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The map label for this gene is cycY [H]

Identifier: 154248050

GI number: 154248050

Start: 4570119

End: 4570721

Strand: Reverse

Name: cycY [H]

Synonym: Xaut_4129

Alternate gene names: 154248050

Gene position: 4570721-4570119 (Counterclockwise)

Preceding gene: 154248051

Following gene: 154248049

Centisome position: 86.09

GC content: 70.15

Gene sequence:

>603_bases
ATGAGCACGCCCGACGAGACGCCCGCCCCGGCGCGGCCCCGCCGCCGGCTGTGGCTGGTGGCCCTGCCGCTGGTGCTGTT
TTTGGCGCTGGCCGGCCTGTTCTTCTCCCGGCTTGAAACCGGAGGCGACCCCTCGCGCATCCCGTCCGCCCTGGTGGGCA
AGGCGGCGCCCCGGATCGCGCTGCCACCGCTCGACGGCCTGAATGGTCCCGGCGGCACACCTTTGCCGGGCATTGATCTT
GCGGCGCTTGCCGGCAAGCCGACGCTGGTGAATGTCTGGGCCTCCTGGTGCGGCCCCTGCCGGGACGAGCATCCGGTGCT
GATGCAGCTCGCCAAGGACGGCCGCTTCAACCTCGTGGGCATCAACTACAAGGACGCGCCGGAGAATGCCCGCCGCTTCC
TCGGCCAATATGGCCTGCCCTACCAGGCGGTGGGCGTGGATCCCAAGGGCCGCGCCGCCATCGACTGGGGCGTCTATGGT
GTGCCGGAGACCTTCGTGGTCGCCAGGGACGGCACCATCGCGCACAAATTCGTCGGCCCGCTGACGACCGAGGCGGTGAA
CACCACCCTCCTGCCGCTGATCGCCCGCCTGTCGGGAAACTGA

Upstream 100 bases:

>100_bases
CCGATTACGGCCGCCAGCGCCGGACGCTCGCCGATCTGGAGGCGCGCGGTATCGGCAAGAGGTCCCGCCGCGGGACGGGG
GATGCGCCGGGAGACGCGCC

Downstream 100 bases:

>100_bases
GCGACAGCCACAAGGGTGACGCCGGCGGCTACTGGATTTAAGGATTCCGCCATGGCCTTTTCCCCCGACGAGATCGAACG
CTACGCCCGCCACATCGTGC

Product: periplasmic protein thiol--disulfide oxidoreductase DsbE

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CycY [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSTPDETPAPARPRRRLWLVALPLVLFLALAGLFFSRLETGGDPSRIPSALVGKAAPRIALPPLDGLNGPGGTPLPGIDL
AALAGKPTLVNVWASWCGPCRDEHPVLMQLAKDGRFNLVGINYKDAPENARRFLGQYGLPYQAVGVDPKGRAAIDWGVYG
VPETFVVARDGTIAHKFVGPLTTEAVNTTLLPLIARLSGN

Sequences:

>Translated_200_residues
MSTPDETPAPARPRRRLWLVALPLVLFLALAGLFFSRLETGGDPSRIPSALVGKAAPRIALPPLDGLNGPGGTPLPGIDL
AALAGKPTLVNVWASWCGPCRDEHPVLMQLAKDGRFNLVGINYKDAPENARRFLGQYGLPYQAVGVDPKGRAAIDWGVYG
VPETFVVARDGTIAHKFVGPLTTEAVNTTLLPLIARLSGN
>Mature_199_residues
STPDETPAPARPRRRLWLVALPLVLFLALAGLFFSRLETGGDPSRIPSALVGKAAPRIALPPLDGLNGPGGTPLPGIDLA
ALAGKPTLVNVWASWCGPCRDEHPVLMQLAKDGRFNLVGINYKDAPENARRFLGQYGLPYQAVGVDPKGRAAIDWGVYGV
PETFVVARDGTIAHKFVGPLTTEAVNTTLLPLIARLSGN

Specific function: Required for disulfide bond formation in some periplasmic proteins. Also act as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur [

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=188, Percent_Identity=37.2340425531915, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21249; Mature: 21118

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPDETPAPARPRRRLWLVALPLVLFLALAGLFFSRLETGGDPSRIPSALVGKAAPRIA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEE
LPPLDGLNGPGGTPLPGIDLAALAGKPTLVNVWASWCGPCRDEHPVLMQLAKDGRFNLVG
CCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEE
INYKDAPENARRFLGQYGLPYQAVGVDPKGRAAIDWGVYGVPETFVVARDGTIAHKFVGP
CCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHHCC
LTTEAVNTTLLPLIARLSGN
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STPDETPAPARPRRRLWLVALPLVLFLALAGLFFSRLETGGDPSRIPSALVGKAAPRIA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEE
LPPLDGLNGPGGTPLPGIDLAALAGKPTLVNVWASWCGPCRDEHPVLMQLAKDGRFNLVG
CCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEE
INYKDAPENARRFLGQYGLPYQAVGVDPKGRAAIDWGVYGVPETFVVARDGTIAHKFVGP
CCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHHCC
LTTEAVNTTLLPLIARLSGN
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]