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The map label for this gene is nuoH [H]

Identifier: 154248545

GI number: 154248545

Start: 5112253

End: 5113272

Strand: Reverse

Name: nuoH [H]

Synonym: Xaut_4626

Alternate gene names: 154248545

Gene position: 5113272-5112253 (Counterclockwise)

Preceding gene: 154248546

Following gene: 154248544

Centisome position: 96.31

GC content: 63.82

Gene sequence:

>1020_bases
ATGAACTGGCAGGATACCCTTATCCAGGTGCTGATCATCCTCGGGCAGAGCCTGGCTCTGCTCGTGGCGCTCCTGATTTT
CATCGCCTTCATCCTGCTCGCCGATCGCAAGATCTGGGCGGCGGTGCAGCTGCGGCGCGGGCCGAACGTGGTGGGCCCCT
TCGGCCTGTTCCAGTCGTTCGCCGACCTTCTGAAGTTCGTGCTGAAGGAACCGACCATCCCGGCCGGCGCCAACAAGGCG
ATCTTCCTGCTTGCCCCGCTGGTGACCTGCGTTCTGGCGCTTGCTGCCTGGGCGGTTGTGCCGCTGGCGAAGGGCTGGGT
GATCGCCGACCTGAACGTGGGCGTGCTCTATATCTTCGCGATCTCGTCGCTGGGCGTGTACGGCATCATCATGGGCGGCT
GGGCGTCCAACTCGAAGTATCCCTTCCTGGCGGCGCTCCGCTCCGCCGCGCAGATGGTGTCCTACGAGGTTTCCATCGGC
TTCGTGATCATCACGGTGCTGATGTGCGCGGGCTCGCTGAACCTGACCCAGATCGTTGAGGCGCAGAACGGCCGGTTCGG
GCTGCTGAACTGGTATTTCCTGCCGCTCCTGCCCATGTTCGTCATCTTCTTCATCTCGGCCCTTGCCGAGACCAACCGCC
CGCCCTTCGACCTCGTGGAAGCGGAGTCGGAGCTGGTGGCCGGCTTCATGACCGAGTACGGCTCGACGCCCTACCTGCTG
TTCATGCTCGGCGAGTACGTGGCCATCATGACCATGTGCGCCATGGCGACCATCCTGTTCCTCGGCGGCTGGCTCTCGCC
GCTGCCGTTCCCGCCCTTCACCTGGGTGCCGGGCCTGGTGTGGTTCGTCATCAAGCTGTGCTTCATGTTCTTCCTCTTCG
CCATGGCGAAGGCCATGGTGCCGCGTTATCGCTACGACCAGCTCATGCGACTCGGCTGGAAGGTGTTCCTGCCGATCTCC
CTGGTTGCCGTGGTGGTGGTCGCGAGCGTCCTGCACTTCACCGGGATGGCGCCGCGATGA

Upstream 100 bases:

>100_bases
TGCTCTGCCCTGCGCCTTGCGGCGACGGCGCAGGCAGCGGAGTGACGGGGATGGCGGCACAGGTGAACGGGACAGCTGCA
AGCGGCACGGGATCGAGGAC

Downstream 100 bases:

>100_bases
CCGCGCCCGTCCTTCTTCCGCACTGCCCTTCGGGAGAGCGTTCATGAAGCTCGATCAGGCCGCGCGCGGTCTCTTCCTGA
CGGAGCTCGTCTCCGGCTTC

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MNWQDTLIQVLIILGQSLALLVALLIFIAFILLADRKIWAAVQLRRGPNVVGPFGLFQSFADLLKFVLKEPTIPAGANKA
IFLLAPLVTCVLALAAWAVVPLAKGWVIADLNVGVLYIFAISSLGVYGIIMGGWASNSKYPFLAALRSAAQMVSYEVSIG
FVIITVLMCAGSLNLTQIVEAQNGRFGLLNWYFLPLLPMFVIFFISALAETNRPPFDLVEAESELVAGFMTEYGSTPYLL
FMLGEYVAIMTMCAMATILFLGGWLSPLPFPPFTWVPGLVWFVIKLCFMFFLFAMAKAMVPRYRYDQLMRLGWKVFLPIS
LVAVVVVASVLHFTGMAPR

