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The map label for this gene is clpX

Identifier: 154247519

GI number: 154247519

Start: 4016406

End: 4017674

Strand: Direct

Name: clpX

Synonym: Xaut_3592

Alternate gene names: 154247519

Gene position: 4016406-4017674 (Clockwise)

Preceding gene: 154247518

Following gene: 154247520

Centisome position: 75.65

GC content: 63.67

Gene sequence:

>1269_bases
ATGAGCAAGACCGGCGGCAGCGACAGCAAGAACACGCTTTATTGCTCGTTCTGCGGCAAGAGCCAGCACGAGGTCAGGAA
GCTCATCGCCGGACCGACTGTGTTCATCTGCGACGAATGCGTCGAGTTGTGCATGGACATCATCCGGGAAGAGTCGAAGT
CCTCTCTGGTGAAGTCGCGGGATGGCATCCCGACCCCGAAGGAGATCCGCAAGGTCCTCGATGACTATGTCATCGGCCAG
GATCACGCGAAGAAGGTCCTCTCCGTTGCGGTGCACAATCACTACAAGCGCCTCAACCACGCCACCAAGCACGGCGACGT
GGAGCTCGCGAAGTCCAACATCCTGCTGATCGGGCCCACCGGCTCCGGCAAGACGCTGCTCGCGCAGACCCTGGCGCGCA
TCCTCGACGTGCCCTTCACCATGGCCGACGCCACCACGCTGACCGAAGCCGGCTACGTGGGTGAGGACGTGGAGAACATC
ATCCTCAAGCTGCTCCAGGCTGCCGACTACAATGTCGAGCGGGCGCAGCGCGGCATCGTCTACATCGACGAGATCGACAA
GATCAGTCGCAAATCCGACAATCCCTCCATCACCCGCGACGTGTCGGGCGAGGGTGTGCAGCAGGCGCTGCTGAAGATCA
TGGAAGGCACGGTGGCCTCGGTGCCTCCCCAGGGCGGCCGCAAGCATCCCCAGCAGGAATTCCTGCAGGTGGACACCACC
AATATCCTGTTCATCTGCGGCGGCGCCTTCGCCGGCCTCGACAAGATCATCTCCTCGCGCTCGAAGGGGTCCACCTCTAT
CGGCTTCCAGGCCAAGGTGGCCCCGCCCGAGGATCGCCGCCCCGGCGAGGTGTTCCGCGAGGTGGAGCCCGAGGATCTGC
TGAAGTACGGCCTGATCCCCGAGTTCATCGGGCGTCTGCCGGTCCTGGCGACGCTGGGTGACCTCGACGAGGAGGCCCTG
AAGAAGATCCTCTCCGAGCCGAAGAACGCGCTGGTGAAGCAGTACCAGCGCCTGTTCGAGATGGAGAATGTGGACCTGAC
CATCCACGAGGAGGCCCTCGGCGCCATCGCCCGCAAGGCGATCGAGCGCAAGACCGGCGCCCGTGGCCTCCGGTCCATCA
TGGAGAGCATCCTCCTCGACACCATGTTCGACCTCCCCGGCCTTGAAGGGGTGGAAGAGGTGGTGATCTCGCGGGAGGTG
GTCGAGCAGAGTGCGCGTCCGCTTTATATTTACGCGGACCGTGTCGGCGACGCCGGCGCCAGTGCGTGA

Upstream 100 bases:

>100_bases
TTCGGGATTGGCTGGAAATTTGCATGGTCCAATCCCCATATGTGACGCTAGCGTGATGGGCGCGTTTCGTGTCCGGATCG
GTAGATGGTAGGAGACGAAG

Downstream 100 bases:

>100_bases
CGGCGTCCGCCCCACAGCCCGCCCCCGGCCTCGCGGCATGGGGGCAGGCCGGGGCATGGTCCGAAACTCGGGCCAAACAG
GGGGGAAGACGGAACGCGCT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MSKTGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGIPTPKEIRKVLDDYVIGQ
DHAKKVLSVAVHNHYKRLNHATKHGDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLDKIISSRSKGSTSIGFQAKVAPPEDRRPGEVFREVEPEDLLKYGLIPEFIGRLPVLATLGDLDEEAL
KKILSEPKNALVKQYQRLFEMENVDLTIHEEALGAIARKAIERKTGARGLRSIMESILLDTMFDLPGLEGVEEVVISREV
VEQSARPLYIYADRVGDAGASA

Sequences:

>Translated_422_residues
MSKTGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGIPTPKEIRKVLDDYVIGQ
DHAKKVLSVAVHNHYKRLNHATKHGDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLDKIISSRSKGSTSIGFQAKVAPPEDRRPGEVFREVEPEDLLKYGLIPEFIGRLPVLATLGDLDEEAL
KKILSEPKNALVKQYQRLFEMENVDLTIHEEALGAIARKAIERKTGARGLRSIMESILLDTMFDLPGLEGVEEVVISREV
VEQSARPLYIYADRVGDAGASA
>Mature_421_residues
SKTGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGIPTPKEIRKVLDDYVIGQD
HAKKVLSVAVHNHYKRLNHATKHGDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENII
LKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
ILFICGGAFAGLDKIISSRSKGSTSIGFQAKVAPPEDRRPGEVFREVEPEDLLKYGLIPEFIGRLPVLATLGDLDEEALK
KILSEPKNALVKQYQRLFEMENVDLTIHEEALGAIARKAIERKTGARGLRSIMESILLDTMFDLPGLEGVEEVVISREVV
EQSARPLYIYADRVGDAGASA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=339, Percent_Identity=53.0973451327434, Blast_Score=325, Evalue=5e-89,
Organism=Escherichia coli, GI1786642, Length=406, Percent_Identity=72.9064039408867, Blast_Score=598, Evalue=1e-172,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=46.2264150943396, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=46.7948717948718, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=46.7948717948718, Blast_Score=275, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=392, Percent_Identity=38.0102040816327, Blast_Score=242, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=40.4858299595142, Blast_Score=168, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=418, Percent_Identity=39.9521531100478, Blast_Score=273, Evalue=4e-74,
Organism=Drosophila melanogaster, GI24648291, Length=333, Percent_Identity=49.5495495495495, Blast_Score=304, Evalue=7e-83,
Organism=Drosophila melanogaster, GI24648289, Length=333, Percent_Identity=49.5495495495495, Blast_Score=304, Evalue=8e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46242; Mature: 46110

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSR
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGIPTPKEIRKVLDDYVIGQDHAKKVLSVAVHNHYKRLNHATKHGDVELAKSNILLIGPT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECC
GSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLDKIISSRSKGSTSIGFQAKVAPPEDRRPGEVFREVEPEDLLKYGLIP
CEEEEECCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHCCCH
EFIGRLPVLATLGDLDEEALKKILSEPKNALVKQYQRLFEMENVDLTIHEEALGAIARKA
HHHCCCHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
IERKTGARGLRSIMESILLDTMFDLPGLEGVEEVVISREVVEQSARPLYIYADRVGDAGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
SA
CC
>Mature Secondary Structure 
SKTGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSR
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGIPTPKEIRKVLDDYVIGQDHAKKVLSVAVHNHYKRLNHATKHGDVELAKSNILLIGPT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECC
GSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLDKIISSRSKGSTSIGFQAKVAPPEDRRPGEVFREVEPEDLLKYGLIP
CEEEEECCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHCCCH
EFIGRLPVLATLGDLDEEALKKILSEPKNALVKQYQRLFEMENVDLTIHEEALGAIARKA
HHHCCCHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
IERKTGARGLRSIMESILLDTMFDLPGLEGVEEVVISREVVEQSARPLYIYADRVGDAGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
SA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA