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The map label for this gene is fabH [H]

Identifier: 154248305

GI number: 154248305

Start: 4860877

End: 4861851

Strand: Direct

Name: fabH [H]

Synonym: Xaut_4385

Alternate gene names: 154248305

Gene position: 4860877-4861851 (Clockwise)

Preceding gene: 154248304

Following gene: 154248306

Centisome position: 91.56

GC content: 69.13

Gene sequence:

>975_bases
GTGAGCGGAATCAGGTCCGTCGCCCGGGGATCCGGGTCCTATCTCCCCGAGAGGGTGCTCTCGAACGACGATCTCGCGCG
GCGCATCGACACGACCGACGACTGGATCGTGCAGCGCACCGGCATCCGCCAGCGCCATATCGCCGCCGAGGGCGAGTTCA
CCTCGCATCTCGCGCTGAAGGCGGCCGAGCGGGCGCTCGCCGACGCAGGCTTTGCCGCGCGCGACATTGACCTCATCATC
CTCGCCACCGCCACGCCGGACCAGACTTTCCCCGCCACCTCGGTGACGGTGCAGGCGGAGCTGGGCATCACCCGCGGCGC
CGCCTTCGACGTGCAGGCGGTGTGCTCCGGCTTCGTGTTCGCCCTTGCCACCGCCGATGCCTATCTGAAGACCGGCGCCT
TCGACCGGGCGCTGGTGATCGGGGCGGAGACCTTTTCCCGCATCCTCGACTGGGAGGATCGCGGCACCTGCGTGCTGTTC
GGCGACGGGGCAGGGGCCATGGTGCTGGAAGCGGTGCGGGAGGACGACGCCCACGGCGCCGGCCTTCTCACCTCGCACCT
GCGCTCGGACGGGCGGCACCGCACCAAGCTGTTCGTGGACGGCGGCCCCTCCACCACGGGAACCGTGGGCCACCTGCGCA
TGGAGGGCCGCGAGGTGTTCAAGCATGCGGTGGGCATGATCACCGACGTGATCGAGGACGCCTTCGCCGCCACCGGCGAA
AGCGCCGCGAGCATCGACTGGTTCGTGCCCCATCAGGCCAATCGCCGCATTATCGACGCCAGCGCGCTGAAGCTGGGCAT
CGCCCCCGAAAAGGTGGTGACCACGGTGGACCAGCACGGAAATACCTCAGCCGCCTCCATTCCGCTGGCCTTCGACCTTG
CGGTCAGGGACGGGCGCATCAAGCGGGGCGATCTGGTGCTGCTGGAGGCCATGGGCGGAGGTTTCACCTGGGGATCGGCC
CTCCTGCGCTGGTAA

Upstream 100 bases:

>100_bases
GCAACGAGCTTCTCGCGCGTATTGAAAAGAGCCTCGTCGGCCGCCAGCCGCCGGACGTAGCAGCATGCCGGCCGCAGGCC
GCAGGGGTGGAAGGCCAATC

Downstream 100 bases:

>100_bases
TTGATTTAAGTCGTTGACCGACCTTGGCAAGCGCGGCTAGTTTGCGTCGCACATCCTTCGCCAGTACTGGGTCGCTTTAC
GGCGTGCGGCGATCTTTCCG

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSGIRSVARGSGSYLPERVLSNDDLARRIDTTDDWIVQRTGIRQRHIAAEGEFTSHLALKAAERALADAGFAARDIDLII
LATATPDQTFPATSVTVQAELGITRGAAFDVQAVCSGFVFALATADAYLKTGAFDRALVIGAETFSRILDWEDRGTCVLF
GDGAGAMVLEAVREDDAHGAGLLTSHLRSDGRHRTKLFVDGGPSTTGTVGHLRMEGREVFKHAVGMITDVIEDAFAATGE
SAASIDWFVPHQANRRIIDASALKLGIAPEKVVTTVDQHGNTSAASIPLAFDLAVRDGRIKRGDLVLLEAMGGGFTWGSA
LLRW

