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The map label for this gene is panC

Identifier: 154248462

GI number: 154248462

Start: 5020252

End: 5021109

Strand: Direct

Name: panC

Synonym: Xaut_4542

Alternate gene names: 154248462

Gene position: 5020252-5021109 (Clockwise)

Preceding gene: 154248459

Following gene: 154248466

Centisome position: 94.56

GC content: 69.93

Gene sequence:

>858_bases
ATGGCGACATTGCCGAAGGTGGTGGGGCGCGTTCGCGACCTCAGGGCGCGAGTGGCGGAATTCCGCGCGGAAGGCGCGCG
GGTGGCGCTGGTGCCCACCATGGGCGCGCTGCACGCCGGCCATGTGGCGCTGGCGGAAAAGGCACGCGAGCTGGCCCAGC
GTACCGTGGTGTCCATCTTCGTGAACCCCACCCAGTTCGCCCCGCACGAGGACTTCTCGCAATATCCCCGCTCGCTGGAG
GCCGACCTCTACAAGCTGGCGGACGTGGGGGTGGACCTCGTCTACGCACCGACGCCAACCGAGATGTACCCGGCCGGCTT
CGTCACCCGCATTGCGGTGGGCGGCCCCTCGGAAGGGCTTGAGACGGATTTCCGCCCGCATTTCTTCGGCGGCGTCGCCA
CCGTGGTGGGCAAGCTGTTCATCCAGTGCGCGCCGGACTACGCCATGTTCGGCGAGAAGGACTACCAGCAGCTCAAGGTC
GTGACGCGCCTGTCGCGGGACCTGGACCTCGGCGTCGAGGTGGTGGGCCTGCCCACCATCCGGGAAGAGGACGGCCTCGC
CCTGTCCTCCCGCAACGCCTATCTGGACGAAGAGCAGCGCACCATCGCGCCGGTGATCTACACTGCCCTCTCCCGCGCCG
CCGACGCGATCCGCGCCGGCACCGCGCCGCAGGCGGCGGTCAGCGTGGCCCGCGGCATGATCGAGGCGCTGGGCCTGAAG
GTGGACTATGTGGCCGCCCGCAACGCCGACACCCTCGCGCCCCTGAAGGAAGGGCCGGAGGCCGGCCGCGAACCCATCCG
CCTTTTGGCGGCGGCGTGGCTCGGCGAGACCCGGCTCATCGACAACATCCCGGTGTGA

Upstream 100 bases:

>100_bases
CCAACTCAGCAGTTGATGCGCGGACACCGACGCCCTATCTCCTCCCGGCGCTGCCGGCCTGAACGCGTGTTCCGGCGGGC
GGCAGGAGAGGCTTGAGACC

Downstream 100 bases:

>100_bases
GCCTGGCCGTGCGAGGCGCGCGTCGCCTCACACGGCGCCCATGTAGCTCGCGGCGAAACCGATCACCACCAGCACGAGGC
TCACGATCAGGACCGTCAGG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MATLPKVVGRVRDLRARVAEFRAEGARVALVPTMGALHAGHVALAEKARELAQRTVVSIFVNPTQFAPHEDFSQYPRSLE
ADLYKLADVGVDLVYAPTPTEMYPAGFVTRIAVGGPSEGLETDFRPHFFGGVATVVGKLFIQCAPDYAMFGEKDYQQLKV
VTRLSRDLDLGVEVVGLPTIREEDGLALSSRNAYLDEEQRTIAPVIYTALSRAADAIRAGTAPQAAVSVARGMIEALGLK
VDYVAARNADTLAPLKEGPEAGREPIRLLAAAWLGETRLIDNIPV

Sequences:

>Translated_285_residues
MATLPKVVGRVRDLRARVAEFRAEGARVALVPTMGALHAGHVALAEKARELAQRTVVSIFVNPTQFAPHEDFSQYPRSLE
ADLYKLADVGVDLVYAPTPTEMYPAGFVTRIAVGGPSEGLETDFRPHFFGGVATVVGKLFIQCAPDYAMFGEKDYQQLKV
VTRLSRDLDLGVEVVGLPTIREEDGLALSSRNAYLDEEQRTIAPVIYTALSRAADAIRAGTAPQAAVSVARGMIEALGLK
VDYVAARNADTLAPLKEGPEAGREPIRLLAAAWLGETRLIDNIPV
>Mature_284_residues
ATLPKVVGRVRDLRARVAEFRAEGARVALVPTMGALHAGHVALAEKARELAQRTVVSIFVNPTQFAPHEDFSQYPRSLEA
DLYKLADVGVDLVYAPTPTEMYPAGFVTRIAVGGPSEGLETDFRPHFFGGVATVVGKLFIQCAPDYAMFGEKDYQQLKVV
TRLSRDLDLGVEVVGLPTIREEDGLALSSRNAYLDEEQRTIAPVIYTALSRAADAIRAGTAPQAAVSVARGMIEALGLKV
DYVAARNADTLAPLKEGPEAGREPIRLLAAAWLGETRLIDNIPV

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=272, Percent_Identity=47.0588235294118, Blast_Score=233, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6322046, Length=300, Percent_Identity=37.3333333333333, Blast_Score=174, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 30767; Mature: 30635

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLPKVVGRVRDLRARVAEFRAEGARVALVPTMGALHAGHVALAEKARELAQRTVVSIF
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEE
VNPTQFAPHEDFSQYPRSLEADLYKLADVGVDLVYAPTPTEMYPAGFVTRIAVGGPSEGL
ECCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEECCCCCCC
ETDFRPHFFGGVATVVGKLFIQCAPDYAMFGEKDYQQLKVVTRLSRDLDLGVEVVGLPTI
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCE
REEDGLALSSRNAYLDEEQRTIAPVIYTALSRAADAIRAGTAPQAAVSVARGMIEALGLK
ECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
VDYVAARNADTLAPLKEGPEAGREPIRLLAAAWLGETRLIDNIPV
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHCCCCCCC
>Mature Secondary Structure 
ATLPKVVGRVRDLRARVAEFRAEGARVALVPTMGALHAGHVALAEKARELAQRTVVSIF
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEE
VNPTQFAPHEDFSQYPRSLEADLYKLADVGVDLVYAPTPTEMYPAGFVTRIAVGGPSEGL
ECCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEECCCCCCC
ETDFRPHFFGGVATVVGKLFIQCAPDYAMFGEKDYQQLKVVTRLSRDLDLGVEVVGLPTI
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCE
REEDGLALSSRNAYLDEEQRTIAPVIYTALSRAADAIRAGTAPQAAVSVARGMIEALGLK
ECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
VDYVAARNADTLAPLKEGPEAGREPIRLLAAAWLGETRLIDNIPV
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA