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The map label for this gene is yvrH [H]

Identifier: 154686246

GI number: 154686246

Start: 1867125

End: 1867928

Strand: Reverse

Name: yvrH [H]

Synonym: RBAM_018130

Alternate gene names: 154686246

Gene position: 1867928-1867125 (Counterclockwise)

Preceding gene: 154686247

Following gene: 154686245

Centisome position: 47.67

GC content: 41.92

Gene sequence:

>804_bases
TTGGCTTATTTTCTGTGGGAGAGAAGTGTTGATTTTTTTAACGATACACAGACATTGGGTATAATAATGACAATGACTTC
AAGGAGTGATCAATATATGTCACGGCTTCACAGCAAAGTATTAATCATAGACGACGAAAAAGAAATTTTGGAACTGATCA
AAACCGTATTAATAAGAGAAGGCATTGATCGCGTAGTGACCGCTTCGACTGCCCGTGACGGATTGGCTCAATTTCATCAA
GAAAATCCCGATCTGGTGATATTGGATATCATGCTGCCAGACGGTGAAGGCTATGATATCTGCAAGCAAATAAGAGACAT
TTCACACGTTCCTATTATCTTTTTGTCTGCAAAGGGGGAGGAAACGGATAAAATTGTAGGGCTTGCCATCGGCGGGGACG
ACTACATTACAAAACCCTTCAGCCCTAAGGAAGTTGCATATCGAGTCAAAGCGCAGCTGAGACGGGTCTCTTACTTACAG
CCTTCTCAAACCGGAACCATAATAAAAAAAGGGCCATTTGAGTTAAACCAACAACAAGCCGAGCTCACCAAAAATGAAGC
GGCTATTGAGTTAACACCTAAAGAACTTATGCTTATGACCTATTTTCTGCAGCATCCCAATCGGGTGATCAGTAAAGAAA
CACTCTATCAAGCTGTATGGGGAGAAGATTTCTTCGGTTCTGACAACACGGTGATGGTTCATATACGCAGGCTCCGTGAG
AAAATAGAAAACACCCCATCAAAACCAGACTTTCTCGTCACTGTGAAAGGGTTAGGCTACAAATTTGTTGTAAAGGATGC
GTAA

Upstream 100 bases:

>100_bases
TTTGGGCCCATCTGCCGGCTCAAAGCGTGACAACATTTGTTGTAAAGCGTTAAAGGCATCAGCATCGCAATAAGCCAATT
TTCTTACTCAAAAAAGAAAA

Downstream 100 bases:

>100_bases
GGATGAATTGGCGATTAACAGGCAGATATATGGTCTCTGTCATTATCGTGACCATCATTACAGTTTTCATTAATTTATTT
ATTTTTATGTTTTGGCTCGT

Product: YvrH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MAYFLWERSVDFFNDTQTLGIIMTMTSRSDQYMSRLHSKVLIIDDEKEILELIKTVLIREGIDRVVTASTARDGLAQFHQ
ENPDLVILDIMLPDGEGYDICKQIRDISHVPIIFLSAKGEETDKIVGLAIGGDDYITKPFSPKEVAYRVKAQLRRVSYLQ
PSQTGTIIKKGPFELNQQQAELTKNEAAIELTPKELMLMTYFLQHPNRVISKETLYQAVWGEDFFGSDNTVMVHIRRLRE
KIENTPSKPDFLVTVKGLGYKFVVKDA

Sequences:

>Translated_267_residues
MAYFLWERSVDFFNDTQTLGIIMTMTSRSDQYMSRLHSKVLIIDDEKEILELIKTVLIREGIDRVVTASTARDGLAQFHQ
ENPDLVILDIMLPDGEGYDICKQIRDISHVPIIFLSAKGEETDKIVGLAIGGDDYITKPFSPKEVAYRVKAQLRRVSYLQ
PSQTGTIIKKGPFELNQQQAELTKNEAAIELTPKELMLMTYFLQHPNRVISKETLYQAVWGEDFFGSDNTVMVHIRRLRE
KIENTPSKPDFLVTVKGLGYKFVVKDA
>Mature_266_residues
AYFLWERSVDFFNDTQTLGIIMTMTSRSDQYMSRLHSKVLIIDDEKEILELIKTVLIREGIDRVVTASTARDGLAQFHQE
NPDLVILDIMLPDGEGYDICKQIRDISHVPIIFLSAKGEETDKIVGLAIGGDDYITKPFSPKEVAYRVKAQLRRVSYLQP
SQTGTIIKKGPFELNQQQAELTKNEAAIELTPKELMLMTYFLQHPNRVISKETLYQAVWGEDFFGSDNTVMVHIRRLREK
IENTPSKPDFLVTVKGLGYKFVVKDA

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=38.961038961039, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=36.9565217391304, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=33.920704845815, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=35.2678571428571, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=34.4978165938865, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=33.0396475770925, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1786784, Length=238, Percent_Identity=33.6134453781513, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=33.0472103004292, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=32.3275862068966, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=32.4675324675325, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=33.6206896551724, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=31.0043668122271, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=30.6666666666667, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=25.9574468085106, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=175, Percent_Identity=25.1428571428571, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 30506; Mature: 30374

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYFLWERSVDFFNDTQTLGIIMTMTSRSDQYMSRLHSKVLIIDDEKEILELIKTVLIRE
CEEEEEECCCCCCCCCCEEEEEEEEECCCHHHHHHHCCEEEEEECCHHHHHHHHHHHHHH
GIDRVVTASTARDGLAQFHQENPDLVILDIMLPDGEGYDICKQIRDISHVPIIFLSAKGE
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCEEEEECCCC
ETDKIVGLAIGGDDYITKPFSPKEVAYRVKAQLRRVSYLQPSQTGTIIKKGPFELNQQQA
CCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHH
ELTKNEAAIELTPKELMLMTYFLQHPNRVISKETLYQAVWGEDFFGSDNTVMVHIRRLRE
HHHCCCCEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHH
KIENTPSKPDFLVTVKGLGYKFVVKDA
HHHCCCCCCCEEEEEECCCEEEEEECC
>Mature Secondary Structure 
AYFLWERSVDFFNDTQTLGIIMTMTSRSDQYMSRLHSKVLIIDDEKEILELIKTVLIRE
EEEEEECCCCCCCCCCEEEEEEEEECCCHHHHHHHCCEEEEEECCHHHHHHHHHHHHHH
GIDRVVTASTARDGLAQFHQENPDLVILDIMLPDGEGYDICKQIRDISHVPIIFLSAKGE
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCEEEEECCCC
ETDKIVGLAIGGDDYITKPFSPKEVAYRVKAQLRRVSYLQPSQTGTIIKKGPFELNQQQA
CCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHH
ELTKNEAAIELTPKELMLMTYFLQHPNRVISKETLYQAVWGEDFFGSDNTVMVHIRRLRE
HHHCCCCEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHH
KIENTPSKPDFLVTVKGLGYKFVVKDA
HHHCCCCCCCEEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]