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The map label for this gene is moaC

Identifier: 154248293

GI number: 154248293

Start: 4849678

End: 4850166

Strand: Reverse

Name: moaC

Synonym: Xaut_4373

Alternate gene names: 154248293

Gene position: 4850166-4849678 (Counterclockwise)

Preceding gene: 154248294

Following gene: 154248292

Centisome position: 91.36

GC content: 69.73

Gene sequence:

>489_bases
ATGGCGAGCCTGACCCATATCGATGCCGAGGGCTCGGCCCGCATGGTGGACGTGTCCGACAAGGCCGCCACCACCCGCGA
GGCGCTGGCCGAGGGGCGCGTGGCCATGGCGCCGGCGACCCTTGAGCTCATCCTCTCCGGCAACGCCAAGAAGGGCGACG
TGATGGGCGTCGCGCGCCTCGCCGGCATCATGGCCGCCAAGCGCACCCATGAGCTCATCCCCCTGTGCCACCCGCTGATG
CTCACCAAGGTGGAGGTGGAGGTCGTGCCCGATTCCGCCCTGCCGGGCCTTCATGTCACCGCGCGGGCCAAGACCACGGG
CCAGACCGGCGTGGAGATGGAGGCGCTGACCGCGGTCTCGGTGGCCTGCCTCACCATCTACGACATGGCCAAGGCGGCCG
ACCGTGGCATGCGCATTGAAGGGATCCGGCTTCTGGAGAAATCCGGCGGCGCCAGCGGGCATTTCCGCGCGGAACCGCCC
ACGGACTGA

Upstream 100 bases:

>100_bases
GCCCCGGCGATCTTCTGTCTGCCTTGCCAAGGTGGACAGGACCCGCCGCGGGCGCCATCTTCCGTCCCGCACGAAACGAT
TCCGGGACGCACCGACGGCC

Downstream 100 bases:

>100_bases
AGAGGCCGAACCACTGATGGAACCGAGCACGACAACGGGCGCCGGGAAGCCGGCGGGCAAGAAGGCGCCCCTCATGACCG
TCGAGGAGGCCATAAGCCTC

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MASLTHIDAEGSARMVDVSDKAATTREALAEGRVAMAPATLELILSGNAKKGDVMGVARLAGIMAAKRTHELIPLCHPLM
LTKVEVEVVPDSALPGLHVTARAKTTGQTGVEMEALTAVSVACLTIYDMAKAADRGMRIEGIRLLEKSGGASGHFRAEPP
TD

Sequences:

>Translated_162_residues
MASLTHIDAEGSARMVDVSDKAATTREALAEGRVAMAPATLELILSGNAKKGDVMGVARLAGIMAAKRTHELIPLCHPLM
LTKVEVEVVPDSALPGLHVTARAKTTGQTGVEMEALTAVSVACLTIYDMAKAADRGMRIEGIRLLEKSGGASGHFRAEPP
TD
>Mature_161_residues
ASLTHIDAEGSARMVDVSDKAATTREALAEGRVAMAPATLELILSGNAKKGDVMGVARLAGIMAAKRTHELIPLCHPLML
TKVEVEVVPDSALPGLHVTARAKTTGQTGVEMEALTAVSVACLTIYDMAKAADRGMRIEGIRLLEKSGGASGHFRAEPPT
D

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=158, Percent_Identity=57.5949367088608, Blast_Score=169, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI32566331, Length=151, Percent_Identity=44.3708609271523, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28574490, Length=159, Percent_Identity=49.685534591195, Blast_Score=146, Evalue=6e-36,
Organism=Drosophila melanogaster, GI28574492, Length=145, Percent_Identity=50.3448275862069, Blast_Score=132, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_XANP2 (A7INK0)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001419251.1
- ProteinModelPortal:   A7INK0
- SMR:   A7INK0
- STRING:   A7INK0
- GeneID:   5422936
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_4373
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   CLSK980266
- BioCyc:   XAUT78245:XAUT_4373-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 16930; Mature: 16799

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLTHIDAEGSARMVDVSDKAATTREALAEGRVAMAPATLELILSGNAKKGDVMGVARL
CCCCEEECCCCCEEEEECCCHHHHHHHHHHCCCEEECCEEEEEEEECCCCCCCHHHHHHH
AGIMAAKRTHELIPLCHPLMLTKVEVEVVPDSALPGLHVTARAKTTGQTGVEMEALTAVS
HHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHH
VACLTIYDMAKAADRGMRIEGIRLLEKSGGASGHFRAEPPTD
HHHHHHHHHHHHHHCCCEEEHEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASLTHIDAEGSARMVDVSDKAATTREALAEGRVAMAPATLELILSGNAKKGDVMGVARL
CCCEEECCCCCEEEEECCCHHHHHHHHHHCCCEEECCEEEEEEEECCCCCCCHHHHHHH
AGIMAAKRTHELIPLCHPLMLTKVEVEVVPDSALPGLHVTARAKTTGQTGVEMEALTAVS
HHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHH
VACLTIYDMAKAADRGMRIEGIRLLEKSGGASGHFRAEPPTD
HHHHHHHHHHHHHHCCCEEEHEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA