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The map label for this gene is hflX [H]

Identifier: 154248312

GI number: 154248312

Start: 4868761

End: 4870134

Strand: Reverse

Name: hflX [H]

Synonym: Xaut_4392

Alternate gene names: 154248312

Gene position: 4870134-4868761 (Counterclockwise)

Preceding gene: 154248313

Following gene: 154248310

Centisome position: 91.73

GC content: 69.94

Gene sequence:

>1374_bases
GTGGACGTTTCCGTATCTGCACCTGCGCGGGAAGAGGGCCGCGGCGGCATTGACCGCCGTGCGCCGCCGACGCGGTGCGC
CGTCATCACGCCGGCGCTGACGAAACGTGCCACCCGCGGCGCGCCGGAACGGCGCAGCCCACAGTCGCGGCTGGAGGAGG
CGGTGGGTCTTGCCGCCGCCATCGACCTCGACGTGGTCTACTCCGCCACCATTCCCCTGTCGGAGATCCGCCCCGCCACC
TTCCTCGGCTCGGGGAAGGTGGAGGAACTGGAAGGCGTGGTGCGTGCCGAGGCGGTGGACCTCGTGTTCTTCGACGCGGC
GCTCTCGCCGGTGCAGCAGCGCAACCTGGAAAAGGCTTGGTCCGCCAAGGTGGTGGACCGCACGGCGCTGATTCTCGAAA
TCTTCGGCATGCGCGCCCGCACCAAGGAAGGCGCGCTGCAGGTGGAACTGGCCCACCTCAATTACCAGCGTTCGCGCCTG
GTGCGCTCCTGGACCCATCTGGAGCGCCAGCGCGGCGGTTTCGGCTTCCTTGGCGGTCCCGGTGAGACCCAGATCGAGGC
CGACCGCCGGCTCATCGGCGAGCGCATTGTGCGCATCGAGAAGGAGCTGGAGCAGGTCAAGCGCACCCGCGGCCTGCACC
GGGCCAGCCGCAAGCGCGTGCCCTATCCCATCGTCGCGCTGGTGGGCTACACCAATGCCGGCAAGTCCACCTTGTTCAAC
CGCCTGACCCGAGCGGAGGTGATGGCGAAAGACCTGCTCTTCGCCACCCTCGATCCGACGCTTCGGGCGGTGGACCTGCC
CCACGGCACCCGCATCATCCTCTCCGACACGGTGGGCTTCATCTCCGAGCTGCCGACCCAGCTGGTGGCCGCCTTCCGCG
CCACGCTGGAGGAGGTGCTGGAGGCTGACCTCATCCTGCACGTGCGCGACATCTCCCATCCGGACACCGACGCCCAGGCC
GCCGACGTGTCCGACGTGCTGGAGGATCTGGGCGTCGATCCCCAGCCGGGTGGGCGCGTGATCGAGGTCTGGAACAAGAT
CGACCGGCTGGCGCCGGACGAACGCGAGCAGGTGGAAAACCGGGCCGCTCGTGGCGGCGCCGAAGCGCCGGTGCCGGTTT
CCGCGCTGACCGGGGAGGGGACCGACGACCTGCTCGGCCTCATCGAGCGCCGCATCACCGCTGGACGGGTGACTGTCTCG
GTGACGCTGGCGGCGGAGGACGGGGAGGGGCTCGGCTGGCTCTATCGCCACGGCGAGGTGCTGGAGCGCACCACGGACGA
GGATGGCGCCATCCACGTGGCCCTGCGCATTCCGCCCGATCGCGCTGGGCTGATCACCCGCCGCTTCGGCGCACGGCGCG
TGCATCCGACCTGA

Upstream 100 bases:

>100_bases
AGGGGGCGCCACCACTCGGGGCGTTTCAGCTCAGAGTGCTGCCGAAACCCGCGGGGGCGTGGCCGATGCCGCGACCTCCG
GCGGTTCCGGCGACTTGCCG

Downstream 100 bases:

>100_bases
GCAACTCAGCCTGCCGCGCCTTTGGCCGGCCGGTTTCAGTGAGGCAGGGCAGGGGCTGGAACGCCGTCGCGCTCACGCGC
CTTCCCGCTCCTTCTGCTTC

Product: small GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MDVSVSAPAREEGRGGIDRRAPPTRCAVITPALTKRATRGAPERRSPQSRLEEAVGLAAAIDLDVVYSATIPLSEIRPAT
FLGSGKVEELEGVVRAEAVDLVFFDAALSPVQQRNLEKAWSAKVVDRTALILEIFGMRARTKEGALQVELAHLNYQRSRL
VRSWTHLERQRGGFGFLGGPGETQIEADRRLIGERIVRIEKELEQVKRTRGLHRASRKRVPYPIVALVGYTNAGKSTLFN
RLTRAEVMAKDLLFATLDPTLRAVDLPHGTRIILSDTVGFISELPTQLVAAFRATLEEVLEADLILHVRDISHPDTDAQA
ADVSDVLEDLGVDPQPGGRVIEVWNKIDRLAPDEREQVENRAARGGAEAPVPVSALTGEGTDDLLGLIERRITAGRVTVS
VTLAAEDGEGLGWLYRHGEVLERTTDEDGAIHVALRIPPDRAGLITRRFGARRVHPT

Sequences:

>Translated_457_residues
MDVSVSAPAREEGRGGIDRRAPPTRCAVITPALTKRATRGAPERRSPQSRLEEAVGLAAAIDLDVVYSATIPLSEIRPAT
FLGSGKVEELEGVVRAEAVDLVFFDAALSPVQQRNLEKAWSAKVVDRTALILEIFGMRARTKEGALQVELAHLNYQRSRL
VRSWTHLERQRGGFGFLGGPGETQIEADRRLIGERIVRIEKELEQVKRTRGLHRASRKRVPYPIVALVGYTNAGKSTLFN
RLTRAEVMAKDLLFATLDPTLRAVDLPHGTRIILSDTVGFISELPTQLVAAFRATLEEVLEADLILHVRDISHPDTDAQA
ADVSDVLEDLGVDPQPGGRVIEVWNKIDRLAPDEREQVENRAARGGAEAPVPVSALTGEGTDDLLGLIERRITAGRVTVS
VTLAAEDGEGLGWLYRHGEVLERTTDEDGAIHVALRIPPDRAGLITRRFGARRVHPT
>Mature_457_residues
MDVSVSAPAREEGRGGIDRRAPPTRCAVITPALTKRATRGAPERRSPQSRLEEAVGLAAAIDLDVVYSATIPLSEIRPAT
FLGSGKVEELEGVVRAEAVDLVFFDAALSPVQQRNLEKAWSAKVVDRTALILEIFGMRARTKEGALQVELAHLNYQRSRL
VRSWTHLERQRGGFGFLGGPGETQIEADRRLIGERIVRIEKELEQVKRTRGLHRASRKRVPYPIVALVGYTNAGKSTLFN
RLTRAEVMAKDLLFATLDPTLRAVDLPHGTRIILSDTVGFISELPTQLVAAFRATLEEVLEADLILHVRDISHPDTDAQA
ADVSDVLEDLGVDPQPGGRVIEVWNKIDRLAPDEREQVENRAARGGAEAPVPVSALTGEGTDDLLGLIERRITAGRVTVS
VTLAAEDGEGLGWLYRHGEVLERTTDEDGAIHVALRIPPDRAGLITRRFGARRVHPT

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=298, Percent_Identity=37.248322147651, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI310133116, Length=296, Percent_Identity=37.1621621621622, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI310124269, Length=277, Percent_Identity=37.9061371841155, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI310124267, Length=277, Percent_Identity=37.9061371841155, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI310124171, Length=277, Percent_Identity=37.9061371841155, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI310124169, Length=277, Percent_Identity=37.9061371841155, Blast_Score=154, Evalue=2e-37,
Organism=Escherichia coli, GI1790615, Length=363, Percent_Identity=46.2809917355372, Blast_Score=286, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI17561038, Length=391, Percent_Identity=32.2250639386189, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24650079, Length=419, Percent_Identity=32.4582338902148, Blast_Score=167, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50078; Mature: 50078

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVSVSAPAREEGRGGIDRRAPPTRCAVITPALTKRATRGAPERRSPQSRLEEAVGLAAA
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
IDLDVVYSATIPLSEIRPATFLGSGKVEELEGVVRAEAVDLVFFDAALSPVQQRNLEKAW
EEEEEEEECCCCHHHCCCCEEECCCCHHHHHHHHHHHHHHHEEEHHHHCHHHHHHHHHHH
SAKVVDRTALILEIFGMRARTKEGALQVELAHLNYQRSRLVRSWTHLERQRGGFGFLGGP
HHHHHHHHHHHHHHHCCHHCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHHCCCCEECCCC
GETQIEADRRLIGERIVRIEKELEQVKRTRGLHRASRKRVPYPIVALVGYTNAGKSTLFN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHH
RLTRAEVMAKDLLFATLDPTLRAVDLPHGTRIILSDTVGFISELPTQLVAAFRATLEEVL
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
EADLILHVRDISHPDTDAQAADVSDVLEDLGVDPQPGGRVIEVWNKIDRLAPDEREQVEN
HHHHEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
RAARGGAEAPVPVSALTGEGTDDLLGLIERRITAGRVTVSVTLAAEDGEGLGWLYRHGEV
HHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHCCHH
LERTTDEDGAIHVALRIPPDRAGLITRRFGARRVHPT
HHHCCCCCCEEEEEEECCCCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MDVSVSAPAREEGRGGIDRRAPPTRCAVITPALTKRATRGAPERRSPQSRLEEAVGLAAA
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
IDLDVVYSATIPLSEIRPATFLGSGKVEELEGVVRAEAVDLVFFDAALSPVQQRNLEKAW
EEEEEEEECCCCHHHCCCCEEECCCCHHHHHHHHHHHHHHHEEEHHHHCHHHHHHHHHHH
SAKVVDRTALILEIFGMRARTKEGALQVELAHLNYQRSRLVRSWTHLERQRGGFGFLGGP
HHHHHHHHHHHHHHHCCHHCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHHCCCCEECCCC
GETQIEADRRLIGERIVRIEKELEQVKRTRGLHRASRKRVPYPIVALVGYTNAGKSTLFN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHH
RLTRAEVMAKDLLFATLDPTLRAVDLPHGTRIILSDTVGFISELPTQLVAAFRATLEEVL
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
EADLILHVRDISHPDTDAQAADVSDVLEDLGVDPQPGGRVIEVWNKIDRLAPDEREQVEN
HHHHEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
RAARGGAEAPVPVSALTGEGTDDLLGLIERRITAGRVTVSVTLAAEDGEGLGWLYRHGEV
HHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHCCHH
LERTTDEDGAIHVALRIPPDRAGLITRRFGARRVHPT
HHHCCCCCCEEEEEEECCCCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]