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The map label for this gene is cysQ [H]

Identifier: 154247414

GI number: 154247414

Start: 3882418

End: 3883260

Strand: Reverse

Name: cysQ [H]

Synonym: Xaut_3486

Alternate gene names: 154247414

Gene position: 3883260-3882418 (Counterclockwise)

Preceding gene: 154247416

Following gene: 154247413

Centisome position: 73.15

GC content: 71.89

Gene sequence:

>843_bases
ATGACCTTTCCCGTGCCCCGCGCGCCCGCCCCCACCGATGCCGCCCTGCTGGCGGGCCTTGCGGAGGCGGCGCTGGCGGC
CGGTGTCGTCATCCGCCGCATCGAGGCGGAAGGCATCACCCACCGGCAGAAATCCGACCGCAGCCCGGTCACGGAGGCGG
ACCATGCCGCCGAAGCCACCATCTTCGCTGCCCTGTCCCAGCTGATGCCCGGTGTGCCGGTGGTGGCGGAGGAGGCGACG
GCGGCGGGCACCGAGGTCATCTGCGGCAACCGCTTCGTGCTGGTCGATCCCCTCGACGGCACCCGCGAGTTCATCTCCGG
CAATGGCGAGTACACCGTGAACATCGCGGTGGTGGAGGATGGCGTTCCGGTGCTCGGCGTGGTCTATGCGCCGGCCCGCG
CTCTGCTGTTCGCCGGGCGGCCCGGCTCCGCCTTCCGAGCCATCCGCGCACCCGGCGCCCGCGTCGACGCGCAGGACTGG
ACCCCCATCGCCTGCCGCAAGGTGCAGGATGGCGCCCTCGTGGTGGCCGAAAGCCGCTCCCACGGCGACCCCGCCACCGA
CGCGCTCATCGCCCGTTACCAGGTGGCCGAGCGCATCCCGGCAGGGTCGGCGCTGAAGTTCGGCCTCATCGCCGAGGGTA
AGGCGGATTTCTATCCCCGTCTCGGGCCGGTGATGGAATGGGACAGCGCGGCGGGCCATGCCCTGGTGGTGGCGGCCGGC
GGCAGTGTCACCCGGCCGGACGGCAGCCCCCTTACCTATGGGCACTCCGAGGTCGGCTACATGGTCCACGGCTTCGTGGC
CTGGGGCTCCGGCGGACCGCCGGAGATAGGGTCCGTGGGTTAA

Upstream 100 bases:

>100_bases
CACCGCCGCACCGCACCAATGATGATTGAATCATCGCATCGACATGGCCGGCGCGCGGGGCTAGAGACTGCGTCCCGAAG
ACCCGACAAAGCCGCCCGCC

Downstream 100 bases:

>100_bases
CCCGCCGATAATTCCGGATTCGGCATGGTGATTTTCAGGTAACGCCCGACCGTCAGCGCACGGTCGACGTGCCCGCGTCA
TACTCATCGCCATAATTTGA

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MTFPVPRAPAPTDAALLAGLAEAALAAGVVIRRIEAEGITHRQKSDRSPVTEADHAAEATIFAALSQLMPGVPVVAEEAT
AAGTEVICGNRFVLVDPLDGTREFISGNGEYTVNIAVVEDGVPVLGVVYAPARALLFAGRPGSAFRAIRAPGARVDAQDW
TPIACRKVQDGALVVAESRSHGDPATDALIARYQVAERIPAGSALKFGLIAEGKADFYPRLGPVMEWDSAAGHALVVAAG
GSVTRPDGSPLTYGHSEVGYMVHGFVAWGSGGPPEIGSVG

Sequences:

>Translated_280_residues
MTFPVPRAPAPTDAALLAGLAEAALAAGVVIRRIEAEGITHRQKSDRSPVTEADHAAEATIFAALSQLMPGVPVVAEEAT
AAGTEVICGNRFVLVDPLDGTREFISGNGEYTVNIAVVEDGVPVLGVVYAPARALLFAGRPGSAFRAIRAPGARVDAQDW
TPIACRKVQDGALVVAESRSHGDPATDALIARYQVAERIPAGSALKFGLIAEGKADFYPRLGPVMEWDSAAGHALVVAAG
GSVTRPDGSPLTYGHSEVGYMVHGFVAWGSGGPPEIGSVG
>Mature_279_residues
TFPVPRAPAPTDAALLAGLAEAALAAGVVIRRIEAEGITHRQKSDRSPVTEADHAAEATIFAALSQLMPGVPVVAEEATA
AGTEVICGNRFVLVDPLDGTREFISGNGEYTVNIAVVEDGVPVLGVVYAPARALLFAGRPGSAFRAIRAPGARVDAQDWT
PIACRKVQDGALVVAESRSHGDPATDALIARYQVAERIPAGSALKFGLIAEGKADFYPRLGPVMEWDSAAGHALVVAAGG
SVTRPDGSPLTYGHSEVGYMVHGFVAWGSGGPPEIGSVG

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=240, Percent_Identity=30.4166666666667, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1790659, Length=222, Percent_Identity=41.8918918918919, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1788882, Length=235, Percent_Identity=29.7872340425532, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71995897, Length=168, Percent_Identity=32.7380952380952, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71995905, Length=168, Percent_Identity=32.7380952380952, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI193202572, Length=237, Percent_Identity=25.3164556962025, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324508, Length=334, Percent_Identity=27.8443113772455, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 28840; Mature: 28709

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFPVPRAPAPTDAALLAGLAEAALAAGVVIRRIEAEGITHRQKSDRSPVTEADHAAEAT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCCCCCCCCCCCHHHHHHH
IFAALSQLMPGVPVVAEEATAAGTEVICGNRFVLVDPLDGTREFISGNGEYTVNIAVVED
HHHHHHHHCCCCCEEECCCCCCCCEEEECCEEEEEECCCCHHHHHCCCCCEEEEEEEEEC
GVPVLGVVYAPARALLFAGRPGSAFRAIRAPGARVDAQDWTPIACRKVQDGALVVAESRS
CCCEEEEEECCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCHHEEEECCCEEEEECCCC
HGDPATDALIARYQVAERIPAGSALKFGLIAEGKADFYPRLGPVMEWDSAAGHALVVAAG
CCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECC
GSVTRPDGSPLTYGHSEVGYMVHGFVAWGSGGPPEIGSVG
CCEECCCCCCEECCCCCCCEEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TFPVPRAPAPTDAALLAGLAEAALAAGVVIRRIEAEGITHRQKSDRSPVTEADHAAEAT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCCCCCCCCCCCHHHHHHH
IFAALSQLMPGVPVVAEEATAAGTEVICGNRFVLVDPLDGTREFISGNGEYTVNIAVVED
HHHHHHHHCCCCCEEECCCCCCCCEEEECCEEEEEECCCCHHHHHCCCCCEEEEEEEEEC
GVPVLGVVYAPARALLFAGRPGSAFRAIRAPGARVDAQDWTPIACRKVQDGALVVAESRS
CCCEEEEEECCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCHHEEEECCCEEEEECCCC
HGDPATDALIARYQVAERIPAGSALKFGLIAEGKADFYPRLGPVMEWDSAAGHALVVAAG
CCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECC
GSVTRPDGSPLTYGHSEVGYMVHGFVAWGSGGPPEIGSVG
CCEECCCCCCEECCCCCCCEEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]