Click here to switch to the map view.

The map label for this gene is dcK [H]

Identifier: 154684533

GI number: 154684533

Start: 23535

End: 24188

Strand: Reverse

Name: dcK [H]

Synonym: RBAM_000190

Alternate gene names: 154684533

Gene position: 24188-23535 (Counterclockwise)

Preceding gene: 154684534

Following gene: 154684532

Centisome position: 0.62

GC content: 43.27

Gene sequence:

>654_bases
ATGAAAGACATTCATATTCCAAACAACGCCATTATAACAGTAGCGGGAACGGTAGGAGTCGGAAAATCGACTTTGACCAA
AGCTTTAGCAAAACGGCTCGGGTTTCATACCTCACTCGAGGAAGTGGATGAAAACCCTTATTTAGAGAAGTTTTATCACG
ATTTTGAACGTTGGAGCTTCCATTTACAAATTTATTTTCTGGCTGAGCGGTTCAAAGAGCAGAAAAACATGTTTGAATCA
GGCGGCGGATTCGTGCAGGACCGTTCGATTTATGAAGATACAGGCATATTCGCAAAAATGCATGCCGATAAAGGAACCAT
GTCGCTGACAGATTACACAACATACACAAGCCTATTTGAGGCGATGGTCATGACGCCGTACTTCCCGCATCCTGATGTTT
TGATCTATTTAGAAGGCGACCTTGAAAACATTATAAACCGGATTGAAAAGCGGGGCCGCGAGATGGAGCTGCAGACAAAC
CGCTCTTATTGGGAAGAGATGTATACACGGTACGAAGACTGGATCAGCGGTTTTAACGCCTGCCCTGTGCTGAAAGTGCG
CATTGAAGATTATGACCTTGAAGCTGATGAACAGTCACTGGAACCTTTGATCGAAAAAATCAGTCACGTGATCAACGAAA
ACAGAAATAAATAA

Upstream 100 bases:

>100_bases
CGGATATATCTGTACTGACCATTGACGGTGATACTGAAGACTTTGTTTTGAATAAGACAGACTATGAAAGAATTGCCCGT
CAGGTAAAGGAGCTTATTAA

Downstream 100 bases:

>100_bases
AAACAGCAAAGCGATTTTCCCCGGACAGAGAAAATCGCTTTTTTTGCATATAAAAAATCCGCTGCATCACATGCAGCGGA
CAAAACAATCTCCAATATAT

Product: deoxyadenosine/deoxycytidine kinase

Products: NA

Alternate protein names: dAK/dCK [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKDIHIPNNAIITVAGTVGVGKSTLTKALAKRLGFHTSLEEVDENPYLEKFYHDFERWSFHLQIYFLAERFKEQKNMFES
GGGFVQDRSIYEDTGIFAKMHADKGTMSLTDYTTYTSLFEAMVMTPYFPHPDVLIYLEGDLENIINRIEKRGREMELQTN
RSYWEEMYTRYEDWISGFNACPVLKVRIEDYDLEADEQSLEPLIEKISHVINENRNK

Sequences:

>Translated_217_residues
MKDIHIPNNAIITVAGTVGVGKSTLTKALAKRLGFHTSLEEVDENPYLEKFYHDFERWSFHLQIYFLAERFKEQKNMFES
GGGFVQDRSIYEDTGIFAKMHADKGTMSLTDYTTYTSLFEAMVMTPYFPHPDVLIYLEGDLENIINRIEKRGREMELQTN
RSYWEEMYTRYEDWISGFNACPVLKVRIEDYDLEADEQSLEPLIEKISHVINENRNK
>Mature_217_residues
MKDIHIPNNAIITVAGTVGVGKSTLTKALAKRLGFHTSLEEVDENPYLEKFYHDFERWSFHLQIYFLAERFKEQKNMFES
GGGFVQDRSIYEDTGIFAKMHADKGTMSLTDYTTYTSLFEAMVMTPYFPHPDVLIYLEGDLENIINRIEKRGREMELQTN
RSYWEEMYTRYEDWISGFNACPVLKVRIEDYDLEADEQSLEPLIEKISHVINENRNK

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the n

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.74; =2.7.1.76 [H]

Molecular weight: Translated: 25463; Mature: 25463

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDIHIPNNAIITVAGTVGVGKSTLTKALAKRLGFHTSLEEVDENPYLEKFYHDFERWSF
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHEE
HLQIYFLAERFKEQKNMFESGGGFVQDRSIYEDTGIFAKMHADKGTMSLTDYTTYTSLFE
EEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEECCCCCEEEHHHHHHHHHHH
AMVMTPYFPHPDVLIYLEGDLENIINRIEKRGREMELQTNRSYWEEMYTRYEDWISGFNA
HHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCCC
CPVLKVRIEDYDLEADEQSLEPLIEKISHVINENRNK
CCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKDIHIPNNAIITVAGTVGVGKSTLTKALAKRLGFHTSLEEVDENPYLEKFYHDFERWSF
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHEE
HLQIYFLAERFKEQKNMFESGGGFVQDRSIYEDTGIFAKMHADKGTMSLTDYTTYTSLFE
EEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEECCCCCEEEHHHHHHHHHHH
AMVMTPYFPHPDVLIYLEGDLENIINRIEKRGREMELQTNRSYWEEMYTRYEDWISGFNA
HHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCCC
CPVLKVRIEDYDLEADEQSLEPLIEKISHVINENRNK
CCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]