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The map label for this gene is nqo3 [H]

Identifier: 154248546

GI number: 154248546

Start: 5113328

End: 5115406

Strand: Reverse

Name: nqo3 [H]

Synonym: Xaut_4627

Alternate gene names: 154248546

Gene position: 5115406-5113328 (Counterclockwise)

Preceding gene: 154248547

Following gene: 154248545

Centisome position: 96.35

GC content: 69.12

Gene sequence:

>2079_bases
ATGGCGAAGATCGTCGTCGACGGCACAGAAGTCGATGTCCCGGCCGAATACACGCTGCTCCAGGCGTGCGAGGCGGCGGG
CGTCGAGATTCCGCGCTTCTGCTTCCATGAGCGGCTGTCCATTGCCGGCAATTGCCGCATGTGCCTGGTGGAAGTGAAGG
GCGGCCCGCCCAAGCCCACCGCGTCCTGCGCCATGGCGGTGAAGGACCTGCGTCCCGGCCCCAACGGCGAGCCGCCCGTG
GTGCTCACCAAGAGCCCCATGGTGAAGAAGGCGCGCGAAGGGGTGATGGAGTTCCTGCTCATCAACCACCCGCTGGATTG
CCCGATCTGCGACCAGGGCGGCGAGTGCGACCTGCAGGACCAGGCCATGGCCTATGGCGCGGACACCTCGCGCTTCGCCG
AGAACAAGCGCGCGGTCGAAGACAAGTACATCGGCCCCCTGGTGCGGACCTCCATGAACCGGTGCATCCAGTGCACCCGC
TGCGTGCGCTTCTCCACGGAAGTCGCCGGTGTGCCCGACCTCGGTGCCATCGGCCGCGGCGAGGACATGGAGATCACCAC
CTATCTCGAGCACGCCATGCGCTCGGAGATGCAGGGCAACGTGGCGGACCTGTGCCCGGTGGGCGCGCTCACCCACAAGC
CCTACCAGTTCCATGCCCGGCCGTGGGAGCTGATCAAGACCGAGTCCATCGACGTGATGGACGCGGTGGGCTCCAACATC
CGCATCGACACCCGCGGCCGCGAGGTCATGCGCATCCTGCCGCGCAACAACGACGTCGTGAACGAGGAGTGGATCTCCGA
TAAGTCCCGCTATGTGTGGGACGGCCTGAAGGTCCAGCGCCTCGACCGGCCCTATGTGCGCAAGGATAGCCGGCTGGTCG
CCGCATCCTGGAGCGAGGCGTTCGCCGCCATCGCCGCCAAGGTGAAGGCTGCGCCCGCGGCGAAGATCGGCGCCATCATC
GGCGACCTCGCCAGCGTGGAAGAGGTCTTCGCCCTCAAGACGCTGATCGGCAAGCTGGGTTCGGCCAACATCGACTGTCG
CCAGGATGGCGCGGCGCTTGATCCTGCGCTGGGCCGAGCGACCTATGTGTTCAACCCCACCATCGCCGGCATCGACGAGG
CGGACGCCATCCTGCTGGTGGGCACGGATCCGCGCCACGAGGCCTCGGTCCTCAATGCGCGCCTGCGCAAGCGTTGGCGG
CAGGGCGGGCTGAAGGTGGGCCTCATCGGCGCCAAGGTGGACCTCACCTACCCCTATGAATATCTCGGCGCCGGCCCGGA
CAGCCTGTCCGATCTCGCCGGCACCGGCGCCTTTGGCGAGGTGCTGCGCAAGGCTGAGCGTCCGCTCATCATCGTCGGGC
AGGGTGCTCTCGCGCGGTCGGACGGTGCAGCCGTGCTGGCGCTGACGGCCCGAGTGGCGGTTGCCTGCGGTGCGGTGAAG
GACGGCTGGAACGGCTTCGCGGTGCTCCACACTGCCGCGGCCCGCGTCGGTGCTCTTGACGTGGGCGCGGTGCCCGGCGC
CGGTGGGCTCGATGTTGCGGCCATGACCGCTCCGGGCGGGCTCGACGTTGCCTTCCTCCTGGGCGCCGACGAGGTGGCTG
TCGCCCCCGGCGCCTTCGTGGTCTATCTCGGCACCCATGGCGACACCGGGGCGCACCGGGCGGACGTGATCCTTCCCGGC
GCGGCCTATCCGGAAAAGTCCGGCCTCTATGTGAACACGGAAGGCCGGGTGCAGTTCGCCAACCGCGCCGCCTTCCCGCC
CGGTGAGGCCCGCGAGGACTGGGCCATCCTGCGCGCCCTGTCGGACGTGCTCGGCCAGACCCTGCCGTTCGACAACGTCC
TGGCCTTGCGCGCCCAGCTGGTCGCGGCCTATCCCCACCTCGGCCACATCGACGAGGTGGCGGCGGCCGATCCGGCGGCG
GTGGCCACCCTTGCGCAGGCGGGCGGCACCGTGGACAAGGCGGCGTTCGCGCTGCCCATCGATGATTTCTTCCTCACCAA
CCCCATCGCCCGCGCCTCCGCGGTAATGGCCGAATGCTCTGCCCTGCGCCTTGCGGCGACGGCGCAGGCAGCGGAGTGA

