Click here to switch to the map view.

The map label for this gene is yfkN [H]

Identifier: 154685257

GI number: 154685257

Start: 792014

End: 796306

Strand: Reverse

Name: yfkN [H]

Synonym: RBAM_008030

Alternate gene names: 154685257

Gene position: 796306-792014 (Counterclockwise)

Preceding gene: 154685259

Following gene: 154685256

Centisome position: 20.32

GC content: 49.15

Gene sequence:

>4293_bases
GTGAGAATACAGAAAAGACGATGCAGCGTCAATATGACACTCCGTATTCTGCTGCCACTAGTTATGATACTTAGTCTAAT
CCTCCCAACATCACCCATTAAAGCAGAAGAAAACAAATCCTCCAGTGTGAATCTCAGCATTTTAGCCACAACTGACGTTC
ACGCTAACATGATGGACTACGATTACTACAGCGACAAACCGACAACGGAATTCGGGCTGGCCCGAACGGCTCAGCTTATT
GAGAAGCACAGGCGCGAAAACCCGAATACGCTGCTTGTCGATAACGGAGACCTGATTCAGGGGAATCCCCTCGGAGAATA
CGCCGTAAAATATGAGAAAAATGATATTATTTCAGGCGCAAAGACCCATCCGATCATTGAAGTGATGAACAGTCTGCATT
ATGACGCAGGAACACTCGGCAATCATGAATTTAATTACGGGCTTGAATTTCTGGACGGGACAATCAAAGGCGCTGATTAT
CCGATCGTTAACGCCAATGTGAAAACATTAAGCGGCGAAAACCGTTATACGCCTTATGTCATAAAAGACAAAACCGTCAC
GGATGAAAATGGCGGCAAGCATCAGATAAAAGTCGGCTACATCGGCTTTGTTCCTCCCCAAATCATGACGTGGGATAAGA
AAAATCTCGAAGGCCGCGTTCAGGTCGAGGACATTGTGGAATCCGCAAAGAAAACCGTTCCGAAAATGAAAGCTGAAGGA
GCCGATATCGTCATCGCCCTCGCCCACAGCGGCATCGAAAAAAAAGCGCAGTCTTCCGGAGCGGAAAACGCCGTTTTTGA
CCTGGCAACGAAAGTCAGCGGAATTGATGCGATCGTATCCGGCCATCAGCACGGGCTTTTCCCTGATGCCGAATACAAAG
GCGCTGATCAATTTGACGTCGATAAAGGCACGATTAACGGCATCCCCGTTGTCATGTCAAGCAGCTGGGGCAAATATGCG
GGCGTCATCGACCTCCGGCTTGAAAAGACAGACAGCGCGTGGCATGTGGAAGATGCAAAAGGCAGCATCGAGCCGATTGC
CGGCAATGTGACGTCGGAAAACGAAACCGTCGTCAATACCGTCAAAAAAGCGCACGAAGGCACATTGAAATACATCAGAG
AACCCGTCGGCCAGACAAAAGCCGATATCAACAGTTTCTTCGCCCAAGTCAAAGATGATCCGTCCATTCAAATCGTAACG
GATGCGCAAAAATGGTACGCCGAAAATAAGATGAAGGATACGGAATACAAAGATCTGCCTATCCTCTCGGCGGGCGCCCC
GTTTAAAGCCGGCGGGCGGAACGGCTCAAACTACTATACAAACATTTCCGCTGGCGACCTCGCCATCAAAAATATCGGCG
ATTTGTACCTGTATGACAACACGGTTCAGATCGTCAAGCTGAACGGAAGCGAAGTGAAGGACTGGCTCGAAATGTCCGCA
GGGCAATTTAATCAGATCGATCAGGCAAAAGGCGGCAGCCAAGCGCTTTTAAATGACGCCTACCGCTCATACAATTTTGA
TGTCATTGATGGTGTCACCTATCAGGTCGATGTCACAAAACCTGCGAAATACAACGAAAACGGAACAGTCATTCATCCCG
ATGCAAGCCGGATCGTCAACCTTTCTTATCAAGGAAAGCCCGTCAGCGCCAAGCAGGAATTTCTGATCGTCACAAATAAT
TACCGCGCTTCAGGCGGCGGAGGATTCCCTCACTTAAGCAATGATAAAATCGTATACTCTTCTGCCGATGAGAACAGGCA
GGTCTTAATGGATTACATCATCCAGCAGAAAACGATTAATCCGCAGGCTGATCATAACTGGTCCATCCTTCCGGTCAAAG
GGACAAACCTGACATTTGAATCTTCCTTGGCCGCAAAGCCGTTTGCCGACCGCGCAGATGACGTCGCCTATATCGGTGAA
TCACAAAACGCGGGCTACGGACAGTACAAGCTCCAATTCAAAGATGATGAACCGGGCACAGATCCGCCGAAAGATGACGC
ATGGAAACTCACCGTTATGCATACAAACGACACGCACGCCCACCTTGATAACGCGGCGAGGCGGATGACGAAAATCAAAG
AAATCAGAAGCGAAACCGACCGCAGCATTTTGCTGGATGCGGGAGACGTTTTCTCAGGCGATCTCTATTTCACAAAGTGG
CAGGGGCTGGCTGATTTAAAATTGATGAACAGCATGGGCTACGACGCAATGACCTTCGGAAACCATGAGTTTGATAAAGG
ACCGGGTGCTCTCGCCAGCTTCCTGAGCGGGAACGGTAGCGCGGCTGACCCGTCCGGAAAATACAATTTTCAAGCGCCTG
ACTTTCCGCTCGTCAGCTCAAATGTCGATGTGTCCAAAGAGTCAAAACTCAGACCATTCATGAAAAAAGCAGACACATTT
ACGGCAGGGAAAAAGAAAAAAGCAGGCATCTATCCATACATTCTGCTTGATGTAAACGGAGAAAAAGTCGCCGTATTCGG
CTTAACGACAGAAGATACGTCCGTCACATCAAGCCCGGGAAAAAGCATTGTCTTTCATGATGCCTTCCAATCCGCACAAG
ATACGGTAAAAGAAATACAGAACAAGGAACATGTCAATAAAATTATCGCCCTGACCCATATCGGGCATCAGCGTGATCTC
GATCTTGCCAAAAAGGTAAAAGGCATCGACTTGATCGTCGGCGGACATACGCATACGCTTGTAGATAAAATGGAAGTTGT
CAAAAACGAAGAGCCGACCATCGTCGCCCAGGCAAAAGAATACGGCGAATATTTAGGCCGGGCAGATGTCGCCTTTGACA
AAAACGGCGTCGTCCTGCCGGAACAATCCTCTCTTCAGGCGATTCCGGTGAACGAGCAGACGAAAGAAGACCCGGATCTG
AAAAAAGAGCTTGATCCGTTTAAAAAAGAGCTCGTCTCAGTCAAAAATGAAAAAGTCGGCTCAACGAAGGTCGCACTTGA
CGGCCAGCGCGAGCATGTCCGCTCCAAAGAAACCAATCTCGGAAACTTCATCGCGGACGGCATGCTGCAAAAAGCGAAGG
AAGCGGCCGGCGCCCAAATCGCGATCACAAACGGGGGCGGCATCCGCGCGGGCATTGATAAAGGAGAAATCACACTCGGC
GATGTGCTGAATGTGATGCCGTTCGGCAACACGCTTTACGTCGCGGATTTAACCGGAAAACAGATCAAACAAGCCCTGGA
ACAAGGGTTAAGCGGAATTGAGGCTCAAGGCGGCGCCTTCCCTCAAGTTGCCGGTTTAACATACACGTTTACACTGAATA
AAAAGCCGGGACACCGCGTTCTTCAAGCTGCGGCCGTACAGGATGACGGCAGCGTAAAGCCGATTTCTGATAAGAAGACA
TACAGAGTCGCCACCAGTAACTTTGTCGGTGAAGGCGGAGACGGATATTCCGTCTTTAACGAAGCGTCCCATAAAGAAGA
CCTTGGCTTTGTCGACTATGAGGTCTTCACCGAGCAGCTTGAAAAAGCGGGAAAAGCGGTGGAACCGAAAGTTGACGGCC
GCGCGCAGGAAGTGTACCTGCCGACGAAACAAAAAAACGGTTCGTGGACGCTTGAAGATGACAGCGCATTTGCCGCCTAT
GCCAAAAACGCCAACACGCCGATCGTGTATTACGATAAGAATGACGGCACCAAAAAGCCGATTGATCTCAGCGTGACCAA
AAAACAAATCGGCCTGTTAAAGGACAGAACATCGGATTCTTCCCTTACGATCCTGCATGACAAGTTCAGCATGAAAATGC
CGATGGCAAACGCTGCTTCAGCTGATACACGATTCGGCGTGACGCCGAAAGGAAAAGTAAGCGGGGCGCTTTCAAATGTA
TACGACTTTACAATGAAGCAGAAAAACAAAGACATCAAAACATTCAAAGCGCCGGTAAAGCTCACCCTGCGCATTGAGAA
TACGAAAAAGGCGAAACAGCCGGGCATTTACCATGTAGACCGGAAAAAGAACGTCTATACAAAAACAGACAACGGTTCGG
TTTCACACGATCTCGTCACGGGCTATACAAATCATTTCAGTGAATACACCATATTAAACGCAAACACGAAGAGCGCGCCG
CAACCAAGCGGAGACCAAGGCTCCGGAAAGCAGCCAAGCGGACAAAAACCGTCATCCGGCCCTGCACAGGACGGGGTATC
GCCGGGCGGCCTGCTTCCTGATACGGCCACAACGATGTATTCCATCCTTCTTGCCGGGTTACTCATCAGCGCGCTCGGAA
CGGCACTGTATCTGCATCAAAGAAGAAAAGCAAAAAAAGTGAACGAAGCATAA

Upstream 100 bases:

>100_bases
TCATCTTTTTACAAGAATCATCATGAAATCTATATGAACTTTCACAAAATATTCTTACAATGGTACTGCATGACAAAATT
TGTTGAAAGGTGGAGAACAG

Downstream 100 bases:

>100_bases
AAAGACCGCTTTTATCGGGCGGTTCATCCAAAAGCTCTCCTGATCTGATTTCAGGGGAGCTTTTTCTCTCGGTCCCCCTC
TGAGTCGACAGCCGTACGGC

Product: bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein

Products: NA

Alternate protein names: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase; 5'-nucleotidase [H]

Number of amino acids: Translated: 1430; Mature: 1430

Protein sequence:

>1430_residues
MRIQKRRCSVNMTLRILLPLVMILSLILPTSPIKAEENKSSSVNLSILATTDVHANMMDYDYYSDKPTTEFGLARTAQLI
EKHRRENPNTLLVDNGDLIQGNPLGEYAVKYEKNDIISGAKTHPIIEVMNSLHYDAGTLGNHEFNYGLEFLDGTIKGADY
PIVNANVKTLSGENRYTPYVIKDKTVTDENGGKHQIKVGYIGFVPPQIMTWDKKNLEGRVQVEDIVESAKKTVPKMKAEG
ADIVIALAHSGIEKKAQSSGAENAVFDLATKVSGIDAIVSGHQHGLFPDAEYKGADQFDVDKGTINGIPVVMSSSWGKYA
GVIDLRLEKTDSAWHVEDAKGSIEPIAGNVTSENETVVNTVKKAHEGTLKYIREPVGQTKADINSFFAQVKDDPSIQIVT
DAQKWYAENKMKDTEYKDLPILSAGAPFKAGGRNGSNYYTNISAGDLAIKNIGDLYLYDNTVQIVKLNGSEVKDWLEMSA
GQFNQIDQAKGGSQALLNDAYRSYNFDVIDGVTYQVDVTKPAKYNENGTVIHPDASRIVNLSYQGKPVSAKQEFLIVTNN
YRASGGGGFPHLSNDKIVYSSADENRQVLMDYIIQQKTINPQADHNWSILPVKGTNLTFESSLAAKPFADRADDVAYIGE
SQNAGYGQYKLQFKDDEPGTDPPKDDAWKLTVMHTNDTHAHLDNAARRMTKIKEIRSETDRSILLDAGDVFSGDLYFTKW
QGLADLKLMNSMGYDAMTFGNHEFDKGPGALASFLSGNGSAADPSGKYNFQAPDFPLVSSNVDVSKESKLRPFMKKADTF
TAGKKKKAGIYPYILLDVNGEKVAVFGLTTEDTSVTSSPGKSIVFHDAFQSAQDTVKEIQNKEHVNKIIALTHIGHQRDL
DLAKKVKGIDLIVGGHTHTLVDKMEVVKNEEPTIVAQAKEYGEYLGRADVAFDKNGVVLPEQSSLQAIPVNEQTKEDPDL
KKELDPFKKELVSVKNEKVGSTKVALDGQREHVRSKETNLGNFIADGMLQKAKEAAGAQIAITNGGGIRAGIDKGEITLG
DVLNVMPFGNTLYVADLTGKQIKQALEQGLSGIEAQGGAFPQVAGLTYTFTLNKKPGHRVLQAAAVQDDGSVKPISDKKT
YRVATSNFVGEGGDGYSVFNEASHKEDLGFVDYEVFTEQLEKAGKAVEPKVDGRAQEVYLPTKQKNGSWTLEDDSAFAAY
AKNANTPIVYYDKNDGTKKPIDLSVTKKQIGLLKDRTSDSSLTILHDKFSMKMPMANAASADTRFGVTPKGKVSGALSNV
YDFTMKQKNKDIKTFKAPVKLTLRIENTKKAKQPGIYHVDRKKNVYTKTDNGSVSHDLVTGYTNHFSEYTILNANTKSAP
QPSGDQGSGKQPSGQKPSSGPAQDGVSPGGLLPDTATTMYSILLAGLLISALGTALYLHQRRKAKKVNEA

Sequences:

>Translated_1430_residues
MRIQKRRCSVNMTLRILLPLVMILSLILPTSPIKAEENKSSSVNLSILATTDVHANMMDYDYYSDKPTTEFGLARTAQLI
EKHRRENPNTLLVDNGDLIQGNPLGEYAVKYEKNDIISGAKTHPIIEVMNSLHYDAGTLGNHEFNYGLEFLDGTIKGADY
PIVNANVKTLSGENRYTPYVIKDKTVTDENGGKHQIKVGYIGFVPPQIMTWDKKNLEGRVQVEDIVESAKKTVPKMKAEG
ADIVIALAHSGIEKKAQSSGAENAVFDLATKVSGIDAIVSGHQHGLFPDAEYKGADQFDVDKGTINGIPVVMSSSWGKYA
GVIDLRLEKTDSAWHVEDAKGSIEPIAGNVTSENETVVNTVKKAHEGTLKYIREPVGQTKADINSFFAQVKDDPSIQIVT
DAQKWYAENKMKDTEYKDLPILSAGAPFKAGGRNGSNYYTNISAGDLAIKNIGDLYLYDNTVQIVKLNGSEVKDWLEMSA
GQFNQIDQAKGGSQALLNDAYRSYNFDVIDGVTYQVDVTKPAKYNENGTVIHPDASRIVNLSYQGKPVSAKQEFLIVTNN
YRASGGGGFPHLSNDKIVYSSADENRQVLMDYIIQQKTINPQADHNWSILPVKGTNLTFESSLAAKPFADRADDVAYIGE
SQNAGYGQYKLQFKDDEPGTDPPKDDAWKLTVMHTNDTHAHLDNAARRMTKIKEIRSETDRSILLDAGDVFSGDLYFTKW
QGLADLKLMNSMGYDAMTFGNHEFDKGPGALASFLSGNGSAADPSGKYNFQAPDFPLVSSNVDVSKESKLRPFMKKADTF
TAGKKKKAGIYPYILLDVNGEKVAVFGLTTEDTSVTSSPGKSIVFHDAFQSAQDTVKEIQNKEHVNKIIALTHIGHQRDL
DLAKKVKGIDLIVGGHTHTLVDKMEVVKNEEPTIVAQAKEYGEYLGRADVAFDKNGVVLPEQSSLQAIPVNEQTKEDPDL
KKELDPFKKELVSVKNEKVGSTKVALDGQREHVRSKETNLGNFIADGMLQKAKEAAGAQIAITNGGGIRAGIDKGEITLG
DVLNVMPFGNTLYVADLTGKQIKQALEQGLSGIEAQGGAFPQVAGLTYTFTLNKKPGHRVLQAAAVQDDGSVKPISDKKT
YRVATSNFVGEGGDGYSVFNEASHKEDLGFVDYEVFTEQLEKAGKAVEPKVDGRAQEVYLPTKQKNGSWTLEDDSAFAAY
AKNANTPIVYYDKNDGTKKPIDLSVTKKQIGLLKDRTSDSSLTILHDKFSMKMPMANAASADTRFGVTPKGKVSGALSNV
YDFTMKQKNKDIKTFKAPVKLTLRIENTKKAKQPGIYHVDRKKNVYTKTDNGSVSHDLVTGYTNHFSEYTILNANTKSAP
QPSGDQGSGKQPSGQKPSSGPAQDGVSPGGLLPDTATTMYSILLAGLLISALGTALYLHQRRKAKKVNEA
>Mature_1430_residues
MRIQKRRCSVNMTLRILLPLVMILSLILPTSPIKAEENKSSSVNLSILATTDVHANMMDYDYYSDKPTTEFGLARTAQLI
EKHRRENPNTLLVDNGDLIQGNPLGEYAVKYEKNDIISGAKTHPIIEVMNSLHYDAGTLGNHEFNYGLEFLDGTIKGADY
PIVNANVKTLSGENRYTPYVIKDKTVTDENGGKHQIKVGYIGFVPPQIMTWDKKNLEGRVQVEDIVESAKKTVPKMKAEG
ADIVIALAHSGIEKKAQSSGAENAVFDLATKVSGIDAIVSGHQHGLFPDAEYKGADQFDVDKGTINGIPVVMSSSWGKYA
GVIDLRLEKTDSAWHVEDAKGSIEPIAGNVTSENETVVNTVKKAHEGTLKYIREPVGQTKADINSFFAQVKDDPSIQIVT
DAQKWYAENKMKDTEYKDLPILSAGAPFKAGGRNGSNYYTNISAGDLAIKNIGDLYLYDNTVQIVKLNGSEVKDWLEMSA
GQFNQIDQAKGGSQALLNDAYRSYNFDVIDGVTYQVDVTKPAKYNENGTVIHPDASRIVNLSYQGKPVSAKQEFLIVTNN
YRASGGGGFPHLSNDKIVYSSADENRQVLMDYIIQQKTINPQADHNWSILPVKGTNLTFESSLAAKPFADRADDVAYIGE
SQNAGYGQYKLQFKDDEPGTDPPKDDAWKLTVMHTNDTHAHLDNAARRMTKIKEIRSETDRSILLDAGDVFSGDLYFTKW
QGLADLKLMNSMGYDAMTFGNHEFDKGPGALASFLSGNGSAADPSGKYNFQAPDFPLVSSNVDVSKESKLRPFMKKADTF
TAGKKKKAGIYPYILLDVNGEKVAVFGLTTEDTSVTSSPGKSIVFHDAFQSAQDTVKEIQNKEHVNKIIALTHIGHQRDL
DLAKKVKGIDLIVGGHTHTLVDKMEVVKNEEPTIVAQAKEYGEYLGRADVAFDKNGVVLPEQSSLQAIPVNEQTKEDPDL
KKELDPFKKELVSVKNEKVGSTKVALDGQREHVRSKETNLGNFIADGMLQKAKEAAGAQIAITNGGGIRAGIDKGEITLG
DVLNVMPFGNTLYVADLTGKQIKQALEQGLSGIEAQGGAFPQVAGLTYTFTLNKKPGHRVLQAAAVQDDGSVKPISDKKT
YRVATSNFVGEGGDGYSVFNEASHKEDLGFVDYEVFTEQLEKAGKAVEPKVDGRAQEVYLPTKQKNGSWTLEDDSAFAAY
AKNANTPIVYYDKNDGTKKPIDLSVTKKQIGLLKDRTSDSSLTILHDKFSMKMPMANAASADTRFGVTPKGKVSGALSNV
YDFTMKQKNKDIKTFKAPVKLTLRIENTKKAKQPGIYHVDRKKNVYTKTDNGSVSHDLVTGYTNHFSEYTILNANTKSAP
QPSGDQGSGKQPSGQKPSSGPAQDGVSPGGLLPDTATTMYSILLAGLLISALGTALYLHQRRKAKKVNEA

Specific function: Catalyzes the release of inorganic phosphate from 2',3'- cyclic nucleotides through consecutive 2',3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phospha

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=582, Percent_Identity=31.9587628865979, Blast_Score=252, Evalue=2e-66,
Organism=Escherichia coli, GI1790658, Length=617, Percent_Identity=45.3808752025932, Blast_Score=547, Evalue=1e-156,
Organism=Escherichia coli, GI1786687, Length=564, Percent_Identity=29.0780141843972, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI19922446, Length=547, Percent_Identity=30.8957952468007, Blast_Score=226, Evalue=8e-59,
Organism=Drosophila melanogaster, GI24654424, Length=547, Percent_Identity=30.8957952468007, Blast_Score=226, Evalue=8e-59,
Organism=Drosophila melanogaster, GI19922444, Length=553, Percent_Identity=28.0289330922242, Blast_Score=203, Evalue=6e-52,
Organism=Drosophila melanogaster, GI28573524, Length=560, Percent_Identity=26.7857142857143, Blast_Score=194, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24652512, Length=491, Percent_Identity=28.7169042769857, Blast_Score=182, Evalue=2e-45,
Organism=Drosophila melanogaster, GI19921980, Length=491, Percent_Identity=28.7169042769857, Blast_Score=182, Evalue=2e-45,
Organism=Drosophila melanogaster, GI161076508, Length=491, Percent_Identity=28.7169042769857, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24641187, Length=532, Percent_Identity=25.9398496240602, Blast_Score=172, Evalue=2e-42,
Organism=Drosophila melanogaster, GI221329836, Length=564, Percent_Identity=25.531914893617, Blast_Score=163, Evalue=8e-40,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR019931
- InterPro:   IPR004843
- InterPro:   IPR001899 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.6; =3.1.4.16; =3.1.3.5 [H]

Molecular weight: Translated: 156146; Mature: 156146

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00785 5_NUCLEOTIDASE_1 ; PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIQKRRCSVNMTLRILLPLVMILSLILPTSPIKAEENKSSSVNLSILATTDVHANMMDY
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEC
DYYSDKPTTEFGLARTAQLIEKHRRENPNTLLVDNGDLIQGNPLGEYAVKYEKNDIISGA
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCCCCCCEEEECCCCCCCCC
KTHPIIEVMNSLHYDAGTLGNHEFNYGLEFLDGTIKGADYPIVNANVKTLSGENRYTPYV
CCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCEECCCCCEEEECCEEEECCCCCCCCEE
IKDKTVTDENGGKHQIKVGYIGFVPPQIMTWDKKNLEGRVQVEDIVESAKKTVPKMKAEG
EECCEECCCCCCCEEEEEEEEECCCCCCEECCCCCCCCEEEHHHHHHHHHHHCCHHHCCC
ADIVIALAHSGIEKKAQSSGAENAVFDLATKVSGIDAIVSGHQHGLFPDAEYKGADQFDV
CCEEEEEECCCHHHHHHHCCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCC
DKGTINGIPVVMSSSWGKYAGVIDLRLEKTDSAWHVEDAKGSIEPIAGNVTSENETVVNT
CCCCCCCEEEEEECCCCCEEEEEEEEEECCCCCEEEECCCCCCCEEECCCCCCCHHHHHH
VKKAHEGTLKYIREPVGQTKADINSFFAQVKDDPSIQIVTDAQKWYAENKMKDTEYKDLP
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCCCCCCE
ILSAGAPFKAGGRNGSNYYTNISAGDLAIKNIGDLYLYDNTVQIVKLNGSEVKDWLEMSA
EEECCCCCCCCCCCCCCEEEECCCCCEEECCCCCEEEECCEEEEEEECCHHHHHHHHHCC
GQFNQIDQAKGGSQALLNDAYRSYNFDVIDGVTYQVDVTKPAKYNENGTVIHPDASRIVN
CCCCCHHHCCCCCHHHHHHHHHHCCCEEECCEEEEEEECCCCCCCCCCCEECCCHHHEEE
LSYQGKPVSAKQEFLIVTNNYRASGGGGFPHLSNDKIVYSSADENRQVLMDYIIQQKTIN
EEECCCCCCCCCCEEEEECCEECCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCC
PQADHNWSILPVKGTNLTFESSLAAKPFADRADDVAYIGESQNAGYGQYKLQFKDDEPGT
CCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCC
DPPKDDAWKLTVMHTNDTHAHLDNAARRMTKIKEIRSETDRSILLDAGDVFSGDLYFTKW
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCEEEEEC
QGLADLKLMNSMGYDAMTFGNHEFDKGPGALASFLSGNGSAADPSGKYNFQAPDFPLVSS
CCCHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECC
NVDVSKESKLRPFMKKADTFTAGKKKKAGIYPYILLDVNGEKVAVFGLTTEDTSVTSSPG
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCCCCC
KSIVFHDAFQSAQDTVKEIQNKEHVNKIIALTHIGHQRDLDLAKKVKGIDLIVGGHTHTL
CEEEEEHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHCCCEEEEECCCHHHH
VDKMEVVKNEEPTIVAQAKEYGEYLGRADVAFDKNGVVLPEQSSLQAIPVNEQTKEDPDL
HHHHHHHCCCCCEEEEEHHHHHHHHCCCCEEECCCCEECCCCCCCEEECCCCCCCCCCCH
KKELDPFKKELVSVKNEKVGSTKVALDGQREHVRSKETNLGNFIADGMLQKAKEAAGAQI
HHHHCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEE
AITNGGGIRAGIDKGEITLGDVLNVMPFGNTLYVADLTGKQIKQALEQGLSGIEAQGGAF
EEECCCCEEECCCCCCEEHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCC
PQVAGLTYTFTLNKKPGHRVLQAAAVQDDGSVKPISDKKTYRVATSNFVGEGGDGYSVFN
CEECCEEEEEEECCCCCHHHHHHHEECCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHC
EASHKEDLGFVDYEVFTEQLEKAGKAVEPKVDGRAQEVYLPTKQKNGSWTLEDDSAFAAY
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCEEEE
AKNANTPIVYYDKNDGTKKPIDLSVTKKQIGLLKDRTSDSSLTILHDKFSMKMPMANAAS
CCCCCCCEEEEECCCCCCCCEEEEECHHHHHHHHCCCCCCCEEEEEECCEECCCCCCCCC
ADTRFGVTPKGKVSGALSNVYDFTMKQKNKDIKTFKAPVKLTLRIENTKKAKQPGIYHVD
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEEECCCCCCCCCCCEEEC
RKKNVYTKTDNGSVSHDLVTGYTNHFSEYTILNANTKSAPQPSGDQGSGKQPSGQKPSSG
CCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
PAQDGVSPGGLLPDTATTMYSILLAGLLISALGTALYLHQRRKAKKVNEA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRIQKRRCSVNMTLRILLPLVMILSLILPTSPIKAEENKSSSVNLSILATTDVHANMMDY
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEC
DYYSDKPTTEFGLARTAQLIEKHRRENPNTLLVDNGDLIQGNPLGEYAVKYEKNDIISGA
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCCCCCCEEEECCCCCCCCC
KTHPIIEVMNSLHYDAGTLGNHEFNYGLEFLDGTIKGADYPIVNANVKTLSGENRYTPYV
CCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCEECCCCCEEEECCEEEECCCCCCCCEE
IKDKTVTDENGGKHQIKVGYIGFVPPQIMTWDKKNLEGRVQVEDIVESAKKTVPKMKAEG
EECCEECCCCCCCEEEEEEEEECCCCCCEECCCCCCCCEEEHHHHHHHHHHHCCHHHCCC
ADIVIALAHSGIEKKAQSSGAENAVFDLATKVSGIDAIVSGHQHGLFPDAEYKGADQFDV
CCEEEEEECCCHHHHHHHCCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCC
DKGTINGIPVVMSSSWGKYAGVIDLRLEKTDSAWHVEDAKGSIEPIAGNVTSENETVVNT
CCCCCCCEEEEEECCCCCEEEEEEEEEECCCCCEEEECCCCCCCEEECCCCCCCHHHHHH
VKKAHEGTLKYIREPVGQTKADINSFFAQVKDDPSIQIVTDAQKWYAENKMKDTEYKDLP
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCCCCCCE
ILSAGAPFKAGGRNGSNYYTNISAGDLAIKNIGDLYLYDNTVQIVKLNGSEVKDWLEMSA
EEECCCCCCCCCCCCCCEEEECCCCCEEECCCCCEEEECCEEEEEEECCHHHHHHHHHCC
GQFNQIDQAKGGSQALLNDAYRSYNFDVIDGVTYQVDVTKPAKYNENGTVIHPDASRIVN
CCCCCHHHCCCCCHHHHHHHHHHCCCEEECCEEEEEEECCCCCCCCCCCEECCCHHHEEE
LSYQGKPVSAKQEFLIVTNNYRASGGGGFPHLSNDKIVYSSADENRQVLMDYIIQQKTIN
EEECCCCCCCCCCEEEEECCEECCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCC
PQADHNWSILPVKGTNLTFESSLAAKPFADRADDVAYIGESQNAGYGQYKLQFKDDEPGT
CCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCC
DPPKDDAWKLTVMHTNDTHAHLDNAARRMTKIKEIRSETDRSILLDAGDVFSGDLYFTKW
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCEEEEEC
QGLADLKLMNSMGYDAMTFGNHEFDKGPGALASFLSGNGSAADPSGKYNFQAPDFPLVSS
CCCHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECC
NVDVSKESKLRPFMKKADTFTAGKKKKAGIYPYILLDVNGEKVAVFGLTTEDTSVTSSPG
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCCCCC
KSIVFHDAFQSAQDTVKEIQNKEHVNKIIALTHIGHQRDLDLAKKVKGIDLIVGGHTHTL
CEEEEEHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHCCCEEEEECCCHHHH
VDKMEVVKNEEPTIVAQAKEYGEYLGRADVAFDKNGVVLPEQSSLQAIPVNEQTKEDPDL
HHHHHHHCCCCCEEEEEHHHHHHHHCCCCEEECCCCEECCCCCCCEEECCCCCCCCCCCH
KKELDPFKKELVSVKNEKVGSTKVALDGQREHVRSKETNLGNFIADGMLQKAKEAAGAQI
HHHHCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEE
AITNGGGIRAGIDKGEITLGDVLNVMPFGNTLYVADLTGKQIKQALEQGLSGIEAQGGAF
EEECCCCEEECCCCCCEEHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCC
PQVAGLTYTFTLNKKPGHRVLQAAAVQDDGSVKPISDKKTYRVATSNFVGEGGDGYSVFN
CEECCEEEEEEECCCCCHHHHHHHEECCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHC
EASHKEDLGFVDYEVFTEQLEKAGKAVEPKVDGRAQEVYLPTKQKNGSWTLEDDSAFAAY
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCEEEE
AKNANTPIVYYDKNDGTKKPIDLSVTKKQIGLLKDRTSDSSLTILHDKFSMKMPMANAAS
CCCCCCCEEEEECCCCCCCCEEEEECHHHHHHHHCCCCCCCEEEEEECCEECCCCCCCCC
ADTRFGVTPKGKVSGALSNVYDFTMKQKNKDIKTFKAPVKLTLRIENTKKAKQPGIYHVD
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEEECCCCCCCCCCCEEEC
RKKNVYTKTDNGSVSHDLVTGYTNHFSEYTILNANTKSAPQPSGDQGSGKQPSGQKPSSG
CCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
PAQDGVSPGGLLPDTATTMYSILLAGLLISALGTALYLHQRRKAKKVNEA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]