGCGGACAAAAGACATGATGCGCCGCATTCCGCATAAAGGAGC
GGGATACGGAGTGCTGAAATATATAAGCAAACTCTGGGAAGAGACGGAATCCGATTCTCCTGAAATCAGTTTTAACTATC
TGGGACAGTTTGACCGTGAAATCCGTTCCAGCGGCTTTGGTGTTTCTCCCGTAAAAGCGGGAAATGAAGTCAGCCCAGAC
TGGGAACGTCCGTACACACTTGATATCAGCGGCTCCGTATCGTCGGAATGTCTCAGCATGCATGTCGTGTACAACCGTTT
TCAGTATCAAAAAGAAACGATTGAAGTTTTGACGGGATATTTTCATGCCTTTCTCAAGCAGATCATCTCGCATTGCACAG
GCAAAGAGGAGCGTGAATGGAGCGCCGCTGATTTCAGTGACGAGGAGTTAACGCTGGAAGATCTGAGTGACATTATGGGA
GCCGTCAACAAACTATAG

Upstream 100 bases:

>100_bases
TTAACGGATTACAGCCATACAGAATTGACCGCTCAAGCACTATCAAGTATTGAAGATCTCGTAAAAGGACTTTAATTTCA
TAAAAAGGTGTGTGGCATTC

Downstream 100 bases:

>100_bases
AAAAGGAGTGGCGCAATGGGGCAGCAACCGGAAATACAAGATATATATCCTTTATCTTTTATGCAGGAGGGCATGCTTTT
TCATTCTCTGTTGGATCATG

Product: FenB

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Peptide synthase 2; ATP-dependent tyrosine adenylase 1; TyrA 1; Tyrosine activase 1; ATP-dependent threonine adenylase; ThrA; Threonine activase [H]

Number of amino acids: Translated: 2565; Mature: 2564

Protein sequence:

>2565_residues
MTQATEIQDIYPLSYMQEGMLFHSLLDSGSNAYVEQISFTVSGDLCIDTFQKSLDMLVSRYDIFRTIFIKEVPDLEGPQQ
VVLSRRDTAVQTENISDYSEERQQSIIEEFKETDRHKGFDLQKGPLMRLALFQTGENRHTCVWTHHHIMMDGWSLGIVLK
DFFSMYYAIRNGRPVNLGSPAPYSSYIKWLRSRNKEETSAFWSRCLEDYGEVVSVPQTKNKPAQNGYASEHFQFSLESET
VQKLTDIARSTGVTLNTLFTSIWGLLLHRYNGTEDAVFGSVVSGRPSAIAGIESMAGLFINTVPVRVRAAGDMTFSSLLK
KVQKESLAAEEHSYYPLYDIQNESGLQKDLLNHILVFENYPVQMQTAVNGWKQTESSALSLENFSMAEETNYDLNVVIVP
GEEFYVKFSYNAGIYDREDMKRIKGHILEVISCVTEDPDRLLSSISLVPPEEEALIHSFNETNRPYPETTVHGLFEEQAA
KTPDQEALRYNGVSWSYKKLNQRANQIAHALREKGARPDQITAVMLRRSMSTVAALLGIWKSGSAYMPIDAEFPPERISF
LLRDSEASLLVTEKDLLPLIPPHFKGSVVIMEETVSQQTAPLPPVSDSGNWAYVIYTSGTTGRPKGVLVQHKAISNTLQW
RREEYGMTEGDIALHLFSYVFDGSLTSLFTPLLSGACVLLTDEDDAKDVLSIKQKITRHGVSHLLIVPSLYRVLLDSLTK
KDAQTLRAVTFAGEAATPDIVEASRGICPNAELLNEYGPTENSVATTILRNLQKSSRITIGRPIANTSVYIMHGDRLQPV
GAVGELCISGKGLADGYFQQKELTDKVFTPHPFREGERLYRTGDAARFLPDGTIEYMGRFDDQVKVRGYRIELGEIETAL
RSLSGVKEAAVTVRKMADGEQELAAYVVLENAGVTFKPHAELAGRLPAYMIPGSFTKLTEMPLSVSGKLDRAALPEPKEA
ERTGDYQAPRTMLETELLSIWQEVLKREHISMRDDFFQIGGQSLKAASLVSNIHKRLQIELAVRHVFEHPTIESMARFLE
QRKRGEYAEITPAVAKDLYPLSFAQKRLYALHQLAADSTGYHMPACLELSGRLNRDRLHEAFSALLQRHEALRTSFVLRN
GEPMQHIHAHVDLDLTEIHMPSGNLLQEVMETFVKPFDVEKAPLLRVTLAKVTEERHFLLLDMHHLIADGVSMSVLIQEL
TDLYRGKELRPLKLQYKDFSVWQHERFAAEEFKRHERYWLETIGENIPVLDLPLDKKRPPLPDFSGSVVRTRLQKETAEN
LRQLMDETGSTLYMILLASYSLFLSKLSGQEDIVVGSPAAGRSRAELDGVIGMFVNTVAMRSRPKGDKTFRAYLEEVKML
ALGAAEHQDFPFEELAQKLDTHREVNRNPLFDAMLVLQNSDDFEVNLPGLSVSSHAVKHDISKFDLTLHAEERPDGSLDF
HFEYSTALFEKDTIERWAGHFKELLGQIASDYERKLSDIHLLGINERQMLLQAENQTAEYPRHETIVSLFEAQAEKMPNQ
IAAVMSHERLTYRELNEKADRIADMLSENGIRSGQIVGIMTERSPDMLIGILGILKAGGAYLPIDPDYPDERISFMLTDS
GARALLTQSGLGISGMDGLPVLYIDKPESVSADRTKEMITPEQPAYVIYTSGTTGKPKGVMTEHRNVISLITHKGLPFDF
GSEDVWTLFHSYCFDFSVWEIFGALLYGGKVVIVPKDTARDPHLYRQLLQSEGVTVLNQTPTAFSGLIHEEAGHTDKLKL
RYVIFGGEALQPGMLKSWKEKYPETELVNMYGITETTVHVTCKKLNMDDIERNKSNIGRPLETLHAFVMDAYMNPQPIGI
PGELYIGGEGVARGYVNRDDLTASRFITNPHVSGMRLYRTGDIAKRLLNGELEYVGRKDAQVKVRGHRIELGEIKSALQE
LSSVKEAAVITRADQHGQHSIYAYAVLHGNEKIKEAEIQASLRAFLPEYMIPARLIALDELPLTANGKLDEKALPQPELN
DSLGDDISLRNETEEMMADIWEELLGVEGLGPNAHFFHLGGDSIKALQVCARLKQQGYETTVRELFEHQTLGEVSMRLRK
VRRVIDQAPVTGDVPLTPIQHWFLSQSLPHDHFNQSVMLRSADRINESAMRKALAQLAVHHDALRIVCGTQNGSVTQYNR
AENLSEEELFTFETHDVRGKGSLQEEHVAIEQAAARIQTSIRLETGPLVAVGLFHANDGDHLLLSIHHLVIDGVSWRILF
EDLTACYRQALEGKETALPAKTDSYQTYAKQISDYAKSRRLLQEADYWSEREKMAVEPLPKDARISSNLLKDTDVMTVKL
TKQETEQLLTEANRAYTTETGELLLAALSLALNRWTGNETFKISMEGHGREEHLEHLDISRTIGWFTSIYPVLVDASFQD
QADDGERLGYHIKRTKDMMRRIPHKGAGYGVLKYISKLWEETESDSPEISFNYLGQFDREIRSSGFGVSPVKAGNEVSPD
WERPYTLDISGSVSSECLSMHVVYNRFQYQKETIEVLTGYFHAFLKQIISHCTGKEEREWSAADFSDEELTLEDLSDIMG
AVNKL

Sequences:

>Translated_2565_residues
MTQATEIQDIYPLSYMQEGMLFHSLLDSGSNAYVEQISFTVSGDLCIDTFQKSLDMLVSRYDIFRTIFIKEVPDLEGPQQ
VVLSRRDTAVQTENISDYSEERQQSIIEEFKETDRHKGFDLQKGPLMRLALFQTGENRHTCVWTHHHIMMDGWSLGIVLK
DFFSMYYAIRNGRPVNLGSPAPYSSYIKWLRSRNKEETSAFWSRCLEDYGEVVSVPQTKNKPAQNGYASEHFQFSLESET
VQKLTDIARSTGVTLNTLFTSIWGLLLHRYNGTEDAVFGSVVSGRPSAIAGIESMAGLFINTVPVRVRAAGDMTFSSLLK
KVQKESLAAEEHSYYPLYDIQNESGLQKDLLNHILVFENYPVQMQTAVNGWKQTESSALSLENFSMAEETNYDLNVVIVP
GEEFYVKFSYNAGIYDREDMKRIKGHILEVISCVTEDPDRLLSSISLVPPEEEALIHSFNETNRPYPETTVHGLFEEQAA
KTPDQEALRYNGVSWSYKKLNQRANQIAHALREKGARPDQITAVMLRRSMSTVAALLGIWKSGSAYMPIDAEFPPERISF
LLRDSEASLLVTEKDLLPLIPPHFKGSVVIMEETVSQQTAPLPPVSDSGNWAYVIYTSGTTGRPKGVLVQHKAISNTLQW
RREEYGMTEGDIALHLFSYVFDGSLTSLFTPLLSGACVLLTDEDDAKDVLSIKQKITRHGVSHLLIVPSLYRVLLDSLTK
KDAQTLRAVTFAGEAATPDIVEASRGICPNAELLNEYGPTENSVATTILRNLQKSSRITIGRPIANTSVYIMHGDRLQPV
GAVGELCISGKGLADGYFQQKELTDKVFTPHPFREGERLYRTGDAARFLPDGTIEYMGRFDDQVKVRGYRIELGEIETAL
RSLSGVKEAAVTVRKMADGEQELAAYVVLENAGVTFKPHAELAGRLPAYMIPGSFTKLTEMPLSVSGKLDRAALPEPKEA
ERTGDYQAPRTMLETELLSIWQEVLKREHISMRDDFFQIGGQSLKAASLVSNIHKRLQIELAVRHVFEHPTIESMARFLE
QRKRGEYAEITPAVAKDLYPLSFAQKRLYALHQLAADSTGYHMPACLELSGRLNRDRLHEAFSALLQRHEALRTSFVLRN
GEPMQHIHAHVDLDLTEIHMPSGNLLQEVMETFVKPFDVEKAPLLRVTLAKVTEERHFLLLDMHHLIADGVSMSVLIQEL
TDLYRGKELRPLKLQYKDFSVWQHERFAAEEFKRHERYWLETIGENIPVLDLPLDKKRPPLPDFSGSVVRTRLQKETAEN
LRQLMDETGSTLYMILLASYSLFLSKLSGQEDIVVGSPAAGRSRAELDGVIGMFVNTVAMRSRPKGDKTFRAYLEEVKML
ALGAAEHQDFPFEELAQKLDTHREVNRNPLFDAMLVLQNSDDFEVNLPGLSVSSHAVKHDISKFDLTLHAEERPDGSLDF
HFEYSTALFEKDTIERWAGHFKELLGQIASDYERKLSDIHLLGINERQMLLQAENQTAEYPRHETIVSLFEAQAEKMPNQ
IAAVMSHERLTYRELNEKADRIADMLSENGIRSGQIVGIMTERSPDMLIGILGILKAGGAYLPIDPDYPDERISFMLTDS
GARALLTQSGLGISGMDGLPVLYIDKPESVSADRTKEMITPEQPAYVIYTSGTTGKPKGVMTEHRNVISLITHKGLPFDF
GSEDVWTLFHSYCFDFSVWEIFGALLYGGKVVIVPKDTARDPHLYRQLLQSEGVTVLNQTPTAFSGLIHEEAGHTDKLKL
RYVIFGGEALQPGMLKSWKEKYPETELVNMYGITETTVHVTCKKLNMDDIERNKSNIGRPLETLHAFVMDAYMNPQPIGI
PGELYIGGEGVARGYVNRDDLTASRFITNPHVSGMRLYRTGDIAKRLLNGELEYVGRKDAQVKVRGHRIELGEIKSALQE
LSSVKEAAVITRADQHGQHSIYAYAVLHGNEKIKEAEIQASLRAFLPEYMIPARLIALDELPLTANGKLDEKALPQPELN
DSLGDDISLRNETEEMMADIWEELLGVEGLGPNAHFFHLGGDSIKALQVCARLKQQGYETTVRELFEHQTLGEVSMRLRK
VRRVIDQAPVTGDVPLTPIQHWFLSQSLPHDHFNQSVMLRSADRINESAMRKALAQLAVHHDALRIVCGTQNGSVTQYNR
AENLSEEELFTFETHDVRGKGSLQEEHVAIEQAAARIQTSIRLETGPLVAVGLFHANDGDHLLLSIHHLVIDGVSWRILF
EDLTACYRQALEGKETALPAKTDSYQTYAKQISDYAKSRRLLQEADYWSEREKMAVEPLPKDARISSNLLKDTDVMTVKL
TKQETEQLLTEANRAYTTETGELLLAALSLALNRWTGNETFKISMEGHGREEHLEHLDISRTIGWFTSIYPVLVDASFQD
QADDGERLGYHIKRTKDMMRRIPHKGAGYGVLKYISKLWEETESDSPEISFNYLGQFDREIRSSGFGVSPVKAGNEVSPD
WERPYTLDISGSVSSECLSMHVVYNRFQYQKETIEVLTGYFHAFLKQIISHCTGKEEREWSAADFSDEELTLEDLSDIMG
AVNKL
