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The map label for this gene is aroE [H]

Identifier: 154685261

GI number: 154685261

Start: 799047

End: 799958

Strand: Reverse

Name: aroE [H]

Synonym: RBAM_008070

Alternate gene names: 154685261

Gene position: 799958-799047 (Counterclockwise)

Preceding gene: 154685262

Following gene: 154685260

Centisome position: 20.41

GC content: 48.36

Gene sequence:

>912_bases
ATGAATGGACTAACGGAGGAATACATCATGAAGAAAGATTTAGGACGGATTAACGGAAAAACTCAGCTTATCGGATTATT
CGCGACACCGATCGGACACTCTTTATCTCCGGCGATGCACAACCTGGCGTTTAAAAAATTAGGATTGAACTACGCGTACC
TCGCGTTTGAAGTCGGCAATGAACAGCTGGAAGATGTGGTAACGGGAATGCGCGCCTTAAACGTCAGAGGCTTCAATGTC
TCGATGCCGAACAAGATGAACATTCTCCCTTACCTCGATGAACTCGCGGATTCAGCGAAATTCACCGGCGCGGTGAATAC
AGTCGTTAATGAAAACGGCAGACTGATCGGACACTCCACTGACGGTATGGGATACGTCCGCAACTTAAAAGAACATGGCA
TCGATATCACAGGCAAAAAAATGACGCTGGTCGGTTCCGGCGGGGCCGCCACTCCGATAGCGATTCAATCCGCATTGGAA
GGCCTCGGAGAAATCTCTATTTTCGCCCGCAATGACGCGTTTTTCGAAAAAGCGGAAGAAAACGTCCGCATCATCAATGA
AGAAATGAAGGGATCTTCTTGCAAAGCGAAAGTCTTCCCGCTCGAAGATCAAGATGCGCTGCGTGCTGAAATCGCTTCAA
GCGATATTTTCACAAACGGAACGGGTGTCGGCATGAAACCGCTTGAAGGCTTGAGCGTCATTGAAGATACATCCATGCTC
CGTCCTGATTTGATTGTGACAGACGTCGTTTACAACCCCGTTACGTCGAAATTGCTTGAACAAGCTCAAGCGGCCGGCTG
CAACACGATTAACGGCCTCGGCATGATGCTTTGGCAGGGCGCCATGGCGTTTGAATATTGGACAGGCCGTGAAATGCCGG
TTCAGTATATTAAAGAGCAAATGTTTGAATAA

Upstream 100 bases:

>100_bases
CCGGACAAATTCCCGTTGAAGAATTGCGCAGCGTACTCAGCATTTTAAATAAACATATGTAATCAGCGTTTTTCTGCCCT
TAAAGCGGGATGAAAAACAA

Downstream 100 bases:

>100_bases
CCTATTGTGACAGAAGCGCCGAAGGACAATCCGTCTTCCGGCGCTTTATCATTTTCTCCCCCTCTCTCTTTCTTCTCATG
CGCCAAAACGCTTATAATGG

Product: putative shikimate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MNGLTEEYIMKKDLGRINGKTQLIGLFATPIGHSLSPAMHNLAFKKLGLNYAYLAFEVGNEQLEDVVTGMRALNVRGFNV
SMPNKMNILPYLDELADSAKFTGAVNTVVNENGRLIGHSTDGMGYVRNLKEHGIDITGKKMTLVGSGGAATPIAIQSALE
GLGEISIFARNDAFFEKAEENVRIINEEMKGSSCKAKVFPLEDQDALRAEIASSDIFTNGTGVGMKPLEGLSVIEDTSML
RPDLIVTDVVYNPVTSKLLEQAQAAGCNTINGLGMMLWQGAMAFEYWTGREMPVQYIKEQMFE

Sequences:

>Translated_303_residues
MNGLTEEYIMKKDLGRINGKTQLIGLFATPIGHSLSPAMHNLAFKKLGLNYAYLAFEVGNEQLEDVVTGMRALNVRGFNV
SMPNKMNILPYLDELADSAKFTGAVNTVVNENGRLIGHSTDGMGYVRNLKEHGIDITGKKMTLVGSGGAATPIAIQSALE
GLGEISIFARNDAFFEKAEENVRIINEEMKGSSCKAKVFPLEDQDALRAEIASSDIFTNGTGVGMKPLEGLSVIEDTSML
RPDLIVTDVVYNPVTSKLLEQAQAAGCNTINGLGMMLWQGAMAFEYWTGREMPVQYIKEQMFE
>Mature_303_residues
MNGLTEEYIMKKDLGRINGKTQLIGLFATPIGHSLSPAMHNLAFKKLGLNYAYLAFEVGNEQLEDVVTGMRALNVRGFNV
SMPNKMNILPYLDELADSAKFTGAVNTVVNENGRLIGHSTDGMGYVRNLKEHGIDITGKKMTLVGSGGAATPIAIQSALE
GLGEISIFARNDAFFEKAEENVRIINEEMKGSSCKAKVFPLEDQDALRAEIASSDIFTNGTGVGMKPLEGLSVIEDTSML
RPDLIVTDVVYNPVTSKLLEQAQAAGCNTINGLGMMLWQGAMAFEYWTGREMPVQYIKEQMFE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=285, Percent_Identity=51.5789473684211, Blast_Score=304, Evalue=6e-84,
Organism=Escherichia coli, GI1789675, Length=281, Percent_Identity=26.3345195729537, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320332, Length=292, Percent_Identity=30.4794520547945, Blast_Score=89, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 33057; Mature: 33057

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGLTEEYIMKKDLGRINGKTQLIGLFATPIGHSLSPAMHNLAFKKLGLNYAYLAFEVGN
CCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCC
EQLEDVVTGMRALNVRGFNVSMPNKMNILPYLDELADSAKFTGAVNTVVNENGRLIGHST
HHHHHHHHHHHHHEECCEEECCCCCCCHHHHHHHHHHHHHHCHHHHHEECCCCEEEEECC
DGMGYVRNLKEHGIDITGKKMTLVGSGGAATPIAIQSALEGLGEISIFARNDAFFEKAEE
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHC
NVRIINEEMKGSSCKAKVFPLEDQDALRAEIASSDIFTNGTGVGMKPLEGLSVIEDTSML
CCEEEHHHCCCCCCCEEEECCCCCHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHC
RPDLIVTDVVYNPVTSKLLEQAQAAGCNTINGLGMMLWQGAMAFEYWTGREMPVQYIKEQ
CCCEEEEHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHEEECCCCCCCHHHHHHH
MFE
HCC
>Mature Secondary Structure
MNGLTEEYIMKKDLGRINGKTQLIGLFATPIGHSLSPAMHNLAFKKLGLNYAYLAFEVGN
CCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCC
EQLEDVVTGMRALNVRGFNVSMPNKMNILPYLDELADSAKFTGAVNTVVNENGRLIGHST
HHHHHHHHHHHHHEECCEEECCCCCCCHHHHHHHHHHHHHHCHHHHHEECCCCEEEEECC
DGMGYVRNLKEHGIDITGKKMTLVGSGGAATPIAIQSALEGLGEISIFARNDAFFEKAEE
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHC
NVRIINEEMKGSSCKAKVFPLEDQDALRAEIASSDIFTNGTGVGMKPLEGLSVIEDTSML
CCEEEHHHCCCCCCCEEEECCCCCHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHC
RPDLIVTDVVYNPVTSKLLEQAQAAGCNTINGLGMMLWQGAMAFEYWTGREMPVQYIKEQ
CCCEEEEHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHEEECCCCCCCHHHHHHH
MFE
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]