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The map label for this gene is hflK [H]

Identifier: 154247312

GI number: 154247312

Start: 3771909

End: 3772988

Strand: Direct

Name: hflK [H]

Synonym: Xaut_3384

Alternate gene names: 154247312

Gene position: 3771909-3772988 (Clockwise)

Preceding gene: 154247310

Following gene: 154247313

Centisome position: 71.05

GC content: 69.72

Gene sequence:

>1080_bases
ATGGCGAATATAGACACGGTACCGCGCGAGGAGAGCCCAGTCCCGCCCCAGGTCCCGCTCGAGGCCGCGCCCCCGCAGGC
GAAGGAACCGTTCGAGGCCCTGGCGCGCGATCAGGTGGCCGACATGCTGCGCCTGCCGCACTTCGGGCGCTGGGGGGCGC
TCATGGTCGCCGGCATCCTCGTGTTCCTGTGGGCGGCGAGCGGTTTCTACCGGGTCCAGCCGGACGAGCAGGGCATCGTG
CTGCGCTTCGGCAAATGGGTGTCCACGCAGGCGTCAGGGGTCCACTATCACTGGCCCTATCCCATCGAAACCGTGCTGCT
GCCCAAGACCACGCAGATCAACCAGCTGGTCATCGGCAAGCGCGACGGCTCCCGCGAGCGCAACCAGATCCTGACCGGGG
ACGAGAACATCGTCGAGGCGGAGGGCGTGGTGTTCTGGCGCATCCGCGATGCCGGGCAGTTCCTGTTCAAGGTGGCCGAC
GCGGAAGGCACGCTCAGGGTGGCGGCCGAGAGCGCCCTGCGCGAGGTCATCGGCCAGAACCCGATCCAGTCGGCGCTCTC
CGACAAGCGCCAGCAGATCGCCCAGCAGACCGAGGTGGTGCTGCAGCGGCTGCTGGACAAATACGAGGCCGGCATCACCA
TCACCCAGGTGCAGCTGCTGCGCATCGATCCGCCGCCCGCCGTCATCGACGCTTTCAACGACGTGCAGCGGGCGCGGGCG
GACCAGGAGCGGGCGCGCAACGAGGCGGAAGCCTATCGCAACGACATCCTGCCCCACGCCCGCGGCGAGGCCGAGCACAT
CACCCAGGAGGCCGCGGCCTATGGCGAGCAGGTGGTCGACCTGGCGCGCGGCGAGGCCCAGAGCTTCCTCGCCGTCGCCG
CCGCCTACGAGCAGCACAAGGATGTGACCCTGCGCCGGCTCTATCTGGAAGGCGTGGACGAACTGCTGAAGCGCTCCGGA
CGGGTGATCGTGGACCTGTCGGCCCACGGCGGCGGCGTGGTGCCCTACCTGCCCCTGATGGAGCCGGGGCCGAAGCCGGC
CGCGGTCGCCGAGGCCCCGGTCGCGGGAGCGGTCAAATGA

Upstream 100 bases:

>100_bases
AGGACGAACCGACAATTCCTGTTTAGCGCGCCCCGATGACAGTTGAAAAACGTCTTCCCAAAGGTCATCGCGCCCATTGC
CTGTCCCAAGGTCAGTCTCT

Downstream 100 bases:

>100_bases
AGCGCTATGGTTTCGTCGGGCTGGCGGCGGCGGCCATTCTCGGGGCCGTCGCCCTGTCCTTCGCCTTCACGGTGGAGGAG
ACCCAGCGGGCGCTGGTGGT

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MANIDTVPREESPVPPQVPLEAAPPQAKEPFEALARDQVADMLRLPHFGRWGALMVAGILVFLWAASGFYRVQPDEQGIV
LRFGKWVSTQASGVHYHWPYPIETVLLPKTTQINQLVIGKRDGSRERNQILTGDENIVEAEGVVFWRIRDAGQFLFKVAD
AEGTLRVAAESALREVIGQNPIQSALSDKRQQIAQQTEVVLQRLLDKYEAGITITQVQLLRIDPPPAVIDAFNDVQRARA
DQERARNEAEAYRNDILPHARGEAEHITQEAAAYGEQVVDLARGEAQSFLAVAAAYEQHKDVTLRRLYLEGVDELLKRSG
RVIVDLSAHGGGVVPYLPLMEPGPKPAAVAEAPVAGAVK

Sequences:

>Translated_359_residues
MANIDTVPREESPVPPQVPLEAAPPQAKEPFEALARDQVADMLRLPHFGRWGALMVAGILVFLWAASGFYRVQPDEQGIV
LRFGKWVSTQASGVHYHWPYPIETVLLPKTTQINQLVIGKRDGSRERNQILTGDENIVEAEGVVFWRIRDAGQFLFKVAD
AEGTLRVAAESALREVIGQNPIQSALSDKRQQIAQQTEVVLQRLLDKYEAGITITQVQLLRIDPPPAVIDAFNDVQRARA
DQERARNEAEAYRNDILPHARGEAEHITQEAAAYGEQVVDLARGEAQSFLAVAAAYEQHKDVTLRRLYLEGVDELLKRSG
RVIVDLSAHGGGVVPYLPLMEPGPKPAAVAEAPVAGAVK
>Mature_358_residues
ANIDTVPREESPVPPQVPLEAAPPQAKEPFEALARDQVADMLRLPHFGRWGALMVAGILVFLWAASGFYRVQPDEQGIVL
RFGKWVSTQASGVHYHWPYPIETVLLPKTTQINQLVIGKRDGSRERNQILTGDENIVEAEGVVFWRIRDAGQFLFKVADA
EGTLRVAAESALREVIGQNPIQSALSDKRQQIAQQTEVVLQRLLDKYEAGITITQVQLLRIDPPPAVIDAFNDVQRARAD
QERARNEAEAYRNDILPHARGEAEHITQEAAAYGEQVVDLARGEAQSFLAVAAAYEQHKDVTLRRLYLEGVDELLKRSGR
VIVDLSAHGGGVVPYLPLMEPGPKPAAVAEAPVAGAVK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=285, Percent_Identity=31.5789473684211, Blast_Score=141, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 39558; Mature: 39427

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIDTVPREESPVPPQVPLEAAPPQAKEPFEALARDQVADMLRLPHFGRWGALMVAGIL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
VFLWAASGFYRVQPDEQGIVLRFGKWVSTQASGVHYHWPYPIETVLLPKTTQINQLVIGK
HHHHHCCCEEEECCCCCCEEEEECCHHCCCCCCEEEECCCCCCEEECCCCCCCCEEEEEC
RDGSRERNQILTGDENIVEAEGVVFWRIRDAGQFLFKVADAEGTLRVAAESALREVIGQN
CCCCHHHCCEECCCCCEEECCCEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCC
PIQSALSDKRQQIAQQTEVVLQRLLDKYEAGITITQVQLLRIDPPPAVIDAFNDVQRARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHHH
DQERARNEAEAYRNDILPHARGEAEHITQEAAAYGEQVVDLARGEAQSFLAVAAAYEQHK
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
DVTLRRLYLEGVDELLKRSGRVIVDLSAHGGGVVPYLPLMEPGPKPAAVAEAPVAGAVK
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCC
>Mature Secondary Structure 
ANIDTVPREESPVPPQVPLEAAPPQAKEPFEALARDQVADMLRLPHFGRWGALMVAGIL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
VFLWAASGFYRVQPDEQGIVLRFGKWVSTQASGVHYHWPYPIETVLLPKTTQINQLVIGK
HHHHHCCCEEEECCCCCCEEEEECCHHCCCCCCEEEECCCCCCEEECCCCCCCCEEEEEC
RDGSRERNQILTGDENIVEAEGVVFWRIRDAGQFLFKVADAEGTLRVAAESALREVIGQN
CCCCHHHCCEECCCCCEEECCCEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCC
PIQSALSDKRQQIAQQTEVVLQRLLDKYEAGITITQVQLLRIDPPPAVIDAFNDVQRARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHHH
DQERARNEAEAYRNDILPHARGEAEHITQEAAAYGEQVVDLARGEAQSFLAVAAAYEQHK
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
DVTLRRLYLEGVDELLKRSGRVIVDLSAHGGGVVPYLPLMEPGPKPAAVAEAPVAGAVK
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]