Sequences:

>Translated_324_residues
MSGIRSVARGSGSYLPERVLSNDDLARRIDTTDDWIVQRTGIRQRHIAAEGEFTSHLALKAAERALADAGFAARDIDLII
LATATPDQTFPATSVTVQAELGITRGAAFDVQAVCSGFVFALATADAYLKTGAFDRALVIGAETFSRILDWEDRGTCVLF
GDGAGAMVLEAVREDDAHGAGLLTSHLRSDGRHRTKLFVDGGPSTTGTVGHLRMEGREVFKHAVGMITDVIEDAFAATGE
SAASIDWFVPHQANRRIIDASALKLGIAPEKVVTTVDQHGNTSAASIPLAFDLAVRDGRIKRGDLVLLEAMGGGFTWGSA
LLRW
>Mature_323_residues
SGIRSVARGSGSYLPERVLSNDDLARRIDTTDDWIVQRTGIRQRHIAAEGEFTSHLALKAAERALADAGFAARDIDLIIL
ATATPDQTFPATSVTVQAELGITRGAAFDVQAVCSGFVFALATADAYLKTGAFDRALVIGAETFSRILDWEDRGTCVLFG
DGAGAMVLEAVREDDAHGAGLLTSHLRSDGRHRTKLFVDGGPSTTGTVGHLRMEGREVFKHAVGMITDVIEDAFAATGES
AASIDWFVPHQANRRIIDASALKLGIAPEKVVTTVDQHGNTSAASIPLAFDLAVRDGRIKRGDLVLLEAMGGGFTWGSAL
LRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=316, Percent_Identity=50, Blast_Score=309, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34531; Mature: 34400

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGIRSVARGSGSYLPERVLSNDDLARRIDTTDDWIVQRTGIRQRHIAAEGEFTSHLALK
CCCHHHHHCCCCCCCHHHHCCCCHHHHHCCCCCHHHEECCCCCHHHEECCCCHHHHHHHH
AAERALADAGFAARDIDLIILATATPDQTFPATSVTVQAELGITRGAAFDVQAVCSGFVF
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
ALATADAYLKTGAFDRALVIGAETFSRILDWEDRGTCVLFGDGAGAMVLEAVREDDAHGA
HHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCCCC
GLLTSHLRSDGRHRTKLFVDGGPSTTGTVGHLRMEGREVFKHAVGMITDVIEDAFAATGE
HHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCC
SAASIDWFVPHQANRRIIDASALKLGIAPEKVVTTVDQHGNTSAASIPLAFDLAVRDGRI
CCCEEEEECCCCCCCEEEEHHHEEECCCCHHHHHHHHCCCCCCCEECCEEEEEEECCCCC
KRGDLVLLEAMGGGFTWGSALLRW
CCCCEEEEEECCCCEEHHHHHHCC
>Mature Secondary Structure 
SGIRSVARGSGSYLPERVLSNDDLARRIDTTDDWIVQRTGIRQRHIAAEGEFTSHLALK
CCHHHHHCCCCCCCHHHHCCCCHHHHHCCCCCHHHEECCCCCHHHEECCCCHHHHHHHH
AAERALADAGFAARDIDLIILATATPDQTFPATSVTVQAELGITRGAAFDVQAVCSGFVF
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
ALATADAYLKTGAFDRALVIGAETFSRILDWEDRGTCVLFGDGAGAMVLEAVREDDAHGA
HHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCCCC
GLLTSHLRSDGRHRTKLFVDGGPSTTGTVGHLRMEGREVFKHAVGMITDVIEDAFAATGE
HHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCC
SAASIDWFVPHQANRRIIDASALKLGIAPEKVVTTVDQHGNTSAASIPLAFDLAVRDGRI
CCCEEEEECCCCCCCEEEEHHHEEECCCCHHHHHHHHCCCCCCCEECCEEEEEEECCCCC
KRGDLVLLEAMGGGFTWGSALLRW
CCCCEEEEEECCCCEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]