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The map label for this gene is aroD

Identifier: 154685262

GI number: 154685262

Start: 799997

End: 800758

Strand: Reverse

Name: aroD

Synonym: RBAM_008080

Alternate gene names: 154685262

Gene position: 800758-799997 (Counterclockwise)

Preceding gene: 154685263

Following gene: 154685261

Centisome position: 20.43

GC content: 49.34

Gene sequence:

>762_bases
ATGCAATCTATCACGATCAGAAACACGGTCATCGGCGAAGGGCTTCCGAAGATCATTGTGCCGCTGATGGCGGCCGGAGA
GAAAGAACTGCTCGAAGAAATTGAAGCCGTCAACAGGCTTCGCCCGGATATCATTGAGTGGCGGGCGGATGTGTACGAGC
ATGTTGACAGCCTGGACGCCGTAAAAGACATGCTTGAAATGCTGCGGAAAGCCGCAGGCGCAACACCGCTGCTTTTCACA
TTCAGAACTCATAAAGAAGGCGGAAATAAAGTTATTGATGACCGCTTTTACATTGAATTGCTTAAAACCGCCATCGAAAC
AAAACACATTGACCTTGCAGACGTTGAGTTGTTTACGGGAGAAGCGGAAGTCAAATTAATTGTGAAAACCGCTGAAGACA
ACGGCGTATATGTCGTCATGTCCAATCATGATTTTCATCAGACACCGAAAAAAGAAGAAATCATTTCCCGGCTGCGGAAC
ATGCAGGCGTACGGCGCGCACATTCCGAAAATCGCGGTGATGCCGCAAAGCACTGAAGATGTTTTCGTCTTATTGGATGC
CACTCACACGATGAAAACACAATACGCAGACCGGCCGATCATCACGATGTCAATGGCGGGAACAGGTCTGATCAGCCGCC
TGGCCGGCGAAGTCTTCGGCTCAGCGTGCACGTTCGGAGCGGGCAAAGAAGCATCAGCGCCCGGACAAATTCCCGTTGAA
GAATTGCGCAGCGTACTCAGCATTTTAAATAAACATATGTAA

Upstream 100 bases:

>100_bases
TCGGAATTGCGGCCGTCAGCGCCCTTCTCGCATTGTTTATCGGAATCCGCTTTAAGCAAGTGATGAAAGCCTGACTATTT
TTTAAGGGAGAGGATTTATC

Downstream 100 bases:

>100_bases
TCAGCGTTTTTCTGCCCTTAAAGCGGGATGAAAAACAAATGAATGGACTAACGGAGGAATACATCATGAAGAAAGATTTA
GGACGGATTAACGGAAAAAC

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MQSITIRNTVIGEGLPKIIVPLMAAGEKELLEEIEAVNRLRPDIIEWRADVYEHVDSLDAVKDMLEMLRKAAGATPLLFT
FRTHKEGGNKVIDDRFYIELLKTAIETKHIDLADVELFTGEAEVKLIVKTAEDNGVYVVMSNHDFHQTPKKEEIISRLRN
MQAYGAHIPKIAVMPQSTEDVFVLLDATHTMKTQYADRPIITMSMAGTGLISRLAGEVFGSACTFGAGKEASAPGQIPVE
ELRSVLSILNKHM

Sequences:

>Translated_253_residues
MQSITIRNTVIGEGLPKIIVPLMAAGEKELLEEIEAVNRLRPDIIEWRADVYEHVDSLDAVKDMLEMLRKAAGATPLLFT
FRTHKEGGNKVIDDRFYIELLKTAIETKHIDLADVELFTGEAEVKLIVKTAEDNGVYVVMSNHDFHQTPKKEEIISRLRN
MQAYGAHIPKIAVMPQSTEDVFVLLDATHTMKTQYADRPIITMSMAGTGLISRLAGEVFGSACTFGAGKEASAPGQIPVE
ELRSVLSILNKHM
>Mature_253_residues
MQSITIRNTVIGEGLPKIIVPLMAAGEKELLEEIEAVNRLRPDIIEWRADVYEHVDSLDAVKDMLEMLRKAAGATPLLFT
FRTHKEGGNKVIDDRFYIELLKTAIETKHIDLADVELFTGEAEVKLIVKTAEDNGVYVVMSNHDFHQTPKKEEIISRLRN
MQAYGAHIPKIAVMPQSTEDVFVLLDATHTMKTQYADRPIITMSMAGTGLISRLAGEVFGSACTFGAGKEASAPGQIPVE
ELRSVLSILNKHM

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family

Homologues:

Organism=Escherichia coli, GI1787984, Length=251, Percent_Identity=55.3784860557769, Blast_Score=272, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROD_BACA2 (A7Z2G6)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001420423.1
- ProteinModelPortal:   A7Z2G6
- SMR:   A7Z2G6
- STRING:   A7Z2G6
- EnsemblBacteria:   EBBACT00000007683
- GeneID:   5462832
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_008080
- eggNOG:   COG0710
- GeneTree:   EBGT00050000001972
- HOGENOM:   HBG732926
- OMA:   NHDFDKT
- ProtClustDB:   PRK02412
- BioCyc:   BAMY326423:RBAM_008080-MONOMER
- HAMAP:   MF_00214
- InterPro:   IPR018508
- InterPro:   IPR013785
- InterPro:   IPR001381
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR01093

Pfam domain/function: PF01487 DHquinase_I

EC number: =4.2.1.10

Molecular weight: Translated: 28086; Mature: 28086

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: ACT_SITE 143-143 ACT_SITE 170-170

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSITIRNTVIGEGLPKIIVPLMAAGEKELLEEIEAVNRLRPDIIEWRADVYEHVDSLDA
CCCEEECHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
VKDMLEMLRKAAGATPLLFTFRTHKEGGNKVIDDRFYIELLKTAIETKHIDLADVELFTG
HHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEHEEEEEC
EAEVKLIVKTAEDNGVYVVMSNHDFHQTPKKEEIISRLRNMQAYGAHIPKIAVMPQSTED
CCEEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
VFVLLDATHTMKTQYADRPIITMSMAGTGLISRLAGEVFGSACTFGAGKEASAPGQIPVE
EEEEEECCHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
ELRSVLSILNKHM
HHHHHHHHHHHCC
>Mature Secondary Structure
MQSITIRNTVIGEGLPKIIVPLMAAGEKELLEEIEAVNRLRPDIIEWRADVYEHVDSLDA
CCCEEECHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
VKDMLEMLRKAAGATPLLFTFRTHKEGGNKVIDDRFYIELLKTAIETKHIDLADVELFTG
HHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEHEEEEEC
EAEVKLIVKTAEDNGVYVVMSNHDFHQTPKKEEIISRLRNMQAYGAHIPKIAVMPQSTED
CCEEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
VFVLLDATHTMKTQYADRPIITMSMAGTGLISRLAGEVFGSACTFGAGKEASAPGQIPVE
EEEEEECCHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
ELRSVLSILNKHM
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA