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The map label for this gene is ctrA [H]

Identifier: 154247416

GI number: 154247416

Start: 3884330

End: 3885031

Strand: Reverse

Name: ctrA [H]

Synonym: Xaut_3488

Alternate gene names: 154247416

Gene position: 3885031-3884330 (Counterclockwise)

Preceding gene: 154247424

Following gene: 154247414

Centisome position: 73.18

GC content: 60.83

Gene sequence:

>702_bases
ATGCGCGTCTTGCTCATCGAGGACGACAGTGCTACGGCCCGAGGCATCGAACTGATGCTGAAGACCGAGAGCTTCAACGT
CTATACGACCAACCTCGGTGAGGAAGGCGTAGATCTCGGTAAGGTCTACGAATACGACATCATCCTTCTCGACTTGAACC
TGCCCGACATGTCAGGGTTCGAAGTCCTGCGCGCCCTGCGCGTGGCGAAGGTGAAGACACCGATCCTCATCCTCTCCGGC
CTCGCCAATACGGAAGACAAGGTGAAGGGCTTCGGCTTCGGCGCCGACGACTACCTCACCAAGCCGTTCCACAAGGACGA
GATGGTGGCGCGCATCCACGCCATCGTGCGCCGCTCCAAGGGCCACGCCCAGTCGGTGATCCAGACCGGCGACCTGGTGG
TGAACCTCGACACCAAGACCGTCGAGGTGGAGAACAACCGGGTCCACCTCACCGGCAAGGAATACCAGATGCTGGAGCTG
CTCTCGCTCCGCAAGGGCACGACCCTCACCAAGGAGATGTTCCTCAACCATCTCTACGGCGGGATGGACGAGCCGGAACT
GAAAATCATCGACGTGTTCATCTGCAAGCTGCGCAAGAAGCTCGCCAATGCGTCCGCCGGCAAGAACTATATCGAGACCG
TGTGGGGCCGCGGCTATGTGCTGCGCGAGCCCATGCTGGGCGCCGAGCGCATCGCGGTCTGA

Upstream 100 bases:

>100_bases
CTGTTAACGATTCTACACACGTAACGCGAATCACCCCGATGGCCGAGCAACAGAAGTCGGCAGCACCGACTTCTGGGTAG
TTGCGAGGAAAGGGATAGCC

Downstream 100 bases:

>100_bases
TCCCCTCTCGCCTCGCAGCCAACAGGAAAGCCCCGCATCGCGGGGCTTTTTTTCGTCTGGGGCCGAGGTAAGCACCGACT
GCGAGAGAAAACGTCACGCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRVLLIEDDSATARGIELMLKTESFNVYTTNLGEEGVDLGKVYEYDIILLDLNLPDMSGFEVLRALRVAKVKTPILILSG
LANTEDKVKGFGFGADDYLTKPFHKDEMVARIHAIVRRSKGHAQSVIQTGDLVVNLDTKTVEVENNRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANASAGKNYIETVWGRGYVLREPMLGAERIAV

Sequences:

>Translated_233_residues
MRVLLIEDDSATARGIELMLKTESFNVYTTNLGEEGVDLGKVYEYDIILLDLNLPDMSGFEVLRALRVAKVKTPILILSG
LANTEDKVKGFGFGADDYLTKPFHKDEMVARIHAIVRRSKGHAQSVIQTGDLVVNLDTKTVEVENNRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANASAGKNYIETVWGRGYVLREPMLGAERIAV
>Mature_233_residues
MRVLLIEDDSATARGIELMLKTESFNVYTTNLGEEGVDLGKVYEYDIILLDLNLPDMSGFEVLRALRVAKVKTPILILSG
LANTEDKVKGFGFGADDYLTKPFHKDEMVARIHAIVRRSKGHAQSVIQTGDLVVNLDTKTVEVENNRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANASAGKNYIETVWGRGYVLREPMLGAERIAV

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=35.7142857142857, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=35.1111111111111, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.5291479820628, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=33.0316742081448, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=32.7272727272727, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.0175438596491, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.9559471365639, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=30.1369863013699, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=29.7297297297297, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=29.5454545454545, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=29.4117647058824, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=29.5154185022026, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=24.6696035242291, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=28.0373831775701, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=24.5762711864407, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1790437, Length=160, Percent_Identity=24.375, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26159; Mature: 26159

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLIEDDSATARGIELMLKTESFNVYTTNLGEEGVDLGKVYEYDIILLDLNLPDMSGF
CEEEEEECCCCCCCCEEEEEEECCCEEEECCCCCCCCCCCEEEEEEEEEEEECCCCCCHH
EVLRALRVAKVKTPILILSGLANTEDKVKGFGFGADDYLTKPFHKDEMVARIHAIVRRSK
HHHHHHHHHHHCCCEEEEECCCCCCHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCC
GHAQSVIQTGDLVVNLDTKTVEVENNRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CHHHHHHCCCCEEEEECCEEEEEECCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLANASAGKNYIETVWGRGYVLREPMLGAERIAV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCCCCHHHCC
>Mature Secondary Structure
MRVLLIEDDSATARGIELMLKTESFNVYTTNLGEEGVDLGKVYEYDIILLDLNLPDMSGF
CEEEEEECCCCCCCCEEEEEEECCCEEEECCCCCCCCCCCEEEEEEEEEEEECCCCCCHH
EVLRALRVAKVKTPILILSGLANTEDKVKGFGFGADDYLTKPFHKDEMVARIHAIVRRSK
HHHHHHHHHHHCCCEEEEECCCCCCHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCC
GHAQSVIQTGDLVVNLDTKTVEVENNRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CHHHHHHCCCCEEEEECCEEEEEECCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLANASAGKNYIETVWGRGYVLREPMLGAERIAV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA