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The map label for this gene is glpT [H]

Identifier: 154684730

GI number: 154684730

Start: 233094

End: 234428

Strand: Reverse

Name: glpT [H]

Synonym: RBAM_002610

Alternate gene names: 154684730

Gene position: 234428-233094 (Counterclockwise)

Preceding gene: 154684732

Following gene: 154684729

Centisome position: 5.98

GC content: 48.69

Gene sequence:

>1335_bases
ATGTTTCAATTGTTTAAGCCGGCTCCGCATATTGAGAGATTGGATGATTCAAAGACGGATGCGGCCTATAAACGGCTCAG
GCTGCAAGTATTTTTGGGGATTTTCATCGGGTATGCCGGGTATTATTTGCTTCGCAAAAACTTTGCCTTCGCTATCCCTT
ATTTTCAGGAACAAGGTTTTTCAAAAGGGGAACTTGGCTTGGTGCTTGCGGCCGTATCAATCGCTTACGGCTTCAGTAAA
TTTATTATGGGGATGGTGTCTGACCGCTGCAACCCGAGGTATTTCCTTGCGACGGGTCTGTTTTTGTCAGGTGTCGTAAA
CATTTTATTTGTTTCCATGCCGTGGGTCACGTCAAGCGTGACGATTATGTTTATTTTTATGTTTATTAACGGATGGTTTC
AAGGAATGGGCTGGCCGCCTTGCGGACGGACGATGGCTCATTGGTTTTCCATCAGTGAACGCGGTACGAAAATGTCGATA
TGGAATGTCGCCCATAACATAGGCGGAGGTATTCTCGCCCCGCTCGTGACTCTCGGCATCGCCATGTTTGTTACTTGGAA
AAGCGTGTTTTTCTTTCCGGCGATTATCGCCATCGTCATTTCATTTGTGATTGTTCTTCTCGTACGGGACACGCCGCAAT
CCTGCGGGCTTCCGCCGATTGAAGAATACCGGAATGACTATCCGAAACATGCGTTCAAAGACCAGGAAAAAGAGATGACG
ACCAAAGAAATTCTTTTCAAATACGTGCTGAATAATAAGTTTCTGTGGTATATCGCATTTGCCAATGTGTTTGTTTATTT
TGTGCGGTACGGTGTCGTTGACTGGGCGCCGACTTATTTGACGGAAGCGAAAGGGTTCTCTCCTGAAGATTCCAGATGGT
CTTATTTCCTTTATGAATATGCGGGAATTCCGGGAACGATTTTGTGCGGCTGGATCAGCGACCGGTTTTTCAAAAGCCGC
CGCGCGCCGGCAGGCGTACTGTTCATGGCCGGCGTATTTATCGCTGTATTGGTCTACTGGCTTAACCCTGCCGGTCATCC
GCTCATCGATAATATCGCGCTGATCAGCATCGGCTTCTTAATCTATGGACCTGTCATGCTGATCGGGCTTCAGGCCATTG
ACCTTGCGCCTAAAAAAGCGGCGGGAACGGCAGCCGGCTTAACCGGGTTTTTCGGCTACATCGGAGGCTCTGCTTTCGCC
AACGCCATCATGGGTTATGTCGTAGACCGCTTTGACTGGAACGGCGGCTTTATCATGCTTATCTCCTCATGCGTGCTGTC
CATCGTCTTCTTGGCTATGACGTGGAATACGGGCAAGCGGGCGGAGCATGTGTAA

Upstream 100 bases:

>100_bases
CCCGCCCTTTCACAAGGGTGATTTCTGGTTCTTTTTGTCATTTTCAAGGAAAGGAGTCATACATACATCATGATAGACGT
TCAGCAAAGGGGAGGATATG

Downstream 100 bases:

>100_bases
GAAAACAACATAAAAGATTAATATTTTTGCAGTACAGCATTTACAACGATTTTCTACACTAGAGACAGATATTGATTTTT
AAGGGGGAAGAAAACATGCG

Product: GlpT

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MFQLFKPAPHIERLDDSKTDAAYKRLRLQVFLGIFIGYAGYYLLRKNFAFAIPYFQEQGFSKGELGLVLAAVSIAYGFSK
FIMGMVSDRCNPRYFLATGLFLSGVVNILFVSMPWVTSSVTIMFIFMFINGWFQGMGWPPCGRTMAHWFSISERGTKMSI
WNVAHNIGGGILAPLVTLGIAMFVTWKSVFFFPAIIAIVISFVIVLLVRDTPQSCGLPPIEEYRNDYPKHAFKDQEKEMT
TKEILFKYVLNNKFLWYIAFANVFVYFVRYGVVDWAPTYLTEAKGFSPEDSRWSYFLYEYAGIPGTILCGWISDRFFKSR
RAPAGVLFMAGVFIAVLVYWLNPAGHPLIDNIALISIGFLIYGPVMLIGLQAIDLAPKKAAGTAAGLTGFFGYIGGSAFA
NAIMGYVVDRFDWNGGFIMLISSCVLSIVFLAMTWNTGKRAEHV

Sequences:

>Translated_444_residues
MFQLFKPAPHIERLDDSKTDAAYKRLRLQVFLGIFIGYAGYYLLRKNFAFAIPYFQEQGFSKGELGLVLAAVSIAYGFSK
FIMGMVSDRCNPRYFLATGLFLSGVVNILFVSMPWVTSSVTIMFIFMFINGWFQGMGWPPCGRTMAHWFSISERGTKMSI
WNVAHNIGGGILAPLVTLGIAMFVTWKSVFFFPAIIAIVISFVIVLLVRDTPQSCGLPPIEEYRNDYPKHAFKDQEKEMT
TKEILFKYVLNNKFLWYIAFANVFVYFVRYGVVDWAPTYLTEAKGFSPEDSRWSYFLYEYAGIPGTILCGWISDRFFKSR
RAPAGVLFMAGVFIAVLVYWLNPAGHPLIDNIALISIGFLIYGPVMLIGLQAIDLAPKKAAGTAAGLTGFFGYIGGSAFA
NAIMGYVVDRFDWNGGFIMLISSCVLSIVFLAMTWNTGKRAEHV
>Mature_444_residues
MFQLFKPAPHIERLDDSKTDAAYKRLRLQVFLGIFIGYAGYYLLRKNFAFAIPYFQEQGFSKGELGLVLAAVSIAYGFSK
FIMGMVSDRCNPRYFLATGLFLSGVVNILFVSMPWVTSSVTIMFIFMFINGWFQGMGWPPCGRTMAHWFSISERGTKMSI
WNVAHNIGGGILAPLVTLGIAMFVTWKSVFFFPAIIAIVISFVIVLLVRDTPQSCGLPPIEEYRNDYPKHAFKDQEKEMT
TKEILFKYVLNNKFLWYIAFANVFVYFVRYGVVDWAPTYLTEAKGFSPEDSRWSYFLYEYAGIPGTILCGWISDRFFKSR
RAPAGVLFMAGVFIAVLVYWLNPAGHPLIDNIALISIGFLIYGPVMLIGLQAIDLAPKKAAGTAAGLTGFFGYIGGSAFA
NAIMGYVVDRFDWNGGFIMLISSCVLSIVFLAMTWNTGKRAEHV

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=406, Percent_Identity=29.3103448275862, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI4503847, Length=406, Percent_Identity=29.3103448275862, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI256219483, Length=406, Percent_Identity=29.3103448275862, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI256219543, Length=429, Percent_Identity=28.4382284382284, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI256219564, Length=337, Percent_Identity=27.5964391691395, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI38093649, Length=401, Percent_Identity=27.1820448877805, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI223717983, Length=401, Percent_Identity=27.1820448877805, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI46361976, Length=388, Percent_Identity=24.4845360824742, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI49619231, Length=368, Percent_Identity=23.9130434782609, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1788573, Length=443, Percent_Identity=58.9164785553047, Blast_Score=563, Evalue=1e-161,
Organism=Escherichia coli, GI87082310, Length=429, Percent_Identity=35.4312354312354, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI2367259, Length=417, Percent_Identity=32.3741007194245, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI2367379, Length=394, Percent_Identity=23.3502538071066, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789152, Length=413, Percent_Identity=24.2130750605327, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082320, Length=404, Percent_Identity=23.7623762376238, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789515, Length=452, Percent_Identity=23.4513274336283, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17564202, Length=415, Percent_Identity=25.3012048192771, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17564204, Length=352, Percent_Identity=25.8522727272727, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI133930953, Length=478, Percent_Identity=22.3849372384937, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI133901856, Length=486, Percent_Identity=22.4279835390947, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI133901854, Length=486, Percent_Identity=22.4279835390947, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561094, Length=393, Percent_Identity=22.64631043257, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17542316, Length=463, Percent_Identity=22.4622030237581, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17539138, Length=307, Percent_Identity=24.4299674267101, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24656866, Length=495, Percent_Identity=24.8484848484848, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45550478, Length=495, Percent_Identity=24.8484848484848, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24656861, Length=495, Percent_Identity=24.8484848484848, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49847; Mature: 49847

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQLFKPAPHIERLDDSKTDAAYKRLRLQVFLGIFIGYAGYYLLRKNFAFAIPYFQEQGF
CCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHCCC
SKGELGLVLAAVSIAYGFSKFIMGMVSDRCNPRYFLATGLFLSGVVNILFVSMPWVTSSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
TIMFIFMFINGWFQGMGWPPCGRTMAHWFSISERGTKMSIWNVAHNIGGGILAPLVTLGI
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHCCCHHHHHHHHHHH
AMFVTWKSVFFFPAIIAIVISFVIVLLVRDTPQSCGLPPIEEYRNDYPKHAFKDQEKEMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCHHHCCHHHHHH
TKEILFKYVLNNKFLWYIAFANVFVYFVRYGVVDWAPTYLTEAKGFSPEDSRWSYFLYEY
HHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCEEEEEEE
AGIPGTILCGWISDRFFKSRRAPAGVLFMAGVFIAVLVYWLNPAGHPLIDNIALISIGFL
CCCCHHEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
IYGPVMLIGLQAIDLAPKKAAGTAAGLTGFFGYIGGSAFANAIMGYVVDRFDWNGGFIML
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHH
ISSCVLSIVFLAMTWNTGKRAEHV
HHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFQLFKPAPHIERLDDSKTDAAYKRLRLQVFLGIFIGYAGYYLLRKNFAFAIPYFQEQGF
CCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHCCC
SKGELGLVLAAVSIAYGFSKFIMGMVSDRCNPRYFLATGLFLSGVVNILFVSMPWVTSSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
TIMFIFMFINGWFQGMGWPPCGRTMAHWFSISERGTKMSIWNVAHNIGGGILAPLVTLGI
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHCCCHHHHHHHHHHH
AMFVTWKSVFFFPAIIAIVISFVIVLLVRDTPQSCGLPPIEEYRNDYPKHAFKDQEKEMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCHHHCCHHHHHH
TKEILFKYVLNNKFLWYIAFANVFVYFVRYGVVDWAPTYLTEAKGFSPEDSRWSYFLYEY
HHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCEEEEEEE
AGIPGTILCGWISDRFFKSRRAPAGVLFMAGVFIAVLVYWLNPAGHPLIDNIALISIGFL
CCCCHHEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
IYGPVMLIGLQAIDLAPKKAAGTAAGLTGFFGYIGGSAFANAIMGYVVDRFDWNGGFIML
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHH
ISSCVLSIVFLAMTWNTGKRAEHV
HHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8012593; 9384377 [H]