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The map label for this gene is ribD [H]

Identifier: 154248198

GI number: 154248198

Start: 4744822

End: 4745973

Strand: Direct

Name: ribD [H]

Synonym: Xaut_4278

Alternate gene names: 154248198

Gene position: 4744822-4745973 (Clockwise)

Preceding gene: 154248197

Following gene: 154248199

Centisome position: 89.37

GC content: 73.87

Gene sequence:

>1152_bases
ATGAGCGTGTCCCCCCTGTCCGCCCATCCCGTCACCTCGCCGGAGGACGACGAGCGGTTCATGGCCGAGGCCCTGAAGGT
GGGCCAGAGTGGGCTCGGGCGTACCTGGCCCAACCCCTCCGTGGGCGCCGTGGTGGTGCAGCATGTGGACGGCCGCCCGC
ACATCGTCGGCGCCGCCGCAACCGCGCCCACCGGCCGCCCCCATGCCGAGCCCATCGCCCTTGCCCAGGCGGGGGAGGCG
GCGCGGGGCTCGACGCTTTATGTGACGCTGGAGCCCTGCTCCCACCACGGCCGCACCCCGCCCTGCGCCGGCGCGGTGAT
CGCCGCAGGAGTGCGCCGGGTGGTGGCCGCCATCGAGGACCCGGACCACCGGGTAAAGGGGCGCGGCGTCGCCCGCCTGC
GCGCCGCCGGCATCTGGGTGACGGTGGGGGTCGGCGCCGAGCAGGCGCTGGCCGACCACGCCGGCCATATCCGCCGCGTC
ACCGAAGGCCGGCCCCATGTGCTTTTGAAGATGGCGGTTTCCGCCGACGGCAAGGCCGCTCTCGCCGGGCCCCGGCCGGC
GGTGGTCACCGGACCCGAAGCGCGGGCGAGGGCCCATCTCATGCGCGCCCATGCGGACGCCATCCTGGTGGGCCTGGGTA
CCGTGACGGCCGACGATCCCATGCTCACCTGCCGGCTGGAAGGCCATGAGGACCGTTCCCCGGTGCGCCTCGTGCTCGAC
AGCGGGCTCGATATTCCGCTTGAAAGCGCCCTGGTGCGTACTGCCAGCGATGTCCCGGTCTGGGTGATCGCGGCGGAGGA
TGCCCCGGCCGAGCGCGCCGCCGCCCTCATGGAACGCGGCGTGGAAGTGCTGCGCGCCCCGCGTGGCGGCATCGAGGGGC
GGTTGCACCTGCCGGCGGTGCTCAAGCTCTTGGGCCTTTTGGGCATCACCCGGCTGATGGTTGAGGGCGGCCCCGCCACC
GCCGCCGCCTTCCTGGAGGCGGGCCTGGTGGACGAGGTGGCGGTGTTCCACAGCCCGGTGCTGCTGGGGCCGGATGCCTA
TCATGCGCTGGCCGGCCGTCCGCTCGGCCGCCTTTTCGCCCCCGTGGGCTTCGCCGAGGTGGAGCGCGCCGAGCTTGGCG
CCGACCGCCTCGTGCGCTTGTGGAGACGCTGA

Upstream 100 bases:

>100_bases
AGCCCGAACTGGCACAGTCCGATGACGTGAAAGCCGAAGGCGGGGCTGAAGGCGGCCGGGACAAACCGAAGGCCGCCGGC
AAGCCGCCCCGGAGCGCCGA

Downstream 100 bases:

>100_bases
CATGTTCACCGGCATCGTCACCGACATGGGCGACCTCGTCGCCGTGGAGACGAAGGGGGAGGTCAAGACCCTCACCATCG
CCACCGCCTATGAGGCGGCG

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSVSPLSAHPVTSPEDDERFMAEALKVGQSGLGRTWPNPSVGAVVVQHVDGRPHIVGAAATAPTGRPHAEPIALAQAGEA
ARGSTLYVTLEPCSHHGRTPPCAGAVIAAGVRRVVAAIEDPDHRVKGRGVARLRAAGIWVTVGVGAEQALADHAGHIRRV
TEGRPHVLLKMAVSADGKAALAGPRPAVVTGPEARARAHLMRAHADAILVGLGTVTADDPMLTCRLEGHEDRSPVRLVLD
SGLDIPLESALVRTASDVPVWVIAAEDAPAERAAALMERGVEVLRAPRGGIEGRLHLPAVLKLLGLLGITRLMVEGGPAT
AAAFLEAGLVDEVAVFHSPVLLGPDAYHALAGRPLGRLFAPVGFAEVERAELGADRLVRLWRR

