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The map label for this gene is ykrU [H]

Identifier: 154685768

GI number: 154685768

Start: 1297673

End: 1298452

Strand: Reverse

Name: ykrU [H]

Synonym: RBAM_013350

Alternate gene names: 154685768

Gene position: 1298452-1297673 (Counterclockwise)

Preceding gene: 154685775

Following gene: 154685767

Centisome position: 33.14

GC content: 49.62

Gene sequence:

>780_bases
ATGAAATGGACCGTTTCCTGTTTGCAATTTGATATTTCATACGGAAATCCTTCAGAAAACTTTAAAAAAGCAGAATCTTT
GATTGAGCAAGAAAGCCGCCATGCGGATGTAATCGTGCTTCCTGAGTTGTGGACGACCGGCTATGATCTCACACGGCTAG
ACCAGCTGGCGGATGAAAACGGCAAAGTTTCAGAACAATGGCTTAAAGAAACGGCAAAAACATACAACGTACACCTCGTT
GCCGGATCTTTTGCGGTCAAAGAAGGCGAAAATGTCTATAACACCATGTACATCGCCGATAACAGCGGACAGATCGTGAA
GCGGTATCAGAAAGCCCATCTGTTTCAGCTGATGGATGAACACCTTTACTTGTCAGCAGGAAACAGCGACGGTTCCTTTG
AGCTTGACGGTGTCAAGTGCGCCGGGCTGATCTGCTATGATATCCGTTTCCCCGAATGGATCAGAAAGCATACGTCCCAG
GGCGCGAATGTCCTGTTTATCTCTGCGGAATGGCCTCTGCCCCGCCTTGATCATTGGCGAAGCCTGCTTATCGCCAGAGC
AATTGAAAACCAATGTTTTGTCGCAGCCTCTAACTGCACGGGGTCCAATCCCGATAATGAATTTGCCGGCCACAGCCTGA
TTATTGACCCGTGGGGCCGGATTTTAGCCGAAAGAGACCGGACGGAAGGCGCAGTCCGGGCGGAAATCGATGTGTCAGAA
AGCGCGGCCGTGCGGGGAACCATTCCGGTTTTCCAAGACTTGCGGCGTGATTTATATTAA

Upstream 100 bases:

>100_bases
AAAGTTCATATTTTCACCTTCTAAAAATGTCTTGAAATGATAGTCCATCATCATATATGGTTAAATAACAAAAGTAAAGA
GAAACTTGAGGTGTTAAAAA

Downstream 100 bases:

>100_bases
TTTTCAAAAAAACGTTGACAAGAATATCCGGCACCTGCTAATATTTTCATCAACTGATTAATCCGAATTGTGATACAAAT
CAATATATTTTTCTCTTATC

Product: YkrU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKWTVSCLQFDISYGNPSENFKKAESLIEQESRHADVIVLPELWTTGYDLTRLDQLADENGKVSEQWLKETAKTYNVHLV
AGSFAVKEGENVYNTMYIADNSGQIVKRYQKAHLFQLMDEHLYLSAGNSDGSFELDGVKCAGLICYDIRFPEWIRKHTSQ
GANVLFISAEWPLPRLDHWRSLLIARAIENQCFVAASNCTGSNPDNEFAGHSLIIDPWGRILAERDRTEGAVRAEIDVSE
SAAVRGTIPVFQDLRRDLY

Sequences:

>Translated_259_residues
MKWTVSCLQFDISYGNPSENFKKAESLIEQESRHADVIVLPELWTTGYDLTRLDQLADENGKVSEQWLKETAKTYNVHLV
AGSFAVKEGENVYNTMYIADNSGQIVKRYQKAHLFQLMDEHLYLSAGNSDGSFELDGVKCAGLICYDIRFPEWIRKHTSQ
GANVLFISAEWPLPRLDHWRSLLIARAIENQCFVAASNCTGSNPDNEFAGHSLIIDPWGRILAERDRTEGAVRAEIDVSE
SAAVRGTIPVFQDLRRDLY
>Mature_259_residues
MKWTVSCLQFDISYGNPSENFKKAESLIEQESRHADVIVLPELWTTGYDLTRLDQLADENGKVSEQWLKETAKTYNVHLV
AGSFAVKEGENVYNTMYIADNSGQIVKRYQKAHLFQLMDEHLYLSAGNSDGSFELDGVKCAGLICYDIRFPEWIRKHTSQ
GANVLFISAEWPLPRLDHWRSLLIARAIENQCFVAASNCTGSNPDNEFAGHSLIIDPWGRILAERDRTEGAVRAEIDVSE
SAAVRGTIPVFQDLRRDLY

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=267, Percent_Identity=30.3370786516854, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI5031947, Length=259, Percent_Identity=28.957528957529, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI297632350, Length=259, Percent_Identity=28.957528957529, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI297632348, Length=259, Percent_Identity=28.957528957529, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI1786412, Length=251, Percent_Identity=33.0677290836653, Blast_Score=129, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17556280, Length=259, Percent_Identity=33.976833976834, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323383, Length=280, Percent_Identity=26.7857142857143, Blast_Score=104, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6322335, Length=294, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21355835, Length=239, Percent_Identity=32.2175732217573, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI17933642, Length=260, Percent_Identity=29.6153846153846, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 29320; Mature: 29320

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWTVSCLQFDISYGNPSENFKKAESLIEQESRHADVIVLPELWTTGYDLTRLDQLADEN
CCEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCCC
GKVSEQWLKETAKTYNVHLVAGSFAVKEGENVYNTMYIADNSGQIVKRYQKAHLFQLMDE
CCHHHHHHHHHHHHEEEEEEECCEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHH
HLYLSAGNSDGSFELDGVKCAGLICYDIRFPEWIRKHTSQGANVLFISAEWPLPRLDHWR
HEEEEECCCCCCEEECCEEEEEEEEEECCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHH
SLLIARAIENQCFVAASNCTGSNPDNEFAGHSLIIDPWGRILAERDRTEGAVRAEIDVSE
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCCCCEEEEEECCC
SAAVRGTIPVFQDLRRDLY
CCEEECCCHHHHHHHHHCC
>Mature Secondary Structure
MKWTVSCLQFDISYGNPSENFKKAESLIEQESRHADVIVLPELWTTGYDLTRLDQLADEN
CCEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCCC
GKVSEQWLKETAKTYNVHLVAGSFAVKEGENVYNTMYIADNSGQIVKRYQKAHLFQLMDE
CCHHHHHHHHHHHHEEEEEEECCEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHH
HLYLSAGNSDGSFELDGVKCAGLICYDIRFPEWIRKHTSQGANVLFISAEWPLPRLDHWR
HEEEEECCCCCCEEECCEEEEEEEEEECCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHH
SLLIARAIENQCFVAASNCTGSNPDNEFAGHSLIIDPWGRILAERDRTEGAVRAEIDVSE
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCCCCEEEEEECCC
SAAVRGTIPVFQDLRRDLY
CCEEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]