>Mature_2564_residues
TQATEIQDIYPLSYMQEGMLFHSLLDSGSNAYVEQISFTVSGDLCIDTFQKSLDMLVSRYDIFRTIFIKEVPDLEGPQQV
VLSRRDTAVQTENISDYSEERQQSIIEEFKETDRHKGFDLQKGPLMRLALFQTGENRHTCVWTHHHIMMDGWSLGIVLKD
FFSMYYAIRNGRPVNLGSPAPYSSYIKWLRSRNKEETSAFWSRCLEDYGEVVSVPQTKNKPAQNGYASEHFQFSLESETV
QKLTDIARSTGVTLNTLFTSIWGLLLHRYNGTEDAVFGSVVSGRPSAIAGIESMAGLFINTVPVRVRAAGDMTFSSLLKK
VQKESLAAEEHSYYPLYDIQNESGLQKDLLNHILVFENYPVQMQTAVNGWKQTESSALSLENFSMAEETNYDLNVVIVPG
EEFYVKFSYNAGIYDREDMKRIKGHILEVISCVTEDPDRLLSSISLVPPEEEALIHSFNETNRPYPETTVHGLFEEQAAK
TPDQEALRYNGVSWSYKKLNQRANQIAHALREKGARPDQITAVMLRRSMSTVAALLGIWKSGSAYMPIDAEFPPERISFL
LRDSEASLLVTEKDLLPLIPPHFKGSVVIMEETVSQQTAPLPPVSDSGNWAYVIYTSGTTGRPKGVLVQHKAISNTLQWR
REEYGMTEGDIALHLFSYVFDGSLTSLFTPLLSGACVLLTDEDDAKDVLSIKQKITRHGVSHLLIVPSLYRVLLDSLTKK
DAQTLRAVTFAGEAATPDIVEASRGICPNAELLNEYGPTENSVATTILRNLQKSSRITIGRPIANTSVYIMHGDRLQPVG
AVGELCISGKGLADGYFQQKELTDKVFTPHPFREGERLYRTGDAARFLPDGTIEYMGRFDDQVKVRGYRIELGEIETALR
SLSGVKEAAVTVRKMADGEQELAAYVVLENAGVTFKPHAELAGRLPAYMIPGSFTKLTEMPLSVSGKLDRAALPEPKEAE
RTGDYQAPRTMLETELLSIWQEVLKREHISMRDDFFQIGGQSLKAASLVSNIHKRLQIELAVRHVFEHPTIESMARFLEQ
RKRGEYAEITPAVAKDLYPLSFAQKRLYALHQLAADSTGYHMPACLELSGRLNRDRLHEAFSALLQRHEALRTSFVLRNG
EPMQHIHAHVDLDLTEIHMPSGNLLQEVMETFVKPFDVEKAPLLRVTLAKVTEERHFLLLDMHHLIADGVSMSVLIQELT
DLYRGKELRPLKLQYKDFSVWQHERFAAEEFKRHERYWLETIGENIPVLDLPLDKKRPPLPDFSGSVVRTRLQKETAENL
RQLMDETGSTLYMILLASYSLFLSKLSGQEDIVVGSPAAGRSRAELDGVIGMFVNTVAMRSRPKGDKTFRAYLEEVKMLA
LGAAEHQDFPFEELAQKLDTHREVNRNPLFDAMLVLQNSDDFEVNLPGLSVSSHAVKHDISKFDLTLHAEERPDGSLDFH
FEYSTALFEKDTIERWAGHFKELLGQIASDYERKLSDIHLLGINERQMLLQAENQTAEYPRHETIVSLFEAQAEKMPNQI
AAVMSHERLTYRELNEKADRIADMLSENGIRSGQIVGIMTERSPDMLIGILGILKAGGAYLPIDPDYPDERISFMLTDSG
ARALLTQSGLGISGMDGLPVLYIDKPESVSADRTKEMITPEQPAYVIYTSGTTGKPKGVMTEHRNVISLITHKGLPFDFG
SEDVWTLFHSYCFDFSVWEIFGALLYGGKVVIVPKDTARDPHLYRQLLQSEGVTVLNQTPTAFSGLIHEEAGHTDKLKLR
YVIFGGEALQPGMLKSWKEKYPETELVNMYGITETTVHVTCKKLNMDDIERNKSNIGRPLETLHAFVMDAYMNPQPIGIP
GELYIGGEGVARGYVNRDDLTASRFITNPHVSGMRLYRTGDIAKRLLNGELEYVGRKDAQVKVRGHRIELGEIKSALQEL
SSVKEAAVITRADQHGQHSIYAYAVLHGNEKIKEAEIQASLRAFLPEYMIPARLIALDELPLTANGKLDEKALPQPELND
SLGDDISLRNETEEMMADIWEELLGVEGLGPNAHFFHLGGDSIKALQVCARLKQQGYETTVRELFEHQTLGEVSMRLRKV
RRVIDQAPVTGDVPLTPIQHWFLSQSLPHDHFNQSVMLRSADRINESAMRKALAQLAVHHDALRIVCGTQNGSVTQYNRA
ENLSEEELFTFETHDVRGKGSLQEEHVAIEQAAARIQTSIRLETGPLVAVGLFHANDGDHLLLSIHHLVIDGVSWRILFE
DLTACYRQALEGKETALPAKTDSYQTYAKQISDYAKSRRLLQEADYWSEREKMAVEPLPKDARISSNLLKDTDVMTVKLT
KQETEQLLTEANRAYTTETGELLLAALSLALNRWTGNETFKISMEGHGREEHLEHLDISRTIGWFTSIYPVLVDASFQDQ
ADDGERLGYHIKRTKDMMRRIPHKGAGYGVLKYISKLWEETESDSPEISFNYLGQFDREIRSSGFGVSPVKAGNEVSPDW
ERPYTLDISGSVSSECLSMHVVYNRFQYQKETIEVLTGYFHAFLKQIISHCTGKEEREWSAADFSDEELTLEDLSDIMGA
VNKL

Specific function: This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Tyr and Thr as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Thr residue is further converted to the D-allo-isomer form. The activation sit

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=595, Percent_Identity=26.890756302521, Blast_Score=150, Evalue=1e-35,
Organism=Homo sapiens, GI187761345, Length=560, Percent_Identity=23.2142857142857, Blast_Score=117, Evalue=1e-25,
Organism=Homo sapiens, GI187761343, Length=560, Percent_Identity=23.2142857142857, Blast_Score=117, Evalue=1e-25,
Organism=Homo sapiens, GI38505220, Length=529, Percent_Identity=25.5198487712665, Blast_Score=115, Evalue=4e-25,
Organism=Homo sapiens, GI156151445, Length=553, Percent_Identity=24.0506329113924, Blast_Score=110, Evalue=2e-23,
Organism=Homo sapiens, GI42544132, Length=505, Percent_Identity=22.970297029703, Blast_Score=103, Evalue=2e-21,
Organism=Homo sapiens, GI122937307, Length=507, Percent_Identity=22.879684418146, Blast_Score=102, Evalue=4e-21,
Organism=Homo sapiens, GI157311624, Length=512, Percent_Identity=24.609375, Blast_Score=99, Evalue=6e-20,
Organism=Homo sapiens, GI157311622, Length=512, Percent_Identity=24.609375, Blast_Score=99, Evalue=6e-20,
Organism=Homo sapiens, GI58082049, Length=504, Percent_Identity=24.8015873015873, Blast_Score=95, Evalue=1e-18,
Organism=Homo sapiens, GI28416953, Length=590, Percent_Identity=23.3898305084746, Blast_Score=87, Evalue=3e-16,
Organism=Homo sapiens, GI13375727, Length=554, Percent_Identity=21.6606498194946, Blast_Score=80, Evalue=3e-14,
Organism=Escherichia coli, GI1786801, Length=1066, Percent_Identity=28.4240150093809, Blast_Score=365, Evalue=1e-101,
Organism=Escherichia coli, GI1788107, Length=548, Percent_Identity=26.2773722627737, Blast_Score=125, Evalue=3e-29,
Organism=Escherichia coli, GI1790505, Length=548, Percent_Identity=26.0948905109489, Blast_Score=122, Evalue=3e-28,
Organism=Escherichia coli, GI145693145, Length=556, Percent_Identity=24.1007194244604, Blast_Score=109, Evalue=3e-24,
Organism=Escherichia coli, GI221142682, Length=499, Percent_Identity=22.2444889779559, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1789201, Length=362, Percent_Identity=27.0718232044199, Blast_Score=94, Evalue=9e-20,
Organism=Escherichia coli, GI1786810, Length=511, Percent_Identity=26.4187866927593, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17550940, Length=1171, Percent_Identity=23.398804440649, Blast_Score=209, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17556356, Length=576, Percent_Identity=26.3888888888889, Blast_Score=155, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17560308, Length=549, Percent_Identity=24.0437158469945, Blast_Score=124, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17558820, Length=480, Percent_Identity=25.625, Blast_Score=113, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994694, Length=545, Percent_Identity=23.1192660550459, Blast_Score=112, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994690, Length=545, Percent_Identity=23.4862385321101, Blast_Score=111, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71994703, Length=547, Percent_Identity=23.400365630713, Blast_Score=111, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17531443, Length=473, Percent_Identity=23.0443974630021, Blast_Score=105, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI32564422, Length=711, Percent_Identity=23.4880450070323, Blast_Score=97, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560140, Length=483, Percent_Identity=22.5672877846791, Blast_Score=97, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32564420, Length=711, Percent_Identity=23.4880450070323, Blast_Score=97, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32563687, Length=424, Percent_Identity=24.0566037735849, Blast_Score=95, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17557194, Length=505, Percent_Identity=23.960396039604, Blast_Score=94, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17538037, Length=521, Percent_Identity=24.3761996161228, Blast_Score=94, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559526, Length=362, Percent_Identity=22.9281767955801, Blast_Score=70, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71985884, Length=388, Percent_Identity=24.4845360824742, Blast_Score=69, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=960, Percent_Identity=23.3333333333333, Blast_Score=214, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6323182, Length=554, Percent_Identity=23.2851985559567, Blast_Score=86, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6319699, Length=358, Percent_Identity=24.8603351955307, Blast_Score=82, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319264, Length=507, Percent_Identity=24.0631163708087, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24648676, Length=626, Percent_Identity=30.1916932907348, Blast_Score=237, Evalue=9e-62,
Organism=Drosophila melanogaster, GI24581924, Length=543, Percent_Identity=23.9410681399632, Blast_Score=116, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24582852, Length=602, Percent_Identity=23.7541528239203, Blast_Score=100, Evalue=2e-20,
Organism=Drosophila melanogaster, GI18859661, Length=511, Percent_Identity=24.0704500978474, Blast_Score=96, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21355181, Length=493, Percent_Identity=22.1095334685598, Blast_Score=74, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356441, Length=443, Percent_Identity=23.0248306997743, Blast_Score=72, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 288948; Mature: 288816

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQATEIQDIYPLSYMQEGMLFHSLLDSGSNAYVEQISFTVSGDLCIDTFQKSLDMLVSR
CCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHH
YDIFRTIFIKEVPDLEGPQQVVLSRRDTAVQTENISDYSEERQQSIIEEFKETDRHKGFD
HHHHHHHHHHHCCCCCCCHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCC
LQKGPLMRLALFQTGENRHTCVWTHHHIMMDGWSLGIVLKDFFSMYYAIRNGRPVNLGSP
CCCCCCEEEEEEECCCCCCEEEEEECEEEECCCHHHHHHHHHHHHHHHHCCCCEECCCCC
APYSSYIKWLRSRNKEETSAFWSRCLEDYGEVVSVPQTKNKPAQNGYASEHFQFSLESET
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEECHHH
VQKLTDIARSTGVTLNTLFTSIWGLLLHRYNGTEDAVFGSVVSGRPSAIAGIESMAGLFI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
NTVPVRVRAAGDMTFSSLLKKVQKESLAAEEHSYYPLYDIQNESGLQKDLLNHILVFENY
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHEEEECCC
PVQMQTAVNGWKQTESSALSLENFSMAEETNYDLNVVIVPGEEFYVKFSYNAGIYDREDM
CEEEHHHHCCHHHCCHHHEEHHCCCCHHCCCCCEEEEEECCCEEEEEEECCCCCCCHHHH
KRIKGHILEVISCVTEDPDRLLSSISLVPPEEEALIHSFNETNRPYPETTVHGLFEEQAA
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
KTPDQEALRYNGVSWSYKKLNQRANQIAHALREKGARPDQITAVMLRRSMSTVAALLGIW
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
KSGSAYMPIDAEFPPERISFLLRDSEASLLVTEKDLLPLIPPHFKGSVVIMEETVSQQTA
CCCCEECCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCEEEEECHHHHCCC
PLPPVSDSGNWAYVIYTSGTTGRPKGVLVQHKAISNTLQWRREEYGMTEGDIALHLFSYV
CCCCCCCCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
FDGSLTSLFTPLLSGACVLLTDEDDAKDVLSIKQKITRHGVSHLLIVPSLYRVLLDSLTK
HCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
KDAQTLRAVTFAGEAATPDIVEASRGICPNAELLNEYGPTENSVATTILRNLQKSSRITI
HHHHHHHHHEECCCCCCCHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCEEE
GRPIANTSVYIMHGDRLQPVGAVGELCISGKGLADGYFQQKELTDKVFTPHPFREGERLY
ECCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHH
RTGDAARFLPDGTIEYMGRFDDQVKVRGYRIELGEIETALRSLSGVKEAAVTVRKMADGE
HCCCCHHCCCCCHHHHHHCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QELAAYVVLENAGVTFKPHAELAGRLPAYMIPGSFTKLTEMPLSVSGKLDRAALPEPKEA
HHHEEEEEEECCCCEECCCHHHHCCCCCEECCCCCHHHHCCCCCCCCCCCCCCCCCCHHH
ERTGDYQAPRTMLETELLSIWQEVLKREHISMRDDFFQIGGQSLKAASLVSNIHKRLQIE
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LAVRHVFEHPTIESMARFLEQRKRGEYAEITPAVAKDLYPLSFAQKRLYALHQLAADSTG
HHHHHHHCCCCHHHHHHHHHHHHCCCCHHCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
YHMPACLELSGRLNRDRLHEAFSALLQRHEALRTSFVLRNGEPMQHIHAHVDLDLTEIHM
CCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEC
PSGNLLQEVMETFVKPFDVEKAPLLRVTLAKVTEERHFLLLDMHHLIADGVSMSVLIQEL
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHCCCHHHHHHHHH
TDLYRGKELRPLKLQYKDFSVWQHERFAAEEFKRHERYWLETIGENIPVLDLPLDKKRPP
HHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCC
LPDFSGSVVRTRLQKETAENLRQLMDETGSTLYMILLASYSLFLSKLSGQEDIVVGSPAA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
GRSRAELDGVIGMFVNTVAMRSRPKGDKTFRAYLEEVKMLALGAAEHQDFPFEELAQKLD
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
THREVNRNPLFDAMLVLQNSDDFEVNLPGLSVSSHAVKHDISKFDLTLHAEERPDGSLDF
HHHHCCCCCHHHHHEEEECCCCCEEECCCCCCCHHHHHHHHHHEEEEEEECCCCCCCEEE
HFEYSTALFEKDTIERWAGHFKELLGQIASDYERKLSDIHLLGINERQMLLQAENQTAEY
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHEEECCCCCCC
PRHETIVSLFEAQAEKMPNQIAAVMSHERLTYRELNEKADRIADMLSENGIRSGQIVGIM
CHHHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
TERSPDMLIGILGILKAGGAYLPIDPDYPDERISFMLTDSGARALLTQSGLGISGMDGLP
ECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCEEEHCCCCCCCCCCCCCE
VLYIDKPESVSADRTKEMITPEQPAYVIYTSGTTGKPKGVMTEHRNVISLITHKGLPFDF
EEEECCCCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
GSEDVWTLFHSYCFDFSVWEIFGALLYGGKVVIVPKDTARDPHLYRQLLQSEGVTVLNQT
CCHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCEEEECC
PTAFSGLIHEEAGHTDKLKLRYVIFGGEALQPGMLKSWKEKYPETELVNMYGITETTVHV
CHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCEEEEEE
TCKKLNMDDIERNKSNIGRPLETLHAFVMDAYMNPQPIGIPGELYIGGEGVARGYVNRDD
EEEECCHHHHHHCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHCCCCCCCC
LTASRFITNPHVSGMRLYRTGDIAKRLLNGELEYVGRKDAQVKVRGHRIELGEIKSALQE
CCHHHHCCCCCCCCEEEEECHHHHHHHHCCCHHCCCCCCCEEEEECCEEEHHHHHHHHHH
LSSVKEAAVITRADQHGQHSIYAYAVLHGNEKIKEAEIQASLRAFLPEYMIPARLIALDE
HHHHHHHHHHHCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHEEEEC
LPLTANGKLDEKALPQPELNDSLGDDISLRNETEEMMADIWEELLGVEGLGPNAHFFHLG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
GDSIKALQVCARLKQQGYETTVRELFEHQTLGEVSMRLRKVRRVIDQAPVTGDVPLTPIQ
CCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
HWFLSQSLPHDHFNQSVMLRSADRINESAMRKALAQLAVHHDALRIVCGTQNGSVTQYNR
HHHHHCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCEEECCH
AENLSEEELFTFETHDVRGKGSLQEEHVAIEQAAARIQTSIRLETGPLVAVGLFHANDGD
HCCCCHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEECCCCC
HLLLSIHHLVIDGVSWRILFEDLTACYRQALEGKETALPAKTDSYQTYAKQISDYAKSRR
EEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LLQEADYWSEREKMAVEPLPKDARISSNLLKDTDVMTVKLTKQETEQLLTEANRAYTTET
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCCCCH
GELLLAALSLALNRWTGNETFKISMEGHGREEHLEHLDISRTIGWFTSIYPVLVDASFQD
HHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QADDGERLGYHIKRTKDMMRRIPHKGAGYGVLKYISKLWEETESDSPEISFNYLGQFDRE
CCCCCHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHH
IRSSGFGVSPVKAGNEVSPDWERPYTLDISGSVSSECLSMHVVYNRFQYQKETIEVLTGY
HHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHAFLKQIISHCTGKEEREWSAADFSDEELTLEDLSDIMGAVNKL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQATEIQDIYPLSYMQEGMLFHSLLDSGSNAYVEQISFTVSGDLCIDTFQKSLDMLVSR
CCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHH
YDIFRTIFIKEVPDLEGPQQVVLSRRDTAVQTENISDYSEERQQSIIEEFKETDRHKGFD
HHHHHHHHHHHCCCCCCCHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCC
LQKGPLMRLALFQTGENRHTCVWTHHHIMMDGWSLGIVLKDFFSMYYAIRNGRPVNLGSP
CCCCCCEEEEEEECCCCCCEEEEEECEEEECCCHHHHHHHHHHHHHHHHCCCCEECCCCC
APYSSYIKWLRSRNKEETSAFWSRCLEDYGEVVSVPQTKNKPAQNGYASEHFQFSLESET
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEECHHH
VQKLTDIARSTGVTLNTLFTSIWGLLLHRYNGTEDAVFGSVVSGRPSAIAGIESMAGLFI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
NTVPVRVRAAGDMTFSSLLKKVQKESLAAEEHSYYPLYDIQNESGLQKDLLNHILVFENY
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHEEEECCC
PVQMQTAVNGWKQTESSALSLENFSMAEETNYDLNVVIVPGEEFYVKFSYNAGIYDREDM
CEEEHHHHCCHHHCCHHHEEHHCCCCHHCCCCCEEEEEECCCEEEEEEECCCCCCCHHHH
KRIKGHILEVISCVTEDPDRLLSSISLVPPEEEALIHSFNETNRPYPETTVHGLFEEQAA
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
KTPDQEALRYNGVSWSYKKLNQRANQIAHALREKGARPDQITAVMLRRSMSTVAALLGIW
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
KSGSAYMPIDAEFPPERISFLLRDSEASLLVTEKDLLPLIPPHFKGSVVIMEETVSQQTA
CCCCEECCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCEEEEECHHHHCCC
PLPPVSDSGNWAYVIYTSGTTGRPKGVLVQHKAISNTLQWRREEYGMTEGDIALHLFSYV
CCCCCCCCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
FDGSLTSLFTPLLSGACVLLTDEDDAKDVLSIKQKITRHGVSHLLIVPSLYRVLLDSLTK
HCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
KDAQTLRAVTFAGEAATPDIVEASRGICPNAELLNEYGPTENSVATTILRNLQKSSRITI
HHHHHHHHHEECCCCCCCHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCEEE
GRPIANTSVYIMHGDRLQPVGAVGELCISGKGLADGYFQQKELTDKVFTPHPFREGERLY
ECCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHH
RTGDAARFLPDGTIEYMGRFDDQVKVRGYRIELGEIETALRSLSGVKEAAVTVRKMADGE
HCCCCHHCCCCCHHHHHHCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QELAAYVVLENAGVTFKPHAELAGRLPAYMIPGSFTKLTEMPLSVSGKLDRAALPEPKEA
HHHEEEEEEECCCCEECCCHHHHCCCCCEECCCCCHHHHCCCCCCCCCCCCCCCCCCHHH
ERTGDYQAPRTMLETELLSIWQEVLKREHISMRDDFFQIGGQSLKAASLVSNIHKRLQIE
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LAVRHVFEHPTIESMARFLEQRKRGEYAEITPAVAKDLYPLSFAQKRLYALHQLAADSTG
HHHHHHHCCCCHHHHHHHHHHHHCCCCHHCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
YHMPACLELSGRLNRDRLHEAFSALLQRHEALRTSFVLRNGEPMQHIHAHVDLDLTEIHM
CCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEC
PSGNLLQEVMETFVKPFDVEKAPLLRVTLAKVTEERHFLLLDMHHLIADGVSMSVLIQEL
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHCCCHHHHHHHHH
TDLYRGKELRPLKLQYKDFSVWQHERFAAEEFKRHERYWLETIGENIPVLDLPLDKKRPP
HHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCC
LPDFSGSVVRTRLQKETAENLRQLMDETGSTLYMILLASYSLFLSKLSGQEDIVVGSPAA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
GRSRAELDGVIGMFVNTVAMRSRPKGDKTFRAYLEEVKMLALGAAEHQDFPFEELAQKLD
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
THREVNRNPLFDAMLVLQNSDDFEVNLPGLSVSSHAVKHDISKFDLTLHAEERPDGSLDF
HHHHCCCCCHHHHHEEEECCCCCEEECCCCCCCHHHHHHHHHHEEEEEEECCCCCCCEEE
HFEYSTALFEKDTIERWAGHFKELLGQIASDYERKLSDIHLLGINERQMLLQAENQTAEY
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHEEECCCCCCC
PRHETIVSLFEAQAEKMPNQIAAVMSHERLTYRELNEKADRIADMLSENGIRSGQIVGIM
CHHHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
TERSPDMLIGILGILKAGGAYLPIDPDYPDERISFMLTDSGARALLTQSGLGISGMDGLP
ECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCEEEHCCCCCCCCCCCCCE
VLYIDKPESVSADRTKEMITPEQPAYVIYTSGTTGKPKGVMTEHRNVISLITHKGLPFDF
EEEECCCCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
GSEDVWTLFHSYCFDFSVWEIFGALLYGGKVVIVPKDTARDPHLYRQLLQSEGVTVLNQT
CCHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCEEEECC
PTAFSGLIHEEAGHTDKLKLRYVIFGGEALQPGMLKSWKEKYPETELVNMYGITETTVHV
CHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCEEEEEE
TCKKLNMDDIERNKSNIGRPLETLHAFVMDAYMNPQPIGIPGELYIGGEGVARGYVNRDD
EEEECCHHHHHHCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHCCCCCCCC
LTASRFITNPHVSGMRLYRTGDIAKRLLNGELEYVGRKDAQVKVRGHRIELGEIKSALQE
CCHHHHCCCCCCCCEEEEECHHHHHHHHCCCHHCCCCCCCEEEEECCEEEHHHHHHHHHH
LSSVKEAAVITRADQHGQHSIYAYAVLHGNEKIKEAEIQASLRAFLPEYMIPARLIALDE
HHHHHHHHHHHCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHEEEEC
LPLTANGKLDEKALPQPELNDSLGDDISLRNETEEMMADIWEELLGVEGLGPNAHFFHLG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
GDSIKALQVCARLKQQGYETTVRELFEHQTLGEVSMRLRKVRRVIDQAPVTGDVPLTPIQ
CCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
HWFLSQSLPHDHFNQSVMLRSADRINESAMRKALAQLAVHHDALRIVCGTQNGSVTQYNR
HHHHHCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCEEECCH
AENLSEEELFTFETHDVRGKGSLQEEHVAIEQAAARIQTSIRLETGPLVAVGLFHANDGD
HCCCCHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEECCCCC
HLLLSIHHLVIDGVSWRILFEDLTACYRQALEGKETALPAKTDSYQTYAKQISDYAKSRR
EEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LLQEADYWSEREKMAVEPLPKDARISSNLLKDTDVMTVKLTKQETEQLLTEANRAYTTET
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCCCCH
GELLLAALSLALNRWTGNETFKISMEGHGREEHLEHLDISRTIGWFTSIYPVLVDASFQD
HHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QADDGERLGYHIKRTKDMMRRIPHKGAGYGVLKYISKLWEETESDSPEISFNYLGQFDRE
CCCCCHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHH
IRSSGFGVSPVKAGNEVSPDWERPYTLDISGSVSSECLSMHVVYNRFQYQKETIEVLTGY
HHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHAFLKQIISHCTGKEEREWSAADFSDEELTLEDLSDIMGAVNKL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7711903; 9384377; 10471562 [H]