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The map label for this gene is ribE [H]

Identifier: 154248199

GI number: 154248199

Start: 4745975

End: 4746586

Strand: Direct

Name: ribE [H]

Synonym: Xaut_4279

Alternate gene names: 154248199

Gene position: 4745975-4746586 (Clockwise)

Preceding gene: 154248198

Following gene: 154248200

Centisome position: 89.4

GC content: 68.63

Gene sequence:

>612_bases
ATGTTCACCGGCATCGTCACCGACATGGGCGACCTCGTCGCCGTGGAGACGAAGGGGGAGGTCAAGACCCTCACCATCGC
CACCGCCTATGAGGCGGCGGGGATCGACGTGGGCGCCTCCATCGCCCATGCGGGGGTGTGCCTTACCGTCACCTCGGTGA
CGGCCGGCGGCCCGCGCGGCACCCTCTTCACCGTGGATGCCGGACCGGAGACGCTGGCGATCACCACCGTGGGCGGCTGG
ACGCCGGGCCAGCGCATCAATCTGGAGCGCTCGCTGAAGCTGGGCGACGAGCTGGGCGGCCATATGGTTTCCGGGCACGT
GGACAGCACCGCCAGGGTGGTGTCCCGGGAGGACCTCGGCTCCACCACGCGCTTCGTGTTCGAGGTGCCGGAACAGCTTG
CCCGTTTTGTCGCGGTGAAGGGGTCGGTGGGCCTCGATGGCACCTCCCTCACGGTCAACACGGTGGAGGGCAACACCTTC
TCCTGCCTGCTCATTCCCCATACGCTCGCGGTCACCACCTGGGGCGGCGTCAAGGCGGGGGACACGGTCAATTTCGAGGT
GGACCTCATGGCCCGCTATGCCGCCCGGCTTGCGGAGTTCCCCCGGGCCTAG

Upstream 100 bases:

>100_bases
GGCCGTCCGCTCGGCCGCCTTTTCGCCCCCGTGGGCTTCGCCGAGGTGGAGCGCGCCGAGCTTGGCGCCGACCGCCTCGT
GCGCTTGTGGAGACGCTGAC

Downstream 100 bases:

>100_bases
TACGCCTCGCGACCAATTCCGGCACCGCACGCGGTGCCAAACGGTTCTGGAGAGACAGTCCATGGTCACGACGCGCAAGG
AAAGCGCCGGCGACGCCTCG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MFTGIVTDMGDLVAVETKGEVKTLTIATAYEAAGIDVGASIAHAGVCLTVTSVTAGGPRGTLFTVDAGPETLAITTVGGW
TPGQRINLERSLKLGDELGGHMVSGHVDSTARVVSREDLGSTTRFVFEVPEQLARFVAVKGSVGLDGTSLTVNTVEGNTF
SCLLIPHTLAVTTWGGVKAGDTVNFEVDLMARYAARLAEFPRA

Sequences:

>Translated_203_residues
MFTGIVTDMGDLVAVETKGEVKTLTIATAYEAAGIDVGASIAHAGVCLTVTSVTAGGPRGTLFTVDAGPETLAITTVGGW
TPGQRINLERSLKLGDELGGHMVSGHVDSTARVVSREDLGSTTRFVFEVPEQLARFVAVKGSVGLDGTSLTVNTVEGNTF
SCLLIPHTLAVTTWGGVKAGDTVNFEVDLMARYAARLAEFPRA
>Mature_203_residues
MFTGIVTDMGDLVAVETKGEVKTLTIATAYEAAGIDVGASIAHAGVCLTVTSVTAGGPRGTLFTVDAGPETLAITTVGGW
TPGQRINLERSLKLGDELGGHMVSGHVDSTARVVSREDLGSTTRFVFEVPEQLARFVAVKGSVGLDGTSLTVNTVEGNTF
SCLLIPHTLAVTTWGGVKAGDTVNFEVDLMARYAARLAEFPRA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=190, Percent_Identity=39.4736842105263, Blast_Score=125, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319733, Length=208, Percent_Identity=36.5384615384615, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21098; Mature: 21098

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVTDMGDLVAVETKGEVKTLTIATAYEAAGIDVGASIAHAGVCLTVTSVTAGGPRG
CCCCEEECCCCEEEEECCCCEEEEEEEEEEECCCCCCCCHHHHCCEEEEEEEEECCCCCC
TLFTVDAGPETLAITTVGGWTPGQRINLERSLKLGDELGGHMVSGHVDSTARVVSREDLG
EEEEEECCCCEEEEEEECCCCCCCEECHHHHCCCCHHCCCEEEECCCCCHHHHHHHCCCC
STTRFVFEVPEQLARFVAVKGSVGLDGTSLTVNTVEGNTFSCLLIPHTLAVTTWGGVKAG
CHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEECCCEEEEEEEECEEEEEECCCCCCC
DTVNFEVDLMARYAARLAEFPRA
CEEEEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFTGIVTDMGDLVAVETKGEVKTLTIATAYEAAGIDVGASIAHAGVCLTVTSVTAGGPRG
CCCCEEECCCCEEEEECCCCEEEEEEEEEEECCCCCCCCHHHHCCEEEEEEEEECCCCCC
TLFTVDAGPETLAITTVGGWTPGQRINLERSLKLGDELGGHMVSGHVDSTARVVSREDLG
EEEEEECCCCEEEEEEECCCCCCCEECHHHHCCCCHHCCCEEEECCCCCHHHHHHHCCCC
STTRFVFEVPEQLARFVAVKGSVGLDGTSLTVNTVEGNTFSCLLIPHTLAVTTWGGVKAG
CHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEECCCEEEEEEEECEEEEEECCCCCCC
DTVNFEVDLMARYAARLAEFPRA
CEEEEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]