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The map label for this gene is cycZ [H]

Identifier: 154248051

GI number: 154248051

Start: 4570924

End: 4571655

Strand: Reverse

Name: cycZ [H]

Synonym: Xaut_4130

Alternate gene names: 154248051

Gene position: 4571655-4570924 (Counterclockwise)

Preceding gene: 154248052

Following gene: 154248050

Centisome position: 86.11

GC content: 68.58

Gene sequence:

>732_bases
ATGGCGATCCTCGACCTTGCCAACCCGGTCCGCTTCATGAGCCTGTCCGCCCGCATCCTGCCGTGGATCGCGGGGGCGGC
GGTGGTGACGCTCGCCGTCGGTTTCTTCCTCGCCTTCCGCGCCCCGCCCGATTACCAGCAGGGCGAGACGGTGCGCATCA
TGTACATCCACGTGCCGTTCGCGTGGCTTGGCCTGTTCGGCTATTCCATGATGGCGGCCTCCTCCATCGGCATCCTGGTC
TGGCGCCATCCGCTGGCGGACGTGGCCCACAAGGCCGCAGCGCCCGTGGGCGCCACCTTCACCGCTTTGTGCCTCGTCAC
CGGTGCGCTCTGGGGCCGGCCCATGTGGGGCACCTATTGGGTGTGGGACGCGCGCCTCACATCCATGCTGGTGCTGCTGC
TGCTCTATCTGGGCCTGATGGCCCTGCGCGCCGCCATCGACGACCCCAACCGCGCCGGGCGCGCTGCGGCGGTGCTGACT
TTGGTGGGCTTCATCAACGTGCCCATCGTGAAGTTCTCGGTGGACTGGTGGAACACGCTGCACCAGCCGGCCTCGGTGTT
CCGCATGGGCGGCTCCACCATCGAATCGAGCCTGCTGTGGCCGCTGCTGGTCTGCGCCATCGGCTTCACGCTGCTGTTCG
TGGCGCTGCACATGCTGGGCATGCGCACGGAAATCCTCCACCGCCGGGTGCAGGCGCTGGAAGCCCGCGCCGCCGCCGAG
GCCATGGCCTGA

Upstream 100 bases:

>100_bases
GGCTGGCCTGACCTTCCGGGCCCAACCGCCCCCCTGCGACACGAAATCCTGAACGGCGAGAGCGCTTCCCTCCGGCGCGC
GGGCGCTTTAGAACCGCGCC

Downstream 100 bases:

>100_bases
GCCGGCGGGATGAGCGATCCGAAATGAGCCACTTCGTCTTCATTGCCGCCTCCTATGGCGTCACCACGCTGGGCCTCGGC
CTGCTCGCCGCCTGGCTCCT

Product: heme exporter protein CcmC

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MAILDLANPVRFMSLSARILPWIAGAAVVTLAVGFFLAFRAPPDYQQGETVRIMYIHVPFAWLGLFGYSMMAASSIGILV
WRHPLADVAHKAAAPVGATFTALCLVTGALWGRPMWGTYWVWDARLTSMLVLLLLYLGLMALRAAIDDPNRAGRAAAVLT
LVGFINVPIVKFSVDWWNTLHQPASVFRMGGSTIESSLLWPLLVCAIGFTLLFVALHMLGMRTEILHRRVQALEARAAAE
AMA

Sequences:

>Translated_243_residues
MAILDLANPVRFMSLSARILPWIAGAAVVTLAVGFFLAFRAPPDYQQGETVRIMYIHVPFAWLGLFGYSMMAASSIGILV
WRHPLADVAHKAAAPVGATFTALCLVTGALWGRPMWGTYWVWDARLTSMLVLLLLYLGLMALRAAIDDPNRAGRAAAVLT
LVGFINVPIVKFSVDWWNTLHQPASVFRMGGSTIESSLLWPLLVCAIGFTLLFVALHMLGMRTEILHRRVQALEARAAAE
AMA
>Mature_242_residues
AILDLANPVRFMSLSARILPWIAGAAVVTLAVGFFLAFRAPPDYQQGETVRIMYIHVPFAWLGLFGYSMMAASSIGILVW
RHPLADVAHKAAAPVGATFTALCLVTGALWGRPMWGTYWVWDARLTSMLVLLLLYLGLMALRAAIDDPNRAGRAAAVLTL
VGFINVPIVKFSVDWWNTLHQPASVFRMGGSTIESSLLWPLLVCAIGFTLLFVALHMLGMRTEILHRRVQALEARAAAEA
MA

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=223, Percent_Identity=49.3273542600897, Blast_Score=196, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 26606; Mature: 26475

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILDLANPVRFMSLSARILPWIAGAAVVTLAVGFFLAFRAPPDYQQGETVRIMYIHVPF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCH
AWLGLFGYSMMAASSIGILVWRHPLADVAHKAAAPVGATFTALCLVTGALWGRPMWGTYW
HHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEE
VWDARLTSMLVLLLLYLGLMALRAAIDDPNRAGRAAAVLTLVGFINVPIVKFSVDWWNTL
EHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHHH
HQPASVFRMGGSTIESSLLWPLLVCAIGFTLLFVALHMLGMRTEILHRRVQALEARAAAE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMA
HCC
>Mature Secondary Structure 
AILDLANPVRFMSLSARILPWIAGAAVVTLAVGFFLAFRAPPDYQQGETVRIMYIHVPF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCH
AWLGLFGYSMMAASSIGILVWRHPLADVAHKAAAPVGATFTALCLVTGALWGRPMWGTYW
HHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEE
VWDARLTSMLVLLLLYLGLMALRAAIDDPNRAGRAAAVLTLVGFINVPIVKFSVDWWNTL
EHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHHH
HQPASVFRMGGSTIESSLLWPLLVCAIGFTLLFVALHMLGMRTEILHRRVQALEARAAAE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMA
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]