Upstream 100 bases:

>100_bases
GCGCGTCGCGACAGGCGGGAAGGGGACTGACACGGGAGGCTGGGCGCGCTGCGCTGGGTTTCCCGCCGCGCATGGCGCGG
CACAAGGCGAGGTGGAAGTG

Downstream 100 bases:

>100_bases
CGGGGATGGCGGCACAGGTGAACGGGACAGCTGCAAGCGGCACGGGATCGAGGACATGAACTGGCAGGATACCCTTATCC
AGGTGCTGATCATCCTCGGG

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I, chain 3; NDH-1, chain 3 [H]

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MAKIVVDGTEVDVPAEYTLLQACEAAGVEIPRFCFHERLSIAGNCRMCLVEVKGGPPKPTASCAMAVKDLRPGPNGEPPV
VLTKSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMAYGADTSRFAENKRAVEDKYIGPLVRTSMNRCIQCTR
CVRFSTEVAGVPDLGAIGRGEDMEITTYLEHAMRSEMQGNVADLCPVGALTHKPYQFHARPWELIKTESIDVMDAVGSNI
RIDTRGREVMRILPRNNDVVNEEWISDKSRYVWDGLKVQRLDRPYVRKDSRLVAASWSEAFAAIAAKVKAAPAAKIGAII
GDLASVEEVFALKTLIGKLGSANIDCRQDGAALDPALGRATYVFNPTIAGIDEADAILLVGTDPRHEASVLNARLRKRWR
QGGLKVGLIGAKVDLTYPYEYLGAGPDSLSDLAGTGAFGEVLRKAERPLIIVGQGALARSDGAAVLALTARVAVACGAVK
DGWNGFAVLHTAAARVGALDVGAVPGAGGLDVAAMTAPGGLDVAFLLGADEVAVAPGAFVVYLGTHGDTGAHRADVILPG
AAYPEKSGLYVNTEGRVQFANRAAFPPGEAREDWAILRALSDVLGQTLPFDNVLALRAQLVAAYPHLGHIDEVAAADPAA
VATLAQAGGTVDKAAFALPIDDFFLTNPIARASAVMAECSALRLAATAQAAE

Sequences:

>Translated_692_residues
MAKIVVDGTEVDVPAEYTLLQACEAAGVEIPRFCFHERLSIAGNCRMCLVEVKGGPPKPTASCAMAVKDLRPGPNGEPPV
VLTKSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMAYGADTSRFAENKRAVEDKYIGPLVRTSMNRCIQCTR
CVRFSTEVAGVPDLGAIGRGEDMEITTYLEHAMRSEMQGNVADLCPVGALTHKPYQFHARPWELIKTESIDVMDAVGSNI
RIDTRGREVMRILPRNNDVVNEEWISDKSRYVWDGLKVQRLDRPYVRKDSRLVAASWSEAFAAIAAKVKAAPAAKIGAII
GDLASVEEVFALKTLIGKLGSANIDCRQDGAALDPALGRATYVFNPTIAGIDEADAILLVGTDPRHEASVLNARLRKRWR
QGGLKVGLIGAKVDLTYPYEYLGAGPDSLSDLAGTGAFGEVLRKAERPLIIVGQGALARSDGAAVLALTARVAVACGAVK
DGWNGFAVLHTAAARVGALDVGAVPGAGGLDVAAMTAPGGLDVAFLLGADEVAVAPGAFVVYLGTHGDTGAHRADVILPG
AAYPEKSGLYVNTEGRVQFANRAAFPPGEAREDWAILRALSDVLGQTLPFDNVLALRAQLVAAYPHLGHIDEVAAADPAA
VATLAQAGGTVDKAAFALPIDDFFLTNPIARASAVMAECSALRLAATAQAAE
>Mature_691_residues
AKIVVDGTEVDVPAEYTLLQACEAAGVEIPRFCFHERLSIAGNCRMCLVEVKGGPPKPTASCAMAVKDLRPGPNGEPPVV
LTKSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMAYGADTSRFAENKRAVEDKYIGPLVRTSMNRCIQCTRC
VRFSTEVAGVPDLGAIGRGEDMEITTYLEHAMRSEMQGNVADLCPVGALTHKPYQFHARPWELIKTESIDVMDAVGSNIR
IDTRGREVMRILPRNNDVVNEEWISDKSRYVWDGLKVQRLDRPYVRKDSRLVAASWSEAFAAIAAKVKAAPAAKIGAIIG
DLASVEEVFALKTLIGKLGSANIDCRQDGAALDPALGRATYVFNPTIAGIDEADAILLVGTDPRHEASVLNARLRKRWRQ
GGLKVGLIGAKVDLTYPYEYLGAGPDSLSDLAGTGAFGEVLRKAERPLIIVGQGALARSDGAAVLALTARVAVACGAVKD
GWNGFAVLHTAAARVGALDVGAVPGAGGLDVAAMTAPGGLDVAFLLGADEVAVAPGAFVVYLGTHGDTGAHRADVILPGA
AYPEKSGLYVNTEGRVQFANRAAFPPGEAREDWAILRALSDVLGQTLPFDNVLALRAQLVAAYPHLGHIDEVAAADPAAV
ATLAQAGGTVDKAAFALPIDDFFLTNPIARASAVMAECSALRLAATAQAAE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=702, Percent_Identity=50.7122507122507, Blast_Score=674, Evalue=0.0,
Organism=Escherichia coli, GI145693161, Length=387, Percent_Identity=30.749354005168, Blast_Score=199, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17565758, Length=695, Percent_Identity=50.3597122302158, Blast_Score=633, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566231, Length=611, Percent_Identity=51.7184942716858, Blast_Score=575, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI193209088, Length=261, Percent_Identity=60.9195402298851, Blast_Score=325, Evalue=4e-89,
Organism=Drosophila melanogaster, GI24640559, Length=693, Percent_Identity=52.958152958153, Blast_Score=646, Evalue=0.0,
Organism=Drosophila melanogaster, GI24640557, Length=693, Percent_Identity=52.958152958153, Blast_Score=646, Evalue=0.0,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 73147; Mature: 73016

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIVVDGTEVDVPAEYTLLQACEAAGVEIPRFCFHERLSIAGNCRMCLVEVKGGPPKPT
CCEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCH
ASCAMAVKDLRPGPNGEPPVVLTKSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQD
HHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
QAMAYGADTSRFAENKRAVEDKYIGPLVRTSMNRCIQCTRCVRFSTEVAGVPDLGAIGRG
HHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EDMEITTYLEHAMRSEMQGNVADLCPVGALTHKPYQFHARPWELIKTESIDVMDAVGSNI
CCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEECCCCHHHHCCCCCHHHHHCCCCE
RIDTRGREVMRILPRNNDVVNEEWISDKSRYVWDGLKVQRLDRPYVRKDSRLVAASWSEA
EEECCCCCHHEECCCCCCCCCHHHHCCCCCEEECCCEEEECCCCCCCCCCEEEEECHHHH
FAAIAAKVKAAPAAKIGAIIGDLASVEEVFALKTLIGKLGSANIDCRQDGAALDPALGRA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCE
TYVFNPTIAGIDEADAILLVGTDPRHEASVLNARLRKRWRQGGLKVGLIGAKVDLTYPYE
EEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCHH
YLGAGPDSLSDLAGTGAFGEVLRKAERPLIIVGQGALARSDGAAVLALTARVAVACGAVK
HHCCCCCHHHHHHCCCHHHHHHHHCCCCEEEEECCCEECCCCCEEEHHHHHHHHHHCCCC
DGWNGFAVLHTAAARVGALDVGAVPGAGGLDVAAMTAPGGLDVAFLLGADEVAVAPGAFV
CCCCCEEHHHHHHHHHCCEECCCCCCCCCCCEEEEECCCCCCEEEEECCCCEEECCCEEE
VYLGTHGDTGAHRADVILPGAAYPEKSGLYVNTEGRVQFANRAAFPPGEAREDWAILRAL
EEEECCCCCCCCCCEEEECCCCCCCCCCEEEECCCCEEECCCCCCCCCCCHHHHHHHHHH
SDVLGQTLPFDNVLALRAQLVAAYPHLGHIDEVAAADPAAVATLAQAGGTVDKAAFALPI
HHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCEEEECC
DDFFLTNPIARASAVMAECSALRLAATAQAAE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKIVVDGTEVDVPAEYTLLQACEAAGVEIPRFCFHERLSIAGNCRMCLVEVKGGPPKPT
CEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCH
ASCAMAVKDLRPGPNGEPPVVLTKSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQD
HHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
QAMAYGADTSRFAENKRAVEDKYIGPLVRTSMNRCIQCTRCVRFSTEVAGVPDLGAIGRG
HHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EDMEITTYLEHAMRSEMQGNVADLCPVGALTHKPYQFHARPWELIKTESIDVMDAVGSNI
CCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEECCCCHHHHCCCCCHHHHHCCCCE
RIDTRGREVMRILPRNNDVVNEEWISDKSRYVWDGLKVQRLDRPYVRKDSRLVAASWSEA
EEECCCCCHHEECCCCCCCCCHHHHCCCCCEEECCCEEEECCCCCCCCCCEEEEECHHHH
FAAIAAKVKAAPAAKIGAIIGDLASVEEVFALKTLIGKLGSANIDCRQDGAALDPALGRA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCE
TYVFNPTIAGIDEADAILLVGTDPRHEASVLNARLRKRWRQGGLKVGLIGAKVDLTYPYE
EEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCHH
YLGAGPDSLSDLAGTGAFGEVLRKAERPLIIVGQGALARSDGAAVLALTARVAVACGAVK
HHCCCCCHHHHHHCCCHHHHHHHHCCCCEEEEECCCEECCCCCEEEHHHHHHHHHHCCCC
DGWNGFAVLHTAAARVGALDVGAVPGAGGLDVAAMTAPGGLDVAFLLGADEVAVAPGAFV
CCCCCEEHHHHHHHHHCCEECCCCCCCCCCCEEEEECCCCCCEEEEECCCCEEECCCEEE
VYLGTHGDTGAHRADVILPGAAYPEKSGLYVNTEGRVQFANRAAFPPGEAREDWAILRAL
EEEECCCCCCCCCCEEEECCCCCCCCCCEEEECCCCEEECCCCCCCCCCCHHHHHHHHHH
SDVLGQTLPFDNVLALRAQLVAAYPHLGHIDEVAAADPAAVATLAQAGGTVDKAAFALPI
HHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCEEEECC
DDFFLTNPIARASAVMAECSALRLAATAQAAE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1605643; 8422400 [H]