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The map label for this gene is yvrG [H]

Identifier: 154686245

GI number: 154686245

Start: 1865725

End: 1867122

Strand: Reverse

Name: yvrG [H]

Synonym: RBAM_018120

Alternate gene names: 154686245

Gene position: 1867122-1865725 (Counterclockwise)

Preceding gene: 154686246

Following gene: 154686243

Centisome position: 47.65

GC content: 38.63

Gene sequence:

>1398_bases
ATGAATTGGCGATTAACAGGCAGATATATGGTCTCTGTCATTATCGTGACCATCATTACAGTTTTCATTAATTTATTTAT
TTTTATGTTTTGGCTCGTTTTCCAGGCGAACAGCCAACATGACGAAGAAAGTACACCGGAAACTTTCACAAGATCATTCC
GACAATATGTCACGTTATCGAACAATGGTATCACAGTAAACAAAGAGGGCCAAAAAGCTTTAAAAGAGCAGAATGCATGG
ATTCAAATATTAGATGAAAACGGACAGGATGTTTATCATGATAGAGAACCTAAAGGACTGAAGAAAAAATATACGCCTAT
TGAAATTGTAAATTTACATAAATATAAGGATGAACGATTATTATCAACCATTTACGCCGGCGGAAAAAAAGTAAACGGCA
AGGAGTACAGTTACTTTATAGGGTTTAAAAATCCCTCTCTCGGAAAATATGTCCTCTCATATGATACCAAGGAATTTGTG
ACGAAGTTCAATGCAGGAACCATCATATTATTATCAATAGATGCATTGATCGCGTTACTCATTGGCTATCTATTCAGCCG
GCAGCTCACAAAACCGCTCGGCCGTGTCATTCAAGGAATCCAGCGGTTAGCTAATGGAGATTATACGATCAAAATGAAAT
CCAAAGGCATTTATAAAGATGTCTTCTATAATGTCAATCATTTATCGGAACAACTATCTTCAAGCAAAAAAGAAAAAGAT
AAATTAGAGCAAATGCGTGAAGAGTGGATCAGTCATATTTCTCATGACATTAAAACACCATTAGCATCTATTCAAGGCTA
TGCAGAAATCATCCAAGATCCAAATTACCATCTAACAGCCGAACAGATCAGAGAGTACGCCCAGATCATTGAGAGTAAAT
CCCTCTATATGAAAGATGTGATGGAAGATTTAAATTTAACGACAAGGCTGAAAAACAACGATGTGATGTTACATACAGAA
CGGGTAAACCTTGTATCGCTGCTGCGGGAAACGTTAATTGATATGTTAAACGATTCTAGATATGCGGATAAGTCCATTGA
GCTTCAAACGAACGTGGAAAAGCTGATGCTGAACCTTGATGCGATATTGATTAGGAGAGCGGTCACGAATCTCATTTTAA
ATGCCCTCGTTCACAATGATCCTGATGTGAAGATCGTTGTACAGCTTGAACAAAAAGAACGGACTCATGTGACAATTAAG
GACAACGGCAAAGGGATAGAAGAAGAGGAGCTGGAAAAAGTGTTTGATCGCTATTACAGGGGCACAAATACAGAAACGAC
GCATGCAGGCTCTGGTCTTGGAATGGCCATAGCAAAGGATATTATCCAAAAGCACGGAGGGGACATCACCATTCACAGCA
CCGCGGGAGAAGGGACAACGATAGATATACAATTATGA

Upstream 100 bases:

>100_bases
GCAGGCTCCGTGAGAAAATAGAAAACACCCCATCAAAACCAGACTTTCTCGTCACTGTGAAAGGGTTAGGCTACAAATTT
GTTGTAAAGGATGCGTAAGG

Downstream 100 bases:

>100_bases
TAATGGCTATACAAAAAACGGTTCTGTTGATTAATAACAGAACCGTTTTTTCCTATTGTTCCGAAAACACTTTGATTCCT
TTGACAATGTTCCAAATGAA

Product: YvrG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MNWRLTGRYMVSVIIVTIITVFINLFIFMFWLVFQANSQHDEESTPETFTRSFRQYVTLSNNGITVNKEGQKALKEQNAW
IQILDENGQDVYHDREPKGLKKKYTPIEIVNLHKYKDERLLSTIYAGGKKVNGKEYSYFIGFKNPSLGKYVLSYDTKEFV
TKFNAGTIILLSIDALIALLIGYLFSRQLTKPLGRVIQGIQRLANGDYTIKMKSKGIYKDVFYNVNHLSEQLSSSKKEKD
KLEQMREEWISHISHDIKTPLASIQGYAEIIQDPNYHLTAEQIREYAQIIESKSLYMKDVMEDLNLTTRLKNNDVMLHTE
RVNLVSLLRETLIDMLNDSRYADKSIELQTNVEKLMLNLDAILIRRAVTNLILNALVHNDPDVKIVVQLEQKERTHVTIK
DNGKGIEEEELEKVFDRYYRGTNTETTHAGSGLGMAIAKDIIQKHGGDITIHSTAGEGTTIDIQL

Sequences:

>Translated_465_residues
MNWRLTGRYMVSVIIVTIITVFINLFIFMFWLVFQANSQHDEESTPETFTRSFRQYVTLSNNGITVNKEGQKALKEQNAW
IQILDENGQDVYHDREPKGLKKKYTPIEIVNLHKYKDERLLSTIYAGGKKVNGKEYSYFIGFKNPSLGKYVLSYDTKEFV
TKFNAGTIILLSIDALIALLIGYLFSRQLTKPLGRVIQGIQRLANGDYTIKMKSKGIYKDVFYNVNHLSEQLSSSKKEKD
KLEQMREEWISHISHDIKTPLASIQGYAEIIQDPNYHLTAEQIREYAQIIESKSLYMKDVMEDLNLTTRLKNNDVMLHTE
RVNLVSLLRETLIDMLNDSRYADKSIELQTNVEKLMLNLDAILIRRAVTNLILNALVHNDPDVKIVVQLEQKERTHVTIK
DNGKGIEEEELEKVFDRYYRGTNTETTHAGSGLGMAIAKDIIQKHGGDITIHSTAGEGTTIDIQL
>Mature_465_residues
MNWRLTGRYMVSVIIVTIITVFINLFIFMFWLVFQANSQHDEESTPETFTRSFRQYVTLSNNGITVNKEGQKALKEQNAW
IQILDENGQDVYHDREPKGLKKKYTPIEIVNLHKYKDERLLSTIYAGGKKVNGKEYSYFIGFKNPSLGKYVLSYDTKEFV
TKFNAGTIILLSIDALIALLIGYLFSRQLTKPLGRVIQGIQRLANGDYTIKMKSKGIYKDVFYNVNHLSEQLSSSKKEKD
KLEQMREEWISHISHDIKTPLASIQGYAEIIQDPNYHLTAEQIREYAQIIESKSLYMKDVMEDLNLTTRLKNNDVMLHTE
RVNLVSLLRETLIDMLNDSRYADKSIELQTNVEKLMLNLDAILIRRAVTNLILNALVHNDPDVKIVVQLEQKERTHVTIK
DNGKGIEEEELEKVFDRYYRGTNTETTHAGSGLGMAIAKDIIQKHGGDITIHSTAGEGTTIDIQL

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon. Probably activates yv

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=283, Percent_Identity=27.208480565371, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=28.2157676348548, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082128, Length=296, Percent_Identity=26.0135135135135, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081816, Length=331, Percent_Identity=25.9818731117825, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=26.6375545851528, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789149, Length=362, Percent_Identity=22.6519337016575, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788713, Length=242, Percent_Identity=26.8595041322314, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1790861, Length=244, Percent_Identity=25, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=25.6198347107438, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786783, Length=303, Percent_Identity=23.1023102310231, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=243, Percent_Identity=25.5144032921811, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789808, Length=298, Percent_Identity=23.489932885906, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=21.4876033057851, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=478, Percent_Identity=22.3849372384937, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788279, Length=220, Percent_Identity=25, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787894, Length=316, Percent_Identity=21.5189873417722, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790346, Length=218, Percent_Identity=24.3119266055046, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53392; Mature: 53392

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWRLTGRYMVSVIIVTIITVFINLFIFMFWLVFQANSQHDEESTPETFTRSFRQYVTLS
CCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEEEC
NNGITVNKEGQKALKEQNAWIQILDENGQDVYHDREPKGLKKKYTPIEIVNLHKYKDERL
CCCEEECCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHH
LSTIYAGGKKVNGKEYSYFIGFKNPSLGKYVLSYDTKEFVTKFNAGTIILLSIDALIALL
HHHHHCCCCCCCCCEEEEEEEECCCCCCCEEEECCHHHHHHHCCCCEEEEEEHHHHHHHH
IGYLFSRQLTKPLGRVIQGIQRLANGDYTIKMKSKGIYKDVFYNVNHLSEQLSSSKKEKD
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
KLEQMREEWISHISHDIKTPLASIQGYAEIIQDPNYHLTAEQIREYAQIIESKSLYMKDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHH
MEDLNLTTRLKNNDVMLHTERVNLVSLLRETLIDMLNDSRYADKSIELQTNVEKLMLNLD
HHHCCHHEEECCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHH
AILIRRAVTNLILNALVHNDPDVKIVVQLEQKERTHVTIKDNGKGIEEEELEKVFDRYYR
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHC
GTNTETTHAGSGLGMAIAKDIIQKHGGDITIHSTAGEGTTIDIQL
CCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEC
>Mature Secondary Structure
MNWRLTGRYMVSVIIVTIITVFINLFIFMFWLVFQANSQHDEESTPETFTRSFRQYVTLS
CCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEEEC
NNGITVNKEGQKALKEQNAWIQILDENGQDVYHDREPKGLKKKYTPIEIVNLHKYKDERL
CCCEEECCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHH
LSTIYAGGKKVNGKEYSYFIGFKNPSLGKYVLSYDTKEFVTKFNAGTIILLSIDALIALL
HHHHHCCCCCCCCCEEEEEEEECCCCCCCEEEECCHHHHHHHCCCCEEEEEEHHHHHHHH
IGYLFSRQLTKPLGRVIQGIQRLANGDYTIKMKSKGIYKDVFYNVNHLSEQLSSSKKEKD
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
KLEQMREEWISHISHDIKTPLASIQGYAEIIQDPNYHLTAEQIREYAQIIESKSLYMKDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHH
MEDLNLTTRLKNNDVMLHTERVNLVSLLRETLIDMLNDSRYADKSIELQTNVEKLMLNLD
HHHCCHHEEECCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHH
AILIRRAVTNLILNALVHNDPDVKIVVQLEQKERTHVTIKDNGKGIEEEELEKVFDRYYR
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHC
GTNTETTHAGSGLGMAIAKDIIQKHGGDITIHSTAGEGTTIDIQL
CCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]