Sequences:

>Translated_383_residues
MSVSPLSAHPVTSPEDDERFMAEALKVGQSGLGRTWPNPSVGAVVVQHVDGRPHIVGAAATAPTGRPHAEPIALAQAGEA
ARGSTLYVTLEPCSHHGRTPPCAGAVIAAGVRRVVAAIEDPDHRVKGRGVARLRAAGIWVTVGVGAEQALADHAGHIRRV
TEGRPHVLLKMAVSADGKAALAGPRPAVVTGPEARARAHLMRAHADAILVGLGTVTADDPMLTCRLEGHEDRSPVRLVLD
SGLDIPLESALVRTASDVPVWVIAAEDAPAERAAALMERGVEVLRAPRGGIEGRLHLPAVLKLLGLLGITRLMVEGGPAT
AAAFLEAGLVDEVAVFHSPVLLGPDAYHALAGRPLGRLFAPVGFAEVERAELGADRLVRLWRR
>Mature_382_residues
SVSPLSAHPVTSPEDDERFMAEALKVGQSGLGRTWPNPSVGAVVVQHVDGRPHIVGAAATAPTGRPHAEPIALAQAGEAA
RGSTLYVTLEPCSHHGRTPPCAGAVIAAGVRRVVAAIEDPDHRVKGRGVARLRAAGIWVTVGVGAEQALADHAGHIRRVT
EGRPHVLLKMAVSADGKAALAGPRPAVVTGPEARARAHLMRAHADAILVGLGTVTADDPMLTCRLEGHEDRSPVRLVLDS
GLDIPLESALVRTASDVPVWVIAAEDAPAERAAALMERGVEVLRAPRGGIEGRLHLPAVLKLLGLLGITRLMVEGGPATA
AAFLEAGLVDEVAVFHSPVLLGPDAYHALAGRPLGRLFAPVGFAEVERAELGADRLVRLWRR

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=351, Percent_Identity=41.5954415954416, Blast_Score=229, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39940; Mature: 39808

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSPLSAHPVTSPEDDERFMAEALKVGQSGLGRTWPNPSVGAVVVQHVDGRPHIVGAAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEC
TAPTGRPHAEPIALAQAGEAARGSTLYVTLEPCSHHGRTPPCAGAVIAAGVRRVVAAIED
CCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
PDHRVKGRGVARLRAAGIWVTVGVGAEQALADHAGHIRRVTEGRPHVLLKMAVSADGKAA
CCCCCCCCCEEEEEECCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEE
LAGPRPAVVTGPEARARAHLMRAHADAILVGLGTVTADDPMLTCRLEGHEDRSPVRLVLD
ECCCCCCEEECCHHHHHHHHHHHHCCEEEEEECCEECCCCEEEEEECCCCCCCCEEEEEC
SGLDIPLESALVRTASDVPVWVIAAEDAPAERAAALMERGVEVLRAPRGGIEGRLHLPAV
CCCCCCHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHH
LKLLGLLGITRLMVEGGPATAAAFLEAGLVDEVAVFHSPVLLGPDAYHALAGRPLGRLFA
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHCCCEEECCCHHHHHHCCCHHHHHC
PVGFAEVERAELGADRLVRLWRR
CCCHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure 
SVSPLSAHPVTSPEDDERFMAEALKVGQSGLGRTWPNPSVGAVVVQHVDGRPHIVGAAA
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEC
TAPTGRPHAEPIALAQAGEAARGSTLYVTLEPCSHHGRTPPCAGAVIAAGVRRVVAAIED
CCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
PDHRVKGRGVARLRAAGIWVTVGVGAEQALADHAGHIRRVTEGRPHVLLKMAVSADGKAA
CCCCCCCCCEEEEEECCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEE
LAGPRPAVVTGPEARARAHLMRAHADAILVGLGTVTADDPMLTCRLEGHEDRSPVRLVLD
ECCCCCCEEECCHHHHHHHHHHHHCCEEEEEECCEECCCCEEEEEECCCCCCCCEEEEEC
SGLDIPLESALVRTASDVPVWVIAAEDAPAERAAALMERGVEVLRAPRGGIEGRLHLPAV
CCCCCCHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHH
LKLLGLLGITRLMVEGGPATAAAFLEAGLVDEVAVFHSPVLLGPDAYHALAGRPLGRLFA
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHCCCEEECCCHHHHHHCCCHHHHHC
PVGFAEVERAELGADRLVRLWRR
CCCHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]