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The map label for this gene is hfq [H]

Identifier: 154248313

GI number: 154248313

Start: 4870306

End: 4870626

Strand: Reverse

Name: hfq [H]

Synonym: Xaut_4393

Alternate gene names: 154248313

Gene position: 4870626-4870306 (Counterclockwise)

Preceding gene: 154248314

Following gene: 154248312

Centisome position: 91.74

GC content: 52.96

Gene sequence:

>321_bases
GTGGCGGCAGCACATTATTTTTGTGCGTCTGCGACGGACTTAACGCCCAAAAAAACGGATACGAAAATGGCGGCGGAACG
GACACAAAATCTCCAAGACACCTTCCTCAATCACGTCCGCAAGAACAAGACGCCCCTCACCATCTTCCTGGTGAACGGGG
TGAAGTTGCAGGGCGTCGTCACTTGGTTCGATAATTTTTGCGTACTCTTGCGTCGCGACGGACATTCCCAGCTTGTTTAC
AAGCACGCGATTTCCACCATTATGCCCGGTCATCCGGTGCAATTGTTCGATCCCACCGACGACGTGGGCGAGAAGGCTTA
A

Upstream 100 bases:

>100_bases
TTTCCGAAATTTTCTGAGGTATCCACGGCCGCGCTCATGTTGCGGGGCAAAATAATATTGCGCCGCCATGGAGCTGTGCC
ATTCTAGGAGGCCAACTCCC

Downstream 100 bases:

>100_bases
AGCAGCGTGGAGCGTGCCACCGGCAAGGGGTCCAGAACGACGTTGAAGACAGGGTCCAAGCTGGGGTCCAAAGGGGGCGC
CACCACTCGGGGCGTTTCAG

Product: RNA chaperone Hfq

Products: NA

Alternate protein names: Nif-regulating factor [H]

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MAAAHYFCASATDLTPKKTDTKMAAERTQNLQDTFLNHVRKNKTPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVY
KHAISTIMPGHPVQLFDPTDDVGEKA

Sequences:

>Translated_106_residues
MAAAHYFCASATDLTPKKTDTKMAAERTQNLQDTFLNHVRKNKTPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVY
KHAISTIMPGHPVQLFDPTDDVGEKA
>Mature_105_residues
AAAHYFCASATDLTPKKTDTKMAAERTQNLQDTFLNHVRKNKTPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYK
HAISTIMPGHPVQLFDPTDDVGEKA

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Seems to

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=67, Percent_Identity=53.7313432835821, Blast_Score=82, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 11887; Mature: 11756

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAHYFCASATDLTPKKTDTKMAAERTQNLQDTFLNHVRKNKTPLTIFLVNGVKLQGVV
CCCCCCEECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCEEEEHHH
TWFDNFCVLLRRDGHSQLVYKHAISTIMPGHPVQLFDPTDDVGEKA
HHHCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
AAAHYFCASATDLTPKKTDTKMAAERTQNLQDTFLNHVRKNKTPLTIFLVNGVKLQGVV
CCCCCEECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCEEEEHHH
TWFDNFCVLLRRDGHSQLVYKHAISTIMPGHPVQLFDPTDDVGEKA
HHHCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8197116 [H]