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The map label for this gene is yflE [H]

Identifier: 154685246

GI number: 154685246

Start: 781354

End: 783291

Strand: Reverse

Name: yflE [H]

Synonym: RBAM_007920

Alternate gene names: 154685246

Gene position: 783291-781354 (Counterclockwise)

Preceding gene: 154685248

Following gene: 154685243

Centisome position: 19.99

GC content: 43.81

Gene sequence:

>1938_bases
ATGAAAACATTTATAAAAGAAAGAGGACTTGCCTTCTTCTTGATAGCGGTCGTGTTATTGTGGGTGAAAACATATGTCGC
TTATATTTTAAACTTTAACCTCGGCATAGACAACACGATCCAGAAAATATTGCTTTTTGTGAATCCGCTGAGCTCCAGCT
TGTTCTTTCTTGGATTTGGGCTTCTTTTCAAGAAAAAATTACAGCAGACAGCCATTATTGTGATTCATTTTTTATTGTCT
TTTTTGCTTTTTGCAAACATCGTCTATTATAGATTCTTTAATGATTTCATTACCATCCCGGTCATGATGCAGGCAAAGAC
AAATGGCGGCCAGCTCGGAGACAGCGCGTTCTCGTTAATGAGATGGACAGACGCCTTCTACTTCCTGGATACCGTCATTT
TGATTATTTTGGCCCTTAAGATGAGAAAACCGGCTGAAAAACCGGCGAAGAAATCATTCAGAATCGTTTTGGCTTCCGCC
GTGCTTATGTTCCTGATCAACCTCGCCGTCGCGGAATCCGACCGTCCTGAGCTTTTGACACGCTCATTTGACCGAAACTA
TCTGGTGAAATACTTGGGCACGTACAACTTTACGATTTACGATGCCGTGCAGAATGTGAAATCAAACAGCCAGCGCGCGC
TTGCCGATTCAAGCGATGTAACGGATGTGGAAAACTATATGAAGGCCAACTATGACGTGCCGAATAACGTCTACTTCGGA
AAAGCCGAAGGAAAAAACGTCATCTACGTCTCATTAGAGTCTCTGCAATCCTTTATCATTGACTATAAAATTAACGGCAA
GGAAGTGACGCCGTTTTTAAACAAACTGGCGCACGATAATCAAACATTCTACTTTGATAACTTTTTCCACCAAACGGGAC
AAGGTAAAACATCTGATGCGGAATTTATGATGGAGAACTCTCTGTACCCGCTTTCGCAAGGTTCGGTTTTCGTCAATAAA
GCGCAAAACACGCTGCAGTCCGTTCCTGCCATCTTAAAAGGCAAAAAGTACACGTCTGCCGCTTTCCACGGAAATACGCA
GACTTTCTGGAACCGTAACGAAATGTACAAAGCGGAAGGCATCGATAAGTTTTTCGATTCCGCTTATTATGACATGAGCG
AAGAAAACACGAAAAACTACGGCATGAAAGATAAACCGTATTTCAAAGAATCCATGCCGCTCTTAAAGAGCCTGCCGCAG
CCGTTCTATACGAAGTTCATTACGCTGTCCAACCACTTCCCGTTCGGAATGGATAAAGAAGACACGGACTTCCCGGCGGG
AGACTTTGGCGATTCAGTCGTTAATAATTACTTCCAGTCCGCGAACTATCTGGATGAATCAATTGAACAGTTCTTTCATG
ACCTGAAAAAAGACGGCCTGTACGATAAGTCGATTATCGTGATGTACGGAGACCACTACGGCATCTCCGAAAACCATAAT
AAAGCGATGGCGAAAGTGCTCGGCAAAGATGAGATCACTGAATACGACAATGCCCAGCTTCAGCGGGTGCCGCTCTTTAT
CCACGCTCCCGGCGTGAAAGGCGGCCGTAATCACAAATTTGCCGGTGAAGTCGATGTCGCGCCGACCGTTCTTCATCTGC
TCGGCGTCGATACGAAAGATTATCTCATGTCAGGTTCAGATATCTTATCGAAAGAGCACAGAGAAGTCATTCCGTTCCGT
AACGGAGACTTCATCTCACCGAACTATACGAAAGTGTCCGGCAAGTATTACGATACGAAAACCGGAAGACTTTTAGATGA
TTCAGAAGTCGACAAAAAAGAAGACTCTCTCGTCAAGACTGAGCTTGAAATGTCTGATAAGATCATCAACGGCGATCTGC
TTCGTTTCTATCAGCCGAAAGGCTTTAAGAAAGTGGATCCTTCACAATTCGATTATACGAAGCGTGAAGATTCCTCAGCA
GATGATCAAAAAGAATAA

Upstream 100 bases:

>100_bases
CTTTTCCACCTTTTCTATTTGCTGGTTTCATGGTATATTGATTACGTTCGTTTTTTCTATCGTTCCGTGTAAACCGTGAT
CGGAAAAAAGGAGTGTAACA

Downstream 100 bases:

>100_bases
ACAAAAGCCAGATCATATCAATGATCTGGCTTTTTTATGTTCAGCTCCCGGCGGCGGCCATAGAGCGCTTTTGCAGGCTG
TCGGAAAGAACTGAATAAGC

Product: YflE

Products: NA

Alternate protein names: LTA synthase 2; Polyglycerol phosphate synthase 2 [H]

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MKTFIKERGLAFFLIAVVLLWVKTYVAYILNFNLGIDNTIQKILLFVNPLSSSLFFLGFGLLFKKKLQQTAIIVIHFLLS
FLLFANIVYYRFFNDFITIPVMMQAKTNGGQLGDSAFSLMRWTDAFYFLDTVILIILALKMRKPAEKPAKKSFRIVLASA
VLMFLINLAVAESDRPELLTRSFDRNYLVKYLGTYNFTIYDAVQNVKSNSQRALADSSDVTDVENYMKANYDVPNNVYFG
KAEGKNVIYVSLESLQSFIIDYKINGKEVTPFLNKLAHDNQTFYFDNFFHQTGQGKTSDAEFMMENSLYPLSQGSVFVNK
AQNTLQSVPAILKGKKYTSAAFHGNTQTFWNRNEMYKAEGIDKFFDSAYYDMSEENTKNYGMKDKPYFKESMPLLKSLPQ
PFYTKFITLSNHFPFGMDKEDTDFPAGDFGDSVVNNYFQSANYLDESIEQFFHDLKKDGLYDKSIIVMYGDHYGISENHN
KAMAKVLGKDEITEYDNAQLQRVPLFIHAPGVKGGRNHKFAGEVDVAPTVLHLLGVDTKDYLMSGSDILSKEHREVIPFR
NGDFISPNYTKVSGKYYDTKTGRLLDDSEVDKKEDSLVKTELEMSDKIINGDLLRFYQPKGFKKVDPSQFDYTKREDSSA
DDQKE

Sequences:

>Translated_645_residues
MKTFIKERGLAFFLIAVVLLWVKTYVAYILNFNLGIDNTIQKILLFVNPLSSSLFFLGFGLLFKKKLQQTAIIVIHFLLS
FLLFANIVYYRFFNDFITIPVMMQAKTNGGQLGDSAFSLMRWTDAFYFLDTVILIILALKMRKPAEKPAKKSFRIVLASA
VLMFLINLAVAESDRPELLTRSFDRNYLVKYLGTYNFTIYDAVQNVKSNSQRALADSSDVTDVENYMKANYDVPNNVYFG
KAEGKNVIYVSLESLQSFIIDYKINGKEVTPFLNKLAHDNQTFYFDNFFHQTGQGKTSDAEFMMENSLYPLSQGSVFVNK
AQNTLQSVPAILKGKKYTSAAFHGNTQTFWNRNEMYKAEGIDKFFDSAYYDMSEENTKNYGMKDKPYFKESMPLLKSLPQ
PFYTKFITLSNHFPFGMDKEDTDFPAGDFGDSVVNNYFQSANYLDESIEQFFHDLKKDGLYDKSIIVMYGDHYGISENHN
KAMAKVLGKDEITEYDNAQLQRVPLFIHAPGVKGGRNHKFAGEVDVAPTVLHLLGVDTKDYLMSGSDILSKEHREVIPFR
NGDFISPNYTKVSGKYYDTKTGRLLDDSEVDKKEDSLVKTELEMSDKIINGDLLRFYQPKGFKKVDPSQFDYTKREDSSA
DDQKE
>Mature_645_residues
MKTFIKERGLAFFLIAVVLLWVKTYVAYILNFNLGIDNTIQKILLFVNPLSSSLFFLGFGLLFKKKLQQTAIIVIHFLLS
FLLFANIVYYRFFNDFITIPVMMQAKTNGGQLGDSAFSLMRWTDAFYFLDTVILIILALKMRKPAEKPAKKSFRIVLASA
VLMFLINLAVAESDRPELLTRSFDRNYLVKYLGTYNFTIYDAVQNVKSNSQRALADSSDVTDVENYMKANYDVPNNVYFG
KAEGKNVIYVSLESLQSFIIDYKINGKEVTPFLNKLAHDNQTFYFDNFFHQTGQGKTSDAEFMMENSLYPLSQGSVFVNK
AQNTLQSVPAILKGKKYTSAAFHGNTQTFWNRNEMYKAEGIDKFFDSAYYDMSEENTKNYGMKDKPYFKESMPLLKSLPQ
PFYTKFITLSNHFPFGMDKEDTDFPAGDFGDSVVNNYFQSANYLDESIEQFFHDLKKDGLYDKSIIVMYGDHYGISENHN
KAMAKVLGKDEITEYDNAQLQRVPLFIHAPGVKGGRNHKFAGEVDVAPTVLHLLGVDTKDYLMSGSDILSKEHREVIPFR
NGDFISPNYTKVSGKYYDTKTGRLLDDSEVDKKEDSLVKTELEMSDKIINGDLLRFYQPKGFKKVDPSQFDYTKREDSSA
DDQKE

Specific function: Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate [H]

COG id: COG1368

COG function: function code M; Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

Gene ontology:

Cell location: Processed glycerol phosphate lipoteichoic acid synthase 2:Secreted. Note=The secretion into the extracellular medium is dependent on secA and ffh [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LTA synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012160
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: NA

Molecular weight: Translated: 73876; Mature: 73876

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFIKERGLAFFLIAVVLLWVKTYVAYILNFNLGIDNTIQKILLFVNPLSSSLFFLGFG
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
LLFKKKLQQTAIIVIHFLLSFLLFANIVYYRFFNDFITIPVMMQAKTNGGQLGDSAFSLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCHHHHHHH
RWTDAFYFLDTVILIILALKMRKPAEKPAKKSFRIVLASAVLMFLINLAVAESDRPELLT
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RSFDRNYLVKYLGTYNFTIYDAVQNVKSNSQRALADSSDVTDVENYMKANYDVPNNVYFG
HHCCHHHHHHHHCCCCEEHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHCCCCCCCCEEEE
KAEGKNVIYVSLESLQSFIIDYKINGKEVTPFLNKLAHDNQTFYFDNFFHQTGQGKTSDA
CCCCCEEEEEEHHHHHHHHEEEEECCCCHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCH
EFMMENSLYPLSQGSVFVNKAQNTLQSVPAILKGKKYTSAAFHGNTQTFWNRNEMYKAEG
HHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEECCCCHHCCCCCHHEHHCC
IDKFFDSAYYDMSEENTKNYGMKDKPYFKESMPLLKSLPQPFYTKFITLSNHFPFGMDKE
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCHHHHHCCCHHHHHEEEECCCCCCCCCCC
DTDFPAGDFGDSVVNNYFQSANYLDESIEQFFHDLKKDGLYDKSIIVMYGDHYGISENHN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCH
KAMAKVLGKDEITEYDNAQLQRVPLFIHAPGVKGGRNHKFAGEVDVAPTVLHLLGVDTKD
HHHHHHHCCHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHH
YLMSGSDILSKEHREVIPFRNGDFISPNYTKVSGKYYDTKTGRLLDDSEVDKKEDSLVKT
HHHCCHHHHHHHHHHCCCCCCCCCCCCCCEEECCEEEECCCCCCCCCCCCCCHHHHHHHH
ELEMSDKIINGDLLRFYQPKGFKKVDPSQFDYTKREDSSADDQKE
HHHHHHHHCCCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTFIKERGLAFFLIAVVLLWVKTYVAYILNFNLGIDNTIQKILLFVNPLSSSLFFLGFG
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
LLFKKKLQQTAIIVIHFLLSFLLFANIVYYRFFNDFITIPVMMQAKTNGGQLGDSAFSLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCHHHHHHH
RWTDAFYFLDTVILIILALKMRKPAEKPAKKSFRIVLASAVLMFLINLAVAESDRPELLT
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RSFDRNYLVKYLGTYNFTIYDAVQNVKSNSQRALADSSDVTDVENYMKANYDVPNNVYFG
HHCCHHHHHHHHCCCCEEHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHCCCCCCCCEEEE
KAEGKNVIYVSLESLQSFIIDYKINGKEVTPFLNKLAHDNQTFYFDNFFHQTGQGKTSDA
CCCCCEEEEEEHHHHHHHHEEEEECCCCHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCH
EFMMENSLYPLSQGSVFVNKAQNTLQSVPAILKGKKYTSAAFHGNTQTFWNRNEMYKAEG
HHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEECCCCHHCCCCCHHEHHCC
IDKFFDSAYYDMSEENTKNYGMKDKPYFKESMPLLKSLPQPFYTKFITLSNHFPFGMDKE
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCHHHHHCCCHHHHHEEEECCCCCCCCCCC
DTDFPAGDFGDSVVNNYFQSANYLDESIEQFFHDLKKDGLYDKSIIVMYGDHYGISENHN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCH
KAMAKVLGKDEITEYDNAQLQRVPLFIHAPGVKGGRNHKFAGEVDVAPTVLHLLGVDTKD
HHHHHHHCCHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHH
YLMSGSDILSKEHREVIPFRNGDFISPNYTKVSGKYYDTKTGRLLDDSEVDKKEDSLVKT
HHHCCHHHHHHHHHHCCCCCCCCCCCCCCEEECCEEEECCCCCCCCCCCCCCHHHHHHHH
ELEMSDKIINGDLLRFYQPKGFKKVDPSQFDYTKREDSSADDQKE
HHHHHHHHCCCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 10658653 [H]