Sequences:

>Translated_339_residues
MNWQDTLIQVLIILGQSLALLVALLIFIAFILLADRKIWAAVQLRRGPNVVGPFGLFQSFADLLKFVLKEPTIPAGANKA
IFLLAPLVTCVLALAAWAVVPLAKGWVIADLNVGVLYIFAISSLGVYGIIMGGWASNSKYPFLAALRSAAQMVSYEVSIG
FVIITVLMCAGSLNLTQIVEAQNGRFGLLNWYFLPLLPMFVIFFISALAETNRPPFDLVEAESELVAGFMTEYGSTPYLL
FMLGEYVAIMTMCAMATILFLGGWLSPLPFPPFTWVPGLVWFVIKLCFMFFLFAMAKAMVPRYRYDQLMRLGWKVFLPIS
LVAVVVVASVLHFTGMAPR
>Mature_339_residues
MNWQDTLIQVLIILGQSLALLVALLIFIAFILLADRKIWAAVQLRRGPNVVGPFGLFQSFADLLKFVLKEPTIPAGANKA
IFLLAPLVTCVLALAAWAVVPLAKGWVIADLNVGVLYIFAISSLGVYGIIMGGWASNSKYPFLAALRSAAQMVSYEVSIG
FVIITVLMCAGSLNLTQIVEAQNGRFGLLNWYFLPLLPMFVIFFISALAETNRPPFDLVEAESELVAGFMTEYGSTPYLL
FMLGEYVAIMTMCAMATILFLGGWLSPLPFPPFTWVPGLVWFVIKLCFMFFLFAMAKAMVPRYRYDQLMRLGWKVFLPIS
LVAVVVVASVLHFTGMAPR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=294, Percent_Identity=43.5374149659864, Blast_Score=233, Evalue=2e-61,
Organism=Escherichia coli, GI1788618, Length=332, Percent_Identity=39.1566265060241, Blast_Score=245, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 37432; Mature: 37432

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWQDTLIQVLIILGQSLALLVALLIFIAFILLADRKIWAAVQLRRGPNVVGPFGLFQSF
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHH
ADLLKFVLKEPTIPAGANKAIFLLAPLVTCVLALAAWAVVPLAKGWVIADLNVGVLYIFA
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHH
ISSLGVYGIIMGGWASNSKYPFLAALRSAAQMVSYEVSIGFVIITVLMCAGSLNLTQIVE
HHHCCHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AQNGRFGLLNWYFLPLLPMFVIFFISALAETNRPPFDLVEAESELVAGFMTEYGSTPYLL
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
FMLGEYVAIMTMCAMATILFLGGWLSPLPFPPFTWVPGLVWFVIKLCFMFFLFAMAKAMV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PRYRYDQLMRLGWKVFLPISLVAVVVVASVLHFTGMAPR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNWQDTLIQVLIILGQSLALLVALLIFIAFILLADRKIWAAVQLRRGPNVVGPFGLFQSF
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHH
ADLLKFVLKEPTIPAGANKAIFLLAPLVTCVLALAAWAVVPLAKGWVIADLNVGVLYIFA
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHH
ISSLGVYGIIMGGWASNSKYPFLAALRSAAQMVSYEVSIGFVIITVLMCAGSLNLTQIVE
HHHCCHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AQNGRFGLLNWYFLPLLPMFVIFFISALAETNRPPFDLVEAESELVAGFMTEYGSTPYLL
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
FMLGEYVAIMTMCAMATILFLGGWLSPLPFPPFTWVPGLVWFVIKLCFMFFLFAMAKAMV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PRYRYDQLMRLGWKVFLPISLVAVVVVASVLHFTGMAPR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA