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The map label for this gene is aroE [H]

Identifier: 154685260

GI number: 154685260

Start: 798231

End: 798935

Strand: Reverse

Name: aroE [H]

Synonym: RBAM_008060

Alternate gene names: 154685260

Gene position: 798935-798231 (Counterclockwise)

Preceding gene: 154685261

Following gene: 154685259

Centisome position: 20.39

GC content: 49.36

Gene sequence:

>705_bases
ATGCGCGCCTTAAACGTCAGAGGCTTCAATGTCTCGATGCCGAACAAGATGAACATTCTCCCTTACCTCGATGAACTCGC
GGATTCAGCGAAATTCACCGGCGCGGTGAATACAGTCGTTAATGAAAACGGCAGACTGATCGGACACTCCACTGACGGTA
TGGGATACGTCCGCAACTTAAAAGAACATGGCATCGATATCACAGGCAAAAAAATGACGCTGGTCGGTTCCGGCGGGGCC
GCCACTCCGATAGCGATTCAATCCGCATTGGAAGGCCTCGGAGAAATCTCTATTTTCGCCCGCAATGACGCGTTTTTCGA
AAAAGCGGAAGAAAACGTCCGCATCATCAATGAAGAAATGAAGGGATCTTCTTGCAAAGCGAAAGTCTTCCCGCTCGAAG
ATCAAGATGCGCTGCGTGCTGAAATCGCTTCAAGCGATATTTTCACAAACGGAACGGGTGTCGGCATGAAACCGCTTGAA
GGCTTGAGCGTCATTGAAGATACATCCATGCTCCGTCCTGATTTGATTGTGACAGACGTCGTTTACAACCCCGTTACGTC
GAAATTGCTTGAACAAGCTCAAGCGGCCGGCTGCAACACGATTAACGGCCTCGGCATGATGCTTTGGCAGGGCGCCATGG
CGTTTGAATATTGGACAGGCCGTGAAATGCCGGTTCAGTATATTAAAGAGCAAATGTTTGAATAA

Upstream 100 bases:

>100_bases
AGAAGCGCCGAAGGACAATCCGTCTTCCGGCGCTTTATCATTTTCTCCCCCTCTCTCTTTCTTCTCATGCGCCAAAACGC
TTATAATGGATGTAACGGGA

Downstream 100 bases:

>100_bases
CCTATTGTGACAGAAGCGCCGAAGGACAATCCGTCTTCCGGCGCTTTATCATTTTCTCCCCCTCTCTCTTTCTTCTCATG
CGCCAAAACGCTTATAATGG

Product: putative shikimate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MRALNVRGFNVSMPNKMNILPYLDELADSAKFTGAVNTVVNENGRLIGHSTDGMGYVRNLKEHGIDITGKKMTLVGSGGA
ATPIAIQSALEGLGEISIFARNDAFFEKAEENVRIINEEMKGSSCKAKVFPLEDQDALRAEIASSDIFTNGTGVGMKPLE
GLSVIEDTSMLRPDLIVTDVVYNPVTSKLLEQAQAAGCNTINGLGMMLWQGAMAFEYWTGREMPVQYIKEQMFE

Sequences:

>Translated_234_residues
MRALNVRGFNVSMPNKMNILPYLDELADSAKFTGAVNTVVNENGRLIGHSTDGMGYVRNLKEHGIDITGKKMTLVGSGGA
ATPIAIQSALEGLGEISIFARNDAFFEKAEENVRIINEEMKGSSCKAKVFPLEDQDALRAEIASSDIFTNGTGVGMKPLE
GLSVIEDTSMLRPDLIVTDVVYNPVTSKLLEQAQAAGCNTINGLGMMLWQGAMAFEYWTGREMPVQYIKEQMFE
>Mature_234_residues
MRALNVRGFNVSMPNKMNILPYLDELADSAKFTGAVNTVVNENGRLIGHSTDGMGYVRNLKEHGIDITGKKMTLVGSGGA
ATPIAIQSALEGLGEISIFARNDAFFEKAEENVRIINEEMKGSSCKAKVFPLEDQDALRAEIASSDIFTNGTGVGMKPLE
GLSVIEDTSMLRPDLIVTDVVYNPVTSKLLEQAQAAGCNTINGLGMMLWQGAMAFEYWTGREMPVQYIKEQMFE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=232, Percent_Identity=52.1551724137931, Blast_Score=252, Evalue=1e-68,
Organism=Escherichia coli, GI1789675, Length=230, Percent_Identity=27.8260869565217, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 25493; Mature: 25493

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALNVRGFNVSMPNKMNILPYLDELADSAKFTGAVNTVVNENGRLIGHSTDGMGYVRNL
CCEEEECCEEECCCCCCCHHHHHHHHHHHHHHCHHHHEEECCCCEEEEECCCCHHHHHHH
KEHGIDITGKKMTLVGSGGAATPIAIQSALEGLGEISIFARNDAFFEKAEENVRIINEEM
HHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCEEEHHHC
KGSSCKAKVFPLEDQDALRAEIASSDIFTNGTGVGMKPLEGLSVIEDTSMLRPDLIVTDV
CCCCCCEEEECCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCEEEEHH
VYNPVTSKLLEQAQAAGCNTINGLGMMLWQGAMAFEYWTGREMPVQYIKEQMFE
HHCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MRALNVRGFNVSMPNKMNILPYLDELADSAKFTGAVNTVVNENGRLIGHSTDGMGYVRNL
CCEEEECCEEECCCCCCCHHHHHHHHHHHHHHCHHHHEEECCCCEEEEECCCCHHHHHHH
KEHGIDITGKKMTLVGSGGAATPIAIQSALEGLGEISIFARNDAFFEKAEENVRIINEEM
HHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCEEEHHHC
KGSSCKAKVFPLEDQDALRAEIASSDIFTNGTGVGMKPLEGLSVIEDTSMLRPDLIVTDV
CCCCCCEEEECCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCEEEEHH
VYNPVTSKLLEQAQAAGCNTINGLGMMLWQGAMAFEYWTGREMPVQYIKEQMFE
HHCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]