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The map label for this gene is nuoC

Identifier: 154248550

GI number: 154248550

Start: 5118861

End: 5119490

Strand: Reverse

Name: nuoC

Synonym: Xaut_4631

Alternate gene names: 154248550

Gene position: 5119490-5118861 (Counterclockwise)

Preceding gene: 154248551

Following gene: 154248549

Centisome position: 96.43

GC content: 65.56

Gene sequence:

>630_bases
ATGGACGAGACCCTCAACGACCTCGCGGCGCACGTATCGGCGGCCCTTTCGGGCGCCGTGCTCGGCTCTCTCGTGGCCCA
TGGCGAGCTGACGCTGCAGATCGATCCGGCGCAGATCGTCAAGGTGGCCACCTTCCTGCGGGATGATCCGGCCTGCCTGT
TCCACTGCATCGTGGACGTGTGCGGCGTGGACTATCCGGCCCGCGAGAAGCGGTTTGACGTGGTCTACCACCTGCTGTCG
TTGAAGCAGAACGTGCGCATCCGCCTGAAGGTGGAGACCGACGAGGACACCCCGGTTCCCTCCATCTGCTCGGTCTTTCC
CGGTGCCAACTGGTTCGAGCGGGAGGCCTATGACATGTATGGCATCCTGTTCACCGGACACCCGGAACTGCGCCGACTGC
TCACCGACTACGGCTTCGACGGGCATCCCCTGCGCAAGGACTTCCCGACCACGGGCTTCGTGGAGGTGCGCTACGACGAC
GAGCAGAAGCGCGTGGTCTACGAGCCGGTGCGCCTGCCGCAGGAATTCCGCAACTTCGACTTCCTCTCCCCGTGGGAGGG
CGTGGAATACGTCCTTCCCGGTGACGAGAAGGCCTCGGGCCAGCCGCCCGTTCCCCCCAAGGCCGGCTGA

Upstream 100 bases:

>100_bases
CTGCCCGCCCACTGCGGAAGCGCTGCTGTATGGCGTGCTGCTGCTGCAGAAGAAGATCCGCCGCATCGGCACCATCGAGC
GCTGAGCCGGGAGCATTTCG

Downstream 100 bases:

>100_bases
GGGAGCGCCTTATGGTTGACATCGCCGACGAGATGAAGCCGGCCGACAAGGTCCGTAACTTCCAGATCAATTTCGGCCCG
CAGCACCCTGCTGCGCATGG

Product: NADH (or F420H2) dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MDETLNDLAAHVSAALSGAVLGSLVAHGELTLQIDPAQIVKVATFLRDDPACLFHCIVDVCGVDYPAREKRFDVVYHLLS
LKQNVRIRLKVETDEDTPVPSICSVFPGANWFEREAYDMYGILFTGHPELRRLLTDYGFDGHPLRKDFPTTGFVEVRYDD
EQKRVVYEPVRLPQEFRNFDFLSPWEGVEYVLPGDEKASGQPPVPPKAG

Sequences:

>Translated_209_residues
MDETLNDLAAHVSAALSGAVLGSLVAHGELTLQIDPAQIVKVATFLRDDPACLFHCIVDVCGVDYPAREKRFDVVYHLLS
LKQNVRIRLKVETDEDTPVPSICSVFPGANWFEREAYDMYGILFTGHPELRRLLTDYGFDGHPLRKDFPTTGFVEVRYDD
EQKRVVYEPVRLPQEFRNFDFLSPWEGVEYVLPGDEKASGQPPVPPKAG
>Mature_209_residues
MDETLNDLAAHVSAALSGAVLGSLVAHGELTLQIDPAQIVKVATFLRDDPACLFHCIVDVCGVDYPAREKRFDVVYHLLS
LKQNVRIRLKVETDEDTPVPSICSVFPGANWFEREAYDMYGILFTGHPELRRLLTDYGFDGHPLRKDFPTTGFVEVRYDD
EQKRVVYEPVRLPQEFRNFDFLSPWEGVEYVLPGDEKASGQPPVPPKAG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=160, Percent_Identity=58.75, Blast_Score=204, Evalue=6e-53,
Organism=Escherichia coli, GI145693162, Length=169, Percent_Identity=34.9112426035503, Blast_Score=99, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71990788, Length=185, Percent_Identity=48.6486486486487, Blast_Score=189, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI32563621, Length=185, Percent_Identity=48.6486486486487, Blast_Score=189, Evalue=9e-49,
Organism=Drosophila melanogaster, GI24656494, Length=203, Percent_Identity=50.7389162561576, Blast_Score=205, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_XANP2 (A7IPA5)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001419508.1
- ProteinModelPortal:   A7IPA5
- SMR:   A7IPA5
- STRING:   A7IPA5
- GeneID:   5424063
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_4631
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   VVYEPVR
- ProtClustDB:   CLSK980354
- BioCyc:   XAUT78245:XAUT_4631-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 23537; Mature: 23537

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDETLNDLAAHVSAALSGAVLGSLVAHGELTLQIDPAQIVKVATFLRDDPACLFHCIVDV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHH
CGVDYPAREKRFDVVYHLLSLKQNVRIRLKVETDEDTPVPSICSVFPGANWFEREAYDMY
HCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHCCCCCCHHHHHHHEE
GILFTGHPELRRLLTDYGFDGHPLRKDFPTTGFVEVRYDDEQKRVVYEPVRLPQEFRNFD
EEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECHHCCCHHHHCCC
FLSPWEGVEYVLPGDEKASGQPPVPPKAG
CCCCCCCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDETLNDLAAHVSAALSGAVLGSLVAHGELTLQIDPAQIVKVATFLRDDPACLFHCIVDV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHH
CGVDYPAREKRFDVVYHLLSLKQNVRIRLKVETDEDTPVPSICSVFPGANWFEREAYDMY
HCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHCCCCCCHHHHHHHEE
GILFTGHPELRRLLTDYGFDGHPLRKDFPTTGFVEVRYDDEQKRVVYEPVRLPQEFRNFD
EEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECHHCCCHHHHCCC
FLSPWEGVEYVLPGDEKASGQPPVPPKAG
CCCCCCCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA