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The map label for this gene is nuoI [H]

Identifier: 154248544

GI number: 154248544

Start: 5111721

End: 5112209

Strand: Reverse

Name: nuoI [H]

Synonym: Xaut_4625

Alternate gene names: 154248544

Gene position: 5112209-5111721 (Counterclockwise)

Preceding gene: 154248545

Following gene: 154248543

Centisome position: 96.29

GC content: 64.21

Gene sequence:

>489_bases
ATGAAGCTCGATCAGGCCGCGCGCGGTCTCTTCCTGACGGAGCTCGTCTCCGGCTTCTTCCTCGCCATGCGCTATTTCTT
CAAGCCCAAGGCGACGCTGAACTATCCCTTCGAGAAGGGGCCGCTCTCTCCGCGCTTTCGCGGCGAGCATGCGCTGCGCC
GCTATCCCAACGGGGAAGAGCGCTGCATCGCCTGCAAGCTGTGCGAGGCCATCTGCCCGGCGCAGGCCATCACCATCGAG
GCCGGTCCGCGCCGCAATGACGGCACGCGCCGCACCACCCGTTACGACATCGACATGGTGAAGTGCATCTATTGCGGCTT
CTGCCAGGAGGCTTGCCCGGTGGATGCCATCGTCGAGGGGCCGAACTTCGAATTCGCCGCCGAGACCCGCGAAGAGCTTT
ATTACGACAAGGAAAAGCTGCTCGCGAACGGCGACCGGTGGGAGCGCGAGATCGCGCGGTCCATCGCCATGGATGCGCCG
TATCGCTGA

Upstream 100 bases:

>100_bases
GTTGCCGTGGTGGTGGTCGCGAGCGTCCTGCACTTCACCGGGATGGCGCCGCGATGACCGCGCCCGTCCTTCTTCCGCAC
TGCCCTTCGGGAGAGCGTTC

Downstream 100 bases:

>100_bases
GCGCGCTTCCGGCCGGTGGCCGGAAGGTCGGGATTGATGTTGTCGGCTTTCGGCCGGCAGTGGGGGACAGCCGAGCGTCA
CGCGTCCTGCGCGACGACAC

Product: NADH dehydrogenase subunit I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I; NDH-1 subunit I [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MKLDQAARGLFLTELVSGFFLAMRYFFKPKATLNYPFEKGPLSPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITIE
AGPRRNDGTRRTTRYDIDMVKCIYCGFCQEACPVDAIVEGPNFEFAAETREELYYDKEKLLANGDRWEREIARSIAMDAP
YR

Sequences:

>Translated_162_residues
MKLDQAARGLFLTELVSGFFLAMRYFFKPKATLNYPFEKGPLSPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITIE
AGPRRNDGTRRTTRYDIDMVKCIYCGFCQEACPVDAIVEGPNFEFAAETREELYYDKEKLLANGDRWEREIARSIAMDAP
YR
>Mature_162_residues
MKLDQAARGLFLTELVSGFFLAMRYFFKPKATLNYPFEKGPLSPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITIE
AGPRRNDGTRRTTRYDIDMVKCIYCGFCQEACPVDAIVEGPNFEFAAETREELYYDKEKLLANGDRWEREIARSIAMDAP
YR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=159, Percent_Identity=76.7295597484277, Blast_Score=253, Evalue=7e-68,
Organism=Escherichia coli, GI1788617, Length=142, Percent_Identity=39.4366197183099, Blast_Score=102, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17555194, Length=160, Percent_Identity=70.625, Blast_Score=236, Evalue=4e-63,
Organism=Drosophila melanogaster, GI17864306, Length=159, Percent_Identity=74.8427672955975, Blast_Score=251, Evalue=2e-67,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18654; Mature: 18654

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDQAARGLFLTELVSGFFLAMRYFFKPKATLNYPFEKGPLSPRFRGEHALRRYPNGEE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHHHCCCCCH
RCIACKLCEAICPAQAITIEAGPRRNDGTRRTTRYDIDMVKCIYCGFCQEACPVDAIVEG
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEECC
PNFEFAAETREELYYDKEKLLANGDRWEREIARSIAMDAPYR
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKLDQAARGLFLTELVSGFFLAMRYFFKPKATLNYPFEKGPLSPRFRGEHALRRYPNGEE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHHHCCCCCH
RCIACKLCEAICPAQAITIEAGPRRNDGTRRTTRYDIDMVKCIYCGFCQEACPVDAIVEG
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEECC
PNFEFAAETREELYYDKEKLLANGDRWEREIARSIAMDAPYR
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA