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The map label for this gene is moeZ [H]

Identifier: 154248049

GI number: 154248049

Start: 4569255

End: 4570067

Strand: Reverse

Name: moeZ [H]

Synonym: Xaut_4128

Alternate gene names: 154248049

Gene position: 4570067-4569255 (Counterclockwise)

Preceding gene: 154248050

Following gene: 154248046

Centisome position: 86.08

GC content: 70.85

Gene sequence:

>813_bases
ATGGCCTTTTCCCCCGACGAGATCGAACGCTACGCCCGCCACATCGTGCTGCACGACGTGGGCGGCCCCGGGCAGCAGAA
GCTGAAGGCGGCCACCGTGCTGGTGGTGGGCGCAGGCGGCCTCGGCGCGCCGGTGCTGCTCTATCTGGCCGCGGCGGGGG
TGGGGCGGCTGATCCTGGTCGAGGACGACGTGGTCTCCCTCTCCAACCTCCAGCGGCAGGTCATCCACCGTACCCAGGAC
GTGGGCCGGCCCAAGACCGACAGTGCCAGCGACGCCATCGCCGCCCTCAACCCCCATGTGGAACTGGTGACCCACGCGGT
AAGGCTCGACGCCGGTAACGCCCTGGACCTCATCGCCCGGGCGGACGTGGTGGTGGACGGCTCGGACAATTTCGCCACCC
GCTATCTGGTGTCGGACGCCTGCGTGCTGGCGAAAAAACCGCTGGTGACGGCGGCGCTCGGCGCCTTCGACGCTACGGTG
ACCACCCTGCGCGCCCACGAAACGGCGCCGGACGGCACCCCCAACCCCACCTATCGCTGCCTGTTTCCCGAGCCGCCGCC
GGCGGGCACGGTGCCGGCCTGCGCGGAAGCGGGTGTGCTGGGAGCACTGGCCGGGATCGCCGGATCACTGGCCGCGCTGG
AGGCAATCCGCGCCGTGGTCGGCTTCGGCGAGGGGCTGGTGGGGCGCCTGCTGATGATCGACGCCCGCGCCATGCGCTTC
GAGACCCTGAGCTATGGGTGGGACCCGGACAACCCCCTGACCGGTACCGGCGAGCGCATCACCGACCTGTCGGCGCATGT
GCGGACCCGTTAA

Upstream 100 bases:

>100_bases
GGTGAACACCACCCTCCTGCCGCTGATCGCCCGCCTGTCGGGAAACTGAGCGACAGCCACAAGGGTGACGCCGGCGGCTA
CTGGATTTAAGGATTCCGCC

Downstream 100 bases:

>100_bases
GGGGGAACCTCGCCCGCCATGAACGCACGCTACATCAGCTCTCGTATTTTATGAGCCATACGCTCCATTAGGCTCGACCA
GTCTCCTGCTATCTGCTGCC

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MAFSPDEIERYARHIVLHDVGGPGQQKLKAATVLVVGAGGLGAPVLLYLAAAGVGRLILVEDDVVSLSNLQRQVIHRTQD
VGRPKTDSASDAIAALNPHVELVTHAVRLDAGNALDLIARADVVVDGSDNFATRYLVSDACVLAKKPLVTAALGAFDATV
TTLRAHETAPDGTPNPTYRCLFPEPPPAGTVPACAEAGVLGALAGIAGSLAALEAIRAVVGFGEGLVGRLLMIDARAMRF
ETLSYGWDPDNPLTGTGERITDLSAHVRTR

Sequences:

>Translated_270_residues
MAFSPDEIERYARHIVLHDVGGPGQQKLKAATVLVVGAGGLGAPVLLYLAAAGVGRLILVEDDVVSLSNLQRQVIHRTQD
VGRPKTDSASDAIAALNPHVELVTHAVRLDAGNALDLIARADVVVDGSDNFATRYLVSDACVLAKKPLVTAALGAFDATV
TTLRAHETAPDGTPNPTYRCLFPEPPPAGTVPACAEAGVLGALAGIAGSLAALEAIRAVVGFGEGLVGRLLMIDARAMRF
ETLSYGWDPDNPLTGTGERITDLSAHVRTR
>Mature_269_residues
AFSPDEIERYARHIVLHDVGGPGQQKLKAATVLVVGAGGLGAPVLLYLAAAGVGRLILVEDDVVSLSNLQRQVIHRTQDV
GRPKTDSASDAIAALNPHVELVTHAVRLDAGNALDLIARADVVVDGSDNFATRYLVSDACVLAKKPLVTAALGAFDATVT
TLRAHETAPDGTPNPTYRCLFPEPPPAGTVPACAEAGVLGALAGIAGSLAALEAIRAVVGFGEGLVGRLLMIDARAMRFE
TLSYGWDPDNPLTGTGERITDLSAHVRTR

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=234, Percent_Identity=50.4273504273504, Blast_Score=193, Evalue=1e-49,
Organism=Homo sapiens, GI38045948, Length=158, Percent_Identity=32.9113924050633, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI23510338, Length=183, Percent_Identity=27.3224043715847, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI23510340, Length=183, Percent_Identity=27.3224043715847, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4885649, Length=153, Percent_Identity=30.718954248366, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1787048, Length=256, Percent_Identity=40.234375, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI87082356, Length=238, Percent_Identity=41.1764705882353, Blast_Score=157, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17540406, Length=253, Percent_Identity=39.1304347826087, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI193203301, Length=171, Percent_Identity=26.9005847953216, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321903, Length=220, Percent_Identity=42.2727272727273, Blast_Score=181, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6320598, Length=183, Percent_Identity=26.775956284153, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322639, Length=182, Percent_Identity=27.4725274725275, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24582879, Length=241, Percent_Identity=44.8132780082988, Blast_Score=204, Evalue=5e-53,
Organism=Drosophila melanogaster, GI28573937, Length=194, Percent_Identity=27.8350515463918, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24660640, Length=141, Percent_Identity=29.0780141843972, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28121; Mature: 27990

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFSPDEIERYARHIVLHDVGGPGQQKLKAATVLVVGAGGLGAPVLLYLAAAGVGRLILV
CCCCHHHHHHHHHHEEEECCCCCCHHHHEEEEEEEEECCCCHHHHHHHHHHCCCCEEEEE
EDDVVSLSNLQRQVIHRTQDVGRPKTDSASDAIAALNPHVELVTHAVRLDAGNALDLIAR
ECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCEEHEEE
ADVVVDGSDNFATRYLVSDACVLAKKPLVTAALGAFDATVTTLRAHETAPDGTPNPTYRC
EEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEE
LFPEPPPAGTVPACAEAGVLGALAGIAGSLAALEAIRAVVGFGEGLVGRLLMIDARAMRF
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHE
ETLSYGWDPDNPLTGTGERITDLSAHVRTR
EHEECCCCCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AFSPDEIERYARHIVLHDVGGPGQQKLKAATVLVVGAGGLGAPVLLYLAAAGVGRLILV
CCCHHHHHHHHHHEEEECCCCCCHHHHEEEEEEEEECCCCHHHHHHHHHHCCCCEEEEE
EDDVVSLSNLQRQVIHRTQDVGRPKTDSASDAIAALNPHVELVTHAVRLDAGNALDLIAR
ECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCEEHEEE
ADVVVDGSDNFATRYLVSDACVLAKKPLVTAALGAFDATVTTLRAHETAPDGTPNPTYRC
EEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEE
LFPEPPPAGTVPACAEAGVLGALAGIAGSLAALEAIRAVVGFGEGLVGRLLMIDARAMRF
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHE
ETLSYGWDPDNPLTGTGERITDLSAHVRTR
EHEECCCCCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]